LOCUS       NM_028999               4979 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus protein phosphatase 6, regulatory subunit 3 (Ppp6r3),
            transcript variant 1, mRNA.
ACCESSION   NM_028999
VERSION     NM_028999.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4979)
  AUTHORS   Yang,Y., Reid,M.A., Hanse,E.A., Li,H., Li,Y., Ruiz,B.I., Fan,Q. and
            Kong,M.
  TITLE     SAPS3 subunit of protein phosphatase 6 is an AMPK inhibitor and
            controls metabolic homeostasis upon dietary challenge in male mice
  JOURNAL   Nat Commun 14 (1), 1368 (2023)
   PUBMED   36914647
  REMARK    GeneRIF: SAPS3 subunit of protein phosphatase 6 is an AMPK
            inhibitor and controls metabolic homeostasis upon dietary challenge
            in male mice.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4979)
  AUTHORS   Al-Barghouthi,B.M., Rosenow,W.T., Du,K.P., Heo,J., Maynard,R.,
            Mesner,L., Calabrese,G., Nakasone,A., Senwar,B., Gerstenfeld,L.,
            Larner,J., Ferguson,V., Ackert-Bicknell,C., Morgan,E., Brautigan,D.
            and Farber,C.R.
  TITLE     Transcriptome-wide association study and eQTL colocalization
            identify potentially causal genes responsible for human bone
            mineral density GWAS associations
  JOURNAL   Elife 11, e77285 (2022)
   PUBMED   36416764
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4979)
  AUTHORS   Nakano,Y., Wiechert,S. and Banfi,B.
  TITLE     Overlapping Activities of Two Neuronal Splicing Factors Switch the
            GABA Effect from Excitatory to Inhibitory by Regulating REST
  JOURNAL   Cell Rep 27 (3), 860-871 (2019)
   PUBMED   30995482
REFERENCE   4  (bases 1 to 4979)
  AUTHORS   Stefansson,B. and Brautigan,D.L.
  TITLE     Protein phosphatase 6 subunit with conserved Sit4-associated
            protein domain targets IkappaBepsilon
  JOURNAL   J Biol Chem 281 (32), 22624-22634 (2006)
   PUBMED   16769727
REFERENCE   5  (bases 1 to 4979)
  AUTHORS   Cobellis,G., Nicolaus,G., Iovino,M., Romito,A., Marra,E.,
            Barbarisi,M., Sardiello,M., Di Giorgio,F.P., Iovino,N., Zollo,M.,
            Ballabio,A. and Cortese,R.
  TITLE     Tagging genes with cassette-exchange sites
  JOURNAL   Nucleic Acids Res 33 (4), e44 (2005)
   PUBMED   15741177
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4979)
  AUTHORS   Ballif,B.A., Villen,J., Beausoleil,S.A., Schwartz,D. and Gygi,S.P.
  TITLE     Phosphoproteomic analysis of the developing mouse brain
  JOURNAL   Mol Cell Proteomics 3 (11), 1093-1101 (2004)
   PUBMED   15345747
REFERENCE   7  (bases 1 to 4979)
  AUTHORS   Nishimura,M., Yokoi,N., Miki,T., Horikawa,Y., Yoshioka,H.,
            Takeda,J., Ohara,O. and Seino,S.
  TITLE     Construction of a multi-functional cDNA library specific for mouse
            pancreatic islets and its application to microarray
  JOURNAL   DNA Res 11 (5), 315-323 (2004)
   PUBMED   15747579
REFERENCE   8  (bases 1 to 4979)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   9  (bases 1 to 4979)
  AUTHORS   Brady,K.P., Rowe,L.B., Her,H., Stevens,T.J., Eppig,J.,
            Sussman,D.J., Sikela,J. and Beier,D.R.
  TITLE     Genetic mapping of 262 loci derived from expressed sequences in a
            murine interspecific cross using single-strand conformational
            polymorphism analysis
  JOURNAL   Genome Res 7 (11), 1085-1093 (1997)
   PUBMED   9371744
REFERENCE   10 (bases 1 to 4979)
  AUTHORS   Saijoh,Y., Fujii,H., Meno,C., Sato,M., Hirota,Y., Nagamatsu,S.,
            Ikeda,M. and Hamada,H.
  TITLE     Identification of putative downstream genes of Oct-3, a pluripotent
            cell-specific transcription factor
  JOURNAL   Genes Cells 1 (2), 239-252 (1996)
   PUBMED   9140067
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB661794.1, AK035236.1, CF727136.1, CF537891.1, CK619000.1,
            AV456025.1 and BP760563.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN01164131,
                              SAMN01164135 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-21                BB661794.1         2-22
            22-1483             AK035236.1         2-1463
            1484-2141           CF727136.1         1-658
            2142-2952           AK035236.1         2035-2845
            2953-3562           AK035236.1         2856-3465
            3563-4055           CF537891.1         164-656
            4056-4472           CK619000.1         216-632
            4473-4911           AV456025.1         1-439               c
            4912-4979           BP760563.1         29-96               c
FEATURES             Location/Qualifiers
     source          1..4979
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 3.21 cM"
     gene            1..4979
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /note="protein phosphatase 6, regulatory subunit 3"
                     /db_xref="GeneID:52036"
                     /db_xref="MGI:MGI:1921807"
     exon            1..109
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /inference="alignment:Splign:2.1.0"
     exon            110..257
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /inference="alignment:Splign:2.1.0"
     exon            258..490
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /inference="alignment:Splign:2.1.0"
     CDS             264..2885
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /note="isoform 1 is encoded by transcript variant 1;
                     sporulation-induced transcript 4-associated protein;
                     serine/threonine-protein phosphatase 6 regulatory subunit
                     3; pluripotent cell-specific 3; SAPS domain family, member
                     3"
                     /codon_start=1
                     /product="serine/threonine-protein phosphatase 6
                     regulatory subunit 3 isoform 1"
                     /protein_id="NP_083275.1"
                     /db_xref="CCDS:CCDS50341.1"
                     /db_xref="GeneID:52036"
                     /db_xref="MGI:MGI:1921807"
                     /translation="MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKL
                     IEFLLKAECLEDLVSFIIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESL
                     LMKLYSFLLNESPLNPLLASFFSKVLSILISRKPEQIVDFLKKKRDFVDLIIKHIGTS
                     AIMDLLLRLLTCIEPPQPRQDVLNWLNEERIIQRLVEIVHPSQEEDRHSNASQSLCEI
                     VRLSRDQMLQVQNSTEPDPLLATLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLL
                     ETRRPTFEGHIEICPPGMSHSACSVNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWG
                     ILDPPVGNTRLNVIRLISSLLQTNTSSINGDLMELNSIGVILDMFFKYTWNNFLHTQV
                     EICIALILASPFENAENGTITDQDSTGDNLLLKHLFQKCQLIERILEAWDTNEKKQAE
                     GGRRHGYMGHLTRIANCIVHSTDKGPNSALVQQLIKDLPDEVRERWETFCTNSLGETN
                     KRNTVDLVTTCHIHSSSDDEIDFKDTGFSQDSSLQQAFSDYQMQQMTSNFIDQFGFND
                     EKFADQDDIGNVSFDRVSDINFTLNTNESGNIALFEACCKERIQQFDDGGSDEEDIWE
                     EKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQDLFESSSANTEDKMEVDLNEPPT
                     WSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKESLRSNS
                     PVEMETSTESVDPLTPGAAALATQPEAPGSMAMEASSDGEEDAESTDKVTETVMNGGM
                     KETLSLTVDAKTETAVFKSEEEKLSTSQDAACKDAEETPEPAEAKCTAPLTPSSSPEQ
                     RTDQPSMPSDPSVNGPV"
     exon            491..677
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /inference="alignment:Splign:2.1.0"
     exon            678..815
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /inference="alignment:Splign:2.1.0"
     exon            816..881
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /inference="alignment:Splign:2.1.0"
     exon            882..994
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /inference="alignment:Splign:2.1.0"
     exon            995..1108
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /inference="alignment:Splign:2.1.0"
     exon            1109..1238
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /inference="alignment:Splign:2.1.0"
     exon            1239..1391
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /inference="alignment:Splign:2.1.0"
     exon            1392..1541
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /inference="alignment:Splign:2.1.0"
     exon            1542..1606
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /inference="alignment:Splign:2.1.0"
     exon            1607..1722
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /inference="alignment:Splign:2.1.0"
     exon            1723..1808
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /inference="alignment:Splign:2.1.0"
     exon            1809..1895
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /inference="alignment:Splign:2.1.0"
     exon            1896..1993
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /inference="alignment:Splign:2.1.0"
     exon            1994..2048
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /inference="alignment:Splign:2.1.0"
     exon            2049..2179
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /inference="alignment:Splign:2.1.0"
     exon            2180..2301
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /inference="alignment:Splign:2.1.0"
     exon            2302..2455
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /inference="alignment:Splign:2.1.0"
     exon            2456..2562
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /inference="alignment:Splign:2.1.0"
     exon            2563..2713
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /inference="alignment:Splign:2.1.0"
     exon            2714..2833
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /inference="alignment:Splign:2.1.0"
     exon            2834..4957
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4929..4934
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /note="hexamer: AATAAA"
     polyA_site      4957
                     /gene="Ppp6r3"
                     /gene_synonym="4930528G08Rik; 9130026N02Rik; D19Bwg1430e;
                     D19Ertd703e; mKIAA1558; Pp6r3; Ppcs3; Pptcs3; Sapl; Saps3"
                     /note="major polyA site"
ORIGIN      
        1 aactcaaggc ctgcttgata cgtccgccat tttgggcgct tcgctgatgg tgtcggtgaa
       61 cctttttccc gcctgagcgc gactaactgc gggtcttggg cgcctccagg aacacttctg
      121 tttcatacaa tatcctttca tacttctgct aatctgctaa tgtaatttgg aagatagctg
      181 tcaccaggat aacctgtaat gggcaaggag ccacagagaa gaaaacattt cttttagttt
      241 taaccttgct ttcaaagaac agcatgtttt ggaaatttga tcttcactca tcatcccaca
      301 tagacacgct tctagagaga gaagatgtga cactgaagga gctaatggat gaggaggatg
      361 ttctacagga gtgtaaagca cagaaccgca agctcataga atttctgtta aaagcagaat
      421 gtctggaaga tttagtctca ttcattatag aagaaccacc tcaagatatg gatgagaaga
      481 tccgatacaa gtatccaaat atatcttgtg agttgctcac atctgatgtc tcccagatga
      541 atgatagact gggggaagat gagtccttgc taatgaaatt gtatagcttc ctcctaaatg
      601 agtccccctt gaacccacta ctcgccagtt tcttcagcaa ggtgctaagt attcttatca
      661 gcagaaaacc agaacagatt gtggatttct tgaaaaagaa gcgtgatttt gtggatctca
      721 ttataaagca cataggaact tctgctatca tggatttatt gctcaggctc ttgacatgta
      781 ttgagcctcc acaacccagg caagatgttc tgaattggct aaatgaggag aggattatcc
      841 agaggcttgt ggaaatagtt cacccatcgc aagaagaaga tcggcattca aatgcctcac
      901 aatcactttg tgaaattgtt cgcctgagca gagaccagat gttacaagtt cagaacagta
      961 cagagccaga ccccctgctt gccactctag aaaagcaaga aattattgag cagcttctgt
     1021 caaatatttt tcacaaggag aagaatgaat cggccatagt cagtgcaatt cagattttgc
     1081 tgactttgct tgagactcga cggccaacgt ttgaaggcca tatagaaatc tgccccccgg
     1141 gcatgagtca ttcagcttgt tcagttaaca agagtgttct tgaagccatc cgaggaagac
     1201 ttggatcttt ccatgaactc ctactcgagc cacccaagaa aagtgtgatg aagactacat
     1261 ggggtatatt ggacccacct gtggggaata ctcgattaaa tgtcattagg ttgatatcca
     1321 gcctgctcca aaccaatacc agcagcataa atggagacct gatggaactg aacagcattg
     1381 gcgtcatatt ggatatgttc ttcaagtaca catggaataa ctttctacac acgcaagtgg
     1441 aaatttgcat tgctctcatt ctggccagtc cttttgagaa tgcagagaat ggcacaatta
     1501 ctgatcaaga ctccactggt gacaatttgt tattgaagca tctttttcaa aagtgtcagt
     1561 taatagagcg aatacttgaa gcctgggaca caaatgagaa gaaacaggct gaaggaggac
     1621 gacggcatgg ttacatggga caccttacga ggatagctaa ctgtattgtg cacagcactg
     1681 acaagggtcc gaacagtgcg ttagtacagc agctcatcaa agatcttccc gatgaagtca
     1741 gggagcggtg ggagacgttc tgcacgaact ccttaggaga gacgaacaag aggaacacgg
     1801 tagatctagt tacaacctgc catattcatt catccagtga tgatgaaatt gactttaaag
     1861 acacgggttt ctcacaggat tcctctttac agcaagcctt ttctgattat cagatgcaac
     1921 aaatgacgtc caattttatt gaccagtttg gcttcaacga tgagaagttt gcagaccaag
     1981 acgacattgg caatgtttct tttgatcggg tgtcagatat caactttact ctcaatacaa
     2041 atgaaagtgg aaatattgcc ctgtttgaag catgttgtaa agaacggata caacaatttg
     2101 atgatggcgg ctctgatgaa gaggatatct gggaggagaa gcacattgca tttactcccg
     2161 aatcccagag gaggtccagc tctggcagta cggacagtga agaaagtaca gactctgaag
     2221 aagaagatgg ggccaaacaa gacctgtttg agtccagcag tgcaaacaca gaggacaaaa
     2281 tggaggtgga tctgaatgag ccacccacct ggtcagccaa ctttgacgtc ccaatggaaa
     2341 ccacccatgg tgctccctta gactccgtgg gatccgatgt ctggagcaca gaggagccaa
     2401 tgccaactaa agagacaggc tgggcttcct tttcagagtt cacatcctcc ctgagcacaa
     2461 aggagtcttt aaggagtaat tcgcctgtgg aaatggaaac cagcactgaa tccgtggacc
     2521 ccttgacacc tggtgcagct gccttggcca ctcagccaga ggcaccaggc agtatggcca
     2581 tggaagccag ctcagatggg gaagaggatg ctgagagtac agacaaggta actgagaccg
     2641 tgatgaatgg cggcatgaag gaaacactca gcctcactgt agacgccaag acagagactg
     2701 cagtcttcaa aagtgaggaa gaaaaactgt ctacctctca agatgctgct tgcaaagatg
     2761 cagaagagac cccagagcca gcagaggcca agtgcacagc tcccctgact cccagcagta
     2821 gtcccgagca aaggaccgac cagccaagca tgccaagcga cccatcagtt aatggccctg
     2881 tatgatgagt gacgtccact gctgctgact gaggactgca ggccaccacc acccaggggc
     2941 tctggagggc tcacccagag ctactgagcc accactactg cactctgcaa gagatcagaa
     3001 ccagcagcct ttctgtttct agattctaag atgctgtaca gagagactca gacatgtaaa
     3061 acactgcaca ttgacaaata ccaagaattt ttttgcgtat gtttatattg tattgatcta
     3121 aatactgggt agcctgtgac accagatctt gccgcccatg taataatagt aatgatacat
     3181 agttcagatg gttgtaagaa tagttttata aagtgactac acagatctat tgtattcgaa
     3241 acataactat ttgacaatta ttagtgtgac caaagtatta ggcagttttc atacattttc
     3301 caccttgtac aaaattctga attcattttt cttccaggtt ggcacggagc tgtcgatgga
     3361 aaagccctct gcgtgttata ttttggttgt tctgacttac aaagtgattt tgaataagaa
     3421 atacttggtg tttttttata acccactttc aattggtaac tgttttctgt attgtttcag
     3481 gcggatcaaa tgcttgagtc ttggtggaga ttaagtattt attgctacaa cttagttgat
     3541 gaattgctgt tcttgtaaag ccatatgttc tgttaaggtc tggtttgctc agagcgtttc
     3601 tttctgcagg tgaaacacta gaatattgga gtgtacatgg ctgtggttag aattttaggg
     3661 gggttggggg gtgtttgttt tttgttttgt tttggtagtt catccgcctt ttaacccatt
     3721 caccaaaatg tcccttgtca gcaagtatca ctgatggcta tttcagagtg gtctgcaccc
     3781 acactgctct gtgtcacaga ggtgagtctg gaatgctcat gtggtgacag ggtagagtgt
     3841 gcccatcacg cgggctggct gtaacagaat cacaacctgg catccaagca tgtttcttgt
     3901 tttactgtac cttgtgaggt tttcacttgt aaaccagtgg attttagaac tggtttgtgt
     3961 gtatatagtg attatggata ctaattcagt gtaatttata attttctatg tcagcgtaaa
     4021 cacatcctag cctcctccaa cagctgaagc aatggcctgt gcactgccgc ggcatcgggt
     4081 gaagagctca gtcacctcgc ctcttgcact tttagatgca gatcagtttt tcattctata
     4141 atagaaaata ttcacatatt tttacatcat ttgttttttc ctgaccagta tttaaaacca
     4201 aaaggatatt ctgaaaaaat ggccaacaag ttttttagaa ccagcatccc aagcagtgtg
     4261 cctacatgac atcgcgtatg gagatagagt cgagtgtcca atgccttact ccttactcgc
     4321 ttctcactgt acacagtgca agggaccacc tcaggtggcc gaggcaggcc tggtcaccag
     4381 gctcagtggg cagcaggaag ccctgggact ggtggcgagg ggctcggtgg cctgtgcttg
     4441 cccgctcagg acccttcagt cacagctcct tcagaagaga ctgcgttctc tggaacctgg
     4501 tgccaccaga ggacagggct ccttctgctc gtctcaggga tggttgacct gcgtggccca
     4561 ggacctcaca ttgctggcgg atggcattct cctgtctcac ctggttgaca agccttgctg
     4621 accccagcca ggacttggct cctcctagtc agcccacact gcctccttgc tgtggactgg
     4681 gctggctttt ctgtcccact gtccactggg aaaggaacgc ttgggtactg ttcttgggaa
     4741 aggacttagg cttgcttgtc ataaggagag gctgtgaggg tgaaagggga caaggtgtgt
     4801 tgggttggag ggtgccagcc agggcttgtg atgagttcct gctccttttc atttctgtgt
     4861 attggccgaa tgaattgcaa gactaacaga cgtctacagt acagtacctg tatcacaagt
     4921 aataacaaaa taaagcctga tgctttgttt ctataaaaaa aaaaaaaaaa aaaaaaaaa
//
