LOCUS       NM_001407478            6263 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus peptidyl-prolyl isomerase G (cyclophilin G) (Ppig),
            transcript variant 14, mRNA.
ACCESSION   NM_001407478
VERSION     NM_001407478.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6263)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL845261.17.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13422600.1742985.1,
                                           ERR3363658.5789184.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN00849375,
                                           SAMN00849380 [ECO:0000350]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-285               AL845261.17        39941-40225
            286-353             AL845261.17        48608-48675
            354-431             AL845261.17        49059-49136
            432-506             AL845261.17        49242-49316
            507-614             AL845261.17        49680-49787
            615-659             AL845261.17        50051-50095
            660-751             AL845261.17        51153-51244
            752-781             AL845261.17        52730-52759
            782-921             AL845261.17        52851-52990
            922-1129            AL845261.17        58348-58555
            1130-1297           AL845261.17        60475-60642
            1298-1385           AL845261.17        62890-62977
            1386-1522           AL845261.17        65823-65959
            1523-6263           AL845261.17        66134-70874
FEATURES             Location/Qualifiers
     source          1..6263
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 40.95 cM"
     gene            1..6263
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /note="peptidyl-prolyl isomerase G (cyclophilin G)"
                     /db_xref="GeneID:228005"
                     /db_xref="MGI:MGI:2445173"
     exon            1..285
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            286..353
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            354..431
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            432..506
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     CDS             462..2633
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /EC_number="5.2.1.8"
                     /note="isoform 9 is encoded by transcript variant 14;
                     peptidylprolyl isomerase G; peptidyl-prolyl cis-trans
                     isomerase G; PPIase G; rotamase G; cyclophilin G"
                     /codon_start=1
                     /product="peptidyl-prolyl cis-trans isomerase G isoform 9"
                     /protein_id="NP_001394407.1"
                     /db_xref="GeneID:228005"
                     /db_xref="MGI:MGI:2445173"
                     /translation="MYVPKRVRTFAAFAQVKKGQGNQLRSHYIIRAVSFIELSRISWF
                     RVVTSVKGMEEEENLFMEDSLKMRVLLLNTTKSFSYQWPTEGRIQMALSSLCITTKPT
                     PHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKK
                     RHKSSSSSSSSDSDSSSDSQSSSESSDSESASEEKSRKRKKKHRKNSRKHKKEKKKRK
                     KSKKSPSSESEAENVDAQPQSTVRPEEIPPIPENRFLMRKSPPKADDKERKNRERERE
                     RECNPPNSQPASYQRRFLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQE
                     MQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKEKKITDHRHMSESPNRKVEKE
                     KKAKDHKSESKERDIRRNSEKDDKYNKNKVKKRGKSKSRSKSKERSKSKERDSKHSRH
                     EDKRVRSRSKERDHETTKEKEKPLDPKGKDQERSRSKENSKQVESKSNEHDHSKSKEK
                     DRRAQSRSRERDLTKSKHSYNSRTRERSRSRDRSRRVRSRSHDRDRSRSKEYHRYREQ
                     EYRRRGRSRSRDRRTPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRSQESKSSHRK
                     ENSEGEKRTYSKSRDHNSSSNNREKKADREQSPVSKTKQSSQDNEVKSSTLKNQEDEK
                     TRSPVEKENQKSKGQENDHVHDKNKKCDHESSPGTDEDKSG"
     exon            507..614
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            615..659
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            660..751
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            752..781
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            782..921
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            922..1129
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            1130..1297
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            1298..1385
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            1386..1522
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            1523..6263
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2850..2855
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /note="hexamer: AATGAA"
     polyA_site      2868
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /note="major polyA site"
     regulatory      3956..3961
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /note="hexamer: AATAAA"
     polyA_site      3987
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
     regulatory      6240..6245
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /note="hexamer: AATAAA"
     polyA_site      6263
                     /gene="Ppig"
                     /gene_synonym="B230312B02Rik; CYP; SRCyp"
                     /note="major polyA site"
ORIGIN      
        1 ctttccgtcg aggtctctgg gctgctcggg ctcggagggg tggccccggg gaccgcggcg
       61 cggcctgggg ccccgtggtg gcccggcggc ttgcagccga gccccggggc gaaggaagcg
      121 gctcttcctc tccagccccc gccctcccgg ctcgggcgca cacctcctcc ctgacgcatt
      181 ttgccgcaca agctgtaata tggcggcagc gacggcagcc tcggctcccg ggagctaggt
      241 tcgttttgga ggcttcagaa ccgggagacg gagcgctgcg gcgtggagca aaacaattgg
      301 ctcagtcatt cttggtggat ttttgttttt ttattgtttc ccccaactta aagactgaag
      361 tgttggaacc atggggataa aggtccagcg tcctcggtgt ttttttgaca ttgccattaa
      421 taatcaacct gctggaagag ttgtctttga attattttcc gatgtatgtc ccaaaacgtg
      481 tgagaacttt cgctgccttt gcacaggtga aaaagggaca gggaaatcaa ctcagaagcc
      541 attacattat aagagctgtc tctttcatag agttgtcaag gatttcatgg ttcagggtgg
      601 tgacttcagt gaagggaatg gaagaggagg agaatctatt tatggaggat tctttgaaga
      661 tgagagtttt gctgttaaac acaacaaaga gtttctctta tcaatggcca acagagggaa
      721 ggatacaaat ggctctcagt tctttatgta taacaacaaa accaactcct catttagatg
      781 ggcatcatgt tgtttttggg caagtgatct ctggtcagga agttgtgaga gagattgaaa
      841 accagaaaac agatgccgct agcaaaccat ttgctgaagt tcggatactc agttgcggag
      901 agctgattcc aaagtctaag gttaagaaag aagaaaagaa aaggcataag tcctcgtcct
      961 cctcctcctc cagtgactca gacagctcaa gcgattctca gtcctcctct gagtcttctg
     1021 attctgaaag cgcttccgaa gaaaaatcca gaaaaaggaa aaagaaacat aggaaaaatt
     1081 cccgaaagca taagaaggag aagaagaagc gaaagaaaag caagaaaagc ccatctagtg
     1141 aaagtgaagc agaaaatgtt gatgcacagc cccagtctac tgtccgtcca gaagagatcc
     1201 ctcctatacc agaaaataga tttctaatga gaaaaagtcc tcctaaagcc gatgacaagg
     1261 agaggaaaaa cagagagaga gaaagagaaa gagagtgtaa tccacctaac tcccagcctg
     1321 cttcatacca gcgacgattc ttagttacta ggtctggcag gaaaattaaa ggaagaggac
     1381 cgaggcgtta tcgaactcct tccagatcca gatcgaggga tcgattcaga cgaagtgaga
     1441 ctcctccaca ttggagacaa gagatgcaga gagctcagag aatgagggtg tcaagtggtg
     1501 aaagatggat caaaggggat aagagtgagt taaatgaaat aaaagaaaat caaaggagcc
     1561 cagttagagt aaaagagaaa aaaataacag atcacagaca catgtctgag agtccaaaca
     1621 gaaaagtaga aaaggaaaag aaagctaaag accataaatc tgaaagcaaa gagagagaca
     1681 tcagaagaaa ttcagaaaaa gatgataaat ataacaaaaa caaagtgaag aaaaggggca
     1741 aatccaagag taggagcaag agcaaggaga gatccaagag taaggagcga gactcgaagc
     1801 acagcagaca cgaagacaag agggtgaggt caagaagtaa agaaagggat catgagacta
     1861 ctaaagaaaa agaaaaacca ctggatccta aagggaaaga tcaggaaagg agtagaagca
     1921 aagagaactc caaacaggta gaatcaaaaa gtaatgaaca tgatcatagc aaaagtaaag
     1981 aaaaggatag acgtgcacag tccaggagta gagaacggga tctgactaaa agtaaacaca
     2041 gttacaacag tagaacaagg gagcggagca gaagtaggga caggagcaga agagtgcggt
     2101 ccagaagcca cgacagagat cgcagcagaa gcaaggagta ccatagatac agagaacagg
     2161 agtataggag aagaggaagg tcacgaagcc gggatcgaag aacgccagga cgatcgagaa
     2221 gtaaagatag gaggagaaga aggagggatt cccggagctc agagagagaa gaaagtcaaa
     2281 gtagaaacaa agataaatat agaagccaag aaagtaagag ttcacacaga aaagaaaatt
     2341 ctgagggtga gaaaagaacg tactctaaaa gtcgtgatca taatagctca agtaataaca
     2401 gggaaaaaaa ggctgataga gagcaaagtc cagtgtcaaa aacaaagcaa agcagtcagg
     2461 acaatgaagt gaagtcctcc acattaaaaa atcaagagga cgaaaagacc agatccccgg
     2521 tggaaaaaga aaaccaaaaa tcaaagggtc aagaaaatga ccatgtacat gacaaaaata
     2581 aaaaatgtga tcatgaatca agccctggaa cagatgaaga caaaagtgga tgagtgagtt
     2641 gtgtactctt aattccttcc tgtctcaaat tttcagtttt taagacttac tgttgaacct
     2701 ccctttttta ttgttttcat tgttttggag ttgtttatgt ttgtctcccc ccaccccctt
     2761 ttttttttta aatgtggact tcattgagtt gatcttttga taatctgcta cctggataat
     2821 ttgtactgct aaagttttaa taaacttgaa atgaaaagaa aaacaacact ttggtgtaat
     2881 actgtgtgct atgttaaatt cttatgtatt catttttgtg ttgcaaccgt caatagcagc
     2941 ctactttgct taatcagcca tttggaaaca agcttaactg ttggttgcag tacattgttg
     3001 tataggcttg tgtttctttt gatacaaatc cctttagaaa ccacttgaag ttttgtatag
     3061 ctttttgggc tttgattttt catttataat tcatgggctt agagcagttt ccttaactaa
     3121 cagaagcagg atccttatgt gatcttaaac cttcatttga ttttacagtt atttgtactt
     3181 tagttacttt ttttgtgctt tataccttat actttacaat tccagctgta gcttgtttct
     3241 taatattgtc cacgttgctc tgcgagctat aaaaatgagg tgagtgctgt tttcagttca
     3301 tgtgctgatt gagcttgagt tgctgttata cagcatttga cagaaattag accttggaag
     3361 accagactgt aattttcaat tctttgttgc ttttggtgtg aagagctgaa attgttgctt
     3421 tttaagaaca tgttattacc tttttctaca atttaaaaaa tgcatttctc attaaaacat
     3481 actacttgtg tagatccttc ttaagctaga cagattctaa aaagcgttag tattggaaat
     3541 aagatttccc tattttggct attagcctat atcacattga gtggtaattc tgcatgattt
     3601 gggtttgttt tttgtttttt tttttttaaa cttggactaa cttctctgat tctcatagct
     3661 gtgaatatga aatgtcaaga agatgcatct ttctatatat gtaccatgat aggctgtgta
     3721 gcatgtttgt gactctggtt tctttctatt cagatggctt tagaccagtt tactgttaac
     3781 attattttaa cttggcatgt ataacattgc catataaagt agaatagaaa gttgcaaaat
     3841 atgataccgt gcagagttaa acactaaaca tatccaaagt ccattcagaa ttttgtgtgt
     3901 tgtattttgc tatttttttg tgatgtgtgg ccttttattc tgtaatatcc ttctaaataa
     3961 aacattgaac atccagcaaa cacaaaacct gcctcatttg agaaatattt caaaaatcca
     4021 attaatagta gcctttagga cgtttttgta ctctaatatt tgtcagtata gtgtcagctc
     4081 ttaccaaggt agcttcttgg taaacccact agcttttcaa tgatatttgt actgaataaa
     4141 gtgatgctta atatacttcc cattattgat tactatggta agatatattt ggcattgtag
     4201 ctggtacaga atgaagagtg cagtgattat aaagctattt ggaacatcct aaagcaaata
     4261 cccacaatgg attctttaca aatagttttt cttgatggga atagttaata tatacgtgat
     4321 ctgttacatg tcttaaaaag ttgattatgt cttaaattca gttgtgtttt aaaatatatc
     4381 ccaaactacc tgatctttaa gaaaggaatt tcaacaaaca ttttaaaatc catacttttt
     4441 ttaagtaaaa ttactttttt tttcttatct agagctttta cttgttagca tatacattat
     4501 aaacaagaac tttccagttc tttaggaaag taaacatggg agaaaattgg taatgtctgt
     4561 aatatcctcc aagagagcag ctcagagctg agcatttacg ggctccccca actcctgctt
     4621 tgttagtttg ttattttttt caatatgaca gataatgggg taaatagttg agaaaagaca
     4681 atctagattt ttttttcaga ataaataatt aacagcatta attgtacccc aagattcaca
     4741 gttatcaatt gcacaaagcc caaattcttg ttctagtaga tttttagtta tttgtacatc
     4801 atattcccaa aactatttcc catttcaatt ttcccatcac attggctttc taagaatatc
     4861 taaatttaca gctaatgaat agtttttaat accccttgaa agtactttca cttgttttta
     4921 ttgcttgact ccaaagctga ggaaattatt tcagtatgta agactttgat gattattgta
     4981 tgaattattg ttctggataa gttgtttacc acagaaattg acactacaaa gagatcgtta
     5041 gagaaagtaa agctactgta ttgtactgca ttgtagctga tacagaatgg ttacttgctg
     5101 taaagacaag actgtctggg aacagctatc caacgtttaa agtgctcttt cacttaaaag
     5161 ttatgctaat ctgctagctt tctttgcccc agtgtgatcc agctgctcac tggctttgct
     5221 tgcatccagt ggtaggtgtc aaaccaagaa cctttatgtt ctggataggc acatgctggg
     5281 gttctggtat tttgggtaat agtattaact actgctccta ctttattttc tagtgactac
     5341 ttagagcagt tagtataatt gatcctttgt tccatgtgtt aatagctttc atcatggaac
     5401 cttttacagc aaatttctgt aaatttccca gaaaggactt agacttaact gattggtata
     5461 aaaaactaaa tgagcatttt tcattctttt gtttctattt actgtaatta ttccctgtag
     5521 ggtttatgca tttacagttg acaaactctc tgtgtagttt gagaaacttt aattgtaaga
     5581 atatattttt aaactaattg tttttaaaaa taaagtatcc caaggaaact gagtgttgat
     5641 tgccattact gcctgcagtg ggcttctcaa tgtcttgaag ggattcacct gctgtgtgac
     5701 aaataaacaa caaatcacat tcatttaaaa aaaaaaaaaa ggccgcacag gccaaagagg
     5761 aagaagtgtt aaggttttac tcatttgctc tccctgactc acccctagta ctggaggatg
     5821 gaagggcatt cattggtttg tatttctgtc tggttttggt tttcttttat agacaattcc
     5881 atgttactaa aagcacattc tctgtatttc tgccccaccc tctttgtgtg tttatagtat
     5941 ttttgaaaga ttgacacata aattgggtat ttctatggaa tcttgaggtg tggctgctct
     6001 ctgtggaagg ggaaagcata attaggttaa tgcacttctt ttcctagctc cacagtcact
     6061 gtgatgtata tttttttaat ggaatttaga aaacttgttt tctcaattgt aaaattagtt
     6121 taaagatgct gcttctctta tcattagtct agtaaatgtt gaactgtttt ctgcagatgg
     6181 cattttacaa aatttaaact tcaaaactgt attaactttt atagttaaac attgtattaa
     6241 ataaagtata ctacaataaa caa
//
