LOCUS       NM_008901               4730 bp    mRNA    linear   ROD 24-DEC-2024
DEFINITION  Mus musculus POU domain, class 3, transcription factor 4 (Pou3f4),
            mRNA.
ACCESSION   NM_008901
VERSION     NM_008901.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4730)
  AUTHORS   Lekkos,K., Bhuiyan,A.A., Albloshi,A.M.K., Brooks,P.M., Coate,T.M.
            and Lionikas,A.
  TITLE     Validation of positional candidates Rps6ka6 and Pou3f4 for a locus
            associated with skeletal muscle mass variability
  JOURNAL   G3 (Bethesda) 14 (5) (2024)
   PUBMED   38577978
  REMARK    GeneRIF: Validation of positional candidates Rps6ka6 and Pou3f4 for
            a locus associated with skeletal muscle mass variability.
REFERENCE   2  (bases 1 to 4730)
  AUTHORS   Rose,K.P., Manilla,G., Milon,B., Zalzman,O., Song,Y., Coate,T.M.
            and Hertzano,R.
  TITLE     Spatially distinct otic mesenchyme cells show molecular and
            functional heterogeneity patterns before hearing onset
  JOURNAL   iScience 26 (10), 107769 (2023)
   PUBMED   37720106
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4730)
  AUTHORS   Bohuslavova,R., Fabriciova,V., Lebron-Mora,L., Malfatti,J.,
            Smolik,O., Valihrach,L., Benesova,S., Zucha,D., Berkova,Z.,
            Saudek,F., Evans,S.M. and Pavlinkova,G.
  TITLE     ISL1 controls pancreatic alpha cell fate and beta cell maturation
  JOURNAL   Cell Biosci 13 (1), 53 (2023)
   PUBMED   36899442
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4730)
  AUTHORS   Fu,X., Shah,A.P., Keighron,J., Mou,T.M., Ladenheim,B., Alt,J.,
            Fukudome,D., Niwa,M., Tamashiro,K.L., Tanda,G., Sawa,A.,
            Cadet,J.L., Rais,R. and Baraban,J.M.
  TITLE     Elevated body fat increases amphetamine accumulation in brain:
            evidence from genetic and diet-induced forms of adiposity
  JOURNAL   Transl Psychiatry 11 (1), 427 (2021)
   PUBMED   34392304
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4730)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4730)
  AUTHORS   Rowe,L.B., Nadeau,J.H., Turner,R., Frankel,W.N., Letts,V.A.,
            Eppig,J.T., Ko,M.S., Thurston,S.J. and Birkenmeier,E.H.
  TITLE     Maps from two interspecific backcross DNA panels available as a
            community genetic mapping resource
  JOURNAL   Mamm Genome 5 (5), 253-274 (1994)
   PUBMED   8075499
  REMARK    Erratum:[Mamm Genome 1994 Jul;5(7):463]
REFERENCE   7  (bases 1 to 4730)
  AUTHORS   Douville,P.J., Atanasoski,S., Tobler,A., Fontana,A. and Schwab,M.E.
  TITLE     The brain-specific POU-box gene Brn4 is a sex-linked transcription
            factor located on the human and mouse X chromosomes
  JOURNAL   Mamm Genome 5 (3), 180-182 (1994)
   PUBMED   7911044
REFERENCE   8  (bases 1 to 4730)
  AUTHORS   Avraham,K.B., Cho,B.C., Gilbert,D., Fujii,H., Okamoto,K.,
            Shimazaki,T., Ito,T., Shoji,H., Wakamatsu,Y., Kondoh,H. et al.
  TITLE     Murine chromosomal location of four class III POU transcription
            factors
  JOURNAL   Genomics 18 (1), 131-133 (1993)
   PUBMED   8276397
REFERENCE   9  (bases 1 to 4730)
  AUTHORS   Xia,Y.R., Andersen,B., Mehrabian,M., Diep,A.T., Warden,C.H.,
            Mohandas,T., McEvilly,R.J., Rosenfeld,M.G. and Lusis,A.J.
  TITLE     Chromosomal organization of mammalian POU domain factors
  JOURNAL   Genomics 18 (1), 126-130 (1993)
   PUBMED   8276396
REFERENCE   10 (bases 1 to 4730)
  AUTHORS   Hara,Y., Rovescalli,A.C., Kim,Y. and Nirenberg,M.
  TITLE     Structure and evolution of four POU domain genes expressed in mouse
            brain
  JOURNAL   Proc Natl Acad Sci U S A 89 (8), 3280-3284 (1992)
   PUBMED   1565620
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY309115.1, BC145919.1, BC086670.1 and AL672221.14.
            
            On Aug 25, 2015 this sequence version replaced NM_008901.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: X66603.1, SRR7652917.1023755.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-11                BY309115.1         2-12
            12-1193             BC145919.1         1-1182
            1194-1508           BC086670.1         1171-1485
            1509-4730           AL672221.14        91516-94737
FEATURES             Location/Qualifiers
     source          1..4730
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 48.2 cM"
     gene            1..4730
                     /gene="Pou3f4"
                     /gene_synonym="Brn-4; Brn4; oct-9; OTF-9; Otf9; Slf"
                     /note="POU domain, class 3, transcription factor 4"
                     /db_xref="GeneID:18994"
                     /db_xref="MGI:MGI:101894"
     exon            1..4730
                     /gene="Pou3f4"
                     /gene_synonym="Brn-4; Brn4; oct-9; OTF-9; Otf9; Slf"
                     /inference="alignment:Splign:2.1.0"
     CDS             87..1172
                     /gene="Pou3f4"
                     /gene_synonym="Brn-4; Brn4; oct-9; OTF-9; Otf9; Slf"
                     /note="brain-4 class III POU-domain protein;
                     octamer-binding protein 9; octamer-binding transcription
                     factor 9; brain-specific homeobox/POU domain protein 4;
                     sex linked fidget"
                     /codon_start=1
                     /product="POU domain, class 3, transcription factor 4"
                     /protein_id="NP_032927.1"
                     /db_xref="CCDS:CCDS30355.1"
                     /db_xref="GeneID:18994"
                     /db_xref="MGI:MGI:101894"
                     /translation="MATAASNPYSILSSSSLVHADSAGMQQGSPFRNPQKLLQSDYLQ
                     GVPSNGHPLGHHWVTSLSDGGPWSSTLATSPLDQQDVKPGREDLQLGAIIHHRSPHVA
                     HHSPHTNHPNAWGASPAPNSSITSSGQPLNVYSQPGFTVSGMLEHGGLTPPPAAASTQ
                     SLHPVLREPPDHGELGSHHCQDHSDEETPTSDELEQFAKQFKQRRIKLGFTQADVGLA
                     LGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQG
                     RKRKKRTSIEVSVKGVLETHFLKCPKPAAQEISSLADSLQLEKEVVRVWFCNRRQKEK
                     RMTPPGDQQPHEVYSHTVKTDASCHDL"
     regulatory      3485..3490
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pou3f4"
                     /gene_synonym="Brn-4; Brn4; oct-9; OTF-9; Otf9; Slf"
                     /note="hexamer: AATAAA"
     polyA_site      3507
                     /gene="Pou3f4"
                     /gene_synonym="Brn-4; Brn4; oct-9; OTF-9; Otf9; Slf"
                     /note="major polyA site"
     regulatory      3570..3575
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pou3f4"
                     /gene_synonym="Brn-4; Brn4; oct-9; OTF-9; Otf9; Slf"
                     /note="hexamer: AATAAA"
     polyA_site      3588
                     /gene="Pou3f4"
                     /gene_synonym="Brn-4; Brn4; oct-9; OTF-9; Otf9; Slf"
ORIGIN      
        1 ggctttggtt cccccgcacc atagatgtca aaggctgaag ctgctccctt tgccacatta
       61 taactagtag aggatcctca tcgaccatgg ccacagctgc ctcgaatccc tacagcattc
      121 tcagttccag ctcccttgtc catgcggact ccgcgggcat gcagcaggga agtcctttcc
      181 gcaatcctca gaaacttctc caaagtgact acttgcaggg agttcccagc aatgggcatc
      241 ccctcgggca tcactgggtg accagtctta gcgacggggg cccgtggtcc tccacattgg
      301 ccaccagccc cctggaccag caagacgtga agccgggacg cgaagatctg caactgggcg
      361 caatcatcca tcaccgctcg ccgcacgtag cccaccactc gccgcacact aaccatccga
      421 acgcctgggg agcgagccct gctccaaact cgtccatcac gtccagcggc caacccctca
      481 atgtgtactc gcagccaggc ttcaccgtga gcggtatgct ggagcacggg ggactcactc
      541 caccaccagc tgctgcctcc acacagagcc tgcatccagt gctccgggag cctccagacc
      601 atggtgagct gggctcgcac cactgccagg accactctga tgaagagact ccaacctctg
      661 atgagttgga acagttcgcc aaacaattca aacaaagaag aatcaagttg ggcttcacgc
      721 aagccgacgt ggggctggca ctgggcacac tgtatggcaa cgtgttctcg cagactacca
      781 tctgcaggtt cgaggcctta caactgagct tcaagaacat gtgcaagctg aaaccgctat
      841 taaataagtg gctggaggag gctgattcat ccacaggaag cccgaccagc attgacaaga
      901 tcgctgctca aggccgcaaa cgcaagaagc gaacctccat cgaggtgagt gtcaagggcg
      961 tactggaaac acatttcctc aagtgtccca agcctgcagc gcaggagatc tcctcgctgg
     1021 cagacagtct ccagttggag aaagaagtgg tgcgtgtctg gttctgtaat agaagacaaa
     1081 aagaaaaaag aatgactccg ccaggggatc agcagccaca cgaggtttat tcgcacacgg
     1141 tgaaaacaga cgcgtcctgc cacgatctct gactggagga agcaaggagg tggcccgctg
     1201 cactgggagc agtgctgata caattctctc tttaccttcc tttcagcatt acatccttta
     1261 ttgttgctat ctctctagct tgctagctct tcttttcttt cacaggggtt tctaacttct
     1321 tatgacttat gttaagaaaa gaaacacaca cacgcgcgcg cgctcaggca aacacgcacg
     1381 cacgcgcgcg cgcgcgcgcg cgcacacaca cacacacaca cacacacaca cacacacaca
     1441 tacacacaca cattcaggct tctcaactct gaaacacaat tatattaaga agtccaggtg
     1501 gggaccctgt attccctgct gccaggacaa tttccctcca acctttttct gctgatcaat
     1561 atatattgtt tactctgagt aagatttgtt tggttgctcc tctctaagaa gggcaaggag
     1621 ctgggtaacg ggtggggggc gggggagggt gggaagacag atgtgtgcct atgaataacc
     1681 tttcagcgcc ttggttatag cagctgtatt tcaggtgaaa tctgttttac aatagactag
     1741 ttttgcattt ttttaaaact tctatagcgt ttctaattgt ctgcggtgtt ttactacaag
     1801 ctgtacacaa tatttgtgag ataatttgta tctaatcgac cactccacat tattattgct
     1861 attattatta tttcttcatt gagctgatgg gtttttaatt gcttaaaaag ggagggaggc
     1921 tgaaaggagg agagagaaaa atgctcacct cctgcactcc cacacttgag gagaggatat
     1981 ggtggagaaa gttgttgatg cttctatttt cccccccgga actgagtgcc tatatgggca
     2041 gaacaagcaa actgaatagg tttgcaaagt agcctgaagg ctatttcgct gcttttttgc
     2101 cccctccccc gactttcacg gaactgtgga gccctggaag gcttccacag cacagatccc
     2161 ggtgccccag aaggattcag ctgtggcgcg aagaatggga tgtgagcgac ctgaaggatt
     2221 ctgaattcac caaggtcgtg aatgcctgtg cgtgaagttt cccacaggcc gccagcttag
     2281 tcgggttgac aacctgcgct accctatgta cactctccta gatgaaagac ttggccttca
     2341 caaatggtgg ctttcaaagg agaccactac ccaaagactc tggcgcccta ttgggccagc
     2401 gcctcccagt tcagttcacc tccagttcgc cgctcgctct cagggtgaga aacgctctcg
     2461 gtagggtggt gagggggtag gcatcttcag cttcgtgcgg agagacaata aaataattgg
     2521 caaaagtcac gaagattctg gtccagccgc acaccacctc ctccctcttg tacataccaa
     2581 ggtctgagta agctcttagg gagcccttct cagtgtcttt gacaagcaca gctggtggaa
     2641 gcccaaggcg cagatcgagc gagctagcga gcgcctgggc ggctaagttt atgctttttt
     2701 ttttctttta aaaatctgtg tgtatgtatt tctgtgagtg tgtggtgtgc gcgtgcaaac
     2761 gtatgtgtgt agatagctgt gtgtaccgta ttactgtata caaaaaagaa aaaaaaatga
     2821 aaaaaaaaat ctccttagac tatgtagaga tcccaaaacg aagcggttgc cgtggcttta
     2881 tggctagctt tctctcatgt ccacaggaca ggttcacagg tgcacctcat ccccagcaag
     2941 cactgtgtgc tggcccagtg aagcgtccat gcccagccag ccacagcgtg cctgacctga
     3001 aggggatctc gccaggaggc tgatctcagg attcagcttg ccggtgcgca gctgtggtag
     3061 acaaagcttc aaactaccta aggaccagaa aaccttgtgc cccttgtgta agatgcgcta
     3121 gtatgggctg ccaggttgac cacattgtgt ctcccctagc cgcaggtcaa agagcttata
     3181 ttaattcaaa ttccagaccc tttcttttgc tatttttttt ttcttggtca agcctctaca
     3241 ttcttagttt taggctttag ttctgtgatt ttattttcct gttcaattca tgtttcacaa
     3301 atgttcgaag gtgggtgggt tatttgtttt tgttttttct ttgcagttaa atgctatggt
     3361 tcaaacctga gttaacccaa atatttctgc cgactttata attgtacagt tttgtatatt
     3421 aaacgttttt gaagttatta atttaaaaag atcatttagt ttattcattt agtaactgat
     3481 gtataataaa cgctattttc attaagagtt gctttttcaa ctattttatt caaattgcct
     3541 attgcagttc ccaacgatta tttattttca ataaattctg cattgtgttt aaatggaaat
     3601 tgtttcaaag atgagttggg tgtcaaaaag aaaacaattc gctgtaacgt ttgatgtgag
     3661 cagttttagt caaggggttt atattgacgc aatattttat tgttgtaaaa gatttaaaag
     3721 gtttaaataa aacatttttc caaaaaaaaa tcatgttttc ttctcctggc cttcatgtgc
     3781 tgtgtgtgaa gtggagcatt taaagaagca catcttgggt gagcaaggca tttgctttgc
     3841 ttcgggtaag aaaccgttag tttttgtatt gattctggtt actattcctc tgatgtttgc
     3901 cttttggttc agaagtatac tctcacacat aatacctatt tgtgcactca tatccatgtg
     3961 ctagagcaaa atgtactctt caagggtggg gagacttgct gggaagaaca ctggcaagcc
     4021 aggtccaaga ctatttcctt agtgttctcc gagagcataa tgtctttgtc aaccagtgtt
     4081 ttctagtcag acccccatcc tgaaattata cccaaacctt ccctggactt gtacatttct
     4141 tacatacctt tatctgtctt ctttctcccc actcctgaca agcccttcta gtaagggacc
     4201 tggatatgtt tttaatgtaa gtgttagtgt tcatcttaag gtgctccctg ggcccagaaa
     4261 cctcaaacaa atggtgtttt tcaatcccta tttatctggt ttgcaagaag aaaacaaaca
     4321 agtaaaaata acaaggatta tgagagaact gggagaattt tgatttatta tactcatctt
     4381 tccactccca catatgattt taaatgtatt attgatttca taaattcttc cacaaaaata
     4441 agcgactgct acctgtagtg gcagctaaag agtaatatgc caactatgag acaattctac
     4501 tttaaggaca agcatgcttt gttcaaactt tttttcttga ttggtgtttt tgaagaaata
     4561 aacaaaatac aatttctggc aataagtacc cccttcaact catactctga tatagatatt
     4621 tctcttagac aaatcataat tgtttaatca ctttaatagc taatgattat gatgtatgtc
     4681 ttgacgtttt cagattgcac aattatttat agctgtatag taaaacacac
//
