LOCUS       NM_001205341            6454 bp    mRNA    linear   ROD 26-NOV-2024
DEFINITION  Mus musculus protein tyrosine phosphatase, receptor type, f
            polypeptide (PTPRF), interacting protein (liprin), alpha 2
            (Ppfia2), transcript variant 1, mRNA.
ACCESSION   NM_001205341
VERSION     NM_001205341.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6454)
  AUTHORS   Emperador-Melero,J., Andersen,J.W., Metzbower,S.R., Levy,A.D.,
            Dharmasri,P.A., de Nola,G., Blanpied,T.A. and Kaeser,P.S.
  TITLE     Distinct active zone protein machineries mediate Ca2+ channel
            clustering and vesicle priming at hippocampal synapses
  JOURNAL   Nat Neurosci 27 (9), 1680-1694 (2024)
   PUBMED   39160372
REFERENCE   2  (bases 1 to 6454)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 6454)
  AUTHORS   Banerjee,A., Imig,C., Balakrishnan,K., Kershberg,L., Lipstein,N.,
            Uronen,R.L., Wang,J., Cai,X., Benseler,F., Rhee,J.S., Cooper,B.H.,
            Liu,C., Wojcik,S.M., Brose,N. and Kaeser,P.S.
  TITLE     Molecular and functional architecture of striatal dopamine release
            sites
  JOURNAL   Neuron 110 (2), 248-265 (2022)
   PUBMED   34767769
REFERENCE   4  (bases 1 to 6454)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6454)
  AUTHORS   Emperador-Melero,J., Wong,M.Y., Wang,S.S.H., de Nola,G.,
            Nyitrai,H., Kirchhausen,T. and Kaeser,P.S.
  TITLE     PKC-phosphorylation of Liprin-alpha3 triggers phase separation and
            controls presynaptic active zone structure
  JOURNAL   Nat Commun 12 (1), 3057 (2021)
   PUBMED   34031393
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6454)
  AUTHORS   Wentzel,C., Sommer,J.E., Nair,R., Stiefvater,A., Sibarita,J.B. and
            Scheiffele,P.
  TITLE     mSYD1A, a mammalian synapse-defective-1 protein, regulates
            synaptogenic signaling and vesicle docking
  JOURNAL   Neuron 78 (6), 1012-1023 (2013)
   PUBMED   23791195
REFERENCE   7  (bases 1 to 6454)
  AUTHORS   Zurner,M., Mittelstaedt,T., tom Dieck,S., Becker,A. and Schoch,S.
  TITLE     Analyses of the spatiotemporal expression and subcellular
            localization of liprin-alpha proteins
  JOURNAL   J Comp Neurol 519 (15), 3019-3039 (2011)
   PUBMED   21618221
REFERENCE   8  (bases 1 to 6454)
  AUTHORS   Zurner,M. and Schoch,S.
  TITLE     The mouse and human Liprin-alpha family of scaffolding proteins:
            genomic organization, expression profiling and regulation by
            alternative splicing
  JOURNAL   Genomics 93 (3), 243-253 (2009)
   PUBMED   19013515
REFERENCE   9  (bases 1 to 6454)
  AUTHORS   Samuels,B.A., Hsueh,Y.P., Shu,T., Liang,H., Tseng,H.C., Hong,C.J.,
            Su,S.C., Volker,J., Neve,R.L., Yue,D.T. and Tsai,L.H.
  TITLE     Cdk5 promotes synaptogenesis by regulating the subcellular
            distribution of the MAGUK family member CASK
  JOURNAL   Neuron 56 (5), 823-837 (2007)
   PUBMED   18054859
REFERENCE   10 (bases 1 to 6454)
  AUTHORS   Olsen,O., Moore,K.A., Fukata,M., Kazuta,T., Trinidad,J.C.,
            Kauer,F.W., Streuli,M., Misawa,H., Burlingame,A.L., Nicoll,R.A. and
            Bredt,D.S.
  TITLE     Neurotransmitter release regulated by a MALS-liprin-alpha
            presynaptic complex
  JOURNAL   J Cell Biol 170 (7), 1127-1134 (2005)
   PUBMED   16186258
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC140785.4, EU568870.1 and CD802610.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EU568870.1, AK220491.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-29                AC140785.4         120351-120379
            30-6415             EU568870.1         1-6386
            6416-6454           CD802610.1         1-39                c
FEATURES             Location/Qualifiers
     source          1..6454
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 55.39 cM"
     gene            1..6454
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /note="protein tyrosine phosphatase, receptor type, f
                     polypeptide (PTPRF), interacting protein (liprin), alpha
                     2"
                     /db_xref="GeneID:327814"
                     /db_xref="MGI:MGI:2443834"
     exon            1..282
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            283..533
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            534..587
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            588..689
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            690..854
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            855..929
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            930..1046
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            1047..1268
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            1269..1415
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            1416..1550
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            1551..1634
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            1635..1766
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            1767..1829
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            1830..1921
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            1922..2057
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            2058..2278
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            2279..2516
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            2517..2546
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            2547..2677
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            2678..2832
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            2833..2926
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            2927..3008
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            3009..3209
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            3210..3272
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            3273..3302
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            3303..3496
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            3497..3594
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            3595..3770
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            3771..3839
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            3840..3999
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            4000..4091
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     exon            4092..6437
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5462..5467
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /note="hexamer: AATAAA"
     polyA_site      5483
                     /gene="Ppfia2"
                     /gene_synonym="5330438O12; B230207K17Rik; E130120L08Rik;
                     mKIAA4112"
                     /note="major polyA site"
ORIGIN      
        1 tgcttcccaa agcaaaattt gtaatatgcc atttttccga tggacctttc tccttttggc
       61 tgctgacgga gccacgggaa gatgccgaac tgctgccacg ttaggaagcc agggcacgtt
      121 ccaagagaac gctggggctc gcgagtgtct aagctgtctt tctcctcccg ttgctaagga
      181 aatggtccag gactgctggg tgtgagcctc acctctcctc cagccgagac tgcggttgtc
      241 attgacaatt gaagaaacag gacctgaaat aagagacatt agcaatgatg tgtgaagtga
      301 tgcccacgat taacgaggac accccaatga gccaacgggg ttcccaaagc agtggctccg
      361 actcggactc ccattttgag caactcatgg tcaatatgct ggatgaaagg gaccgcctac
      421 tggacacact ccgagagacc caggagagcc tctcacttgc ccagcaaagg ctccaggatg
      481 tcatctatga cagagattca ctccagagac agctgaattc agccctacct caggacatcg
      541 aatccctaac aggagggctg actggttcta agggggctga tccaccggag tttgctgcac
      601 tgactaaaga gttgaatgct tgccgtgaac aacttctaga aaaggaagaa gaaatctcag
      661 agctgaaagc cgaaagaaac aacacaagac tgttactgga acacttggag tgccttgtgt
      721 cccgacatga acggtcacta agaatgacgg tggtcaagcg gcaagcccag tctccctctg
      781 gagtgtccag tgaagtggag gttctcaagg cactgaaatc tttgtttgaa caccacaaag
      841 ccttggatga aaaggtaagg gagcgactga gggtttcttt agaaagagtc tctgcactgg
      901 aagaggaact agctgcagct aatcaggaga ttgttgcctt gcgtgagcaa aatgttcata
      961 ttcaaaggaa aatggtatca agtgaggggt ccacggagtc agagcatctt gaaggaatgg
     1021 aagcaggcca gaaagttcat gaaaagcgtc tatccaatgg ctccatagat tcgacagatg
     1081 acaccagcca aatcgtcgag ctgcaagaat tgcttgagaa gcaaaactat gaaatggccc
     1141 aaatgaaaga acgcttaaca gctctctctt cccgggtggg agaggtggaa caagaagcag
     1201 agacagcaag aaaggacctc attaaaacag aagaaatgaa cacaaaatat caaagggaca
     1261 tccgagaggc catggctcag aaggaagata tggaagaaag aatcacaact ctggagaagc
     1321 gttacctgag tgctcagaga gaatctacct ccattcatga tatgaatgat aaactagaaa
     1381 atgaattggc gaacaaggaa gccatcttgc ggcagatgga agaaaaaaac aggcaattgc
     1441 aagagcgtct tgaactggct gagcaaaagt tacagcagac catgagaaaa gctgaaactt
     1501 tacctgaagt agaggctgaa cttgctcaga gaattgcagc cctaacaaag gctgaagaga
     1561 ggcatggaaa tattgaagaa cgtatgagac acctcgaggg ccaacttgaa gagaagaatc
     1621 aagaacttca aagagctaga caaagggaga aaatgaatga agagcataat aagagattat
     1681 cggatacggt ggacaggctt ctgacagaat ccaatgagcg cctgcaacta cacctgaagg
     1741 aaaggatggc tgctttggaa gagaagaatg ttttgattca agaatcagaa aacttcagaa
     1801 aaaatcttga agagtcctta catgataagg aaagattagc agaagaaatc gagaagctga
     1861 ggtctgaact tgatcaaatg aaaatgagaa caggttctct aattgaaccc actatatcaa
     1921 gaactcatat agacacctcc actgagttgc ggtattcagt tgggtccctt gtagacagcc
     1981 agtctgatta cagaaccact aaagtaatac gaagaccaag gagaggccgc atgggtgtgc
     2041 gaagagatga accaaaggtg aaatcccttg gagatcatga gtggaacaga actcagcaaa
     2101 ttggagtact aggaagccac cctttcgaaa gtgacactga aatgtctgat attgatgatg
     2161 atgacagaga aacaattttt agctcaatgg atcttctctc tccaagtggc cattctgatg
     2221 cccagactct agctatgatg cttcaagaac aattggatgc aatcaataaa gaaataagac
     2281 taattcaaga agaaaaggaa tcgacagaat tgcgtgctga agaaattgag aatagagtgg
     2341 ctagtgtaag cttagaaggg ctgaatttgg cgagggtcca tccaggtacc tccatcactg
     2401 cctctgttac agcttcatca ctggccagtt catctccccc aagtggacac tcaacgccaa
     2461 agcttacacc aagaagccct gccagggaaa tggaccgcat gggagtgatg accctgccaa
     2521 gtgatctaag gaaacatcgg agaaagattg cagtggtgga agaagatgga cgggaggata
     2581 aagccacaat taaatgcgag acttctcctc ccccaacacc cagagccgtc agaatgactc
     2641 acaccttacc atcttcctac cacaatgatg cccggagcag tttatctgcc tctcttgagc
     2701 cagacagtct tgggcttggc agtgccaata gcagccaaga ttctctccac aaagccccca
     2761 agaagaaagg aatcaagtct tcaattgggc gcttatttgg gaaaaaagag aaggctcgac
     2821 tcgggcagct tcgaggcttc atggagacag aagctgcagc acaggaatcc ctgggcttag
     2881 gcaaacttgg aactcaagct gaaaaggaca gaaggctgaa gaaaaagcat gaacttcttg
     2941 aagaagctcg tagaaaagga ttaccttttg cccagtggga tggacccacc gtggttgcgt
     3001 ggctggagct ctggctggga atgccagctt ggtacgtggc agcatgcaga gccaacgtga
     3061 aaagtggtgc catcatgtca gcgttatcgg acactgaaat ccaaagggag attggaatca
     3121 gcaaccctct gcaccgctta aagctcaggc tagctatcca agagatggtt tctctcacca
     3181 gcccttcagc gcctccgaca tcgcgtactc cttcaggcaa tgtgtgggtg acccatgaag
     3241 aaatggaaaa tctgacagct ccagcaaaaa cgaaagaatc tgaggaagga agctgggccc
     3301 agtgtccggt ttttctacag accctggctt atggagatat gaaccacgag tggattggaa
     3361 atgaatggct tcccagcctg gggttacctc aatacagaag ttactttatg gaatgcttgg
     3421 ttgatgcaag aatgttagac cacctcacaa aaaaggatct tcgtgtccat ttaaaaatgg
     3481 tggatagttt ccatcgaaca agtttacagt atggaattat gtgcttgaaa agattgaatt
     3541 atgacagaaa agaactagag agaagacgag aagcaagtca acatgaaata aaagatgttt
     3601 tagtgtggag caatgatcga gttattcgct ggatacaagc aattggactt cgggaatatg
     3661 caaacaacat tcttgagagt ggcgtgcatg gctcacttat agccctggat gagaactttg
     3721 actacagcag cttggctcta ttgttgcaga ttccaacaca gaacacccag gcaaggcaga
     3781 ttcttgaacg tgagtacaac aacctcttgg ccctgggaac tgagcggaga ctggatgaaa
     3841 gtgacgacaa gaatttcaga cggggatcaa cctggcgaag gcagttccct cctcgtgaag
     3901 ttcatggaat cagcatgatg cctgggtcct cagaaacatt accagctgga ttcaggttga
     3961 ccacaacgtc tgggcagtcc aggaaaatga cgacagacgt tgcttcatca agactgcaga
     4021 ggttagacaa ctccactgtt cgcacatact catgttgaca agtcactcaa aggaggcagc
     4081 actgacctgc tatgtcatct tttcagtcta cacgacctaa agtgcactac cacctaggaa
     4141 gacaaatgga gaagcctttg tgaagactga atcctaaggg aataatataa gtaacggttt
     4201 accaaacatt aaatatgtga ctctgggggg agttgggtat tgagtctgat tagtttacta
     4261 tgattgtaat aaaaatgctt aagttatctg atataagagc atcatctacg tcataacttc
     4321 cgtacgtctg atgcctttat gagatggaac cacttgtttt tcttcatgtt gtaatataat
     4381 aggcatttat gtattgctgt gtaccatttc tttttaaatg tgtaagtctt ctgtaaatgg
     4441 atataaatat gattttttaa aaaaataaaa tatatggttc atggagtctc gagtgcaaac
     4501 tgaacaattc caagtactgt ttgtatttta ccatttcacc atttatacgg ttttttgaat
     4561 tgtaatggtc aatcaatatg ttccttagaa gtgtgtttca tgcttcgaca tgcttctcct
     4621 tcaagtctgt caaaccttaa agctgaacac ctgcctctga tcatgtgatt aaacctggag
     4681 cccaaaatga cctttaaagg ccatcaggga tgtgacaccc tctctctctc cttacagaag
     4741 cactgtgatg gctcaacctg tttcaaaaga aaacaaagcc aaactgttta caagagtcaa
     4801 atgcaatgat tttaacaatt tatattatga aaaccattac ctaattttgt tgcctgtgga
     4861 ccaagaaaca cacacacaca caaacacaca tgcatataca cacactttac taaaaactac
     4921 atgttcattc aaatagccaa cactggacag tgaatgtcaa ccattgtaga gtctgagttc
     4981 catttccact ggggtgtggg gtggaggggc agaaccccat aacctacccc cattttaaaa
     5041 atcactgtta acagggcatt agccagactc aagtctgtta ttacgagcct ttagctgaaa
     5101 taaccatttt tttgtgactt ccctgaattc actttcatca gaggaaataa agacagaatg
     5161 attaacatat atagtgtata aaaagtaaag atgagtaatc tcttccttgt ggctttattc
     5221 ggtggtgtca ctgctgttta ttctttattg atatgggaga tttcaaagtg gaacctattt
     5281 aataatacca ttgatctgtt tccctgctgc ttggtcttaa tgcaagaccc gtcattagta
     5341 aattattatt aattttttgt atttcaattc gttgtatttg cacgtacatt tgtttcgatg
     5401 tctatttttg ttgaacagat tcaatcaaac ggtaatggta acagaaaacc tctccattat
     5461 caataaaaca acaacaacaa caacaaatgc ctccagtttc ctgcttaagc tttgttttct
     5521 agtagcctga catttaacga tttatttcga ttaccaagaa aatcattcaa cgatttcaaa
     5581 tgcgattcta ttcaaaattg agtctgccac tagagggagg tctaaaccag ctgatagagg
     5641 tggcttggct tttttttttt tttttttttt aatgttgctt gagtaaagac aatgtgaaag
     5701 aacattgaaa ctctcgattc atcaaaatga aatagataag agaaactctg atacctgcat
     5761 ggcagaaaga tttatactcg tatttagata cctgtgtgac aaacagttgt gcatagctgt
     5821 agtgcaaccc ttgtgataat taacttacaa ggaagaacat tttattttgt cccagcgcat
     5881 ttgatgttcc gtctcaagaa ccggcagtct gcaggctttg gggtcgagtg gcgtggtcgg
     5941 aagcctgtac cagaggaaac tgttcacttc cttgacagga gacatggagc ccggtgctgc
     6001 tgctgctcag ctcgggacac ataagagggc acatttctgt gacctgaaca cttagcatca
     6061 gcattatcct ggccacgcat tcagcacaga agcttttggg ggaataatca atatccaatt
     6121 aggtaaacca ctcacactgt cacctaaagc agtctcgtct ttttagaaat cacctacaaa
     6181 atactgatca tctgtcatag accccgatag tgtgatacaa agtatcaaat tactttcctt
     6241 gagaattatg taaaatattg cttaatgtat aagaaaattg tagtcagcta tatttctggg
     6301 tgttttggtt ttggttttcc cctttagcca tcaatgttag gaattcaaac atgttagaat
     6361 atcagatcgg accctttcaa acacaacttt atataagtaa aacaaccttt tggcgaataa
     6421 aacaagtttc acttttaaaa aaaaaaaaaa aaaa
//
