LOCUS       NM_008908               1286 bp    mRNA    linear   ROD 06-APR-2024
DEFINITION  Mus musculus peptidylprolyl isomerase C (Ppic), mRNA.
ACCESSION   NM_008908
VERSION     NM_008908.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1286)
  AUTHORS   Paiva,R.S., Ramos,C.V., Azenha,S.R., Alves,C., Basto,A.P., Graca,L.
            and Martins,V.C.
  TITLE     Peptidylprolyl isomerase C (Ppic) regulates invariant Natural
            Killer T cell (iNKT) differentiation in mice
  JOURNAL   Eur J Immunol 51 (8), 1968-1979 (2021)
   PUBMED   33864384
  REMARK    GeneRIF: Peptidylprolyl isomerase C (Ppic) regulates invariant
            Natural Killer T cell (iNKT) differentiation in mice.
REFERENCE   2  (bases 1 to 1286)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1286)
  AUTHORS   Chan,W.Y., Wu,S.M., Ruszczyk,L., Law,E., Lee,T.L., Baxendale,V.,
            Lap-Yin Pang,A. and Rennert,O.M.
  TITLE     The complexity of antisense transcription revealed by the study of
            developing male germ cells
  JOURNAL   Genomics 87 (6), 681-692 (2006)
   PUBMED   16458478
REFERENCE   4  (bases 1 to 1286)
  AUTHORS   Lepourcelet,M., Tou,L., Cai,L., Sawada,J., Lazar,A.J.,
            Glickman,J.N., Williamson,J.A., Everett,A.D., Redston,M., Fox,E.A.,
            Nakatani,Y. and Shivdasani,R.A.
  TITLE     Insights into developmental mechanisms and cancers in the mammalian
            intestine derived from serial analysis of gene expression and study
            of the hepatoma-derived growth factor (HDGF)
  JOURNAL   Development 132 (2), 415-427 (2005)
   PUBMED   15604097
REFERENCE   5  (bases 1 to 1286)
  AUTHORS   Innis,J.W., Mortlock,D., Chen,Z., Ludwig,M., Williams,M.E.,
            Williams,T.M., Doyle,C.D., Shao,Z., Glynn,M., Mikulic,D.,
            Lehmann,K., Mundlos,S. and Utsch,B.
  TITLE     Polyalanine expansion in HOXA13: three new affected families and
            the molecular consequences in a mouse model
  JOURNAL   Hum Mol Genet 13 (22), 2841-2851 (2004)
   PUBMED   15385446
REFERENCE   6  (bases 1 to 1286)
  AUTHORS   Friedman,J., Weissman,I., Friedman,J. and Alpert,S.
  TITLE     An analysis of the expression of cyclophilin C reveals tissue
            restriction and an intriguing pattern in the mouse kidney
  JOURNAL   Am J Pathol 144 (6), 1247-1256 (1994)
   PUBMED   8203464
REFERENCE   7  (bases 1 to 1286)
  AUTHORS   Ke,H., Zhao,Y., Luo,F., Weissman,I. and Friedman,J.
  TITLE     Crystal structure of murine cyclophilin C complexed with
            immunosuppressive drug cyclosporin A
  JOURNAL   Proc Natl Acad Sci U S A 90 (24), 11850-11854 (1993)
   PUBMED   8265636
REFERENCE   8  (bases 1 to 1286)
  AUTHORS   Friedman,J., Trahey,M. and Weissman,I.
  TITLE     Cloning and characterization of cyclophilin C-associated protein: a
            candidate natural cellular ligand for cyclophilin C
  JOURNAL   Proc Natl Acad Sci U S A 90 (14), 6815-6819 (1993)
   PUBMED   8341703
REFERENCE   9  (bases 1 to 1286)
  AUTHORS   Walsh,C.T., Zydowsky,L.D. and McKeon,F.D.
  TITLE     Cyclosporin A, the cyclophilin class of peptidylprolyl isomerases,
            and blockade of T cell signal transduction
  JOURNAL   J Biol Chem 267 (19), 13115-13118 (1992)
   PUBMED   1618811
  REMARK    Review article
REFERENCE   10 (bases 1 to 1286)
  AUTHORS   Friedman,J. and Weissman,I.
  TITLE     Two cytoplasmic candidates for immunophilin action are revealed by
            affinity for a new cyclophilin: one in the presence and one in the
            absence of CsA
  JOURNAL   Cell 66 (4), 799-806 (1991)
   PUBMED   1652374
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC109291.12.
            
            On Oct 19, 2007 this sequence version replaced NM_008908.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK168911.1, AK131931.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-168               AC109291.12        166590-166757       c
            169-282             AC109291.12        160256-160369       c
            283-376             AC109291.12        159737-159830       c
            377-561             AC109291.12        157875-158059       c
            562-1286            AC109291.12        155091-155815       c
FEATURES             Location/Qualifiers
     source          1..1286
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 29.03 cM"
     gene            1..1286
                     /gene="Ppic"
                     /gene_synonym="CyP-20c"
                     /note="peptidylprolyl isomerase C"
                     /db_xref="GeneID:19038"
                     /db_xref="MGI:MGI:97751"
     exon            1..168
                     /gene="Ppic"
                     /gene_synonym="CyP-20c"
                     /inference="alignment:Splign:2.1.0"
     exon            169..282
                     /gene="Ppic"
                     /gene_synonym="CyP-20c"
                     /inference="alignment:Splign:2.1.0"
     exon            283..376
                     /gene="Ppic"
                     /gene_synonym="CyP-20c"
                     /inference="alignment:Splign:2.1.0"
     exon            377..561
                     /gene="Ppic"
                     /gene_synonym="CyP-20c"
                     /inference="alignment:Splign:2.1.0"
     exon            562..1286
                     /gene="Ppic"
                     /gene_synonym="CyP-20c"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccggagccta aggttgcgcc cgtgccatcg ttgccacttc caccgcgcac catgagcccg
       61 ggtccccgtc tgctgctgcc cgcggtgctc tgcctggggc ttggagccct ggtgtcttct
      121 tcggggtcct caggcgtccg aaaacgaggt ccctcggtga cggacaaggt cttctttgat
      181 gtgaggatcg gagacaaaga tgtgggtaga attgtgattg gcctctttgg aaacgttgta
      241 cccaagacgg tggaaaactt cgtggctctg gcaacaggag agaaaggcta cgggtacaag
      301 ggcagcatct tccaccgtgt catcaaggac ttcatgattc aaggagggga cttcacagct
      361 agagatggca ctggagggat gagcatctat ggtgagacat ttccggatga gaacttcaaa
      421 ctgaagcact atggcattgg ctgggtcagc atggccaatg ctggaccaga caccaacgga
      481 tcccagttct tcatcacctt gaccaagccc acctggttgg atggcaaaca cgttgtattt
      541 ggaaaagtcc tagatgggat gactgtggta cattccattg aacttcaagc aacagatggc
      601 catgaccgcc cactcaccga ctgcaccatc gtcaacagtg gcaagataga tgtgaaaaca
      661 ccctttgtgg ttgaggtccc tgattggtga cagaaatggc ggaagacagg aaacacactg
      721 gctggcccat gtgcacatct gtgatccacc agcagtcttt tagttactta aaagttgtag
      781 ttaaaaaaat ttctcattta attttccagt ctcgattgca ataacaaaat caaccacaca
      841 gtcagatgtc tcaacaaaca cctgtcatcc cagtatttgg gaagtgcagg caggaggatc
      901 aggggttcaa ggccagcctg ggctaacagt aagtttgagg ctagccttgt ctgttacata
      961 agtaataaca ataaaaatca atcaaagtcc tgctcaggaa ttttaaattg aacgacatat
     1021 ccttcttttc tagtggtgct attttcaaat caaaaaactt tgcattggct atttgttttt
     1081 acaaacatgg ttgagtttca cacggttcct tgtgatctcc atttgggtga cccgagggtt
     1141 tgtttgagga aggtgactat aatgaaggtt agcattttct gttcaaatag ttcttgttca
     1201 ggcaaaggga aatttgagta gtatcatatg ctgtatatca tgagcattct ggggcttgga
     1261 tgttctttat attaaatact ttttaa
//
