LOCUS       NM_001115077            1434 bp    mRNA    linear   ROD 03-SEP-2024
DEFINITION  Mus musculus PRAME like 15 (Pramel15), mRNA.
ACCESSION   NM_001115077 XM_891640
VERSION     NM_001115077.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1434)
  AUTHORS   Tan,J., Li,Y., Li,X., Zhu,X., Liu,L., Huang,H., Wei,J., Wang,H.,
            Tian,Y., Wang,Z., Zhang,Z. and Zhu,B.
  TITLE     Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA
            demethylation
  JOURNAL   Nat Commun 15 (1), 7310 (2024)
   PUBMED   39181896
  REMARK    GeneRIF: Pramel15 facilitates zygotic nuclear DNMT1 degradation and
            DNA demethylation.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1434)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 1434)
  AUTHORS   Rong,Y., Ji,S.Y., Zhu,Y.Z., Wu,Y.W., Shen,L. and Fan,H.Y.
  TITLE     ZAR1 and ZAR2 are required for oocyte meiotic maturation by
            regulating the maternal transcriptome and mRNA translational
            activation
  JOURNAL   Nucleic Acids Res 47 (21), 11387-11402 (2019)
   PUBMED   31598710
REFERENCE   4  (bases 1 to 1434)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1434)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643. PMID: 29144450]
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from AL606926.6.
            
            On Mar 2, 2008 this sequence version replaced XM_891640.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849374
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-293               AL606926.6         54321-54613         c
            294-863             AL606926.6         53372-53941         c
            864-1434            AL606926.6         49440-50010         c
FEATURES             Location/Qualifiers
     source          1..1434
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 77.98 cM"
     gene            1..1434
                     /gene="Pramel15"
                     /gene_synonym="EG627009; Gm13125; Pramef20"
                     /note="PRAME like 15"
                     /db_xref="GeneID:627009"
                     /db_xref="MGI:MGI:3712553"
     CDS             1..1434
                     /gene="Pramel15"
                     /gene_synonym="EG627009; Gm13125; Pramef20"
                     /note="PRAME family member 20"
                     /codon_start=1
                     /product="novel preferentially expressed antigen in
                     melanoma (Prame) protein"
                     /protein_id="NP_001108549.1"
                     /db_xref="CCDS:CCDS51364.1"
                     /db_xref="GeneID:627009"
                     /db_xref="MGI:MGI:3712553"
                     /translation="MSSKPLLTLQELAAQNILRNEALAISALQYLPELFLPQLLKQAY
                     DGNHLKVLRAIVSSWPFPRLPLGALKKRTPYLETQLQVVLEEVDKLLIQEVHPREYKL
                     EVLDLRSVGQNYLNVWPGAMDDWLPKTTQTDPCCSKTVMTQPLKVLVDLQLNNRGQSR
                     LFSYLVQWSDRRKGLLQLYCNKLQIWSPSQQNYRKLSQKVNLDYVETLGLHSSCSPSF
                     LLNFAPYLRQMRNLRKLALSNIREEHIISPEKRRCIITRFTLQILKLESLQKLHLDAV
                     CFLEGHLDQLLGSVKTSLDELAVTHCNLSVSEWSHFSEFPCVSQLQQLNLENVRLTGL
                     SPEPLQVLLVKAGPTLVALDLEDCHLEDGQLYAILPALSKCFKLTKFSFYGNQISMLA
                     MKDLLHHTASLIHLRLELYPVPQDSYDYHGTPLMQRMQQHCDELMNLLKTFRNPGRVF
                     FGTDRCDQCCNRYIYNKTIMCNCRRSY"
     exon            1..293
                     /gene="Pramel15"
                     /gene_synonym="EG627009; Gm13125; Pramef20"
                     /inference="alignment:Splign:2.1.0"
     exon            294..863
                     /gene="Pramel15"
                     /gene_synonym="EG627009; Gm13125; Pramef20"
                     /inference="alignment:Splign:2.1.0"
     exon            864..1434
                     /gene="Pramel15"
                     /gene_synonym="EG627009; Gm13125; Pramef20"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgagcagca agcccttact cacactccaa gagctggcag cccagaacat tctgaggaat
       61 gaggctttgg ccatcagcgc tttgcagtac ttacctgaac tattcttacc acaactgttg
      121 aagcaagcct acgatggtaa ccatcttaag gtcctgaggg caatagtatc ttcctggcct
      181 ttccctcgcc ttcctcttgg agctctgaag aagagaacac cctacttgga gactcaatta
      241 caagttgtct tagaggaggt tgataagctg cttatccagg aggttcaccc cagggagtac
      301 aaactagaag tgctggattt acggtctgtg ggacaaaact atttgaatgt gtggcctggg
      361 gccatggatg actggttacc caagaccact caaacagatc cttgctgttc taagacagta
      421 atgacacagc ccttgaaagt actagtggac ttgcagctca acaatagagg ccagagtagg
      481 ctgttctcct acctcgttca gtggagtgat aggaggaaag ggttgttaca gctgtactgt
      541 aataagcttc agatctggtc accatcccaa caaaactaca ggaagctctc acaaaaggtg
      601 aacctggact atgtggaaac actgggcctg cattcctcct gcagtccatc cttcttgctt
      661 aactttgctc cttacttgcg ccaaatgagg aacttgcgta aacttgctct ctccaacatc
      721 cgtgaagaac acattatctc tccggagaag aggaggtgta tcatcaccag gttcaccttg
      781 cagatcctta agctggagag cctccagaag ctgcatctag atgctgtctg cttccttgag
      841 ggacacctag accagctgct tgggtccgtg aagacctcct tggatgaact ggcagtgact
      901 cactgtaatc tctcagtatc agaatggagc catttttctg agttcccatg tgtcagtcag
      961 ttgcaacaac tgaatttgga aaatgtcaga ttgactggtt taagtcctga acctctccaa
     1021 gttctgttag taaaagctgg acccaccctg gtggccttgg acttggagga ctgtcacctt
     1081 gaagatggcc agctctatgc catcctacct gccctgagca agtgcttcaa gctcaccaag
     1141 ttcagtttct atgggaacca aatctctatg cttgccatga aggacctact acaccacact
     1201 gccagcttga tacatctaag gctggagcta taccctgttc ctcaggacag ttatgactac
     1261 catggtactc ccctcatgca aaggatgcaa caacattgtg atgagcttat gaatctactg
     1321 aaaacattta ggaatccagg cagagtcttc ttcggtactg accgctgtga tcagtgctgc
     1381 aatagatata tctataacaa aaccattatg tgtaattgtc ggagatctta ctag
//
