LOCUS       NM_001081214            5244 bp    mRNA    linear   ROD 07-FEB-2025
DEFINITION  Mus musculus peroxisome proliferative activated receptor, gamma,
            coactivator-related 1 (Pprc1), transcript variant 1, mRNA.
ACCESSION   NM_001081214 XM_358330
VERSION     NM_001081214.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5244)
  AUTHORS   Alkaissi,H., Ekstrand,J., Jawad,A., Nielsen,J.B., Havarinasab,S.,
            Soderkvist,P. and Hultman,P.
  TITLE     Genome-Wide Association Study to Identify Genes Related to Renal
            Mercury Concentrations in Mice
  JOURNAL   Environ Health Perspect 124 (7), 920-926 (2016)
   PUBMED   26942574
REFERENCE   2  (bases 1 to 5244)
  AUTHORS   Villena,J.A.
  TITLE     New insights into PGC-1 coactivators: redefining their role in the
            regulation of mitochondrial function and beyond
  JOURNAL   FEBS J 282 (4), 647-672 (2015)
   PUBMED   25495651
  REMARK    Review article
REFERENCE   3  (bases 1 to 5244)
  AUTHORS   Zhai,N., Sun,C., Gu,W., He,X., Shan,A., Sun,H., Lu,N., Cui,B. and
            Ning,G.
  TITLE     Resistance to high-fat diet-induced obesity in male heterozygous
            Pprc1 knockout mice
  JOURNAL   Endocr J 62 (7), 633-644 (2015)
   PUBMED   25994039
  REMARK    GeneRIF: these results indicated an elevated basal metabolic rate
            and lipid metabolic alteration of male Pprc1(+/-) mice on high-fat
            diet, suggesting the significant role of Pprc1 in controlling
            mitochondrial gene expression and energy metabolic processes
REFERENCE   4  (bases 1 to 5244)
  AUTHORS   Shang,Y., Doan,C.N., Arnold,T.D., Lee,S., Tang,A.A., Reichardt,L.F.
            and Huang,E.J.
  TITLE     Transcriptional corepressors HIPK1 and HIPK2 control angiogenesis
            via TGF-beta-TAK1-dependent mechanism
  JOURNAL   PLoS Biol 11 (4), e1001527 (2013)
   PUBMED   23565059
REFERENCE   5  (bases 1 to 5244)
  AUTHORS   He,X., Sun,C., Wang,F., Shan,A., Guo,T., Gu,W., Cui,B. and Ning,G.
  TITLE     Peri-implantation lethality in mice lacking the PGC-1-related
            coactivator protein
  JOURNAL   Dev Dyn 241 (5), 975-983 (2012)
   PUBMED   22411706
  REMARK    GeneRIF: Homozygous deficient PPRC1 mice failed to form egg
            cylinders and died after implantation but before embryonic day 6.5,
            whereas mice heterozygous for PPRC1 were viable, fertile and
            indistinguishable from their wild-type littermates.
REFERENCE   6  (bases 1 to 5244)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 5244)
  AUTHORS   Papin,J. and Subramaniam,S.
  TITLE     Bioinformatics and cellular signaling
  JOURNAL   Curr Opin Biotechnol 15 (1), 78-81 (2004)
   PUBMED   15102471
  REMARK    Review article
REFERENCE   8  (bases 1 to 5244)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   9  (bases 1 to 5244)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   10 (bases 1 to 5244)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC140233.3.
            
            On Feb 6, 2007 this sequence version replaced XM_358330.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC066048.1, SRR10223971.18128.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-205               AC140233.3         83761-83965
            206-379             AC140233.3         88625-88798
            380-526             AC140233.3         89366-89512
            527-628             AC140233.3         89624-89725
            629-3497            AC140233.3         89834-92702
            3498-3551           AC140233.3         92886-92939
            3552-3609           AC140233.3         94451-94508
            3610-3677           AC140233.3         95243-95310
            3678-4407           AC140233.3         96261-96990
            4408-4542           AC140233.3         98499-98633
            4543-4609           AC140233.3         98741-98807
            4610-4731           AC140233.3         98924-99045
            4732-4883           AC140233.3         99405-99556
            4884-5244           AC140233.3         99771-100131
FEATURES             Location/Qualifiers
     source          1..5244
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 38.75 cM"
     gene            1..5244
                     /gene="Pprc1"
                     /gene_synonym="A930018M19; mKIAA0595; PRC"
                     /note="peroxisome proliferative activated receptor, gamma,
                     coactivator-related 1"
                     /db_xref="GeneID:226169"
                     /db_xref="MGI:MGI:2385096"
     exon            1..205
                     /gene="Pprc1"
                     /gene_synonym="A930018M19; mKIAA0595; PRC"
                     /inference="alignment:Splign:2.1.0"
     CDS             53..4987
                     /gene="Pprc1"
                     /gene_synonym="A930018M19; mKIAA0595; PRC"
                     /note="isoform 1 is encoded by transcript variant 1;
                     peroxisome proliferator-activated receptor gamma
                     coactivator-related protein 1; PGC-1-related coactivator"
                     /codon_start=1
                     /product="peroxisome proliferator-activated receptor gamma
                     coactivator-related protein 1 isoform 1"
                     /protein_id="NP_001074683.1"
                     /db_xref="CCDS:CCDS38005.1"
                     /db_xref="GeneID:226169"
                     /db_xref="MGI:MGI:2385096"
                     /translation="MAARRGRRDRVAPPPTGGPGPDPGGGVRGGSWASRSQAPYGTGG
                     SVSAAEQVHEEGNDSSFVSLSRLGPSLREKDLEMEELILQDETLLETMQSYMDASLIS
                     LIEDFGESRLSLEDQNEMSLLTALTEILDNADSENLSPFDTIPDSELLVSPRESSSLH
                     KLLNLSRTPPERDLITPIDPLGPSTGSSRVSGVEVPLADSPWDFSPPPFLETSSPKLP
                     SWRPSRPRPRWGQSPPPQQRSDGEEEEEVAGFSGQMLAGKLDNSVNNVLDFPMHLACP
                     EEEGTAEGADAPASAPGDESISSLSELVRAMHPYCLPNLTHLASLEGELEGQADADAD
                     ELTLPEGCVVLEIVGQAATTGDDLEIPVVVRQIPSGSQSVLLDESLGSSPALQLLMPT
                     MESETEAAVPEVAPCPDEELPLSSACLLEPREIMESLTPKEPQSLPASASQGSQKVPR
                     KGRKKKNKEQPTACVEACTRRLRSSSRGQSTVSAEVNSQAGSSQKQPQEELQREAAAL
                     QSRGKPRAWARAWAAALEKTGSENLERSAGQDSPAEEDALDLCPKLLETSQANPTLSL
                     NDSAQADSMPVDSVEGDSPAVGNAAPGDQASSGTELVGSLPVGPNLTSPVLADKKGIE
                     PAVAIPTSDNLSPADVLANTVAADPVPNDPAPADPVLVKCRPTDPRRAAAAAAAAAQG
                     SRPSLQSADHPKVVSPEGKDVVGPLKVEGSTSATTQEAKPRPLSLSEYRQRRQQRQTE
                     AEDRNSQPPVVGKWPSLPETPTELADIPCLVPSAPARKTAPQRSPIAVPETVSVGSNP
                     VSPTPEPSASKLMVSTHSEQVSSHEMPLAVRPPPPPLPSVSPAGPIPSTVPAPLPPFP
                     PSVPPLLPLPSGGHGVPRLPPPPLQPPGLPVSMRQMPPDPYTQYAPVPPWSCYPSVSP
                     PGYSCLPPPPTMPIVSGTPGTYAVPPTCNVPWVPPPAPVSPYSSSCAYGSLGWGPGLQ
                     QPPFWSTVSPPPLSSVPTGRAVPPTPVEPSGDPAGPPEDVLPGPVTPSLSSGPASPAA
                     PPVEPTKPEAQPVPVSPQPKHKVSTLVQSPQIKAPPTLSTEGVVFEESVSERLKSETQ
                     ENRPKEKPISTAIKSVPVPKQSAVAKLPAVHPARLRKLSFLPTPRAQGPEDVVQAFIS
                     EIGIEASDLSSLLEQFEKSEAKKECPLPASADSLAVGNSGIDIPQEKKPLDRLQAPEL
                     ANVAGLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQEGTLKPEGITEAKPPATACLQ
                     EGAHSPSPVHVGSGDHDYCVRSRTPPKRMPALVISEVGSRWNVKRHQDITIKPVLSLG
                     SAAPPLPCTATSQEPLDHRTSVEQADPSAPCFAPSTLLSPEASPCRSEMNARTPPEPS
                     DKQQSMRCYRKACRSVSPSSRGWQGRRGRSSRSVSSGSSRTSEASSSSSVSSSSRSRS
                     RSRSRSFSPPNKRWRRSSCSSSGRSRRCSSSSSSSSSSSSCSSRSRSPSVSPCRRSDR
                     RRRYSSYRANDHYQRQRVLQKERAIEERRVVFIGKIPGRMTRSELKQRFSVFGEIEEC
                     TIHFRVQGDNYGFVTYRYAEEAFAAIESGHKLRQADEQPFDLCFGGRRQFCKRSYSDL
                     DSNREDFDPAPVKSKFDSLDFDTLLKQAQKNLRR"
     exon            206..379
                     /gene="Pprc1"
                     /gene_synonym="A930018M19; mKIAA0595; PRC"
                     /inference="alignment:Splign:2.1.0"
     exon            380..526
                     /gene="Pprc1"
                     /gene_synonym="A930018M19; mKIAA0595; PRC"
                     /inference="alignment:Splign:2.1.0"
     exon            527..628
                     /gene="Pprc1"
                     /gene_synonym="A930018M19; mKIAA0595; PRC"
                     /inference="alignment:Splign:2.1.0"
     exon            629..3497
                     /gene="Pprc1"
                     /gene_synonym="A930018M19; mKIAA0595; PRC"
                     /inference="alignment:Splign:2.1.0"
     exon            3498..3551
                     /gene="Pprc1"
                     /gene_synonym="A930018M19; mKIAA0595; PRC"
                     /inference="alignment:Splign:2.1.0"
     exon            3552..3609
                     /gene="Pprc1"
                     /gene_synonym="A930018M19; mKIAA0595; PRC"
                     /inference="alignment:Splign:2.1.0"
     exon            3610..3677
                     /gene="Pprc1"
                     /gene_synonym="A930018M19; mKIAA0595; PRC"
                     /inference="alignment:Splign:2.1.0"
     exon            3678..4407
                     /gene="Pprc1"
                     /gene_synonym="A930018M19; mKIAA0595; PRC"
                     /inference="alignment:Splign:2.1.0"
     exon            4408..4542
                     /gene="Pprc1"
                     /gene_synonym="A930018M19; mKIAA0595; PRC"
                     /inference="alignment:Splign:2.1.0"
     exon            4543..4609
                     /gene="Pprc1"
                     /gene_synonym="A930018M19; mKIAA0595; PRC"
                     /inference="alignment:Splign:2.1.0"
     exon            4610..4731
                     /gene="Pprc1"
                     /gene_synonym="A930018M19; mKIAA0595; PRC"
                     /inference="alignment:Splign:2.1.0"
     exon            4732..4883
                     /gene="Pprc1"
                     /gene_synonym="A930018M19; mKIAA0595; PRC"
                     /inference="alignment:Splign:2.1.0"
     exon            4884..5244
                     /gene="Pprc1"
                     /gene_synonym="A930018M19; mKIAA0595; PRC"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5117..5122
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pprc1"
                     /gene_synonym="A930018M19; mKIAA0595; PRC"
                     /note="hexamer: AATAAA"
     polyA_site      5139
                     /gene="Pprc1"
                     /gene_synonym="A930018M19; mKIAA0595; PRC"
                     /note="major polyA site"
ORIGIN      
        1 tgggcgaggc ggcgccggcg atcagagcag cgctgggtgt tcaggggcca agatggcggc
       61 gcgccgggga cggagagacc gagtcgcgcc gcctccgact gggggcccgg gtcctgaccc
      121 tggcggtgga gtgcgtggcg gcagttgggc gagtcgaagc caagcgccgt atgggaccgg
      181 gggctccgtg agcgccgcgg agcaggtcca tgaggaaggg aatgactcta gctttgtcag
      241 tctttctcga ctgggcccct ctctgaggga gaaagacctg gaaatggagg aactgatact
      301 gcaggatgag accctcctgg agaccatgca gagctacatg gacgcctccc ttatatccct
      361 cattgaggat tttggagaga gcagattatc tctggaggac cagaatgaaa tgtcgctgct
      421 cacagctctg acggagatct tggacaatgc agattctgag aacctgtccc cttttgacac
      481 cattcctgat tcagagctgc tcgtgtcccc tcgggagagc tcctctctgc acaagctgct
      541 caatctctct cggacacccc cagaacgtga ccttatcacc ccaattgacc ctttggggcc
      601 cagcacagga agtagtcggg tgagtggggt tgaggtgcct cttgcagact ctccatggga
      661 cttctctccg cctcctttct tggaaacttc ttcccctaag ctgcctagct ggagaccctc
      721 gagaccaaga cctcgatggg gtcagtcccc tcctcctcag cagcgcagtg atggggaaga
      781 ggaggaggag gtcgccggtt tcagtggtca gatgcttgct ggcaaactcg acaactctgt
      841 gaacaatgtc ctggacttcc ccatgcacct ggcatgccct gaggaagaag gcacagccga
      901 gggagcagat gcgccagcgt cagcccctgg tgacgagagc atctcctcct tgagtgagct
      961 ggttcgggcc atgcatccct actgcttgcc caacctcacc cacttggcat cccttgaggg
     1021 tgaacttgag ggacaggctg atgctgacgc tgacgagttg acgctgcctg agggctgtgt
     1081 tgtactggag attgttggcc aggcagccac aactggtgat gacctcgaga tcccagtcgt
     1141 ggtgcggcag attccttctg gatcccagtc tgtgctcctg gatgagtctc taggaagcag
     1201 tcctgccttg cagttactca tgcccaccat ggagtccgag accgaagctg ctgtgcctga
     1261 agttgctcct tgccccgatg aagaattacc actgagctcc gcctgcttat tggagcccag
     1321 ggaaatcatg gagtcattga cacccaagga acctcagagc ctacctgcca gtgcaagtca
     1381 gggttctcag aaagttccca gaaagggtag gaagaagaag aacaaggaac agccaacagc
     1441 ctgtgtggaa gcctgtacca ggcggctgag gtcatcttct cgaggacagt ctactgtgtc
     1501 tgcagaggtg aactctcagg caggcagttc acagaaacag ccccaggaag agcttcagag
     1561 agaggctgct gcccttcaga gcagagggaa gccacgggct tgggctcggg cctgggcagc
     1621 tgccttagag aagacagggt ccgagaattt agagagaagt gcgggacagg atagtcctgc
     1681 tgaagaagac gcactggatc tctgtcctaa gctgcttgag accagccaag ccaaccccac
     1741 tctctcatta aatgactctg ctcaagctga ctccatgcct gttgactctg ttgaaggtga
     1801 ttcccctgca gttggcaatg ctgcacctgg tgatcaggct tcatctggta cagagctggt
     1861 tggttctctc ccagtaggcc caaacctgac tagcccagtc ctggctgaca agaaaggaat
     1921 tgaacctgca gtggctattc ccacttcgga taacttgtct ccagctgatg tcctagcaaa
     1981 cacagtggca gctgaccctg ttccaaatga ccctgctcca gcagatcctg tgctagttaa
     2041 gtgcagaccc actgatccta ggcgtgctgc agcagcagca gcagcagcag ctcaggggag
     2101 tcgtccttcc ctacagtccg cagaccatcc taaggtcgtc agccctgaag gcaaggatgt
     2161 tgtaggtcct ctgaaggtgg aaggtagtac cagcgctaca acccaggaag ccaaacctcg
     2221 gcctctcagc ctatctgagt accgtcagcg aaggcagcaa cggcaaacgg aagcagaaga
     2281 caggaattct cagcccccag ttgttggcaa gtggcctagt ctcccagaga cccccacaga
     2341 actggcagat atcccttgcc ttgttccatc agccccagcc aggaagacag ctccacagag
     2401 aagccctata gctgtaccag agactgtgtc tgtgggttct aatcctgttt cccctactcc
     2461 tgagccatct gcaagcaaac ttatggtttc aactcactct gaacaggtgt catctcatga
     2521 gatgccactt gcagttagac caccccctcc tcctttgccg tctgtgtctc ctgctggacc
     2581 catcccgtcc acggtgcccg ctcctttgcc tcctttccct ccgagtgtac cgcctttgct
     2641 tcctcttcct tcaggtggcc atggagtccc ccgcctgccc ccacctcctt tgcaacctcc
     2701 tggacttcca gtatcaatga gacaaatgcc acctgacccc tatactcagt atgcccctgt
     2761 gccaccctgg tcttgttacc cctctgtgtc ccctccgggc tattcttgtt tgcccccacc
     2821 accaacgatg cccatagtat ctggtactcc tggtacctat gctgtgcccc caacttgcaa
     2881 tgtgccttgg gtaccccctc ctgcaccagt ttcaccttac agctccagct gtgcctatgg
     2941 atcccttggg tggggcccag ggctgcaaca gcctcccttt tggtctactg tttctccacc
     3001 tccgttgtct tcagtcccta ctggaagagc tgttcccccg acccccgtgg aacccagtgg
     3061 tgatcccgct ggtcctcctg aagatgtgct tcctgggcca gtgactcctt ccctaagctc
     3121 cgggccggcc agccccgcag ctccaccagt agaacctaca aagccggagg ctcagccagt
     3181 gcctgtatct ccccagccga aacacaaagt gtccaccttg gtacagagtc cccagatcaa
     3241 ggctccaccg actttgtcta ctgagggtgt agtttttgag gagtctgtat cagagaggct
     3301 aaagtctgag acccaggaga acagaccaaa ggagaagccc atctctacag ctatcaagtc
     3361 tgtccctgtg ccaaagcaga gcgctgttgc aaagctacct gctgtccatc cagcccgtct
     3421 aaggaagctg tccttcctgc ccaccccacg tgctcagggt cctgaggatg tggtgcaggc
     3481 gttcatcagt gagattggga tcgaagcatc agatctgtcg agtctgttgg agcagtttga
     3541 gaagtcagaa gccaaaaagg agtgtcctct cccggcttct gctgacagct tggctgtagg
     3601 aaactcaggc attgacattc cccaggagaa gaagccctta gaccggttac aagccccaga
     3661 actggccaac gtggcagggc tcacccctcc agctacccct ccccaccagt tatggaaacc
     3721 cctggctgct gtctcactct tggcgaaagc caaatctcct aaatccaccg cccaagaggg
     3781 aaccctgaag cctgaaggaa ttacagaggc caaacctcca gctacagcct gcctccaaga
     3841 aggggcccac agccctagtc cagtccatgt gggctctggg gaccatgact attgtgtccg
     3901 aagcaggaca cccccaaaaa ggatgcctgc cctagtcatc tcagaggtgg gctcccgatg
     3961 gaatgtcaag cgccatcagg acatcaccat caagcctgtg ttgtcattgg gctcagctgc
     4021 acccccactc ccatgcacgg ctacttccca ggagcctctt gatcacagga ctagcgttga
     4081 gcaggcagat ccttcagcgc cttgttttgc cccatccacc ttgctgtctc ctgaggcttc
     4141 accctgccgg agtgaaatga acgctaggac tccccctgag ccctcagaca agcagcagtc
     4201 aatgcgctgt taccgaaaag cctgcagatc agtcagcccc tcaagtaggg gctggcaagg
     4261 ccgccgtggc cgcagtagcc gttctgtcag ctctgggtcc agccggacca gtgaagcgtc
     4321 ctcgtcctca tcggtgtctt cctcatcccg atcccggtcc cggtccaggt ccaggtcctt
     4381 ctcccccccc aacaagaggt ggcgaaggtc cagctgcagt tcctctggac ggtccagaag
     4441 gtgttcatcc tcctcctcct cctcctcttc ctcctcatcg tgcagttcca gaagccggtc
     4501 tccctctgtg tccccttgca ggagaagtga ccggaggcgg cggtacagct cttaccgtgc
     4561 aaatgaccat taccaaaggc agagagtgct acagaaggag cgtgcaatag aagagagaag
     4621 ggtggtcttc attgggaaaa tacctggccg aatgactcgg tcggagctga aacagaggtt
     4681 ctctgttttt ggagaaattg aggagtgtac cattcatttt cgtgtccaag gtgacaacta
     4741 tggtttcgtc acttaccgtt atgctgaaga ggcatttgca gccattgaga gtggccacaa
     4801 gttgcggcag gcagacgagc agccctttga tctctgcttt gggggccgaa ggcagttctg
     4861 caagaggagt tactctgacc ttgactccaa tcgggaagac tttgatcctg ctcctgtaaa
     4921 gagcaaattc gattcacttg actttgatac attgttgaaa caggcccaga agaacctcag
     4981 gaggtaaccc tgggcattcc tcccctaccc attttctctg gaggtgtcca gcctcttcca
     5041 accccctccc caactctagg ggagagctgc tagtgtggaa aatgactgtt ttataaggaa
     5101 atggagaaaa aagttcaata aaaatgtgtt aaattgggat ttttaagtgg tatttggttt
     5161 ttaataacag gtgttgaaca aattaacttg aatttctatg taaggtggtg ggggggggaa
     5221 ctctaataaa catgaactag aggg
//
