LOCUS       NM_001161362            6938 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus protein phosphatase 2, regulatory subunit B'', alpha
            (Ppp2r3a), transcript variant 1, mRNA.
ACCESSION   NM_001161362 XM_001474396 XM_001475836
VERSION     NM_001161362.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6938)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6938)
  AUTHORS   Koss,M., Bolze,A., Brendolan,A., Saggese,M., Capellini,T.D.,
            Bojilova,E., Boisson,B., Prall,O.W., Elliott,D.A., Solloway,M.,
            Lenti,E., Hidaka,C., Chang,C.P., Mahlaoui,N., Harvey,R.P.,
            Casanova,J.L. and Selleri,L.
  TITLE     Congenital asplenia in mice and humans with mutations in a
            Pbx/Nkx2-5/p15 module
  JOURNAL   Dev Cell 22 (5), 913-926 (2012)
   PUBMED   22560297
REFERENCE   3  (bases 1 to 6938)
  AUTHORS   Zwaenepoel,K., Louis,J.V., Goris,J. and Janssens,V.
  TITLE     Diversity in genomic organisation, developmental regulation and
            distribution of the murine PR72/B' subunits of protein phosphatase
            2A
  JOURNAL   BMC Genomics 9, 393 (2008)
   PUBMED   18715506
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ100577.1, AK042943.1, AK076163.1, AK132175.1, BU758090.1 and
            CX220062.1.
            
            On May 5, 2010 this sequence version replaced NM_001161362.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR10223970.11772.1,
                                           SRR10223971.9610.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-212               CJ100577.1         2-213
            213-2457            AK042943.1         177-2421
            2458-3925           AK076163.1         1510-2977
            3926-6620           AK132175.1         1767-4461
            6621-6807           BU758090.1         18-204              c
            6808-6938           CX220062.1         205-335
FEATURES             Location/Qualifiers
     source          1..6938
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 53.19 cM"
     gene            1..6938
                     /gene="Ppp2r3a"
                     /gene_synonym="3222402P14Rik; A730042E07; C530025M11Rik"
                     /note="protein phosphatase 2, regulatory subunit B'',
                     alpha"
                     /db_xref="GeneID:235542"
                     /db_xref="MGI:MGI:2442104"
     exon            1..171
                     /gene="Ppp2r3a"
                     /gene_synonym="3222402P14Rik; A730042E07; C530025M11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            172..2603
                     /gene="Ppp2r3a"
                     /gene_synonym="3222402P14Rik; A730042E07; C530025M11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2604..2870
                     /gene="Ppp2r3a"
                     /gene_synonym="3222402P14Rik; A730042E07; C530025M11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2871..2974
                     /gene="Ppp2r3a"
                     /gene_synonym="3222402P14Rik; A730042E07; C530025M11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2975..3077
                     /gene="Ppp2r3a"
                     /gene_synonym="3222402P14Rik; A730042E07; C530025M11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3078..3152
                     /gene="Ppp2r3a"
                     /gene_synonym="3222402P14Rik; A730042E07; C530025M11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3153..3239
                     /gene="Ppp2r3a"
                     /gene_synonym="3222402P14Rik; A730042E07; C530025M11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3240..3396
                     /gene="Ppp2r3a"
                     /gene_synonym="3222402P14Rik; A730042E07; C530025M11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3397..3445
                     /gene="Ppp2r3a"
                     /gene_synonym="3222402P14Rik; A730042E07; C530025M11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3446..3535
                     /gene="Ppp2r3a"
                     /gene_synonym="3222402P14Rik; A730042E07; C530025M11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3536..3711
                     /gene="Ppp2r3a"
                     /gene_synonym="3222402P14Rik; A730042E07; C530025M11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3712..3830
                     /gene="Ppp2r3a"
                     /gene_synonym="3222402P14Rik; A730042E07; C530025M11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3831..3937
                     /gene="Ppp2r3a"
                     /gene_synonym="3222402P14Rik; A730042E07; C530025M11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3938..6918
                     /gene="Ppp2r3a"
                     /gene_synonym="3222402P14Rik; A730042E07; C530025M11Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6596..6601
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ppp2r3a"
                     /gene_synonym="3222402P14Rik; A730042E07; C530025M11Rik"
                     /note="hexamer: AATAAA"
     polyA_site      6621
                     /gene="Ppp2r3a"
                     /gene_synonym="3222402P14Rik; A730042E07; C530025M11Rik"
                     /note="major polyA site"
     regulatory      6782..6787
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ppp2r3a"
                     /gene_synonym="3222402P14Rik; A730042E07; C530025M11Rik"
                     /note="hexamer: AATAAA"
     polyA_site      6807
                     /gene="Ppp2r3a"
                     /gene_synonym="3222402P14Rik; A730042E07; C530025M11Rik"
     regulatory      6892..6897
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ppp2r3a"
                     /gene_synonym="3222402P14Rik; A730042E07; C530025M11Rik"
                     /note="hexamer: TATAAA"
     polyA_site      6918
                     /gene="Ppp2r3a"
                     /gene_synonym="3222402P14Rik; A730042E07; C530025M11Rik"
ORIGIN      
        1 ggcgctggcg ggcagctaag ctgctgggcg gctgggcggg gcgcgctcag gcctcggctc
       61 ctcacgcgcg gcgtaagcgg cccagacccc gcgctgcggg aagccggggt ggcgtgtgcg
      121 cgtcgcctgc gagccgaggc agccgcggga ggaggagcag cgggcactga ggtttctctg
      181 tcgcccacca aaaaaaaaaa aaaaaaaaaa aatggatcac ttaaggcctg ggaggactca
      241 gttatcacag taatcctgta ccatcaacta aggtttatct gacagtttat agaaccattg
      301 aagagttaaa agaagatatt ctttcataga acgagtccta tagtatcatg ttactaaata
      361 aaactaaaat gtacaatatt taagttatta gacttgctaa tacaagcata catgtgcaac
      421 agctactgga tactgatagc tatcaaacct caaatttaaa gattttcctt catggaaaag
      481 ttactatact ttgcaagaaa ccactgaacg ttgtcattgg atattttttc agcaaagtat
      541 catttagaaa aaattttctt gaaacaaagt ctataaagtt ctaagtccta ccattgagtg
      601 aatttgatat tatggcagca acttacagac ttgtggttag cactgtgaac cattatagca
      661 gtgtagtgat agaccggcgc tttgaacaag ccatacatta ttgcactgga acctgccata
      721 ccttcacaca tggaatagac tgcattgtgg tgcatcatag tgtctgtgca gatctcgtgc
      781 atatccctgt gtctcagttc aaagatgtgg atctgaactc ggtgtttttg tctcatgaaa
      841 atgggctttc ctcggctgaa gattatcccc atcaagccct cacaggcctg cccaggggca
      901 agaaagcatc tacatttcag aatacctgta acttaaagga cattgcagga gaagcaatta
      961 gctttgccag tgggaaaata aaagaatttt cccttgaaaa actcagaaat tcaaaccatg
     1021 cagcttacag aaaaggaaga aaagttaaat ctgactcatt taataggagg tcagttgatt
     1081 ttgacttact ctgtggccat tataataatg atggaacctc tccacccttt ggtttactcc
     1141 ggagttcctc agttgaggaa aaatctttat ctcacagaaa ttcattagat acaaacctga
     1201 cttccatgct ttttcagaac ttgtctgaag aagatctagt tacacagatt ttagaaaaac
     1261 ataaaataga tcatttttct tctgggacag acataaaaat gtgcttggac atcttactga
     1321 aatgctctga agatttgaaa aaatgcacag acatcataaa acaatgcata aagaaaaagt
     1381 cgggaggtag tatcagtgag ggaagtggca atgaggtgat ttctaactcc gaaactgtct
     1441 atatgaatgt aatgaccagg ttagcttact acctgagaaa gttaccattt gaatttatgc
     1501 agtctgggaa taacgagacc gtagatttga cagaacttat caataatata cctaacttac
     1561 agctgactcc attctcccca ttatatggga ctgaacagcc ccctaaatat gaagatattg
     1621 tccacctctc agccctcgac tccggacagt ttcagactgt tgaattgcaa gatgacaagc
     1681 ataattttaa acaaacagac attgtaaaaa ccactccaaa caacacagat tccttgtgta
     1741 gcttggaggt aaacgatcct ggaactctaa aacctgtgca gcttcagtca ccgttattaa
     1801 ccataaacca tttagagaat gtttcttctg gtaacttaat ggaaactctt tatattgaag
     1861 aggagtcaga cgggaagaag tcattattag ataaagaaca aaaagcagag aatggacaag
     1921 gtcaggaacc attacaggta aatgaacata aagaattttc agaccatgat acttatctta
     1981 aaaaatgtcc tgtctcaatg caaaatgaaa ttggtaagat atttgaaaag ccaataatgg
     2041 ttcatccatc taaggaagat tctaaattag aagttcctac cacagatctc agagaccaga
     2101 ggcactttgt gaatcctaac agtcaggaag agatagacaa attattaatg gatttggaat
     2161 cattctcaca gaagatggag acctctctag gagaaccact tgccaagggt aaaagcatca
     2221 attctctcaa tagtcatagt catttgactg ctcagagcca caaagacctt gagcctaaac
     2281 ctatagcctc ttcagctatg gaaaaagttt caccttcttg tctaacaagg attattgaaa
     2341 acaatggaca caaaatggag gaggaagacc gagccctctt acttcgaatt atggaaagca
     2401 ttgaagactt tgctcaagag ctagttgaat gcaagtcagg cagagggagc ctatcacaag
     2461 aaaaggaaat gatgcaaatt ctacaggaaa ccttgacaac ttcctcccag cccactccat
     2521 cagtctgtag gagccctgtt ggtgagaaac ccaaagatag tacttcagtt gttttgattc
     2581 agcagacgcc agaagtgatc aagattcaaa ataaaccaga aaagaaacct gcaacatcat
     2641 ttccacctgc agccaccctt ccaagtagtc cccagccggc ctcccctgtt ccttgtgtga
     2701 gtgatgtcgt gaatacaccg ttgtccataa acattccaca gttctatttc cctgaaggac
     2761 tcccagacac ctgcagtaac catgaacaga tcctaagcag aattgaaact gctttcaagg
     2821 atattgaaga tcagaaagca gatattcatg aaatggggag aattgcaaag gtctgtggct
     2881 gtccactcta ttggaaagcc cccatgttca gggctgcagg aggagagaag actggatttg
     2941 tgacagcaca gtcattcatt gccatgtgga aaaagttgct aagtaaccgt catgacgatg
     3001 ctgccaagtt catctggctt ctggcaaagc ccagctgcag ctatctagaa caagaggatt
     3061 ttatcccttt acttcaggat gtggtagata cccaccctgg cctcaccttc ctgaaagatg
     3121 ctccagaatt ccattcccgc tacatcacca cggttgttca gagaatattc tacacagtca
     3181 acagatcttg gagtggaaaa attacttcaa cagagataag aaaaagcaac tttttgcaaa
     3241 ctctggccct tttggaggaa gaggaagata taaaccaaat cacagattac ttctcttatg
     3301 aacatttcta tgtcatttat tgtaaattct gggaactaga tggtgatcat gacttgtaca
     3361 tcagtcaagc tgatctgtct cgatacaatg accaggcttc atcaaataga attattgaaa
     3421 gaatattttc tggagcagta acaagaggaa aaactgtaca aaaagaggga agaatgagct
     3481 atgcagattt tgtttggttt ttgatttctg aggaagacaa acggaaccct accagcattg
     3541 agtactggtt ccgctgcatg gatgtggatg gagatggcat actttccatg tatgaactag
     3601 agtacttcta tgaagagcag tgtgaacgga tggaagccat gggcattgag cccttgccgt
     3661 tccatgatct gttgtgccag atgcttgact tggtgaagcc agctagtgat ggcagaataa
     3721 ctctgcgcga tctgaagagg tgcagaatgg cccacatctt ctacgacact ttctttaacc
     3781 tggagaaata cttggaccat gaacaaagag atccttttgc agtccagaag gatgttgaaa
     3841 atgatggccc tgagccatct gactgggaca gatttgcggc tgaggagtac gaggctctcg
     3901 taactgagga gtctgcccag gttcagctcc aagaaggctc atttgaagac tatgaatcag
     3961 atgaacctgt atctccctct gaacttggaa acaagggcaa taaaatagta acttcaagcc
     4021 tttcagagaa atgtggaaag cttcagtcag tggatgaaga gtagttacca ttatctacac
     4081 cagaaggatg ctgtgtagag atgctctagt ttgtacactg ctttgtaaag ggtttgattc
     4141 ctccatgtgc actagaaact aagatgctct aagtagttca gcacaggaga cccctccagt
     4201 ttgtggaaaa tgtgcagagc tcgtccttgg aagtagcata ctgtcaccag tcaccttcca
     4261 aacaaagtct gcagtcagcg ctgcccccct cagtgcatgg aggctctctt ggaaccaagg
     4321 tcacacgtga cacacagttc tctgcacagt agcagaagct gccttgcttg gtactgccag
     4381 cttccctggg gtactgcagg ctcctacaga acctggaaga aaacctcact tgagtcaaaa
     4441 attctggaac ttgaaaaagg gcctctagaa ctggctttgt cccagtaaca aaagcactgc
     4501 caaaacatct cagaaactac ttctatgtac tggagttcag ggaccttgaa cttacctggt
     4561 ttaatgtaat ttcaccatga cctgccaaac tgctaagtca ctttacattc tcaggtatta
     4621 taaccactgg gcccttccag ctctgctggc aagctctggc agcctctgca tctgactgtg
     4681 gaccttgtac aaaaatctca tgaaaacatt tctgaaaatg aagacaatta cagaatttgg
     4741 cacttattaa catttgcaga taattattgg ataatgtact aatctacaaa tcaatgacct
     4801 atcttcattt ctagcagaag gcttacttga agacttagga atgggacatc ccatggaaac
     4861 ctctcactat acacactccg tcccctctct tgaatactag actaagtcaa aagtaaaagg
     4921 cacaaactac acagtgttcc ttacttcctg tggaaaacac ctaccacatc aggtatttca
     4981 tccaccttat tattatcaac cttggaagaa aaacgattat tctcacccac agtagaaaag
     5041 ccttttacta tagtggtaaa ttcagaattc tatacttttc aatggccacg cagccaaccc
     5101 ctacaatatg cttgttgtta cccttcatgc tgaaaaaaga gaaggaaaaa aaaaactaaa
     5161 aagaatggac atgtctaaaa tcagagtgac tctttttccc aactttaaag ggtcagagta
     5221 gccacccttc ctctccatcc tagttttctt cctaattgaa aggccacgca gtgaaataat
     5281 caaaccttgg gagatagaat aagaaatgta atatcaacta atactagaaa ttagcaagcc
     5341 ctgcaacccc acccgtccca agattctcca gttccctaag actcaactaa tcttccttat
     5401 acccatcata gaaactggga actattacaa ctaggagtta accccgataa ttaaaaccta
     5461 acagtgacta aactgaggga aaaaatttac aaaagatctc acacatttgg tggcacatgc
     5521 ctaaaatctc cggatttagg tagttaaggc aggagacgag agaatgcaca tctatattac
     5581 cccagataca ctgcttgctg taatgccggg gctcagcagc ctggggtgag gagggctcat
     5641 agtttgaggt cagcatggac tacacagtga aaccttgtct taaaaagaat tatatgatgt
     5701 tgctgccaat cccatccaag tttagtagga agagggaatg atttaatttc aaacgaaaat
     5761 gcaaaagggt aatagttatt aaaggggtgg gggtagaggt ataaagaatt ttattagctg
     5821 ggtatctaaa gtattttgag acttacccag aagcacagaa ctcagctcta taatatcctt
     5881 taaacaacag gagcacaggg ctgagccggt taaacctcac caactgcact gaaatgtatg
     5941 caactcgtac tttgtggtgc tgggaatcaa aacctggacg atccacaggc caagaaagcg
     6001 ctgcaccacc gctgcacctc agcccttttt cattattctg ttaccttgtt cctccaccct
     6061 tactcgactc tgctttttac cttgatcaaa acccatcaac accatccagt tggaggacta
     6121 tttaatttgg gttacctgaa ttatactttc tttataaaca agtgtttcac cctattcctt
     6181 tcttagaaat gaatgcaagg agtgcaactt ctaaggaact aggttagtat gtatttgatg
     6241 ttctggtaaa gatgaagcta agtatactcc ttactaacaa actggaaatg tcaagttgtg
     6301 acgatacccc cagggacctt ggaaaagatg aactataatc taaagcagcg gttctcaaca
     6361 ctcctaatgc tgtgaccctt taatacagtt cctcacgtta tggtgacccc caaccataaa
     6421 attatttgct acttcataaa tgtaatttta ctattattaa tcatgatgta aatagccgat
     6481 atgtgttacg caacccctgt gaaaggggtt tcgaccccca ggttgagaac cactaatcta
     6541 aatattattt aatgaaagga gggtttcata gcataattgt caaggtaatc aaactaataa
     6601 aattctgtat atttccctgc atctatcata tctgttactg ttcaaaatgt tgggttttgt
     6661 tgttttttta aaagggaaag aaaaggaaga aagaaaaccc cagcactagc gcagatatcc
     6721 tgtgtggcgc tggccgagcg gagtagacgg tgcatgagtt gttctcccct ctgccaaaca
     6781 aaataaagct gtctgtcgtg tgctcgactg cgttcactct gcagtgcggt ttagatacaa
     6841 ttcggcttta tgcctgcaag tgcagctgag gttttgaaga cttggggatg ttataaagaa
     6901 ctcttaatgc aatctaaaaa aaaaaaaaaa aaaaaaaa
//
