LOCUS       NM_029628               2320 bp    mRNA    linear   ROD 19-SEP-2024
DEFINITION  Mus musculus protein phosphatase 1, regulatory subunit 3G
            (Ppp1r3g), mRNA.
ACCESSION   NM_029628 XM_127272 XM_911525
VERSION     NM_029628.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2320)
  AUTHORS   Du,J., Xiang,Y., Liu,H., Liu,S., Kumar,A., Xing,C. and Wang,Z.
  TITLE     RIPK1 dephosphorylation and kinase activation by PPP1R3G/PP1gamma
            promote apoptosis and necroptosis
  JOURNAL   Nat Commun 12 (1), 7067 (2021)
   PUBMED   34862394
  REMARK    GeneRIF: RIPK1 dephosphorylation and kinase activation by
            PPP1R3G/PP1gamma promote apoptosis and necroptosis.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2320)
  AUTHORS   Yorgan,T.A., Peters,S., Amling,M. and Schinke,T.
  TITLE     Osteoblast-specific expression of Panx3 is dispensable for
            postnatal bone remodeling
  JOURNAL   Bone 127, 155-163 (2019)
   PUBMED   31202927
REFERENCE   3  (bases 1 to 2320)
  AUTHORS   Li,Q., Zhao,Q., Zhang,J., Zhou,L., Zhang,W., Chua,B., Chen,Y.,
            Xu,L. and Li,P.
  TITLE     The Protein Phosphatase 1 Complex Is a Direct Target of AKT that
            Links Insulin Signaling to Hepatic Glycogen Deposition
  JOURNAL   Cell Rep 28 (13), 3406-3422 (2019)
   PUBMED   31553910
REFERENCE   4  (bases 1 to 2320)
  AUTHORS   Zhang,Y., Gu,J., Wang,L., Zhao,Z., Pan,Y. and Chen,Y.
  TITLE     Ablation of PPP1R3G reduces glycogen deposition and mitigates
            high-fat diet induced obesity
  JOURNAL   Mol Cell Endocrinol 439, 133-140 (2017)
   PUBMED   27815211
  REMARK    GeneRIF: PPP1R3G is an important player that links glycogen
            metabolism to lipid metabolism in vivo.
REFERENCE   5  (bases 1 to 2320)
  AUTHORS   Zhang,Y., Xu,D., Huang,H., Chen,S., Wang,L., Zhu,L., Jiang,X.,
            Ruan,X., Luo,X., Cao,P., Liu,W., Pan,Y., Wang,Z. and Chen,Y.
  TITLE     Regulation of glucose homeostasis and lipid metabolism by
            PPP1R3G-mediated hepatic glycogenesis
  JOURNAL   Mol Endocrinol 28 (1), 116-126 (2014)
   PUBMED   24264575
  REMARK    GeneRIF: PPP1R3G plays a critical role in postprandial glucose
            homeostasis and liver triglyceride metabolism via its regulation on
            hepatic glycogenesis.
REFERENCE   6  (bases 1 to 2320)
  AUTHORS   Luo,X., Zhang,Y., Ruan,X., Jiang,X., Zhu,L., Wang,X., Ding,Q.,
            Liu,W., Pan,Y., Wang,Z. and Chen,Y.
  TITLE     Fasting-induced protein phosphatase 1 regulatory subunit
            contributes to postprandial blood glucose homeostasis via
            regulation of hepatic glycogenesis
  JOURNAL   Diabetes 60 (5), 1435-1445 (2011)
   PUBMED   21471512
  REMARK    GeneRIF: PPP1R3G plays a major role to control postprandial glucose
            homeostasis during the fasting-feeding transition via its
            regulation on liver glycogenesis.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ158734.1, AK079637.1, AK005570.1 and BQ031560.1.
            
            On or before Feb 12, 2009 this sequence version replaced
            XM_911525.3, XM_127272.7.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CJ158734.1, AK079637.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-30                CJ158734.1         1-30
            31-1311             AK079637.1         2-1282
            1312-2119           AK005570.1         622-1429
            2120-2320           BQ031560.1         1-201               c
FEATURES             Location/Qualifiers
     source          1..2320
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 14.44 cM"
     gene            1..2320
                     /gene="Ppp1r3g"
                     /gene_synonym="1600032L17Rik"
                     /note="protein phosphatase 1, regulatory subunit 3G"
                     /db_xref="GeneID:76487"
                     /db_xref="MGI:MGI:1923737"
     exon            1..77
                     /gene="Ppp1r3g"
                     /gene_synonym="1600032L17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            78..2308
                     /gene="Ppp1r3g"
                     /gene_synonym="1600032L17Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             519..1562
                     /gene="Ppp1r3g"
                     /gene_synonym="1600032L17Rik"
                     /note="putative protein phosphatase 1 regulatory inhibitor
                     subunit 3G; protein phosphatase 1, regulatory (inhibitor)
                     subunit 3G"
                     /codon_start=1
                     /product="protein phosphatase 1 regulatory subunit 3G"
                     /protein_id="NP_083904.1"
                     /db_xref="CCDS:CCDS49237.1"
                     /db_xref="GeneID:76487"
                     /db_xref="MGI:MGI:1923737"
                     /translation="MDPSGEQLHRSEASSSTSSGDPQSAEELSVPEVLCVESGTSETP
                     IPDAQLQDRPLSPQKGAALPEQEELQEYRRSRARSFSLPADPILQAAKLLQQRQQAGQ
                     PSSEGGAPAGDCCSKCKKRVQFADSLGLSLASVKHFSEAEEPQVPPAVLSRLHSFPLR
                     AEDLQQLGGLLAVATMPDPLLVPCARLRPHFQLPELRAAEERLRRQRVCLERVQCSQP
                     PRAEVTGSGRVISCPGPRAVAVRYTFTEWRTFLDVPAELDPESVEPLPPLQSGDSGSK
                     AEDSEEGPGTERFHFSLCLPPGLQPKEGEDAGAWGVAIHFAVCYRCEQGEYWDNNEGA
                     NYTLRYVCSTDPL"
     regulatory      2099..2104
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ppp1r3g"
                     /gene_synonym="1600032L17Rik"
                     /note="hexamer: AGTAAA"
     polyA_site      2119
                     /gene="Ppp1r3g"
                     /gene_synonym="1600032L17Rik"
                     /note="major polyA site"
ORIGIN      
        1 tcttgtctgc ctgcctagtg agctcccggt gggttcctgc tctgtcccct gctcaagcgc
       61 agcagcaagg tcaccaggcc agtgacagcc aggacgtctc ctccggaaga ataacttcac
      121 aggctggaaa actttgtcta gttctgaaag ttgagagcta ccccagagga tacagacgcg
      181 catagcagcc gcggggtgga tcaaagctat cggctagcct acgaccttca gaaatcctag
      241 tctccactac ggacgtagct ctcaggtgtt ctggctgtcg cgcctccctg tcttggccct
      301 ccccttggga gctagccgca ggccagcatc ctcctccctc ttggtcccgg gcagcagcag
      361 ctaaaagctg gaggttccag gccgaatccg ctttctgcca gggtaggcaa gcccagccga
      421 cactatgcgc tccttctgct gcgggagtag ataaaagttt ccagaggact ctccgcggtt
      481 cccgcaggac gaaacccggg gccggatcgg acactgtcat ggatccctcg ggagaacagc
      541 tacacagatc cgaggcgtcc agctctacgt cttccggaga ccctcaatcc gcggaggaac
      601 tgtcggtccc cgaggtcctt tgcgtggaga gtggcacctc tgagaccccg atccctgatg
      661 ctcagctcca ggaccggccc ctgtcgccgc agaaaggggc agctctcccg gaacaggagg
      721 agctacagga atatcgccgc tctcgtgcgc gctccttctc tttgcccgca gaccccatcc
      781 tgcaggcggc caagctcctg cagcagaggc agcaggcggg acagcccagc tcagagggtg
      841 gcgcgccggc tggggactgc tgctccaagt gtaagaagcg cgtgcagttc gccgactccc
      901 tgggactgag cctggccagc gtgaagcact tcagcgaggc cgaggagcct caggtgcccc
      961 cggccgtact ttcccgtctc cacagcttcc cgctgcgcgc cgaggacctg cagcagctcg
     1021 gggggctgct ggcagtggca acgatgcctg atcctctctt ggtaccctgc gcccggctcc
     1081 gaccccactt ccagctcccg gagctgcgcg ctgcggagga gcgtctgcgg cgacagcgag
     1141 tgtgcctgga gcgtgtgcag tgctcccagc cgccccgcgc cgaggtgacc ggctctggcc
     1201 gagtgatcag ttgccccgga cccagggcag tggcggtgcg ctacactttc acggagtggc
     1261 gtacctttct ggacgtgcct gctgagctgg acccggagtc agtggagccc ctgcctccat
     1321 tgcagtcagg ggactctgga tcaaaggctg aggatagtga ggaggggccc ggcaccgagc
     1381 gtttccactt ctcgctgtgc ctgcccccgg gtctgcagcc caaagaaggg gaggatgctg
     1441 gcgcgtgggg agtcgctatt cattttgccg tctgctaccg ctgcgaacag ggagaatact
     1501 gggacaacaa cgagggggcc aactacacct tgcgctatgt gtgctccaca gacccgctct
     1561 gagtccggga acttcggaac ttggaaagag gttgaccagc tagcaagggc tccccgggga
     1621 tccttagctg agcaacgcat tgacagagcg tggagcgata ggagtaaaat gttaaaccat
     1681 acactctcag cgcagattca cggcaagctc tggcagtgtt ctcagtgttt ttctcatcac
     1741 ttccactgac ctttctactc gcctcttaga attctcagcc tgcatccaaa taaggaacat
     1801 cctcgtttcc cagggagagg ctctctccaa gaaaagggct ctgggaccct gaaccttggg
     1861 gatttgtttc taacttgaga cttggtcctt acaccttgat gaaaacctgc aggagaaaga
     1921 catggcagcc cacctccacg tgggagaaga aggccttcac acgtggaagc ttcacagcca
     1981 ggcttgattt tcagaaggct aggagggcgt cagcttgtcc ttttaactgg gctctggaaa
     2041 cacctcccca gattcgatgt attttcttcc gtgattggat acaaatgtct tttaagaaag
     2101 taaaggccgc gtgaacatgt gtcctctctg tgtttcatgt tttaccttcc gaggttttgg
     2161 ggagtccgtg gcagtcagag gatgctcggc tgatgacacg gcagtgtgac aattatgaaa
     2221 caacagtatt aacacatttt ctcatgacgt ggaatagtcc aagttcccca cactgggaat
     2281 aaaaatcttc aaaatgtttt gtaaaaagaa aaaaaaaaaa
//
