LOCUS       NM_029948               2460 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus PRAME like 13 (Pramel13), mRNA.
ACCESSION   NM_029948
VERSION     NM_029948.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2460)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2460)
  AUTHORS   Li,N., Yu,J., Zhou,M., Qiu,F., Wang,X. and Wang,Z.
  TITLE     MAGE-B4, a binding partner of PRAMEF12, is dispensable for
            spermatogenesis and male fertility in mice
  JOURNAL   Biochem Biophys Res Commun 675, 46-53 (2023)
   PUBMED   37451217
  REMARK    GeneRIF: MAGE-B4, a binding partner of PRAMEF12, is dispensable for
            spermatogenesis and male fertility in mice.
REFERENCE   3  (bases 1 to 2460)
  AUTHORS   Wang,Z., Xu,X., Li,J.L., Palmer,C., Maric,D. and Dean,J.
  TITLE     Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a
            factor essential for spermatogenesis in mice
  JOURNAL   Nat Commun 10 (1), 5196 (2019)
   PUBMED   31729367
  REMARK    GeneRIF: In male mice, genetic ablation of Pramef12 arrests
            spermatogenesis and results in sterility.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2460)
  AUTHORS   Madissoon,E., Tohonen,V., Vesterlund,L., Katayama,S., Unneberg,P.,
            Inzunza,J., Hovatta,O. and Kere,J.
  TITLE     Differences in gene expression between mouse and human for
            dynamically regulated genes in early embryo
  JOURNAL   PLoS One 9 (8), e102949 (2014)
   PUBMED   25089626
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2460)
  AUTHORS   Williams,J.A., Kondo,N., Okabe,T., Takeshita,N., Pilchak,D.M.,
            Koyama,E., Ochiai,T., Jensen,D., Chu,M.L., Kane,M.A., Napoli,J.L.,
            Enomoto-Iwamoto,M., Ghyselinck,N., Chambon,P., Pacifici,M. and
            Iwamoto,M.
  TITLE     Retinoic acid receptors are required for skeletal growth, matrix
            homeostasis and growth plate function in postnatal mouse
  JOURNAL   Dev Biol 328 (2), 315-327 (2009)
   PUBMED   19389355
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK019795.1.
            
            On Apr 6, 2007 this sequence version replaced NM_029948.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK019795.1, BC066168.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2460              AK019795.1         2-2461
FEATURES             Location/Qualifiers
     source          1..2460
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 77.98 cM"
     gene            1..2460
                     /gene="Pramel13"
                     /gene_synonym="4930569K13Rik; Pramef12"
                     /note="PRAME like 13"
                     /db_xref="GeneID:77632"
                     /db_xref="MGI:MGI:1924882"
     exon            1..108
                     /gene="Pramel13"
                     /gene_synonym="4930569K13Rik; Pramef12"
                     /inference="alignment:Splign:2.1.0"
     exon            109..431
                     /gene="Pramel13"
                     /gene_synonym="4930569K13Rik; Pramef12"
                     /inference="alignment:Splign:2.1.0"
     CDS             139..1530
                     /gene="Pramel13"
                     /gene_synonym="4930569K13Rik; Pramef12"
                     /codon_start=1
                     /product="PRAME family member 12"
                     /protein_id="NP_084224.1"
                     /db_xref="CCDS:CCDS18905.1"
                     /db_xref="GeneID:77632"
                     /db_xref="MGI:MGI:1924882"
                     /translation="MSLRATPTLLQLAMQSLLRDEALAISALQDLPMELLPPLFKDAI
                     THKRLNILRKMVQVWPFPCLPLGGLMKMKTPYLDILQTVLDGVDALLDQNTHPRNYKL
                     QVLDLRALHKDFWTVWAGDTTTSCAPGVKCRRKIQKRGPKIEAKQNSLKVFIDLYLKP
                     RALDTCLSYVFLWARERKALLQLGCKKLKINTVAIQNIVKILEMLDLDYVEEVEVCCT
                     WKLSTLAIFAPYLGQMKNLLSIILSHIHVPASITPEEEKQLVSQFTSQFSNLQYLQDL
                     SLDSIDFLKGQMDQLFRCLEVPLEILSITDSKISESDLQSLSQCPGIRQLKHLNLSGV
                     ILTDISPEPLRVLLERVAATLKTLDLENCMIMDSQLDVLLPALSQCAQLIMFNYLRNP
                     ISVSILERLLHHTSGLNYLSLEMYSTPWEIYGAQGASYHKRLEQLREELSKAMQHLEH
                     NRTVWFSVAPCLP"
     exon            432..1016
                     /gene="Pramel13"
                     /gene_synonym="4930569K13Rik; Pramef12"
                     /inference="alignment:Splign:2.1.0"
     exon            1017..2460
                     /gene="Pramel13"
                     /gene_synonym="4930569K13Rik; Pramef12"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2441..2446
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pramel13"
                     /gene_synonym="4930569K13Rik; Pramef12"
                     /note="hexamer: AATAAA"
     polyA_site      2459
                     /gene="Pramel13"
                     /gene_synonym="4930569K13Rik; Pramef12"
                     /note="major polyA site"
ORIGIN      
        1 gtcttagtct gccctggtca ggggaattca gttctttggc ggatattcct acgcccactt
       61 cagtagaaga tctctggcct ccggagttca gcggagactt cattgcagga tcatcagtct
      121 ccctacagat ctgtgaagat gagcttgcgt gccacaccca cactcctaca gctcgcaatg
      181 caaagcctgc tgagggatga ggccttggcc atctctgctc tgcaggacct gcccatggag
      241 ctcctcccac cactcttcaa agatgccatc actcacaaac gacttaacat cctgaggaag
      301 atggtgcagg tctggccttt tccctgtctc ccgctgggtg gtctgatgaa gatgaagaca
      361 ccatacctgg atatcttgca aaccgtactg gatggggttg atgcactgct tgaccagaat
      421 actcacccca ggaattacaa actgcaagtt ctggatttgc gggctttgca caaggacttc
      481 tggaccgtat gggctggaga tacgacaaca tcttgcgctc caggggtcaa gtgtaggaga
      541 aaaatacaaa agagaggtcc aaagatagaa gccaagcaaa actcattgaa agtgtttata
      601 gacctgtacc tcaaaccaag agccttggat acatgcctgt cctatgtctt cctgtgggcg
      661 agagagagaa aagctttgtt gcagcttggc tgtaagaagc tgaagatcaa cacagtagct
      721 atccagaata ttgtgaagat tctggaaatg ctagacctgg actatgtgga ggaagtagaa
      781 gtatgttgta cctggaagct gtctactctg gccatctttg ctccttacct gggccaaatg
      841 aaaaatcttc tctcgatcat tctctctcac attcatgtgc ctgcctctat taccccagag
      901 gaggagaagc agctggtcag ccagttcacc tctcagtttt ccaacctgca gtacctccag
      961 gacctctccc tggactccat cgacttcctc aaaggtcaaa tggaccagtt gttcaggtgc
     1021 ctggaggtcc ccttggagat cctctctatt actgattcca agatttcaga atcagacttg
     1081 cagtccctgt cccagtgtcc aggcatccga cagctcaaac acctgaacct gagtggtgtc
     1141 attctgaccg acataagtcc tgagcctctt cgagtcctgc tggagagagt tgcagccacc
     1201 ctgaagaccc tggacttgga gaactgtatg attatggact cccagcttga tgtcctcttg
     1261 cctgccctga gccaatgtgc tcagcttatc atgttcaact acttaaggaa ccccatctca
     1321 gtgtctattc tggagcgcct gctccaccac acctccgggc tgaactattt aagcttggag
     1381 atgtattcta ccccttggga gatttatggt gcccagggtg cttcctacca taagaggcta
     1441 gaacagctta gagaggagct gagcaaggcg atgcagcatc tagaacacaa cagaacggtc
     1501 tggttcagcg tcgcgccctg tcttccttga ggcaaccagg ccatacgagt cagagcccaa
     1561 gcttcatcag gcagggctgt tcccctaact gagtacttat atggcaagtg attccttcta
     1621 gctcttggga acagaatcct ctggtgtaga tgaatccttt agaaaatatc agggtggggg
     1681 gtagggtggg gatgggggat tggttgagca gccgaggcaa cctcccaaat gttgacctaa
     1741 agagttgatg tcccttggga catgtgtatt tagcagtgag agatgaagtt tctagatgga
     1801 gaaacccttg agggtgttta cttcatgggt ggagggaaag aagttgccag tgtgttcttc
     1861 cccacttcgg gctatagggt aaatggaata aaccatgtta cagcttggca ggcccaagta
     1921 gccactggca gtcaccacct taatctccag ctctgagccc tagagacttt gctcaccagc
     1981 agtcccatct atccaagaag gctacagttc tgctcagagg gccgtgtcag tgtagattct
     2041 aaacaatctc actgagagga atgcaaagag agatggtgct gttaggtgct gaggaccacc
     2101 acaaacagtg agaagggata ggcttaaact cataagtagc caacaactaa ccatacatca
     2161 tgcttgaaaa tcagtaaagc tgacacatag taaagggatg tatttgttag tcctaaggta
     2221 cctaagttac agctgaccac caagaacaga tgtatctatc acctgacctt tgtttggtct
     2281 acagatgatt ggccctattg cactgtgggt gggcggcttt attagtaata cgctactggg
     2341 gattaaatgt aggactttgt gcacgctagg caaatgttct accactatga atctttaaat
     2401 cattacactg ctgtgtatgt aggggaattt tcagtgttca aataaacatg tggcaagtcc
//
