LOCUS       NM_026845               1215 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus peptidylprolyl isomerase (cyclophilin)-like 1 (Ppil1),
            mRNA.
ACCESSION   NM_026845 XM_994453 XM_994476
VERSION     NM_026845.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1215)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1215)
  AUTHORS   Chai,G., Webb,A., Li,C., Antaki,D., Lee,S., Breuss,M.W., Lang,N.,
            Stanley,V., Anzenberg,P., Yang,X., Marshall,T., Gaffney,P.,
            Wierenga,K.J., Chung,B.H., Tsang,M.H., Pais,L.S., Lovgren,A.K.,
            VanNoy,G.E., Rehm,H.L., Mirzaa,G., Leon,E., Diaz,J., Neumann,A.,
            Kalverda,A.P., Manfield,I.W., Parry,D.A., Logan,C.V., Johnson,C.A.,
            Bonthron,D.T., Valleley,E.M.A., Issa,M.Y., Abdel-Ghafar,S.F.,
            Abdel-Hamid,M.S., Jennings,P., Zaki,M.S., Sheridan,E. and
            Gleeson,J.G.
  TITLE     Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause
            Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly
  JOURNAL   Neuron 109 (2), 241-256 (2021)
   PUBMED   33220177
  REMARK    GeneRIF: Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause
            Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly.
REFERENCE   3  (bases 1 to 1215)
  AUTHORS   Markiewicz-Potoczny,M., Lobanova,A., Loeb,A.M., Kirak,O.,
            Olbrich,T., Ruiz,S. and Lazzerini Denchi,E.
  TITLE     TRF2-mediated telomere protection is dispensable in pluripotent
            stem cells
  JOURNAL   Nature 589 (7840), 110-115 (2021)
   PUBMED   33239785
REFERENCE   4  (bases 1 to 1215)
  AUTHORS   Cobellis,G., Nicolaus,G., Iovino,M., Romito,A., Marra,E.,
            Barbarisi,M., Sardiello,M., Di Giorgio,F.P., Iovino,N., Zollo,M.,
            Ballabio,A. and Cortese,R.
  TITLE     Tagging genes with cassette-exchange sites
  JOURNAL   Nucleic Acids Res 33 (4), e44 (2005)
   PUBMED   15741177
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1215)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   6  (bases 1 to 1215)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC162182.2.
            
            On Oct 19, 2007 this sequence version replaced NM_026845.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK004331.1, AK156809.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-100               AC162182.2         136238-136337
            101-255             AC162182.2         138318-138472
            256-324             AC162182.2         147891-147959
            325-1215            AC162182.2         148484-149374
FEATURES             Location/Qualifiers
     source          1..1215
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 15.15 cM"
     gene            1..1215
                     /gene="Ppil1"
                     /gene_synonym="1110060O10Rik; Cypl1"
                     /note="peptidylprolyl isomerase (cyclophilin)-like 1"
                     /db_xref="GeneID:68816"
                     /db_xref="MGI:MGI:1916066"
     exon            1..100
                     /gene="Ppil1"
                     /gene_synonym="1110060O10Rik; Cypl1"
                     /inference="alignment:Splign:2.1.0"
     CDS             45..545
                     /gene="Ppil1"
                     /gene_synonym="1110060O10Rik; Cypl1"
                     /EC_number="5.2.1.8"
                     /note="PPIase; rotamase PPIL1"
                     /codon_start=1
                     /product="peptidyl-prolyl cis-trans isomerase-like 1"
                     /protein_id="NP_081121.1"
                     /db_xref="CCDS:CCDS28593.1"
                     /db_xref="GeneID:68816"
                     /db_xref="MGI:MGI:1916066"
                     /translation="MAAIPPDTWQPPNVYLETSMGVIVLELYWKHAPKTCKNFAELAR
                     RGYYNGTKFHRIIKDFMIQGGDPTGTGRGGASIYGKQFEDELHPDLKFTGAGILAMAN
                     AGPDTNGSQFFVTLAPTQWLDGKHTIFGRVCQGIGMVNRVGMVETNSQDRPVDDVKIL
                     KAYPSG"
     exon            101..255
                     /gene="Ppil1"
                     /gene_synonym="1110060O10Rik; Cypl1"
                     /inference="alignment:Splign:2.1.0"
     exon            256..324
                     /gene="Ppil1"
                     /gene_synonym="1110060O10Rik; Cypl1"
                     /inference="alignment:Splign:2.1.0"
     exon            325..1215
                     /gene="Ppil1"
                     /gene_synonym="1110060O10Rik; Cypl1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccggaagta gtgattgcta gcggggggga taccttcgct cagcatggcg gcgattcccc
       61 cagacacctg gcagccgccc aacgtctacc tggagactag catgggagtc attgtcctgg
      121 agctatactg gaagcatgcg cccaagacct gcaagaactt cgcggagctg gctcggcggg
      181 gctactacaa tggcaccaag ttccacagga tcatcaagga cttcatgatc caaggcggcg
      241 acccgacagg cacaggtcga ggtggcgcat ctatttatgg caaacagttt gaagatgagc
      301 ttcatccaga cctgaagttc actggggctg ggattctcgc catggccaac gcaggaccag
      361 acaccaatgg cagccagttc tttgtgaccc tggcccccac gcaatggctg gacggcaagc
      421 atactatttt tggccgagtg tgccagggta tagggatggt gaatcgagtg ggcatggtgg
      481 aaacaaactc ccaggaccgt cctgtggacg acgtgaagat tcttaaggcg tacccctctg
      541 gataggtggg atgctgtccc cagcactccc aggcccccgg gagctggttt ccggatgacg
      601 tagggtgctg tgtgattctg cgtcatgcat acctactccg aagcagaggg gtcgtctctg
      661 gggacgtttg tattctggcc gacagtcaca gacttgaaaa gcgggccgcg ttgatgagcg
      721 cactagctgc gcaccccctg ttcacagccc cgttcagcct ccagcgtgag ttcttccagg
      781 aatatgcaca gctcactcgc tcttccctct gagcctgagc atcaatactg ctgcttctga
      841 cactacacat cccacgcaaa gccatattga attgttgcca aatgaaaaat gcatccaaca
      901 gtcaagtgct gagaaggtgt caagtgggga tgataatgtg taatgattgg gcaatgaatc
      961 tctgagagga agcaggaagg agccttggcc atttttcccc ggggagggat gggagtctag
     1021 tgagcacaag gccgtcacag gcttcccaca ggaagtgaca tgctttaggg ctttagagaa
     1081 aataggtaag aggtttttgt gcatgatgtc cttggttttt tttttactat ttggatttca
     1141 agggagtggg gcaagaaggg tgttaatacc tatgtaatac atagaaactt acagaataaa
     1201 ccaccatggt ggttg
//
