LOCUS       NM_001372554            1326 bp    mRNA    linear   ROD 09-JUN-2024
DEFINITION  Mus musculus POU domain, class 2, associating factor 2 (Pou2af2),
            transcript variant 1, mRNA.
ACCESSION   NM_001372554 XM_006510587
VERSION     NM_001372554.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1326)
  AUTHORS   Wu,X.S., He,X.Y., Ipsaro,J.J., Huang,Y.H., Preall,J.B., Ng,D.,
            Shue,Y.T., Sage,J., Egeblad,M., Joshua-Tor,L. and Vakoc,C.R.
  TITLE     OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell
            lineage
  JOURNAL   Nature 607 (7917), 169-175 (2022)
   PUBMED   35576971
  REMARK    GeneRIF: OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft
            cell lineage.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122499.4 and AC160052.2.
            
            On Sep 4, 2019 this sequence version replaced XM_006510587.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5286961.44885.1,
                                           SRR5286962.12973.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849376
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-111               AC122499.4         111645-111755
            112-221             AC122499.4         122173-122282
            222-264             AC160052.2         3900-3942
            265-563             AC160052.2         7054-7352
            564-1326            AC160052.2         8451-9213
FEATURES             Location/Qualifiers
     source          1..1326
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 28.05 cM"
     gene            1..1326
                     /gene="Pou2af2"
                     /gene_synonym="1810046K07Rik; Oca-t1"
                     /note="POU domain, class 2, associating factor 2"
                     /db_xref="GeneID:69809"
                     /db_xref="MGI:MGI:1917059"
     exon            1..111
                     /gene="Pou2af2"
                     /gene_synonym="1810046K07Rik; Oca-t1"
                     /inference="alignment:Splign:2.1.0"
     CDS             102..965
                     /gene="Pou2af2"
                     /gene_synonym="1810046K07Rik; Oca-t1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     uncharacterized protein C11orf53 homolog; OCA-B homolog;
                     protein POU2AF2; oct coactivator from tuft cells 1; POU
                     class 2 homeobox-associating factor 2"
                     /codon_start=1
                     /product="POU domain class 2-associating factor 2 isoform
                     1"
                     /protein_id="NP_001359483.1"
                     /db_xref="CCDS:CCDS90567.1"
                     /db_xref="GeneID:69809"
                     /db_xref="MGI:MGI:1917059"
                     /translation="MDSVPRDYSKRVYQGVRVKHTVKDLLAEKRSRQTSNTRLNGSVS
                     SSQPPFIQMPGSPVMSGYYGVRRSFLSDSDFHSSKQFSNDLYTSGMSKPFACESTAGQ
                     SHTGLLESYLAEPYGDYRPPALTPTPSSLFSTSTLPPLLPPPFPSDPTHFVFRDSWEQ
                     TVPDGLSQPDPMPADALQSLPPSTSCLSQLESGSSTQHRNMGWGASLAGAQSYSLHAL
                     EDLHHTPGYPTSPPYPFTSFMTVSNDLPPKVGPLSPEEGSDVSSLHDPSPWTKEDGSM
                     AWGSYECRRAY"
     exon            112..221
                     /gene="Pou2af2"
                     /gene_synonym="1810046K07Rik; Oca-t1"
                     /inference="alignment:Splign:2.1.0"
     exon            222..264
                     /gene="Pou2af2"
                     /gene_synonym="1810046K07Rik; Oca-t1"
                     /inference="alignment:Splign:2.1.0"
     exon            265..563
                     /gene="Pou2af2"
                     /gene_synonym="1810046K07Rik; Oca-t1"
                     /inference="alignment:Splign:2.1.0"
     exon            564..1326
                     /gene="Pou2af2"
                     /gene_synonym="1810046K07Rik; Oca-t1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1298..1303
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pou2af2"
                     /gene_synonym="1810046K07Rik; Oca-t1"
                     /note="hexamer: ATTAAA"
     polyA_site      1324
                     /gene="Pou2af2"
                     /gene_synonym="1810046K07Rik; Oca-t1"
                     /note="major polyA site"
ORIGIN      
        1 agaaggcttc cttcacacag gaccaggctg aactaaccaa gagttcagga cccctcccta
       61 aggacatttc tcagaggcct ggcactgtgg caccacccag gatggacagc gtcccaagag
      121 attacagcaa acgcgtgtac cagggtgtga gagtgaagca cacagtcaaa gatctcctgg
      181 cagaaaagcg atccaggcag acaagtaaca ccagactcaa tggcagtgtc agctcctccc
      241 agcctccgtt catccagatg ccaggatcgc cagtgatgtc aggttactat ggtgtcagga
      301 gatccttcct gtccgattcc gacttccata gcagcaaaca gttctcgaat gacctctaca
      361 cctccggcat gagcaagccc tttgcctgcg agtccacggc tgggcagagt cacacaggcc
      421 tgctggaatc ctacctggct gagccctatg gagactaccg cccaccagcg ctgaccccca
      481 cacccagttc cctgttcagc acctcgactc tgccaccgct cttgccgcct ccgttcccca
      541 gtgacccaac tcatttcgtc tttagagact cctgggaaca gacggtacca gatggtctca
      601 gccagccaga ccccatgcct gctgatgccc tgcagagttt gccacccagc accagttgcc
      661 tctcccaact ggagtcagga agcagcaccc agcacaggaa catgggctgg ggggcatccc
      721 ttgctggggc tcagtcctac tcgctgcatg cactggaaga tctgcaccac acaccagggt
      781 accctacctc acctccatac cccttcacgt ctttcatgac agtgtcaaat gacctcccac
      841 ccaaggtggg gcccctctcc ccagaggaag ggtcagatgt ctcttctctt catgatcctt
      901 caccttggac aaaagaagat ggcagtatgg cctggggctc ttatgagtgc cggagagctt
      961 actgagaagc aggccagagg acttctgcat ccttatagag aagttggact ctgtgtccac
     1021 agagttttct aggtgtgctt gctcattcag aactggattt tcagtttaag ccacaattct
     1081 gtcagtgcta gttgacaaca gtactcatcc ctgttcttat ccactgtaaa acccctacaa
     1141 aacactacaa tgtcaatcaa atgttttgtg gatcacatcc taatgagaca accttcacaa
     1201 ggaggccacc ttagagcttt aggaacccat ttcattctaa attttctgtt acctttaaag
     1261 cattattttt tggcactagt tatttttctt atattgcatt aaaaactttg tgcagaacat
     1321 aaaaca
//
