LOCUS       NM_031377               2440 bp    mRNA    linear   ROD 04-FEB-2025
DEFINITION  Mus musculus PRAME like 1 (Pramel1), mRNA.
ACCESSION   NM_031377
VERSION     NM_031377.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2440)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2440)
  AUTHORS   Yang,M., Diaz,F., Krause,A.R.T., Lei,Y. and Liu,W.S.
  TITLE     Synergistic enhancement of the mouse Pramex1 and Pramel1 in
            repressing retinoic acid (RA) signaling during gametogenesis
  JOURNAL   Cell Biosci 14 (1), 28 (2024)
   PUBMED   38395975
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2440)
  AUTHORS   Yang,M., Ma,W., Oatley,J. and Liu,W.S.
  TITLE     Mouse Pramel1 regulates spermatogonial development by inhibiting
            retinoic acid signaling during spermatogenesis
  JOURNAL   Development 150 (21) (2023)
   PUBMED   37781892
  REMARK    GeneRIF: Mouse Pramel1 regulates spermatogonial development by
            inhibiting retinoic acid signaling during spermatogenesis.
REFERENCE   4  (bases 1 to 2440)
  AUTHORS   Mistry,B.V., Zhao,Y., Chang,T.C., Yasue,H., Chiba,M., Oatley,J.,
            Diaz,F. and Liu,W.S.
  TITLE     Differential expression of PRAMEL1, a cancer/testis antigen, during
            spermatogenesis in the mouse
  JOURNAL   PLoS One 8 (4), e60611 (2013)
   PUBMED   23565261
REFERENCE   5  (bases 1 to 2440)
  AUTHORS   Dade,S., Callebaut,I., Mermillod,P. and Monget,P.
  TITLE     Identification of a new expanding family of genes characterized by
            atypical LRR domains. Localization of a cluster preferentially
            expressed in oocyte
  JOURNAL   FEBS Lett 555 (3), 533-538 (2003)
   PUBMED   14675769
REFERENCE   6  (bases 1 to 2440)
  AUTHORS   Wang,P.J., McCarrey,J.R., Yang,F. and Page,D.C.
  TITLE     An abundance of X-linked genes expressed in spermatogonia
  JOURNAL   Nat Genet 27 (4), 422-426 (2001)
   PUBMED   11279525
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL611930.25.
            
            On Jul 14, 2009 this sequence version replaced NM_031377.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC132399.1, AF285578.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-103               AL611930.25        12226-12328
            104-421             AL611930.25        14215-14532
            422-988             AL611930.25        14835-15401
            989-2440            AL611930.25        16153-17604
FEATURES             Location/Qualifiers
     source          1..2440
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 77.64 cM"
     gene            1..2440
                     /gene="Pramel1"
                     /note="PRAME like 1"
                     /db_xref="GeneID:83491"
                     /db_xref="MGI:MGI:1890541"
     exon            1..103
                     /gene="Pramel1"
                     /inference="alignment:Splign:2.1.0"
     exon            104..421
                     /gene="Pramel1"
                     /inference="alignment:Splign:2.1.0"
     CDS             129..1505
                     /gene="Pramel1"
                     /note="preferentially expressed antigen in melanoma-like
                     1"
                     /codon_start=1
                     /product="preferentially expressed antigen in
                     melanoma-like protein 1"
                     /protein_id="NP_113554.1"
                     /db_xref="CCDS:CCDS18888.1"
                     /db_xref="GeneID:83491"
                     /db_xref="MGI:MGI:1890541"
                     /translation="MSCKTPPTLQELAENSLLKNQDLAISALDDIPSLFFPSLFKKAC
                     RNRYVGIIKAMVQAWPFPCLPLGAMISRKTAYRRILEIILYGLDALLSQKVPHSRCKL
                     QVLDLRVMPLKLWNRLPVFGTAGCSENPAVVGHSGTEVKQPVKVLVDLVLKESPLDST
                     ESFLVQWVDNRNGLVSLCCCKLQIWAMSMYYHRKLLEILDLDSVQELRMYCISNPVCL
                     LNFAPYLGRMRNLRCLILSHLWQTFSMTPVEKQQVITQFTSQFLKLKCLQILHLDTVF
                     FLEGHLDELFWWLKTPLETLSVIDCNLSKSDWFHISEFQCTSQLKHLNLKWVKLTHLS
                     PEPLRVLLLKSASTLTSLDLEGCQMMDSQLSAILPALRCCTQLTKFNFHGNYISMPIL
                     RELAYNVVKQKSQQSKIRFIPSCSHHSGLEFEAISQPHIVFVDVDRTTGEQEQVLFYA
                     ICSGEYVL"
     exon            422..988
                     /gene="Pramel1"
                     /inference="alignment:Splign:2.1.0"
     exon            989..2440
                     /gene="Pramel1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgcttcctg tcaggtctct gtgagtttga ggccagcggg ggagacagag ggaccggagg
       61 gctccggggc ggctcggaga catcttgctt ctgtccatct ctggaatcct tcctgaagat
      121 ccatcaggat gagctgcaag actccaccca cactccagga actggcagag aacagcctcc
      181 tgaagaacca ggacttggct atctctgctc tggatgacat accctcactt ttcttcccat
      241 cactgttcaa aaaggcctgc agaaatagat atgttgggat cataaaggcg atggtgcagg
      301 cgtggccctt cccctgtctt cctctggggg ccatgatcag taggaagact gcctacagga
      361 gaatcttaga gattatcctg tatgggcttg atgccttgct ttcccagaaa gttccccaca
      421 gcaggtgcaa gctgcaagtg ctggatttac gggttatgcc tttgaagctg tggaacaggt
      481 tgcctgtgtt tgggactgct ggctgcagtg agaatccagc agtggtgggc cattcgggaa
      541 cagaggtgaa acagccagtg aaggtgctgg tagacttggt cctcaaggaa agcccactag
      601 attccacaga gtccttcctc gttcagtggg tggataacag gaatggtttg gtgagtttgt
      661 gctgttgcaa gctgcagatc tgggctatgt ccatgtatta ccacagaaaa cttttggaga
      721 ttttggatct ggactctgtc caggagctgc gtatgtactg catcagtaat cctgtctgcc
      781 tgcttaactt cgccccttac ttgggtcgca tgaggaacct gcgctgcctc atcctctctc
      841 acctctggca gaccttctcg atgaccccgg tggagaagca gcaggttatt acccagttca
      901 cgtctcagtt cctcaaactg aaatgcctcc agatcctgca tctggatact gtcttcttcc
      961 tagagggtca tctggatgag ctattctggt ggctgaagac acccttagag accctgtctg
     1021 tgattgattg taatctctca aaatcagact ggttccatat atctgagttc cagtgcacaa
     1081 gtcagctaaa acacctgaat ttgaaatggg tcaaactgac ccatttgagc ccagagcccc
     1141 ttcgagttct gttactaaaa tctgcatcta ccctaacatc cctggatttg gagggctgtc
     1201 aaatgatgga ctctcaactc agtgccatcc tacctgctct gagatgctgt acacagctca
     1261 ccaagtttaa tttccatggg aactatatct ccatgcctat cctgagggag ctggcatata
     1321 acgttgtcaa gcagaaatcc caacagtcaa agatacgctt tatcccaagc tgtagtcatc
     1381 acagtggtct ggagtttgag gccatttctc agcctcatat tgtgtttgta gatgtggatc
     1441 ggactactgg ggagcaagaa caagtcttgt tttatgctat ttgttctgga gaatatgtgt
     1501 tatgatatct ctacaatgta ttaggacttg ttagactcct acctaatgag atacagattt
     1561 aagctctctt gtggacactg ggatgtgtct ggtcagagta tgcacaacac atgcttttag
     1621 actgcagttc ttgcgagtga gaagagaaag ttgatgctag agtgcaaaca agtgagagta
     1681 tttgacatag ggaatgtggg acacattgac agaagtcatg ggagtgggtt ctggttgggc
     1741 aggtacaaaa gggcattcct ccagcctggt gtttttttga tttttgtagt aaaaaatggg
     1801 accatctgtc ctacctggat gattcaaatc ctgtgactgc taggaacaaa cttgttttat
     1861 gctatttgct ggttcttcta ctttgatctt ctgagtgctg agtataggct tatagcacca
     1921 gacctggttc cctgtagttc ctttaacatg tggctatacc tctcatcttt ctagtcaaac
     1981 ccagtatttt atatagtagc agtttttgtg gggctagaga gatggcttat cagttgagag
     2041 cacttgatgc ttttgtagag tacctgggtt tgattcccct catttacatg gtggttcaca
     2101 gtcatccaga actacttatg gggtgcatga ggcatgcatg tagtgcatag acatacatgt
     2161 aggtgaaaca ctcagacatg taactctaaa ataatttaaa aattgatttg tactgatgag
     2221 actgaatgtc tagttgaggc agccagcacc cagtatttct atgacagaca ctgctaagtc
     2281 atgtatttat actcgtaaaa tgctacctat gagcttagca aattgaacca ggaatatatg
     2341 gatgagtaga caataaactc tagcaggaaa aaccccaagc ttttatgaca atattaaaca
     2401 ccccagacca ctgaaggatg caatccccat cccgaatcat
//
