LOCUS       NM_001407865            5909 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus diphosphoinositol pentakisphosphate kinase 1
            (Ppip5k1), transcript variant 2, mRNA.
ACCESSION   NM_001407865
VERSION     NM_001407865.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5909)
  AUTHORS   Khaled,M.L., Bykhovskaya,Y., Gu,C., Liu,A., Drewry,M.D., Chen,Z.,
            Mysona,B.A., Parker,E., McNabb,R.P., Yu,H., Lu,X., Wang,J., Li,X.,
            Al-Muammar,A., Rotter,J.I., Porter,L.F., Estes,A., Watsky,M.A.,
            Smith,S.B., Xu,H., Abu-Amero,K.K., Kuo,A., Shears,S.B.,
            Rabinowitz,Y.S. and Liu,Y.
  TITLE     PPIP5K2 and PCSK1 are Candidate Genetic Contributors to Familial
            Keratoconus
  JOURNAL   Sci Rep 9 (1), 19406 (2019)
   PUBMED   31852976
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5909)
  AUTHORS   Inoue,S.I., Takahara,S., Yoshikawa,T., Niihori,T., Yanai,K.,
            Matsubara,Y. and Aoki,Y.
  TITLE     Activated Braf induces esophageal dilation and gastric epithelial
            hyperplasia in mice
  JOURNAL   Hum Mol Genet 26 (23), 4715-4727 (2017)
   PUBMED   28973166
REFERENCE   3  (bases 1 to 5909)
  AUTHORS   Fridy,P.C., Otto,J.C., Dollins,D.E. and York,J.D.
  TITLE     Cloning and characterization of two human VIP1-like inositol
            hexakisphosphate and diphosphoinositol pentakisphosphate kinases
  JOURNAL   J Biol Chem 282 (42), 30754-30762 (2007)
   PUBMED   17690096
REFERENCE   4  (bases 1 to 5909)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   5  (bases 1 to 5909)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   6  (bases 1 to 5909)
  AUTHORS   Nishiguchi,S., Sakuma,R., Nomura,M., Zou,Z., Jearanaisilavong,J.,
            Joh,T., Yasunaga,T. and Shimada,K.
  TITLE     A catalogue of genes in mouse embryonal carcinoma F9 cells
            identified with expressed sequence tags
  JOURNAL   J Biochem 119 (4), 749-767 (1996)
   PUBMED   8743579
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL845466.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17253011.8374910.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-36                AL845466.4         61952-61987         c
            37-228              AL845466.4         57934-58125         c
            229-325             AL845466.4         57568-57664         c
            326-500             AL845466.4         57128-57302         c
            501-696             AL845466.4         56598-56793         c
            697-787             AL845466.4         56126-56216         c
            788-873             AL845466.4         55825-55910         c
            874-1028            AL845466.4         55345-55499         c
            1029-1130           AL845466.4         55118-55219         c
            1131-1292           AL845466.4         54132-54293         c
            1293-1414           AL845466.4         53915-54036         c
            1415-1516           AL845466.4         50127-50228         c
            1517-1603           AL845466.4         49790-49876         c
            1604-1679           AL845466.4         49612-49687         c
            1680-1789           AL845466.4         49406-49515         c
            1790-1872           AL845466.4         49228-49310         c
            1873-2004           AL845466.4         48556-48687         c
            2005-2126           AL845466.4         48267-48388         c
            2127-2309           AL845466.4         47402-47584         c
            2310-2451           AL845466.4         44473-44614         c
            2452-2675           AL845466.4         44100-44323         c
            2676-2803           AL845466.4         43734-43861         c
            2804-2918           AL845466.4         43377-43491         c
            2919-3026           AL845466.4         43047-43154         c
            3027-3140           AL845466.4         41374-41487         c
            3141-3305           AL845466.4         41064-41228         c
            3306-3455           AL845466.4         38893-39042         c
            3456-3546           AL845466.4         38209-38299         c
            3547-3672           AL845466.4         34296-34421         c
            3673-3735           AL845466.4         33503-33565         c
            3736-3873           AL845466.4         28306-28443         c
            3874-3987           AL845466.4         23306-23419         c
            3988-5909           AL845466.4         17212-19133         c
FEATURES             Location/Qualifiers
     source          1..5909
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 60.37 cM"
     gene            1..5909
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /note="diphosphoinositol pentakisphosphate kinase 1"
                     /db_xref="GeneID:327655"
                     /db_xref="MGI:MGI:2443281"
     exon            1..36
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            37..228
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            229..325
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            326..500
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     CDS             354..4814
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /EC_number="2.7.4.24"
                     /note="isoform 1 is encoded by transcript variant 2;
                     inositol hexakisphosphate and
                     diphosphoinositol-pentakisphosphate kinase 1; VIP1
                     homolog; insP6 and PP-IP5 kinase 1; histidine acid
                     phosphatase domain-containing protein 2A; histidine acid
                     phosphatase domain containing 2A"
                     /codon_start=1
                     /product="inositol hexakisphosphate and
                     diphosphoinositol-pentakisphosphate kinase 1 isoform 1"
                     /protein_id="NP_001394794.1"
                     /db_xref="GeneID:327655"
                     /db_xref="MGI:MGI:2443281"
                     /translation="MWSLTANEDESTTAHFFLGAGDEGLGTCGIGMRTEESDSELLED
                     EEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENW
                     PSCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLP
                     RYAVLNRDPACPEECSLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGG
                     SQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSP
                     ALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVN
                     GFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELR
                     CVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRL
                     LLAELEKEPEAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGVKASNEGQDL
                     QREPLAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHS
                     TFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSL
                     SSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALI
                     ENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYD
                     CVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKI
                     LLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDE
                     TQDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEE
                     GSAPAGCGFRPASSENEEMKTDPGSIENLCPGKASDEPDRALQTSPQPVEGTGLPRRS
                     PLIRNRKAGSMEVMNMQCTGNLDLIPLRGRRRRRSGDLPRLSPAISLQPRAVSTTHLA
                     SCTQVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQD
                     YARTHGKKLPPASLKHRDELLFVPAVKRFSVSFAKHPTNGFEGCSMVPTIYPLETLHN
                     ALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHNHQASDSPFSPPRTLHSPPLQLRH
                     RSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSHFGFSDQSSVNIHMTEEKQGFGLLQET
                     PGDGTRELHIERQQELVEPAQSPQELPVEICPSGSQGVTKVSQTCQEVPDIVQPCHNI
                     HEEIGQPQQEVPDISQLLLKDHDTTTNTCHLCQASQLSQKVCEEICQLCQDNHEESNQ
                     LCQEVSVKLGRMVHGFPVNVDSTAQETLMEIGRPTQEIPEDPYQEFSVKVGVLAQKAP
                     AISELSQDIPEADKPSQELSEETELQAQEVSEEIDQESEVVDELPPEAIS"
     exon            501..696
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            697..787
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            788..873
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            874..1028
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            1029..1130
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            1131..1292
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            1293..1414
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            1415..1516
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            1517..1603
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            1604..1679
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            1680..1789
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            1790..1872
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            1873..2004
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            2005..2126
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            2127..2309
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            2310..2451
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            2452..2675
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            2676..2803
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            2804..2918
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            2919..3026
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            3027..3140
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            3141..3305
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            3306..3455
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            3456..3546
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            3547..3672
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            3673..3735
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            3736..3873
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            3874..3987
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     exon            3988..5909
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5888..5893
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /note="hexamer: AATAAA"
     polyA_site      5909
                     /gene="Ppip5k1"
                     /gene_synonym="B430315C20Rik; Hisppd2a; mKIAA0377"
                     /note="major polyA site"
ORIGIN      
        1 gccggcaggt tcggctgcgc gagcggaggg aggcggctgc tgctatggag gaccttgtcc
       61 tagaccagca ttggtttggc agtcctagag gacagtgaat ggaccattga gatttcaatt
      121 tgagaatgga ttgaaaactg ctttgtggat ggttatctca accccccaac cagcaccaga
      181 cttctttcct tgaactgatt ctgtgaattt ggatatctgt ctgttaagga accaacagta
      241 gccttcctgg aagaactgcc tcttctcctt gctgcctgga gttaacattg tttcctgctg
      301 gcagaatcag tgacatgcca gcactagcgg gatgagtggg tgttccggcg gggatgtggt
      361 ccttgacggc caatgaggac gagagcacta cggcccactt cttccttgga gctggagatg
      421 aggggttggg cacctgtgga ataggcatga ggacagaaga gagtgacagt gaactccttg
      481 aggacgagga ggatgaggtg cccccagaac ctcaaattat tgttggcatc tgtgccatga
      541 ccaagaaatc caagtccaag ccaatgaccc aaattctaga gcgactctgc agatttgact
      601 acctgaccgt tgtcatcctg ggagaagatg tgatcctaaa tgaacctgtg gagaactggc
      661 cgtcctgcca ctgcctcatc tctttccact ccaaaggctt tcctctcgac aaagctgtgg
      721 cttactccaa gcttcgaaac cccttcctta tcaatgactt ggccatgcag tattacatcc
      781 aagataggag ggaggtgtac cggatcctac aggaggaagg tattgatctg ccaagatatg
      841 ctgtcctcaa ccgtgacccc gcctgtcctg aggagtgcag cctgatagaa ggtgaagacc
      901 aggtggaggt taatggagct gtttttccca agccctttgt ggagaagcca gtgagtgcag
      961 aggaccacaa tgtttacatc tactacccca gctctgctgg aggaggaagc cagcgcctct
     1021 tccgtaagat cggcagccgg agcagcgtgt actctcctga gagcagtgtg cggaagacag
     1081 gatcatacat ctatgaggag ttcatgccga cagatggcac agatgttaag gtgtacacag
     1141 tggggccaga ttatgcccat gctgaagcta gaaagtctcc agctttggat gggaaggttg
     1201 aacgagacag tgaggggaaa gaggttcgat atccagtcat gttgaccgcc atggaaaagc
     1261 tggtggccag gaaggtctgc gtagctttta agcaaacagt ttgtggattt gaccttcttc
     1321 gggccaatgg tcactctttt gtgtgtgacg tcaatggctt tagctttgtc aagaactcga
     1381 tgaagtacta tgatgactgt gccaagattc tggggaacac tattatgcga gagcttgccc
     1441 cgcagttcca gataccgtgg tccatcccca cagaagctga ggacattccc attgtcccta
     1501 ccacatctgg cactatgatg gaactccgtt gtgtcatcgc gatcatccgt catggagata
     1561 gaaccccaaa gcagaagatg aagatggagg tgacgcaccc gaggtttttt gctctatttg
     1621 aaaaacatgg tggatataag acgggaaaat taaaacttaa gcggccggag cagctccagg
     1681 aggtgctgga cattacgagg ctgctgttgg cagagctgga gaaggagcca gaagccgaga
     1741 ttgaggagaa gactgggaag ctcgagcagc tgaagtccgt gctggagatg tatggtcact
     1801 tctcaggtat taatcggaag gtgcagttga cctactaccc ccacggagtg aaagcgtcga
     1861 acgaggggca agatctgcag agagagccac tagcaccctc tctcttgctg gtgctgaagt
     1921 ggggtggaga gctgacaccc gatggccgtg ttcaggctga agagctgggg cgagctttcc
     1981 gctgcatgta tcccggaggc cagggtgact atgccggctt ccccggctgt gggctgcttc
     2041 gcctccatag cactttccgt catgacctca agatctacgc ctctgatgag ggccgcgtcc
     2101 agatgactgc tgctgccttt gcaaagggcc tcttagctct agaaggggag cttacaccca
     2161 ttttggtaca aatggtgaag agtgccaaca tgaatggcct tctggacagt gacagcgact
     2221 ccctaagcag ctgccagcac cgtgtgaagg cgcgactgca ccacattttg cagcaggatg
     2281 caccctttgg ccctgaggac tatgaccagc tggctccaac tggaagcacg tctctgctca
     2341 actccatgtc tgtaatccag aatcccgtga aagtctgtga tcaggtattt gccctgattg
     2401 aaaaccttac ccaccagatt cgggaacgga tgcaagaccc cagctctgta gacctgcagc
     2461 tctaccacag tgagacacta gagctaatgc tacagcgttg gagcaaacta gagcgtgact
     2521 ttcgacaaaa gagcgggcgc tatgatatca gtaagatccc tgatatctat gactgtgtca
     2581 agtatgatgt gcaacacaac gggagtctgg gacttcaagg cacagccgag ttactccgtc
     2641 tttccaaagc tctggctgac gtggtcattc cccaggagta tgggatcagt agagaggaga
     2701 aagtggagat tgctgtgggc ttctgccttc cactgctgcg gaaaatccta cttgacctgc
     2761 agagaactca cgaggatgag tctgtcaaca agctgcatcc cctgtactca cgtggagtgc
     2821 tctccccagg ccgccatgtt cgaactcggc tctatttcac cagtgagagt catgttcact
     2881 ccttactcag tgtcttccgt tatgggggac ttctcgatga gacccaggat gcccagtggc
     2941 agcgagcctt ggcttatctc agtgccatct cagagctgaa ctacatgacc cagattgtta
     3001 tcatgcttta tgaggacaac acgagggacc ccttgtcaga ggagcggttc catgtggagc
     3061 tacatttcag ccctggagtg aaaggagttg aggaaggcag tgccccagcc ggctgtggat
     3121 tccgtccagc ctcatctgag aatgaagaga tgaaaacaga tccaggcagc attgagaacc
     3181 tgtgcccagg gaaggcatcc gatgaaccag accgagcact gcagacctca ccccaacctg
     3241 ttgagggcac tggcctcccg aggagatcac ccctcattcg taatcgaaaa gctggttcca
     3301 tggaggtcat gaacatgcag tgcacgggga acctggacct gatccccttg aggggacggc
     3361 gccgtaggag gtcaggagac ctccccaggc tttccccagc catcagccta cagccccggg
     3421 ctgtgtccac cactcacctg gcttcctgca cacaggtgct gtctgaaact tcatcttcaa
     3481 gacctggtgg ctaccgtctg ttttcatctt cacggccacc aacagagatg aagcagagtg
     3541 gcctaggctc acagtgtaca gggctgttca gcaccacagt gctgggtggc tcctccagtg
     3601 ctccgaatct tcaggactac gcccgcaccc atggcaaaaa gctcccgcct gccagtctaa
     3661 agcaccgaga tgagctcttg tttgtcccgg ccgtaaaacg attttctgtg tcgtttgcaa
     3721 agcatccgac taacggattt gaagggtgct ccatggtacc taccatctac cccctggaga
     3781 cactgcacaa tgccctttcc ttgcgccaag tgagtgaatt cttgactaaa gtctgccagc
     3841 gccacactga tgcccacgca caggcatctg cagccctctt tgactctatg cacaaccatc
     3901 aggcctcaga tagcccgttc tccccacccc gcactcttca ttcgccaccc ctgcaacttc
     3961 ggcatcgctc tgaaaagcca ccttggtaca gcagcgggcc ttccagtact gtgtccagtg
     4021 ctggcccttc ctctcctact acagtagatg gaaactcaca ctttggcttc agtgatcagt
     4081 cctctgtaaa tatacatatg actgaagaaa agcaaggctt tgggttgctc caggagactc
     4141 ctggagatgg aacacgagag ctccatatag aaagacagca agagcttgtt gagccagctc
     4201 agtcccctca agagctacct gtggaaatct gcccttcagg aagtcagggt gttaccaagg
     4261 tcagccagac atgccaggag gtcccggaca tcgtccagcc gtgtcacaac atccatgagg
     4321 agattggcca gcctcagcag gaggtccctg acatcagcca gctgttgctg aaggaccatg
     4381 acactactac caacacgtgc cacctgtgcc aggccagcca gctgtctcag aaagtttgtg
     4441 aggaaatttg ccagctttgt caagacaacc atgaggagag taaccaacta tgccaggaag
     4501 tctcagtaaa gctgggcagg atggtccatg gattccctgt aaatgttgat agcacggccc
     4561 aggaaaccct tatggaaatt ggcagaccaa cccaagagat ccctgaagat ccataccagg
     4621 agttctctgt gaaggttggc gtgctggctc agaaggcccc tgccatcagt gagctatctc
     4681 aagacatccc tgaggctgac aaaccatccc aagagctctc tgaggagact gagctgcagg
     4741 ctcaggaggt ctctgaggag attgatcagg agtctgaggt ggttgatgag ctgcctcctg
     4801 aggctatctc ctaagttcaa tgtctaccca gtgatgtaaa cactgaaaac cagtctctgg
     4861 ccatgaccag cactcacccc tccactagca ccatgtgact tgtagtcttg tcgttggttt
     4921 cccactctgc cagctctttg agccagcagc ctttctgttg gctaacacac agaaagagcc
     4981 ccacgcaagg tgtgggctca cagcagcagt atctgagaaa gcaggccttg tggcatggaa
     5041 cttacttctg ccagcgctta tacttacgga ggagctgttg atgttcagag acattgttgg
     5101 ctcttcactt agccatggag tgggaatcat agattgtttg gaggaaatgc cacttaactg
     5161 ctgaagatac cgtgctgagg gaacagcaga tataacatgg aaggtggcag ggtctcttct
     5221 tgttgactga aatattcaca gctttttagg gtatcctcag tccatatgtg cattcaagga
     5281 aactcttaac ttcactagca caggctagca caggggaacc acctaaaatg tctggaaaat
     5341 agagttccaa tctcaaaaac atctgttgtg gctactcatg gtttatactg agctcatggg
     5401 tgtttccatg taattgccaa gtgctcccct gcctagtcct gcttctgtgg acatcagctc
     5461 aagagaaaaa tagatattag attgccatgc aacttcagag tgactactta gactgctctg
     5521 ggagatttgc atcaatctat gaagccaggc ctccttttgt tgtggggctg ttgggcttag
     5581 aagatgctgt aatagagaga atcaagttct attttaaaca attagcagag atcaatgttg
     5641 tacagatatg agcaaagatt taatatatat atatatatat atatatataa acatatatat
     5701 ttctgtagtt tgccagggac agactggcca aagatcaaac actccagggt ccccaagagg
     5761 tttgtcctta tatcatgtgt ctttatgacc atatgtgatt acaaagcttt tcccaaagat
     5821 ctagggatgg gagtgggtgt gggtaatgtt gtcattggag tctggggccg gaacatgaca
     5881 agtgctcaat aaacacaaaa taatgagaa
//
