LOCUS       NM_001374777            6080 bp    mRNA    linear   ROD 26-NOV-2024
DEFINITION  Mus musculus protein tyrosine phosphatase, receptor type, f
            polypeptide (PTPRF), interacting protein (liprin), alpha 4
            (Ppfia4), transcript variant 2, mRNA.
ACCESSION   NM_001374777 XM_006529847
VERSION     NM_001374777.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6080)
  AUTHORS   Emperador-Melero,J., Andersen,J.W., Metzbower,S.R., Levy,A.D.,
            Dharmasri,P.A., de Nola,G., Blanpied,T.A. and Kaeser,P.S.
  TITLE     Distinct active zone protein machineries mediate Ca2+ channel
            clustering and vesicle priming at hippocampal synapses
  JOURNAL   Nat Neurosci 27 (9), 1680-1694 (2024)
   PUBMED   39160372
REFERENCE   2  (bases 1 to 6080)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 6080)
  AUTHORS   Guo,P., Lim,R.C., Rajawasam,K., Trinh,T., Sun,H. and Zhang,H.
  TITLE     A methylation-phosphorylation switch controls EZH2 stability and
            hematopoiesis
  JOURNAL   Elife 13, e86168 (2024)
   PUBMED   38346162
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6080)
  AUTHORS   Kherraf,Z.E., Conne,B., Amiri-Yekta,A., Kent,M.C., Coutton,C.,
            Escoffier,J., Nef,S., Arnoult,C. and Ray,P.F.
  TITLE     Creation of knock out and knock in mice by CRISPR/Cas9 to validate
            candidate genes for human male infertility, interest, difficulties
            and feasibility
  JOURNAL   Mol Cell Endocrinol 468, 70-80 (2018)
   PUBMED   29522859
REFERENCE   5  (bases 1 to 6080)
  AUTHORS   Wentzel,C., Sommer,J.E., Nair,R., Stiefvater,A., Sibarita,J.B. and
            Scheiffele,P.
  TITLE     mSYD1A, a mammalian synapse-defective-1 protein, regulates
            synaptogenic signaling and vesicle docking
  JOURNAL   Neuron 78 (6), 1012-1023 (2013)
   PUBMED   23791195
REFERENCE   6  (bases 1 to 6080)
  AUTHORS   Spangler,S.A., Jaarsma,D., De Graaff,E., Wulf,P.S., Akhmanova,A.
            and Hoogenraad,C.C.
  TITLE     Differential expression of liprin-alpha family proteins in the
            brain suggests functional diversification
  JOURNAL   J Comp Neurol 519 (15), 3040-3060 (2011)
   PUBMED   21618222
REFERENCE   7  (bases 1 to 6080)
  AUTHORS   Zurner,M., Mittelstaedt,T., tom Dieck,S., Becker,A. and Schoch,S.
  TITLE     Analyses of the spatiotemporal expression and subcellular
            localization of liprin-alpha proteins
  JOURNAL   J Comp Neurol 519 (15), 3019-3039 (2011)
   PUBMED   21618221
REFERENCE   8  (bases 1 to 6080)
  AUTHORS   Zurner,M. and Schoch,S.
  TITLE     The mouse and human Liprin-alpha family of scaffolding proteins:
            genomic organization, expression profiling and regulation by
            alternative splicing
  JOURNAL   Genomics 93 (3), 243-253 (2009)
   PUBMED   19013515
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124110.8.
            
            On Oct 15, 2019 this sequence version replaced XM_006529847.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.7058.1,
                                           SRR7652917.611400.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-124               AC124110.8         17953-18076
            125-763             AC124110.8         29741-30379
            764-865             AC124110.8         33422-33523
            866-1030            AC124110.8         33861-34025
            1031-1105           AC124110.8         34302-34376
            1106-1195           AC124110.8         34580-34669
            1196-1387           AC124110.8         35220-35411
            1388-1534           AC124110.8         35707-35853
            1535-1669           AC124110.8         36051-36185
            1670-1753           AC124110.8         38075-38158
            1754-1885           AC124110.8         38459-38590
            1886-1977           AC124110.8         39576-39667
            1978-2086           AC124110.8         41500-41608
            2087-2295           AC124110.8         43246-43454
            2296-2536           AC124110.8         44621-44861
            2537-2572           AC124110.8         45196-45231
            2573-2706           AC124110.8         45473-45606
            2707-2870           AC124110.8         45891-46054
            2871-2964           AC124110.8         48946-49039
            2965-3046           AC124110.8         49501-49582
            3047-3247           AC124110.8         49933-50133
            3248-3310           AC124110.8         50550-50612
            3311-3337           AC124110.8         51114-51140
            3338-3513           AC124110.8         52918-53093
            3514-3611           AC124110.8         58285-58382
            3612-3787           AC124110.8         58889-59064
            3788-3856           AC124110.8         62131-62199
            3857-4034           AC124110.8         63201-63378
            4035-6080           AC124110.8         63841-65886
FEATURES             Location/Qualifiers
     source          1..6080
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 58.18 cM"
     gene            1..6080
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /note="protein tyrosine phosphatase, receptor type, f
                     polypeptide (PTPRF), interacting protein (liprin), alpha
                     4"
                     /db_xref="GeneID:68507"
                     /db_xref="MGI:MGI:1915757"
     exon            1..124
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            125..763
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     CDS             530..4084
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /note="isoform 2 is encoded by transcript variant 2;
                     Liprin-alpha4"
                     /codon_start=1
                     /product="liprin-alpha-4 isoform 2"
                     /protein_id="NP_001361706.1"
                     /db_xref="CCDS:CCDS87879.1"
                     /db_xref="GeneID:68507"
                     /db_xref="MGI:MGI:1915757"
                     /translation="MCEVMPTINEGDPLGPPHGADAEANFEQLMVNMLDEREKLLESL
                     RESQETLVATQSRLQDALHERDQLQRHLNSALPQEFATLTRELSMCREQLLEREEEIS
                     ELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEH
                     HKALDEKVRERLRAALERVTTLEEQLAGAHQQVSALQQGAGIRDGVAEEEGTVDLGPK
                     RLWKDDTGRVEELQGLLEKQNYELSQARERLVTLSATVTELEEDLGTARRDLIKSEEL
                     SSKHQRDLREALAQKEDMEERITTLEKRYLAAQREATSIHDLNDKLENELANKESLHR
                     QCEEKARHLQELLEVAEQKLQQTMRKAETLPEVEAELSQRIAALTKAEERHGNIEEHL
                     RQLEGQLEEKNQELARVRQREKMNEDHNKRLSDTVDRLLSESNERLQLHLKERMAALE
                     EKGRLSEEIEKLRQEVDQLKGRGGPFVDGIHSRSHVGSAADVRFSLSTATHAPPGLHR
                     RYSALRDESAKDWKPSPLPGVLGATTPAFDSDPEISDVDEDEPGGLVGTQVDVISPGG
                     HSDAQTLAMMLQEQLDAINQEIRMIQEEKESTELRAEEIETRVTSGSMEALNLTQLRK
                     RGSIPTSLTALSLASASPPLSGRSTPKLTSRSAAQDLDRMGVMTLPSDLRKHRRKLLS
                     PVSREENREDKATIKCETSPPSSPRTLRLEKLGHPGLSQEEGKSALEGQDSNPSSSNS
                     SQDSLHKGAKRKGIKSSIGRLFGKKEKGRLIQLSRDATGHVLLTDSELSLQEPMVPAK
                     LGTQAEKDRRLKKKHQLLEDARRKGMPFAQWDGPTVVSWLELWVGMPAWYVAACRANV
                     KSGAIMSALSDTEIQREIGISNALHRLKLRLAIQEMVSLTSPSAPPTSRTSSGNVWVT
                     HEEMETLATSTKTDSEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDA
                     RMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELEKRREESQHEIKDVL
                     VWTNDQVVHWVQSIGLRDYAGNLHESGVHGALLALDENFDHNTLALVLQIPTQSTQAR
                     QVMEREFNNLLALGTDRKLDDGEEKVFRRAPSWRKRFRPRDHHSGGMLGTSAETLPAG
                     FRVSTLGPLQPPPAPPKKIMPEAHSHYLYGHMLSAFRD"
     exon            764..865
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            866..1030
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            1031..1105
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            1106..1195
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            1196..1387
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            1388..1534
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            1535..1669
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            1670..1753
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            1754..1885
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            1886..1977
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            1978..2086
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            2087..2295
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            2296..2536
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            2537..2572
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            2573..2706
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            2707..2870
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            2871..2964
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            2965..3046
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            3047..3247
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            3248..3310
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            3311..3337
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            3338..3513
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            3514..3611
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            3612..3787
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            3788..3856
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            3857..4034
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     exon            4035..6080
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4465..4470
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /note="hexamer: AATAAA"
     polyA_site      4488
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /note="major polyA site"
     regulatory      6052..6057
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /note="hexamer: AATAAA"
     polyA_site      6080
                     /gene="Ppfia4"
                     /gene_synonym="100042382; 1110008G13Rik; Gm3812"
                     /note="major polyA site"
ORIGIN      
        1 gaggccacgg tactgggcgg tggaggctgc agctaccttt gcaggcttgc ctctaggacg
       61 cctcgcgctg ccgaggtcgg gggcggcgcc ctgctaccgc tgggccttcg gcgattccac
      121 gcagaccaca ccgccctcca gaaaccatgg gtgttgctag acccagctgg gattctgcca
      181 agctctggtg ctcagtctaa gacaagggct gccttccagc cctgttcgcc cagcctgtca
      241 tggccacaca ccgatgcctc ccgcttgtgt ggggacacag ggcacccagc cccaaccctg
      301 aaaggttaag ccaggccttc tggctccatt ccacagggac actgcaggcc cgaggctcct
      361 ttcagagcaa gagcaactga tgtcatggga gaagccccta cccaactgtc cacttgcctg
      421 gcactgcctg ttctgagacc cacgccctgg gtccttctgc aggtgccaac cccgtgagct
      481 ccctcccacc ccctgacccg acgctgagaa ggctctctcc attcccatca tgtgtgaggt
      541 gatgcccaca atcaatgagg gggaccccct ggggcccccc cacggtgccg atgctgaggc
      601 caactttgag cagctgatgg tgaacatgct ggatgagcga gagaagttgc tggagtccct
      661 tcgggagagt caggaaactt tggtagccac acagagccgg ctccaggatg cccttcacga
      721 gcgagatcag ctccagcgcc acctgaactc cgcccttccc caggaatttg ccactttaac
      781 tcgggagcta agcatgtgtc gggagcagct tctggagcgg gaggaagaga tatctgagct
      841 gaaagcagag cggaataaca caaggctgct tctggaacat ctggaatgcc tcgtgtcccg
      901 ccatgagcgg tcattgcgga tgacagtggt aaaacggcag gcccaatcac cttcaggtgt
      961 ctccagtgag gtggaggtgc tgaaggccct caagtcacta tttgagcacc acaaggccct
     1021 ggatgagaag gtgcgagagc ggctccgggc agctctagag cgcgttacta ccttggagga
     1081 gcagttggca ggagctcacc agcaggtatc tgccctgcag cagggtgcag gaattcggga
     1141 tggagtagca gaagaggaag ggactgtgga tctgggacca aaacgcctgt ggaaagatga
     1201 cactggccgc gtggaagagc tgcaaggact cttggagaag caaaactatg agttgagcca
     1261 ggcccgtgag cggctggtca ccctgagtgc caccgtgact gagctggagg aggacctggg
     1321 cacggcccgc cgagacctca tcaagtcaga ggagctgagc agcaagcatc agcgggacct
     1381 ccgagaggct ctggctcaga aggaggacat ggaagagaga atcaccacac tggagaagcg
     1441 ctacttggct gctcagcgag aagccacatc catccatgac ctcaatgaca aactggagaa
     1501 tgagctggcc aacaaggaat ccctgcaccg ccagtgtgag gagaaagccc ggcatctgca
     1561 ggagctgcta gaagtagcag agcagaagtt gcagcagacc atgcgcaagg cagagactct
     1621 gcccgaggtg gaggctgagc tgtctcagag aatcgcagcc ctcaccaagg ctgaggaacg
     1681 tcatggcaac attgaggaac atctgcggca gctggaaggg cagctggaag agaagaacca
     1741 ggagctggca agggtgcgcc agcgggagaa gatgaatgaa gaccacaaca agcggctgtc
     1801 agacaccgtg gaccggttgc ttagtgagtc caacgaacgc ctgcagctcc acctcaagga
     1861 gcgaatggct gccctggagg agaagggccg tctgtctgaa gagattgaga agctgcgcca
     1921 agaggtggac cagctgaagg gtcgaggggg gccgtttgtg gatggcatcc actccaggtc
     1981 acacgtgggc agcgcagcag atgtgaggtt ctcactgagt acagccacac acgcgccccc
     2041 aggtctgcat cgacgctatt cggcgctgag ggatgaatct gccaaggact ggaagccatc
     2101 gccactgcca ggggtgttgg gcgccaccac gcctgccttt gacagtgacc ctgagatctc
     2161 tgatgtggat gaggatgagc ctgggggctt ggtgggcact caggtcgatg tcatctcacc
     2221 cggtggccat tcagatgccc agaccctggc catgatgcta caggagcagc tggatgccat
     2281 caaccaggag atcaggatga tccaggagga gaaggagtcc actgagcttc gagctgagga
     2341 gattgagacc cgtgtgacca gcggcagcat ggaggccctc aacctgaccc agctgcgcaa
     2401 gcgtggctct atccccacct ctctgaccgc cctttccctg gccagtgcat ctccaccgct
     2461 cagtggccgc tccacaccca agctcacttc ccgaagtgct gcccaggatc tggaccgaat
     2521 gggggtcatg accctgccca gcgacttaag aaagcatagg aggaagctgc tgtcgccagt
     2581 gtctcgggaa gagaaccgag aggataaagc caccataaaa tgtgagactt ctcctccttc
     2641 ctcacccagg acgctgcggc tagagaagct tggccaccct ggcctgagtc aagaggaggg
     2701 caagagtgcc ttggagggtc aggacagcaa ccccagcagc agcaacagca gccaggactc
     2761 cctgcacaag ggcgccaagc gcaagggcat caagtcatcc attggccgcc tgtttgggaa
     2821 gaaggagaag ggcaggctga tccagctgag tcgggatgcc acgggccatg ttctgctcac
     2881 agactccgag ctcagtctgc aggaaccaat ggtacctgct aagttgggga cccaggcaga
     2941 gaaggaccgg cgactgaaaa agaaacacca gctgcttgaa gatgcgcgcc gaaaaggaat
     3001 gccctttgcc caatgggatg gccccacggt ggtctcctgg ctggagctct gggtggggat
     3061 gcctgcctgg tatgtggcgg cctgccgggc caatgtcaag agtggcgcca tcatgtccgc
     3121 cttgtcggac acggagatcc agcgggagat cggcatcagc aatgccctgc acaggctcaa
     3181 gctccgcctg gccatccagg agatggtgtc actgacgagc ccctcagctc cacctacctc
     3241 caggacttct tcagggaatg tctgggtgac ccacgaagag atggaaactc tggcaacatc
     3301 taccaaaaca gacagtgagg agggcagctg ggcccagacc ctggcctatg gagacatgaa
     3361 tcacgagtgg attggaaacg aatggctgcc cagcctgggg ctccctcagt accgtagtta
     3421 cttcatggag tgcctggtgg atgcccgcat gctggatcac ctcaccaaga aggacctgcg
     3481 tgtccatctc aagatggtgg acagtttcca tagaaccagt cttcagtatg gcatcatgtg
     3541 tctgaagagg ctgaattatg accggaagga actggaaaag aggcgggaag agagccagca
     3601 tgagatcaag gatgtgctgg tctggaccaa tgaccaggtg gttcactggg tccagtctat
     3661 agggctaagg gactatgcag gaaacctaca cgagagtggt gtgcatggcg ccctgctggc
     3721 cctggatgaa aacttcgacc acaacacact ggccttggtt ctgcagatcc ccacacagag
     3781 cacccaggcc cgccaagtga tggagagaga gttcaataac ctgttggcct tgggcacaga
     3841 caggaaattg gatgacggag aagagaaggt gttccgccga gcaccctcct ggaggaaacg
     3901 cttccggcct cgggatcacc atagcggtgg catgttgggc acctcagcgg agaccctccc
     3961 ggcgggcttc cgtgtgtcca cgctgggtcc gctgcagcct ccacctgccc cgcctaagaa
     4021 gatcatgccg gaagctcact cccactatct ctacggacac atgctctccg ccttccggga
     4081 ctagccacgg cccccagggc gggtgtcctg gtttcacagg ctcagccggc cctgaccctt
     4141 cctgctcgtt ccctttctcc cttggctccc agtctctcct ctgtgatttt ccagttgccc
     4201 gggatctcag aatatgctca tccactcctt catcatccca ctatccgagt cctacttcgt
     4261 tccccctttg taagtctctg gaggatgtga ccaaggtctc ccgtgagtgt ctgtcgggca
     4321 cccaggttgt aggtgtttga gattctgtag gagggaggga aggacagcac ctgtggccac
     4381 cttccctctt ccggatctgt tttggtctgg actatgggct catcaggccc aggatcccgg
     4441 accaaagact gagatgaccc ttccaataaa aggccatttc ggactctgtc ctgcttggac
     4501 taattggcct tctggacccc tccactctgg ccgtacccga tggtctgagt ggttttgcca
     4561 cctcctctct cagtatcact ccctcctccc caaaccccaa tctccagtgt ctgtagctct
     4621 tgcctgcaag tcttgcttgt ggggtgacga ggggtgtaga ataccccgaa ccctcttcca
     4681 ggacaaagcc aggagtggag ctgaggaaga ctaaggtaga aactctgtgc ccaagctgac
     4741 acagaacccc aaatgtgtgg gaggaatgga ccccagagct ttgggcccag ggtgagggca
     4801 aggggaactc ttcagcccct tgcctagaga gatggcctga tggccttttg tgcttccccc
     4861 cagagggcag tggggatgcc tccagcccca gccccaaatg gtgctgctac tggatcagat
     4921 tgtgaacggt taactctgcc ctgaagtggg ggtgcgggaa tggggaggct tcccctttag
     4981 tgactcatgt cccaggtcta agaaatctaa agtggactga ggcaggctcc cttgtgtgtc
     5041 cctataccct ccagccctcc tttagggttc ttttgggggt aaggggctaa ctgctcaaga
     5101 aaatcttgat cccctctctt gtctccatta ttttaattgc tttttctggc agcacggtgg
     5161 ggacagggca gatttatgag aaatatcaat tgcccctctc ttctggacca attccttaac
     5221 cttgggaaag ctcagggcct agtatcaggg tgggtgatag aacccgaaat ggaagaggac
     5281 gggaaagtgc ctgggctgtg cttgtgaccg gcagtacagt gccatcctgg aggtgactgg
     5341 agtagctgct ttgccatttc atcactggga ttctgaacag gcgccaagct aacaggtgga
     5401 gaaatgagcc agaactccct gtctgaaaag gatgccgagc cttgtgctca gcagagggaa
     5461 gtttggctaa tgggctgatc gaatgagcta acatgggctg gggcaggcaa ctacccgtcc
     5521 tcaagcccgc tgtttctgtc tccctaccag acaggcctct gggaatggag agagaagcag
     5581 ctgagtagaa catgaactag ttagagcgag agaacccttg gtcctgaata gtggagttat
     5641 agagaagggc cagtcctaag atggaaggag ccctacaatc tgactccttc tagggactct
     5701 ggggctagct ttgtgggaga gtcagccctg cccctcctct cccatgtgac cctgtcatag
     5761 tttgcagtgt cctaggtagc acttggggag ccaggtgcat tcagggtcag tagggaggac
     5821 aaaatagggg gctctacgtg cagtgaggaa aggctgctgt catggtgtgg ccctgcctca
     5881 ctgtcaatat ctgttttctc tggagagtcc accagtgacc caagctctcc ctgccagcct
     5941 cctgtgtcaa accaggtccc ttctcagtac tgtattggct cagtgctttc aggagtgagt
     6001 gtgtgagtga gtgtgtgagt gtgtgtgggc gtgagcgggt gtgtacgtac caataaacat
     6061 cctggtttta agacaatgta
//
