LOCUS       NM_001163557            3808 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus PTPRF interacting protein, binding protein 2 (liprin
            beta 2) (Ppfibp2), transcript variant 2, mRNA.
ACCESSION   NM_001163557
VERSION     NM_001163557.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3808)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3808)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   3  (bases 1 to 3808)
  AUTHORS   Noben-Trauth,K., Naggert,J.K. and Nishina,P.M.
  TITLE     Cloning and expression analysis of mouse Cclp1, a new gene encoding
            a coiled-coil-like protein
  JOURNAL   Biochim Biophys Acta 1352 (2), 133-137 (1997)
   PUBMED   9199242
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL513346.17.
            
            On Feb 27, 2023 this sequence version replaced NM_001163557.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC100346.1 [ECO:0000332]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-74                AL513346.17        51514-51587
            75-171              AL513346.17        81865-81961
            172-386             AL513346.17        97669-97883
            387-479             AL513346.17        126413-126505
            480-593             AL513346.17        130511-130624
            594-725             AL513346.17        142218-142349
            726-818             AL513346.17        153431-153523
            819-930             AL513346.17        159237-159348
            931-992             AL513346.17        161287-161348
            993-1068            AL513346.17        162356-162431
            1069-1172           AL513346.17        163859-163962
            1173-1240           AL513346.17        165982-166049
            1241-1298           AL513346.17        166755-166812
            1299-1340           AL513346.17        167588-167629
            1341-1482           AL513346.17        172295-172436
            1483-1609           AL513346.17        173790-173916
            1610-1738           AL513346.17        174472-174600
            1739-1889           AL513346.17        182492-182642
            1890-2001           AL513346.17        182926-183037
            2002-2090           AL513346.17        183252-183340
            2091-2213           AL513346.17        183838-183960
            2214-2339           AL513346.17        185159-185284
            2340-2528           AL513346.17        187557-187745
            2529-2705           AL513346.17        188828-189004
            2706-2771           AL513346.17        191022-191087
            2772-3808           AL513346.17        192198-193234
FEATURES             Location/Qualifiers
     source          1..3808
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 57.21 cM"
     gene            1..3808
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /note="PTPRF interacting protein, binding protein 2
                     (liprin beta 2)"
                     /db_xref="GeneID:19024"
                     /db_xref="MGI:MGI:894649"
     exon            1..74
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     exon            75..171
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             108..2822
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /note="isoform 2 is encoded by transcript variant 2;
                     liprin-beta-2; protein tyrosine phosphatase receptor type
                     f polypeptide-interacting protein-binding protein 2;
                     coiled-coil-like protein 1; PTPRF-interacting
                     protein-binding protein 2; protein tyrosine phosphatase,
                     receptor-type, F interacting protein, binding protein 2"
                     /codon_start=1
                     /product="liprin-beta-2 isoform 2"
                     /protein_id="NP_001157029.1"
                     /db_xref="CCDS:CCDS52356.1"
                     /db_xref="GeneID:19024"
                     /db_xref="MGI:MGI:894649"
                     /translation="MTSDASHMLEAALEQMDGIIAGTKTAADFSDGTCEPGLSPPSTC
                     LNSMPVLHLIEDLRLALEMLALPQEREALLSQVPGPTATYIKEWFEDSLSQVNHHGAA
                     SNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEML
                     QQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQKEQEEKQRKAEELLQELKHLKIK
                     VEELENERNQYEWELKATKAEVAQLQEQVALKDAEIERLHSQLSRSAALHSDHAERDQ
                     EIHRLKMGMETLLVANEDKDRRIEELTGLLNKYLRVKEIVMATQGPSERTLSINEDEI
                     EGSFRKWNTTNKSPEEVPKQEISPRCSSPTPGPPPLPQKSLESRAQKKLSCSLEDLRR
                     ESGDKCVDGNQLSPVGEPKDSSFLAEQKYPTLPGKLSGATPNGEAAKSPPTASLQPDS
                     SGSSQPKLRDTEGGWEDIVSSASSGTESSPQSPVTPDGKRSPKGIKKFWGKIRRTQSG
                     NFNTDAPGMAEFRRGGLRATAGPRLSRTRDTKGQKCDANAPFAQWSTERVCTWMEDFG
                     LGQYVIFARQWVTSGHTLLTATPQDMEKELGIKHPLHRKKLVLAVKAINAKQEETSAL
                     LDHIWVTRWLDDIGLPQYKDQFHESRVDGRMLQYLTVNDLLFLKVTSQLHHLSIKCAI
                     HVLHVNKFNPNCLHRRPADESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVH
                     GGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLTTKFNALIGPEAEQEKRDKMASPAYT
                     PLTTTAKVRPRKLGFSHFGNMRKKKFDESTDYICPMEPGDAVSDSHRVYGVYRGLSPL
                     DNHELDGLDQMAPSEGTVTQIGLLSQDIHRLTTLLSQDQLLNDPPGCP"
     exon            172..386
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     exon            387..479
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     exon            480..593
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     exon            594..725
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     exon            726..818
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     exon            819..930
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     exon            931..992
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     exon            993..1068
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1069..1172
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1173..1240
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1241..1298
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1299..1340
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1341..1482
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1483..1609
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1610..1738
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1739..1889
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1890..2001
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2002..2090
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2091..2213
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2214..2339
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2340..2528
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2529..2705
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2706..2771
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2772..3808
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3124..3129
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /note="hexamer: AACAAA"
     polyA_site      3149
                     /gene="Ppfibp2"
                     /gene_synonym="Cclp1"
                     /note="major polyA site"
ORIGIN      
        1 tggagtgggc gctaggatcc ccgcatgaaa gggcaacatt gttcccatgc acggcatgtt
       61 caagctctga acagtagcag caggagacta agcagataaa aggagccatg acttctgacg
      121 ctagtcatat gctggaagct gccctggagc agatggacgg gatcattgca ggcactaaaa
      181 cagctgcaga ttttagtgat ggtacctgtg agcctgggct gtctccccca tccacctgct
      241 tgaactccat gcctgtgctc catctcattg aggacctgag actagccttg gagatgttgg
      301 cacttcctca ggaaagagaa gccctcctga gccaggtccc tggcccaaca gctacctaca
      361 taaaggagtg gtttgaggac agcttgtccc aggtaaatca ccacggtgct gctagtaatg
      421 aaacctacca ggaacgcctg gcacggctag aaggagataa agagtccctc atactacagg
      481 tgagcgtcct cacagatcaa gtggaagccc aaggagagaa gattcgggac cttgaagtgt
      541 gtctggaagg ccaccaggtg aagctcaatg ctgcagaaga gatgcttcag caggagctgc
      601 taagtcgcac atctctggag acccagaagt tggatctgat gactgaggtg tctgagctga
      661 agctcaagct ggttggtatg gaaaaagaac agaaagaaca agaagaaaaa cagagaaaag
      721 cagaggagtt actgcaagag cttaagcacc tcaaaatcaa ggtggaggag ctggagaacg
      781 agcggaacca gtatgagtgg gagctgaagg ccaccaaggc tgaggtagcc cagctgcaag
      841 aacaggtggc cctaaaagat gcagaaattg agcgtctcca cagccagctc tcccggagtg
      901 cagctctcca cagcgaccat gcagagcgag atcaagaaat ccaccgtctg aaaatgggga
      961 tggaaacact gctggttgcc aatgaggata aggaccgtcg gatagaggag ctgacagggc
     1021 tgttgaacaa gtacctaagg gtaaaggaga ttgtgatggc aactcagggg ccttcagaaa
     1081 gaaccctctc catcaatgaa gatgaaatag agggaagctt ccgaaaatgg aataccacaa
     1141 ataaaagccc agaggaagtc ccgaagcaag agatatcacc acgatgcagc tctcccaccc
     1201 caggaccacc tcctttgcca cagaaatcac tggagagcag ggctcagaag aaactctcct
     1261 gcagtctaga agacttgaga cgtgaatctg gggataagtg tgtcgatggg aaccagctgt
     1321 ccccagtggg agagcccaag gacagctctt tcctagcgga gcagaaatac cccacattac
     1381 ctgggaagct ttcaggagcc acacccaatg gagaagctgc caaatctcct cccactgcct
     1441 ccctccagcc tgactcttca gggagcagcc agccaaagct gagagacaca gaaggaggct
     1501 gggaagatat agtctcatct gcttcgtctg ggactgagtc aagccctcag tctcccgtga
     1561 caccagatgg caaacggagc cccaaaggca ttaagaagtt ctggggaaag atccgaagaa
     1621 ctcagtctgg aaacttcaat actgatgcac cggggatggc agagtttcga cgaggtgggc
     1681 tccgagcaac tgcgggacca aggctttcta ggaccaggga caccaaggga cagaaatgtg
     1741 atgccaatgc cccctttgcc cagtggagca cagaacgcgt atgtacatgg atggaggatt
     1801 tcggcctggg tcagtatgtg atctttgcca gacagtgggt gacatctgga catacactac
     1861 tgacagctac ccctcaggac atggaaaagg agctagggat taaacacccc ctccacagga
     1921 agaagctggt tttagcagtg aaagctatca acgccaagca agaagaaacg tctgcgctgc
     1981 tggaccacat ttgggtgaca cggtggcttg atgatattgg cttaccccaa tacaaagacc
     2041 agtttcatga atcaagagtt gatgggcgaa tgctgcaata cctaactgtg aatgatctac
     2101 tcttcttaaa agtcaccagc caactacatc atctcagcat caaatgtgct attcacgtgc
     2161 tacatgtcaa caagttcaac cccaactgcc tgcacaggag gcctgctgat gagagtaacc
     2221 tttccccttc cgaagttgtg cagtggtcca accacagggt aatggagtgg ctgcgatccg
     2281 tggacctggc agagtatgca cccaaccttc gagggagtgg cgtccatggc ggcctcatta
     2341 tcctggagcc tcgctttact ggggacaccc tggctatgct tcttaacatc cccccacaga
     2401 agacgctcct caggcgccat ctgaccacca agttcaacgc cctgattggt cctgaggctg
     2461 aacaggaaaa gcgagacaaa atggcctcac ccgcctacac acctctgacc accaccgcca
     2521 aagttcggcc taggaaactt ggattttcac attttggaaa catgagaaaa aagaagtttg
     2581 atgaatctac agattacatt tgccccatgg agcctggaga tgctgtcagt gacagccaca
     2641 gggtctacgg agtctaccgg ggcctcagtc cccttgacaa ccatgaacta gatggtttgg
     2701 accagatggc accttccgaa ggcactgtga cacagatagg gctcctctcc caagacatcc
     2761 accgcctcac gactctactg agccaggacc aactcctgaa tgacccgcct ggctgtccct
     2821 gatgctggtg actacagatg acattcttca tggctgagag cctagagagg cacacgtgga
     2881 gccccaatgt tcacctcaat ggggagttgg cacagagcca ccaagagatg gagcttatgg
     2941 gcctctttgg atgtaggcgt tgaccggagc aaaagcagag gggtgggaca ggtgtccagt
     3001 cgtgtccccg cgtttccctg tgttgtcagc gcttgctttc cactgcaact tttctacctt
     3061 ttgtactttt atatgccaac tgcagctgat cctgcagagg tgaaggtgag gtggtaaatg
     3121 cagaacaaag acaatgagct gttagttcat gaaagcctgt gattggaggt ggggaaaggt
     3181 tgtataagct gttctgtgtg tcctgcagtg gctgagtgaa atgatttggg ggaggggtag
     3241 tggaccctct ggggcagctt catagaagta tgcatgtcca cttccagaag cctgggcctg
     3301 tgaatcagga ctctcctctt gatcccccaa cagctttcat ctaccctcat tccaagacac
     3361 acatttcccc ctcacctgcc tcaagtacag tgtctggtca aacaccgccc cctagtggac
     3421 tgtctctaaa ctcaaacttc attgtttttt cctgttgtgt ctcatacaag ccagttccct
     3481 cccaggccat gactgttcta gttccagcct tgctgtctga tcgctgctcc tggttttcta
     3541 cttggtccct cactttccta gatgatccct gccaaccatt ctccacttct gtcacctagt
     3601 cacatttctg ctttgaattc ctttgaatgc cacctttcca ccatcatgcc aacctttgtg
     3661 agtccaccga tttgtgtttg cttcacttcc tttattcttt cttttggttc caaatccact
     3721 ttgcccttca gcattgtatg cctctgagat gttcacagtt cactttaagg ttatatgcac
     3781 atgtgtaccc gatacacaaa ccagctga
//
