LOCUS       NM_029315               1395 bp    mRNA    linear   ROD 27-JUL-2024
DEFINITION  Mus musculus POU domain class 5, transcription factor 2 (Pou5f2),
            mRNA.
ACCESSION   NM_029315 XM_889570
VERSION     NM_029315.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1395)
  AUTHORS   Shibata,M., Pattabiraman,K., Lorente-Galdos,B., Andrijevic,D.,
            Kim,S.K., Kaur,N., Muchnik,S.K., Xing,X., Santpere,G., Sousa,A.M.M.
            and Sestan,N.
  TITLE     Regulation of prefrontal patterning and connectivity by retinoic
            acid
  JOURNAL   Nature 598 (7881), 483-488 (2021)
   PUBMED   34599305
REFERENCE   2  (bases 1 to 1395)
  AUTHORS   Frankenberg,S.R., Frank,D., Harland,R., Johnson,A.D., Nichols,J.,
            Niwa,H., Scholer,H.R., Tanaka,E., Wylie,C. and Brickman,J.M.
  TITLE     The POU-er of gene nomenclature
  JOURNAL   Development 141 (15), 2921-2923 (2014)
   PUBMED   25053425
REFERENCE   3  (bases 1 to 1395)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   4  (bases 1 to 1395)
  AUTHORS   Akiyama,K., Noguchi,J., Hirose,M., Kajita,S., Katayama,K.,
            Khalaj,M., Tsuji,T., Fairfield,H., Byers,C., Reinholdt,L., Ogura,A.
            and Kunieda,T.
  TITLE     A mutation in the nuclear pore complex gene Tmem48 causes
            gametogenesis defects in skeletal fusions with sterility (sks) mice
  JOURNAL   J Biol Chem 288 (44), 31830-31841 (2013)
   PUBMED   24045954
REFERENCE   5  (bases 1 to 1395)
  AUTHORS   Hufnagel,R.B., Le,T.T., Riesenberg,A.L. and Brown,N.L.
  TITLE     Neurog2 controls the leading edge of neurogenesis in the mammalian
            retina
  JOURNAL   Dev Biol 340 (2), 490-503 (2010)
   PUBMED   20144606
REFERENCE   6  (bases 1 to 1395)
  AUTHORS   Bassett,E.A., Pontoriero,G.F., Feng,W., Marquardt,T., Fini,M.E.,
            Williams,T. and West-Mays,J.A.
  TITLE     Conditional deletion of activating protein 2alpha (AP-2alpha) in
            the developing retina demonstrates non-cell-autonomous roles for
            AP-2alpha in optic cup development
  JOURNAL   Mol Cell Biol 27 (21), 7497-7510 (2007)
   PUBMED   17724084
REFERENCE   7  (bases 1 to 1395)
  AUTHORS   Pearse,R.V. 2nd, Drolet,D.W., Kalla,K.A., Hooshmand,F.,
            Bermingham,J.R. Jr. and Rosenfeld,M.G.
  TITLE     Reduced fertility in mice deficient for the POU protein sperm-1
  JOURNAL   Proc Natl Acad Sci U S A 94 (14), 7555-7560 (1997)
   PUBMED   9207130
REFERENCE   8  (bases 1 to 1395)
  AUTHORS   Welch,C.L., Xia,Y.R., Shechter,I., Farese,R., Mehrabian,M.,
            Mehdizadeh,S., Warden,C.H. and Lusis,A.J.
  TITLE     Genetic regulation of cholesterol homeostasis: chromosomal
            organization of candidate genes
  JOURNAL   J Lipid Res 37 (7), 1406-1421 (1996)
   PUBMED   8827514
  REMARK    Erratum:[J Lipid Res 1996 Oct;37(10):2269]
REFERENCE   9  (bases 1 to 1395)
  AUTHORS   Andersen,B., Pearse,R.V. 2nd, Schlegel,P.N., Cichon,Z.,
            Schonemann,M.D., Bardin,C.W. and Rosenfeld,M.G.
  TITLE     Sperm 1: a POU-domain gene transiently expressed immediately before
            meiosis I in the male germ cell
  JOURNAL   Proc Natl Acad Sci U S A 90 (23), 11084-11088 (1993)
   PUBMED   7902581
REFERENCE   10 (bases 1 to 1395)
  AUTHORS   Xia,Y.R., Andersen,B., Mehrabian,M., Diep,A.T., Warden,C.H.,
            Mohandas,T., McEvilly,R.J., Rosenfeld,M.G. and Lusis,A.J.
  TITLE     Chromosomal organization of mammalian POU domain factors
  JOURNAL   Genomics 18 (1), 126-130 (1993)
   PUBMED   8276396
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK005948.1 and AK076753.1.
            
            On Jul 26, 2009 this sequence version replaced XM_889570.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK076753.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10                AK005948.1         2-11
            11-1395             AK076753.1         2-1386
FEATURES             Location/Qualifiers
     source          1..1395
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 41.38 cM"
     gene            1..1395
                     /gene="Pou5f2"
                     /gene_synonym="1700013G10Rik; SPRM-1; Sprm1"
                     /note="POU domain class 5, transcription factor 2"
                     /db_xref="GeneID:75507"
                     /db_xref="MGI:MGI:1922757"
     exon            1..1395
                     /gene="Pou5f2"
                     /gene_synonym="1700013G10Rik; SPRM-1; Sprm1"
                     /inference="alignment:Splign:2.1.0"
     CDS             40..1029
                     /gene="Pou5f2"
                     /gene_synonym="1700013G10Rik; SPRM-1; Sprm1"
                     /note="sperm 1 POU domain transcription factor;
                     sperm-associated POU domain protein 1"
                     /codon_start=1
                     /product="POU domain, class 5, transcription factor 2"
                     /protein_id="NP_083591.1"
                     /db_xref="CCDS:CCDS56895.1"
                     /db_xref="GeneID:75507"
                     /db_xref="MGI:MGI:1922757"
                     /translation="MAGRRSSNVFPLSGNSGGGLEVDTPTWLSSQAATSRLMVRPSMG
                     PGICPGPEVWGVPLGSSPYEFRGGIAPYRACEARAWSQSSSEDTCPGPYIALRYMPNL
                     ALPEDVSAIQKEMEQLAKELRQKRMTLGYSQADVGFAVGAMFGKVLSQTTICRFEAQQ
                     LSLANMWKLRPLLKMWLEEVDEKNLLGICRMEMILEQARKRRRASRERRIGSNLEKLF
                     LQCPEPTPQQISYIAGRLRLQKDLVQVWFSNRSQMGSWPTNDTSRREDVGATGSPFPG
                     PPVCFPMAPGLHFDFPHYEGSCLTPLYSSTPFPVRGALLSAPTTTLGLPRLSS"
     regulatory      1263..1268
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pou5f2"
                     /gene_synonym="1700013G10Rik; SPRM-1; Sprm1"
                     /note="hexamer: ATTAAA"
     polyA_site      1300
                     /gene="Pou5f2"
                     /gene_synonym="1700013G10Rik; SPRM-1; Sprm1"
                     /note="major polyA site"
ORIGIN      
        1 agttcctacc agactcctgc tgggggtccc atccacccca tggccgggcg gaggtcttca
       61 aacgtcttcc ctctctcagg caatagtggt ggtggcctgg aagttgacac cccaacatgg
      121 ttgagcagcc aggcagccac aagcagatta atggtgcgac caagtatggg tccaggcatc
      181 tgtccaggcc ctgaggtatg gggagtgcct ctgggctcct caccttatga attccgaggt
      241 gggatagcac cctacagagc ttgtgaggca agggcctggt cccagagttc ctctgaggat
      301 acctgcccag gaccttacat cgccttgaga tacatgccaa atttggcact gccagaggac
      361 gtttcagcca tacagaaaga gatggagcag ctagccaagg aactgagaca aaagaggatg
      421 accctggggt actcacaggc cgatgtggga ttcgctgtgg gagctatgtt tgggaaggtt
      481 ctcagccaga cgaccatatg ccgcttcgag gcccagcagc tcagccttgc caacatgtgg
      541 aagctgcgac ccctgctgaa aatgtggtta gaggaagtag atgagaagaa ccttctgggc
      601 atatgcagaa tggagatgat cctggagcag gcccggaagc ggagacgtgc aagcagagag
      661 agacgcattg ggagcaatct ggaaaaactg ttcttgcaat gtccagagcc tacgccccag
      721 caaatcagct atattgctgg gcgcctccgg ctgcagaaag acctggtcca agtgtggttt
      781 tctaaccgga gccagatggg cagttggcca accaatgata cctcccggag ggaggatgtg
      841 ggggcaactg ggtctccttt cccaggtcca ccagtgtgct ttcccatggc accagggctc
      901 cattttgatt tcccccacta tgagggatca tgccttacac ccctgtactc ctctacccca
      961 tttcctgtac gaggagccct tttgtctgcc ccaaccacca ctctgggcct ccccaggctg
     1021 tcaagctgag gggcctaccc tgcaggggaa taagaggcta gagagaagag ggttttgttt
     1081 cagggttagc gttcagttct ctgacttagt gggtatgggt gggagttgtt tacagaaggc
     1141 ttgggaggga agttaaagag tatcacttgc ttctttttgt tcttaccttg gtttttttcc
     1201 ccccggtgtt ggcattgcaa tatctttatg gctataatgt tttgtttctc tttttattgt
     1261 taattaaaga tgtccattgt tccttgttgt tatcaggaaa cacagtttct ttataaacac
     1321 agtataaaat tagaagcaca agtcacataa aactactgta ctagtgttta ttaaaaacaa
     1381 gcagaaccct gtctc
//
