LOCUS       NM_028677                795 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus peptidyl prolyl isomerase H (Ppih), transcript variant
            1, mRNA.
ACCESSION   NM_028677
VERSION     NM_028677.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 795)
  AUTHORS   Kuo,B.Y., Chen,Y., Bohacec,S., Johansson,O., Wasserman,W.W. and
            Simpson,E.M.
  TITLE     SAGE2Splice: unmapped SAGE tags reveal novel splice junctions
  JOURNAL   PLoS Comput Biol 2 (4), e34 (2006)
   PUBMED   16683015
REFERENCE   2  (bases 1 to 795)
  AUTHORS   Lemon,W.J., Bernert,H., Sun,H., Wang,Y. and You,M.
  TITLE     Identification of candidate lung cancer susceptibility genes in
            mouse using oligonucleotide arrays
  JOURNAL   J Med Genet 39 (9), 644-655 (2002)
   PUBMED   12205107
REFERENCE   3  (bases 1 to 795)
  AUTHORS   Ko,M.S., Threat,T.A., Wang,X., Horton,J.H., Cui,Y., Wang,X.,
            Pryor,E., Paris,J., Wells-Smith,J., Kitchen,J.R., Rowe,L.B.,
            Eppig,J., Satoh,T., Brant,L., Fujiwara,H., Yotsumoto,S. and
            Nakashima,H.
  TITLE     Genome-wide mapping of unselected transcripts from extraembryonic
            tissue of 7.5-day mouse embryos reveals enrichment in the t-complex
            and under-representation on the X chromosome
  JOURNAL   Hum Mol Genet 7 (12), 1967-1978 (1998)
   PUBMED   9811942
REFERENCE   4  (bases 1 to 795)
  AUTHORS   Zhao,Y., Greene-Till,R. and Hardies,S.C.
  TITLE     Mus spretus LINE-1s in C57BL/6J map to at least two different
            chromosomes
  JOURNAL   Mamm Genome 9 (8), 679-680 (1998)
   PUBMED   9680394
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ071503.1, AK003179.1 and BC050116.1.
            
            On Oct 24, 2007 this sequence version replaced NM_028677.3.
            
            Transcript Variant: This variant (1) represents the most
            predominant transcript. Transcript variants 1 and 2 encode the same
            isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC050116.1, DV067034.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-322               CJ071503.1         24-345
            323-776             AK003179.1         301-754
            777-795             BC050116.1         731-749
FEATURES             Location/Qualifiers
     source          1..795
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 55.34 cM"
     gene            1..795
                     /gene="Ppih"
                     /gene_synonym="1100001J08Rik; 2010111B15Rik;
                     4833408F11Rik; CYP-20; CYPH; D4Wsu43e"
                     /note="peptidyl prolyl isomerase H"
                     /db_xref="GeneID:66101"
                     /db_xref="MGI:MGI:106499"
     exon            1..115
                     /gene="Ppih"
                     /gene_synonym="1100001J08Rik; 2010111B15Rik;
                     4833408F11Rik; CYP-20; CYPH; D4Wsu43e"
                     /inference="alignment:Splign:2.1.0"
     CDS             50..583
                     /gene="Ppih"
                     /gene_synonym="1100001J08Rik; 2010111B15Rik;
                     4833408F11Rik; CYP-20; CYPH; D4Wsu43e"
                     /EC_number="5.2.1.8"
                     /note="isoform 1 is encoded by transcript variant 1;
                     rotamase H; peptidyl-prolyl cis-trans isomerase H; PPIase
                     H; cyclophilin H"
                     /codon_start=1
                     /product="peptidyl-prolyl cis-trans isomerase H isoform 1"
                     /protein_id="NP_082953.1"
                     /db_xref="CCDS:CCDS18580.1"
                     /db_xref="GeneID:66101"
                     /db_xref="MGI:MGI:106499"
                     /translation="MAVANSSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFR
                     QFCTGEFRKDGVPIGYKGSTFHRVIKDFMIQGGDFVNGDGTGVASIYRGPFADENFKL
                     RHSAPGLLSMANSGPSTNGCQFFITCSKCDWLDGKHVVFGKIIDGLLVMRKIENVPTG
                     PNNKPKLPVVISQCGEM"
     exon            116..180
                     /gene="Ppih"
                     /gene_synonym="1100001J08Rik; 2010111B15Rik;
                     4833408F11Rik; CYP-20; CYPH; D4Wsu43e"
                     /inference="alignment:Splign:2.1.0"
     exon            181..204
                     /gene="Ppih"
                     /gene_synonym="1100001J08Rik; 2010111B15Rik;
                     4833408F11Rik; CYP-20; CYPH; D4Wsu43e"
                     /inference="alignment:Splign:2.1.0"
     exon            205..249
                     /gene="Ppih"
                     /gene_synonym="1100001J08Rik; 2010111B15Rik;
                     4833408F11Rik; CYP-20; CYPH; D4Wsu43e"
                     /inference="alignment:Splign:2.1.0"
     exon            250..292
                     /gene="Ppih"
                     /gene_synonym="1100001J08Rik; 2010111B15Rik;
                     4833408F11Rik; CYP-20; CYPH; D4Wsu43e"
                     /inference="alignment:Splign:2.1.0"
     exon            293..385
                     /gene="Ppih"
                     /gene_synonym="1100001J08Rik; 2010111B15Rik;
                     4833408F11Rik; CYP-20; CYPH; D4Wsu43e"
                     /inference="alignment:Splign:2.1.0"
     exon            386..473
                     /gene="Ppih"
                     /gene_synonym="1100001J08Rik; 2010111B15Rik;
                     4833408F11Rik; CYP-20; CYPH; D4Wsu43e"
                     /inference="alignment:Splign:2.1.0"
     exon            474..514
                     /gene="Ppih"
                     /gene_synonym="1100001J08Rik; 2010111B15Rik;
                     4833408F11Rik; CYP-20; CYPH; D4Wsu43e"
                     /inference="alignment:Splign:2.1.0"
     exon            515..603
                     /gene="Ppih"
                     /gene_synonym="1100001J08Rik; 2010111B15Rik;
                     4833408F11Rik; CYP-20; CYPH; D4Wsu43e"
                     /inference="alignment:Splign:2.1.0"
     exon            604..777
                     /gene="Ppih"
                     /gene_synonym="1100001J08Rik; 2010111B15Rik;
                     4833408F11Rik; CYP-20; CYPH; D4Wsu43e"
                     /inference="alignment:Splign:2.1.0"
     regulatory      754..759
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ppih"
                     /gene_synonym="1100001J08Rik; 2010111B15Rik;
                     4833408F11Rik; CYP-20; CYPH; D4Wsu43e"
                     /note="hexamer: AATAAA"
     polyA_site      777
                     /gene="Ppih"
                     /gene_synonym="1100001J08Rik; 2010111B15Rik;
                     4833408F11Rik; CYP-20; CYPH; D4Wsu43e"
                     /note="major polyA site"
ORIGIN      
        1 tcgcgggacc tgccaccgga agccgggttt ctacttccgg gtcaaagcca tggcggtggc
       61 aaattcaagt ccagtcaatc cagtggtctt cttcgatgtc agcattggcg gccaggaagt
      121 tggtcgcatg aaaatcgagc tctttgcaga cgtggtgcct aagacggcag agaactttag
      181 gcaattctgc accggagagt tcagaaaaga tggcgttccg ataggataca aaggaagcac
      241 cttccacagg gtcataaagg atttcatgat tcagggtgga gattttgtta atggcgatgg
      301 cactggagtc gccagtattt accggggtcc atttgcggat gaaaatttta aacttagaca
      361 ctctgctcca ggcctgcttt ccatggcaaa cagtggtccc agtacaaatg gctgccagtt
      421 ctttatcacg tgttctaagt gtgattggct ggatggaaag catgtagtgt ttggaaaaat
      481 cattgacgga cttctagtga tgaggaagat cgagaatgtt cccacaggcc ccaacaataa
      541 gcccaaactg ccagtggtga tctcacagtg tggggaaatg taatctagac aagacggaac
      601 caggtcctct gctgttttgg tgtgacattc tctctcgagt ctgacaagct ggactggcct
      661 ctgtgtttgc ttccctgtct ccacagtatg cgatccagga cctggaagta tcacaaacga
      721 gaaccaatca tcctgtttac attttggact gtaaataaag gaattttttt taatgcaaaa
      781 aaaaaaaaaa aaaaa
//
