LOCUS       NM_001355724            3845 bp    mRNA    linear   ROD 01-MAY-2024
DEFINITION  Mus musculus PRAME like 12 (Pramel12), transcript variant 2, mRNA.
ACCESSION   NM_001355724 XM_006538856
VERSION     NM_001355724.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3845)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3845)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   3  (bases 1 to 3845)
  AUTHORS   Hansen,G.M., Markesich,D.C., Burnett,M.B., Zhu,Q., Dionne,K.M.,
            Richter,L.J., Finnell,R.H., Sands,A.T., Zambrowicz,B.P. and
            Abuin,A.
  TITLE     Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
  JOURNAL   Genome Res 18 (10), 1670-1679 (2008)
   PUBMED   18799693
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK029142.1, BQ745938.1 and BC056931.1.
            
            On Sep 26, 2017 this sequence version replaced XM_006538856.3.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC056931.1, SRR1660817.213774.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-496               AK029142.1         2-497
            497-1158            BQ745938.1         1-662
            1159-3816           AK029142.1         1225-3882
            3817-3845           BC056931.1         3256-3284
FEATURES             Location/Qualifiers
     source          1..3845
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 77.65 cM"
     gene            1..3845
                     /gene="Pramel12"
                     /gene_synonym="4732496O08Rik; Pramef8"
                     /note="PRAME like 12"
                     /db_xref="GeneID:242736"
                     /db_xref="MGI:MGI:2140473"
     exon            1..666
                     /gene="Pramel12"
                     /gene_synonym="4732496O08Rik; Pramef8"
                     /inference="alignment:Splign:2.1.0"
     exon            667..979
                     /gene="Pramel12"
                     /gene_synonym="4732496O08Rik; Pramef8"
                     /inference="alignment:Splign:2.1.0"
     CDS             693..2135
                     /gene="Pramel12"
                     /gene_synonym="4732496O08Rik; Pramef8"
                     /codon_start=1
                     /product="PRAME family member 8"
                     /protein_id="NP_001342653.1"
                     /db_xref="CCDS:CCDS38944.1"
                     /db_xref="GeneID:242736"
                     /db_xref="MGI:MGI:2140473"
                     /translation="MSVQDPPTLLQLSVQRLLRDEALAISSLQYLPRALFPLLFKEAF
                     NHRQTNVLRAMVAVWPFPFLPLGTLMKTPHLEILQAVLDGVDMLWTQKVLPRRRKLQV
                     LDLRNVYHDFWDVWVGPEDGDHSAETVCEKQIAKRLHQYALRRRLKVVTDLCLRFHLN
                     EHQAYLLQWAQQRRSSIRLCCVKMQIWALPVYTVRKVLMVFQPDSIQELELNTGWSLS
                     TLVHFASYLDQMRNLQKLLLTRIHKNTFKVLNTSSDIQKCITKFVSQFSKLNSLQHLS
                     MNGIYFSSEHMKQLFRYLKTPLETLSITMCKLSHLDLNSLSQSQSLHQLKQLNLRLVK
                     LIDLRPVPFHDLLRSVAGTLQTLELEGCWMVDSQLTALLPALSQCSQLTRVNFYDNDI
                     SMAVLKDLLYHTASLSQLTQELYPAPLECYDDTGDVLMGRFVQLCPELMETLITVRQP
                     KNVSFATYICHECCQRCVYGLETKLCRCRQ"
     exon            980..1567
                     /gene="Pramel12"
                     /gene_synonym="4732496O08Rik; Pramef8"
                     /inference="alignment:Splign:2.1.0"
     exon            1568..3821
                     /gene="Pramel12"
                     /gene_synonym="4732496O08Rik; Pramef8"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3800..3805
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pramel12"
                     /gene_synonym="4732496O08Rik; Pramef8"
                     /note="hexamer: AATAAA"
     polyA_site      3821
                     /gene="Pramel12"
                     /gene_synonym="4732496O08Rik; Pramef8"
                     /note="major polyA site"
ORIGIN      
        1 acaggagttc tgggattaag ggcgtgaacc gcttccgcgg ctttcaggat ttttttccct
       61 catctccgtg aatttggctt tacctcccca gagatccgcc tgcatctgcc tctccgcgga
      121 tgtgcgcggt tttcccggct gtttttttct ttctttcttt tttttttttc cttttccacg
      181 gagactatgt tgtcaatcaa tacagaaaca gaaaacgccc agacgtggcg gaaactcagt
      241 catccaatca gaggacggct tgtggttgac aggcgggact acaaaccgga aatgtgagac
      301 agaatacgcg gaccgagccg ggggaggggc gaccaaaaag aaaacaaaaa acaaaaaaca
      361 aaccgccgaa aaacaaaaaa ataaaaaccg cttcaggccg gaagtataaa acggaacccg
      421 gaagtgtggg accggatacg gctaaaacac ttcaggccgg aagtgcgaga cagatacgga
      481 tgaaaacgct gcaggccgga agtgcgagac ggatgaaaac gcctcaggcc ggaagtttga
      541 agtgaagatg gctataaaag ctttagagaa gctcgggaag acactcacca gcacttggag
      601 tccgagcttg gactgactgc ctgggcctgc tgggattctg agttctgcca tcagttcttg
      661 tttctggatc cttgacactg aagatctgaa ggatgagtgt ccaggaccca cccacactcc
      721 tgcagctgtc agtacagaga ctactgaggg acgaggccct ggccatttct tctctgcagt
      781 accttcccag ggcgcttttc ccactgctct tcaaggaagc cttcaatcac agacaaacta
      841 atgtcctgag ggccatggtg gcagtgtggc cctttccctt cctccctctg gggaccctga
      901 tgaagactcc ccacctggag atcttgcagg ctgtgctgga tggagtagac atgctttgga
      961 cacagaaggt tcttcccaga aggaggaagc tccaagtgct ggacctgagg aatgtgtacc
     1021 atgacttctg ggatgtttgg gttggaccag aggatggaga ccactcagca gagactgtgt
     1081 gtgaaaagca gatagcaaag cgccttcatc aatatgcact gaggcgacgt ttgaaggtgg
     1141 tcactgacct gtgcctcagg ttccatttga atgaacacca agcatacttg ttacagtggg
     1201 cccagcagag aagaagttcc atacggctat gctgtgtgaa gatgcagatt tgggctttgc
     1261 ctgtgtacac tgtcaggaag gtcttgatgg tgttccagcc agacagcatc caagaattgg
     1321 aactaaatac aggttggagc ctgtccactc tggtgcattt tgcatcttac ctggaccaga
     1381 tgagaaacct tcaaaaactc cttttaacac ggattcacaa gaacaccttc aaggttctaa
     1441 atacctcctc ggacatccag aagtgtatca ccaagtttgt ctctcagttc tccaaactca
     1501 actctctcca gcatctctcc atgaatggca tctacttttc cagtgagcac atgaaacagt
     1561 tgttcaggta cctgaagacc ccgttggaga ctctgtccat caccatgtgc aagctttcac
     1621 atttagactt gaattccttg tcccagagtc agagcctcca tcagctcaaa cagctgaacc
     1681 tgagacttgt gaagttgatt gacttacgtc ctgtgccttt ccacgacctc ctcaggagtg
     1741 ttgcaggcac cctgcagacc ctagaactgg agggctgttg gatggtggac tcccagctca
     1801 ctgccctcct gcctgccctg agccagtgtt cccagctcac cagggtcaac ttctatgaca
     1861 atgacatctc catggctgtt ctaaaggacc ttctgtatca cacagccagt ctgagccagc
     1921 tgacccagga gctgtatcct gcccctctgg agtgctatga tgacacgggt gatgtcctta
     1981 tgggaagatt tgtccaactt tgtcctgagc ttatggagac actcattact gtaaggcagc
     2041 ccaagaatgt ctcctttgct acgtatatct gccatgaatg ttgccagcgc tgtgtctatg
     2101 gcctggagac aaaactttgt cgttgtcggc agtaaatagg ggcaggttgt tttttgatac
     2161 tgagaaatga aagtctagga acaggtcttg catcaagaga acccaaagca catggccaca
     2221 cactgctcat tatctgggaa cccaaatggt gtgctggagg gttagaccac aaagactgag
     2281 cttctagaga acaatgggac ccaggacaga tgtttgtgga atcaaaagac aatccttcat
     2341 ttcttttctt ttgttcattc ttcattgttt ttttgttttc ttttaagatt tatttatttt
     2401 atatctgggt ggtttacctg catatatgta tccttggtgc ctatagagtt cagatgtggg
     2461 cattggatcc cctggaactg gagttttgga tggctgtgac ccatcatatg agtcttctgc
     2521 aagaacaagt gctcttgcct gctgaaccat ctctccagcc ccagttgagc actttctaaa
     2581 taaatgagtt ctgtcaggtc atgataatga atgactttct ccttctcaca tggtagtaaa
     2641 atggccagat tttagaacct ggatgttctg gtgtccttct caccagattt ttggagcttg
     2701 gtttcagtgt tgttcttttc ctgtggcttg gctggaaaga tcctgtgctg tctgacctct
     2761 ctagacatct gtaatggcaa acctggttgt cagcctgccc acttctgtaa caactagaac
     2821 ccacttgatg aaacagcaca tgccctaaat ggtgaccatg cattctcttg gcagcattgg
     2881 taaagagaga gaagaaggaa gctgtgctgc cgagtttgtc ctacttcttt gggcagtatt
     2941 cattttcttc aggattttaa catagcctga aagccagcag ctctctagga gcctaggatt
     3001 gcagcaccag attggactgc agagacttcc agctttacga atgaactccc agatccttgg
     3061 ccttttcatt gtgagccagc cattgtcaga ctgcgcagac cacagccggt aagccagtct
     3121 agtaaacctc atatgttcct gatacacacg gaactgtcag ttctgctcct ttagccttta
     3181 gagaaccctg accactacag catcaaggtc aagtgaaagc cgtcagatgt cttccctcct
     3241 ttacctttgc ctgggcatct gttatgtctc acttgtgtgc tcattgcttt agtatacaaa
     3301 atgtcaatgt aaaatgagca atgcattctc ctctgagggg tttgggggaa tggtagagga
     3361 atccaatcta gtacacttag actaggaggt attatggaca tatcaaagat ggctgaagtg
     3421 aagtcaaaga taacaaagag caaagaaaat ggaggctaag ccactttgct ttatcactct
     3481 ttattttttt ctctctcttt catggtcaca tattgcccag gctggccttg aaatctcctg
     3541 cctccacctt ctaaatgcta agattactga agtatggcac cttggctagt ttgtagtcca
     3601 catgtatgta agactctatt tttcagggct tctagcctcc ggctgtccct ttgaaaacaa
     3661 aggtctccag tagatgtccc tgtcccctaa aggattgaca ggccttaaga actgcattat
     3721 aggtgtccag gagtaaactt ttattttgtt aataagtatc taagcctagc cattgcgatc
     3781 ctctgtataa tctggttgca ataaagaatt ttggttcata aaaaaaaaaa aaaaaaaaaa
     3841 aaaaa
//
