LOCUS       NM_001407484            6271 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus peptidyl-prolyl isomerase G (cyclophilin G) (Ppig),
            transcript variant 20, mRNA.
ACCESSION   NM_001407484
VERSION     NM_001407484.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6271)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL845261.17.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5286963.40783.1,
                                           SRR14777534.851328.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN00849375,
                                           SAMN00849380 [ECO:0000350]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-285               AL845261.17        39941-40225
            286-353             AL845261.17        48608-48675
            354-431             AL845261.17        49059-49136
            432-506             AL845261.17        49242-49316
            507-614             AL845261.17        49680-49787
            615-659             AL845261.17        50051-50095
            660-747             AL845261.17        51153-51240
            748-929             AL845261.17        52809-52990
            930-1137            AL845261.17        58348-58555
            1138-1305           AL845261.17        60475-60642
            1306-1393           AL845261.17        62890-62977
            1394-1530           AL845261.17        65823-65959
            1531-6271           AL845261.17        66134-70874
FEATURES             Location/Qualifiers
     source          1..6271
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 40.95 cM"
     gene            1..6271
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /note="peptidyl-prolyl isomerase G (cyclophilin G)"
                     /db_xref="GeneID:228005"
                     /db_xref="MGI:MGI:2445173"
     exon            1..285
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            286..353
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            354..431
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            432..506
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            507..614
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            615..659
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            660..747
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            748..929
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            930..1137
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            1138..1305
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     CDS             1235..2641
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /EC_number="5.2.1.8"
                     /note="isoform 8 is encoded by transcript variant 20;
                     peptidylprolyl isomerase G; peptidyl-prolyl cis-trans
                     isomerase G; PPIase G; rotamase G; cyclophilin G"
                     /codon_start=1
                     /product="peptidyl-prolyl cis-trans isomerase G isoform 8"
                     /protein_id="NP_001394413.1"
                     /db_xref="GeneID:228005"
                     /db_xref="MGI:MGI:2445173"
                     /translation="MRKSPPKADDKERKNRERERERECNPPNSQPASYQRRFLVTRSG
                     RKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSEL
                     NEIKENQRSPVRVKEKKITDHRHMSESPNRKVEKEKKAKDHKSESKERDIRRNSEKDD
                     KYNKNKVKKRGKSKSRSKSKERSKSKERDSKHSRHEDKRVRSRSKERDHETTKEKEKP
                     LDPKGKDQERSRSKENSKQVESKSNEHDHSKSKEKDRRAQSRSRERDLTKSKHSYNSR
                     TRERSRSRDRSRRVRSRSHDRDRSRSKEYHRYREQEYRRRGRSRSRDRRTPGRSRSKD
                     RRRRRRDSRSSEREESQSRNKDKYRSQESKSSHRKENSEGEKRTYSKSRDHNSSSNNR
                     EKKADREQSPVSKTKQSSQDNEVKSSTLKNQEDEKTRSPVEKENQKSKGQENDHVHDK
                     NKKCDHESSPGTDEDKSG"
     exon            1306..1393
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            1394..1530
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            1531..6271
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2858..2863
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /note="hexamer: AATGAA"
     polyA_site      2876
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /note="major polyA site"
     regulatory      3964..3969
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /note="hexamer: AATAAA"
     polyA_site      3995
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
     regulatory      6248..6253
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /note="hexamer: AATAAA"
     polyA_site      6271
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /note="major polyA site"
ORIGIN      
        1 ctttccgtcg aggtctctgg gctgctcggg ctcggagggg tggccccggg gaccgcggcg
       61 cggcctgggg ccccgtggtg gcccggcggc ttgcagccga gccccggggc gaaggaagcg
      121 gctcttcctc tccagccccc gccctcccgg ctcgggcgca cacctcctcc ctgacgcatt
      181 ttgccgcaca agctgtaata tggcggcagc gacggcagcc tcggctcccg ggagctaggt
      241 tcgttttgga ggcttcagaa ccgggagacg gagcgctgcg gcgtggagca aaacaattgg
      301 ctcagtcatt cttggtggat ttttgttttt ttattgtttc ccccaactta aagactgaag
      361 tgttggaacc atggggataa aggtccagcg tcctcggtgt ttttttgaca ttgccattaa
      421 taatcaacct gctggaagag ttgtctttga attattttcc gatgtatgtc ccaaaacgtg
      481 tgagaacttt cgctgccttt gcacaggtga aaaagggaca gggaaatcaa ctcagaagcc
      541 attacattat aagagctgtc tctttcatag agttgtcaag gatttcatgg ttcagggtgg
      601 tgacttcagt gaagggaatg gaagaggagg agaatctatt tatggaggat tctttgaaga
      661 tgagagtttt gctgttaaac acaacaaaga gtttctctta tcaatggcca acagagggaa
      721 ggatacaaat ggctctcagt tctttatagt aagaagcttt tatttaataa tttttacatg
      781 acattttagg catcatgttg tttttgggca agtgatctct ggtcaggaag ttgtgagaga
      841 gattgaaaac cagaaaacag atgccgctag caaaccattt gctgaagttc ggatactcag
      901 ttgcggagag ctgattccaa agtctaaggt taagaaagaa gaaaagaaaa ggcataagtc
      961 ctcgtcctcc tcctcctcca gtgactcaga cagctcaagc gattctcagt cctcctctga
     1021 gtcttctgat tctgaaagcg cttccgaaga aaaatccaga aaaaggaaaa agaaacatag
     1081 gaaaaattcc cgaaagcata agaaggagaa gaagaagcga aagaaaagca agaaaagccc
     1141 atctagtgaa agtgaagcag aaaatgttga tgcacagccc cagtctactg tccgtccaga
     1201 agagatccct cctataccag aaaatagatt tctaatgaga aaaagtcctc ctaaagccga
     1261 tgacaaggag aggaaaaaca gagagagaga aagagaaaga gagtgtaatc cacctaactc
     1321 ccagcctgct tcataccagc gacgattctt agttactagg tctggcagga aaattaaagg
     1381 aagaggaccg aggcgttatc gaactccttc cagatccaga tcgagggatc gattcagacg
     1441 aagtgagact cctccacatt ggagacaaga gatgcagaga gctcagagaa tgagggtgtc
     1501 aagtggtgaa agatggatca aaggggataa gagtgagtta aatgaaataa aagaaaatca
     1561 aaggagccca gttagagtaa aagagaaaaa aataacagat cacagacaca tgtctgagag
     1621 tccaaacaga aaagtagaaa aggaaaagaa agctaaagac cataaatctg aaagcaaaga
     1681 gagagacatc agaagaaatt cagaaaaaga tgataaatat aacaaaaaca aagtgaagaa
     1741 aaggggcaaa tccaagagta ggagcaagag caaggagaga tccaagagta aggagcgaga
     1801 ctcgaagcac agcagacacg aagacaagag ggtgaggtca agaagtaaag aaagggatca
     1861 tgagactact aaagaaaaag aaaaaccact ggatcctaaa gggaaagatc aggaaaggag
     1921 tagaagcaaa gagaactcca aacaggtaga atcaaaaagt aatgaacatg atcatagcaa
     1981 aagtaaagaa aaggatagac gtgcacagtc caggagtaga gaacgggatc tgactaaaag
     2041 taaacacagt tacaacagta gaacaaggga gcggagcaga agtagggaca ggagcagaag
     2101 agtgcggtcc agaagccacg acagagatcg cagcagaagc aaggagtacc atagatacag
     2161 agaacaggag tataggagaa gaggaaggtc acgaagccgg gatcgaagaa cgccaggacg
     2221 atcgagaagt aaagatagga ggagaagaag gagggattcc cggagctcag agagagaaga
     2281 aagtcaaagt agaaacaaag ataaatatag aagccaagaa agtaagagtt cacacagaaa
     2341 agaaaattct gagggtgaga aaagaacgta ctctaaaagt cgtgatcata atagctcaag
     2401 taataacagg gaaaaaaagg ctgatagaga gcaaagtcca gtgtcaaaaa caaagcaaag
     2461 cagtcaggac aatgaagtga agtcctccac attaaaaaat caagaggacg aaaagaccag
     2521 atccccggtg gaaaaagaaa accaaaaatc aaagggtcaa gaaaatgacc atgtacatga
     2581 caaaaataaa aaatgtgatc atgaatcaag ccctggaaca gatgaagaca aaagtggatg
     2641 agtgagttgt gtactcttaa ttccttcctg tctcaaattt tcagttttta agacttactg
     2701 ttgaacctcc cttttttatt gttttcattg ttttggagtt gtttatgttt gtctcccccc
     2761 accccctttt tttttttaaa tgtggacttc attgagttga tcttttgata atctgctacc
     2821 tggataattt gtactgctaa agttttaata aacttgaaat gaaaagaaaa acaacacttt
     2881 ggtgtaatac tgtgtgctat gttaaattct tatgtattca tttttgtgtt gcaaccgtca
     2941 atagcagcct actttgctta atcagccatt tggaaacaag cttaactgtt ggttgcagta
     3001 cattgttgta taggcttgtg tttcttttga tacaaatccc tttagaaacc acttgaagtt
     3061 ttgtatagct ttttgggctt tgatttttca tttataattc atgggcttag agcagtttcc
     3121 ttaactaaca gaagcaggat ccttatgtga tcttaaacct tcatttgatt ttacagttat
     3181 ttgtacttta gttacttttt ttgtgcttta taccttatac tttacaattc cagctgtagc
     3241 ttgtttctta atattgtcca cgttgctctg cgagctataa aaatgaggtg agtgctgttt
     3301 tcagttcatg tgctgattga gcttgagttg ctgttataca gcatttgaca gaaattagac
     3361 cttggaagac cagactgtaa ttttcaattc tttgttgctt ttggtgtgaa gagctgaaat
     3421 tgttgctttt taagaacatg ttattacctt tttctacaat ttaaaaaatg catttctcat
     3481 taaaacatac tacttgtgta gatccttctt aagctagaca gattctaaaa agcgttagta
     3541 ttggaaataa gatttcccta ttttggctat tagcctatat cacattgagt ggtaattctg
     3601 catgatttgg gtttgttttt tgtttttttt tttttaaact tggactaact tctctgattc
     3661 tcatagctgt gaatatgaaa tgtcaagaag atgcatcttt ctatatatgt accatgatag
     3721 gctgtgtagc atgtttgtga ctctggtttc tttctattca gatggcttta gaccagttta
     3781 ctgttaacat tattttaact tggcatgtat aacattgcca tataaagtag aatagaaagt
     3841 tgcaaaatat gataccgtgc agagttaaac actaaacata tccaaagtcc attcagaatt
     3901 ttgtgtgttg tattttgcta tttttttgtg atgtgtggcc ttttattctg taatatcctt
     3961 ctaaataaaa cattgaacat ccagcaaaca caaaacctgc ctcatttgag aaatatttca
     4021 aaaatccaat taatagtagc ctttaggacg tttttgtact ctaatatttg tcagtatagt
     4081 gtcagctctt accaaggtag cttcttggta aacccactag cttttcaatg atatttgtac
     4141 tgaataaagt gatgcttaat atacttccca ttattgatta ctatggtaag atatatttgg
     4201 cattgtagct ggtacagaat gaagagtgca gtgattataa agctatttgg aacatcctaa
     4261 agcaaatacc cacaatggat tctttacaaa tagtttttct tgatgggaat agttaatata
     4321 tacgtgatct gttacatgtc ttaaaaagtt gattatgtct taaattcagt tgtgttttaa
     4381 aatatatccc aaactacctg atctttaaga aaggaatttc aacaaacatt ttaaaatcca
     4441 tacttttttt aagtaaaatt actttttttt tcttatctag agcttttact tgttagcata
     4501 tacattataa acaagaactt tccagttctt taggaaagta aacatgggag aaaattggta
     4561 atgtctgtaa tatcctccaa gagagcagct cagagctgag catttacggg ctcccccaac
     4621 tcctgctttg ttagtttgtt atttttttca atatgacaga taatggggta aatagttgag
     4681 aaaagacaat ctagattttt ttttcagaat aaataattaa cagcattaat tgtaccccaa
     4741 gattcacagt tatcaattgc acaaagccca aattcttgtt ctagtagatt tttagttatt
     4801 tgtacatcat attcccaaaa ctatttccca tttcaatttt cccatcacat tggctttcta
     4861 agaatatcta aatttacagc taatgaatag tttttaatac cccttgaaag tactttcact
     4921 tgtttttatt gcttgactcc aaagctgagg aaattatttc agtatgtaag actttgatga
     4981 ttattgtatg aattattgtt ctggataagt tgtttaccac agaaattgac actacaaaga
     5041 gatcgttaga gaaagtaaag ctactgtatt gtactgcatt gtagctgata cagaatggtt
     5101 acttgctgta aagacaagac tgtctgggaa cagctatcca acgtttaaag tgctctttca
     5161 cttaaaagtt atgctaatct gctagctttc tttgccccag tgtgatccag ctgctcactg
     5221 gctttgcttg catccagtgg taggtgtcaa accaagaacc tttatgttct ggataggcac
     5281 atgctggggt tctggtattt tgggtaatag tattaactac tgctcctact ttattttcta
     5341 gtgactactt agagcagtta gtataattga tcctttgttc catgtgttaa tagctttcat
     5401 catggaacct tttacagcaa atttctgtaa atttcccaga aaggacttag acttaactga
     5461 ttggtataaa aaactaaatg agcatttttc attcttttgt ttctatttac tgtaattatt
     5521 ccctgtaggg tttatgcatt tacagttgac aaactctctg tgtagtttga gaaactttaa
     5581 ttgtaagaat atatttttaa actaattgtt tttaaaaata aagtatccca aggaaactga
     5641 gtgttgattg ccattactgc ctgcagtggg cttctcaatg tcttgaaggg attcacctgc
     5701 tgtgtgacaa ataaacaaca aatcacattc atttaaaaaa aaaaaaaagg ccgcacaggc
     5761 caaagaggaa gaagtgttaa ggttttactc atttgctctc cctgactcac ccctagtact
     5821 ggaggatgga agggcattca ttggtttgta tttctgtctg gttttggttt tcttttatag
     5881 acaattccat gttactaaaa gcacattctc tgtatttctg ccccaccctc tttgtgtgtt
     5941 tatagtattt ttgaaagatt gacacataaa ttgggtattt ctatggaatc ttgaggtgtg
     6001 gctgctctct gtggaagggg aaagcataat taggttaatg cacttctttt cctagctcca
     6061 cagtcactgt gatgtatatt tttttaatgg aatttagaaa acttgttttc tcaattgtaa
     6121 aattagttta aagatgctgc ttctcttatc attagtctag taaatgttga actgttttct
     6181 gcagatggca ttttacaaaa tttaaacttc aaaactgtat taacttttat agttaaacat
     6241 tgtattaaat aaagtatact acaataaaca a
//
