LOCUS       NM_026398               1340 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus processing of precursor 5, ribonuclease P/MRP family
            (S. cerevisiae) (Pop5), transcript variant 1, mRNA.
ACCESSION   NM_026398 XM_993830 XM_993851
VERSION     NM_026398.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1340)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1340)
  AUTHORS   Nakahara,M., Tateyama,H., Araki,M., Nakagata,N., Yamamura,K. and
            Araki,K.
  TITLE     Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from
            MSM/Ms mice
  JOURNAL   Mamm Genome 24 (5-6), 228-239 (2013)
   PUBMED   23604909
REFERENCE   3  (bases 1 to 1340)
  AUTHORS   Taniwaki,T., Haruna,K., Nakamura,H., Sekimoto,T., Oike,Y.,
            Imaizumi,T., Saito,F., Muta,M., Soejima,Y., Utoh,A., Nakagata,N.,
            Araki,M., Yamamura,K. and Araki,K.
  TITLE     Characterization of an exchangeable gene trap using pU-17 carrying
            a stop codon-beta geo cassette
  JOURNAL   Dev Growth Differ 47 (3), 163-172 (2005)
   PUBMED   15840001
REFERENCE   4  (bases 1 to 1340)
  AUTHORS   Xiao,S., Scott,F., Fierke,C.A. and Engelke,D.R.
  TITLE     Eukaryotic ribonuclease P: a plurality of ribonucleoprotein enzymes
  JOURNAL   Annu Rev Biochem 71, 165-189 (2002)
   PUBMED   12045094
  REMARK    Review article
REFERENCE   5  (bases 1 to 1340)
  AUTHORS   van Eenennaam,H., Lugtenberg,D., Vogelzangs,J.H., van Venrooij,W.J.
            and Pruijn,G.J.
  TITLE     hPop5, a protein subunit of the human RNase MRP and RNase P
            endoribonucleases
  JOURNAL   J Biol Chem 276 (34), 31635-31641 (2001)
   PUBMED   11413139
REFERENCE   6  (bases 1 to 1340)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC145070.10.
            
            On Apr 1, 2022 this sequence version replaced NM_026398.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.1943730.1,
                                           SRR17784648.1201861.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-383               AC145070.10        85704-86086         c
            384-629             AC145070.10        83519-83764         c
            630-772             AC145070.10        83311-83453         c
            773-922             AC145070.10        81277-81426         c
            923-1006            AC145070.10        81032-81115         c
            1007-1340           AC145070.10        80616-80949         c
FEATURES             Location/Qualifiers
     source          1..1340
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 56.01 cM"
     gene            1..1340
                     /gene="Pop5"
                     /gene_synonym="1500019J17Rik; 2700077E03Rik; Rnasep3"
                     /note="processing of precursor 5, ribonuclease P/MRP
                     family (S. cerevisiae)"
                     /db_xref="GeneID:117109"
                     /db_xref="MGI:MGI:2151221"
     exon            1..383
                     /gene="Pop5"
                     /gene_synonym="1500019J17Rik; 2700077E03Rik; Rnasep3"
                     /inference="alignment:Splign:2.1.0"
     exon            384..629
                     /gene="Pop5"
                     /gene_synonym="1500019J17Rik; 2700077E03Rik; Rnasep3"
                     /inference="alignment:Splign:2.1.0"
     CDS             610..1119
                     /gene="Pop5"
                     /gene_synonym="1500019J17Rik; 2700077E03Rik; Rnasep3"
                     /EC_number="3.1.26.5"
                     /note="isoform 1 is encoded by transcript variant 1;
                     ribonuclease P/MRP protein subunit POP5"
                     /codon_start=1
                     /product="ribonuclease P/MRP protein subunit POP5 isoform
                     1"
                     /protein_id="NP_080674.1"
                     /db_xref="CCDS:CCDS19583.1"
                     /db_xref="GeneID:117109"
                     /db_xref="MGI:MGI:2151221"
                     /translation="MVRFKHRYLLCELVSEDARCRLSLDDRVLGGLVRDTIARVHGAF
                     GAAACSVGFAVRYLNAYTGVVLLRCRKDFYQLVWSALPFITYLENKGHRYPCFFNTLH
                     VGGTIRTCQKFLIQYNRRQLLILLQNCTDEGEREAIKKSVSRSCLLDREPVEELSDSA
                     GEEVAEAME"
     exon            630..772
                     /gene="Pop5"
                     /gene_synonym="1500019J17Rik; 2700077E03Rik; Rnasep3"
                     /inference="alignment:Splign:2.1.0"
     exon            773..922
                     /gene="Pop5"
                     /gene_synonym="1500019J17Rik; 2700077E03Rik; Rnasep3"
                     /inference="alignment:Splign:2.1.0"
     exon            923..1006
                     /gene="Pop5"
                     /gene_synonym="1500019J17Rik; 2700077E03Rik; Rnasep3"
                     /inference="alignment:Splign:2.1.0"
     exon            1007..1340
                     /gene="Pop5"
                     /gene_synonym="1500019J17Rik; 2700077E03Rik; Rnasep3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1317..1322
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pop5"
                     /gene_synonym="1500019J17Rik; 2700077E03Rik; Rnasep3"
                     /note="hexamer: AATAAA"
     polyA_site      1340
                     /gene="Pop5"
                     /gene_synonym="1500019J17Rik; 2700077E03Rik; Rnasep3"
                     /note="major polyA site"
ORIGIN      
        1 gattgcaaac agccgccggc ctcattagga gacgtgtaat tagcggctgg cggagccgag
       61 ggcgggggct aattaccacc gggagaggct gcgacgacac gtcgccgccg ccggcccacc
      121 gggaggcgtc tggcccgcac ttcccggctg gcccggatca gggtgcttcc tctgggtgac
      181 agccgctcgc cgttgtttgt ttattaggca cccgccctcc cgtgccggtg caatcccacc
      241 tacacctcca tcctaataat tcttaataat cggaactaga aggggaagct ctgctttgga
      301 gacgcggtgt ggtccctgac agcaccgggc cggaggacga agaccgggga tccgaaccca
      361 cgcctgtggc tacgttacag caggtcccag atcgtgcgac actctcggac tttaagtgca
      421 gggctgacct taaacgttca cttgggggac tctgagcgca cagaacttgt gtggaaaatc
      481 cccagcgccg gccggaggcg aacgcatgcg ctcttacgcc cgccgcggga ggcggagcgt
      541 ggagattgac agggcacgct gcctgtccga gcctagtgcc gccttcctcc cgcatccggc
      601 gcggacgcca tggtgcggtt caagcacagg taccttctgt gcgagctggt gtccgaggac
      661 gcgcgctgcc gtttgagcct ggacgaccgc gtgctgggcg ggctggtccg cgacacgatc
      721 gcccgggtgc acggggcctt cggcgccgcc gcctgctccg tgggctttgc agtccgatac
      781 ctcaatgcct acactggagt cgtgctactg cgatgccgga aggatttcta ccagctcgtg
      841 tggtcagctc ttcctttcat cacctatttg gagaacaaag gccaccgtta cccgtgcttc
      901 ttcaacacat tacacgtggg aggtaccatc agaacctgtc agaagttcct gatccagtac
      961 aacaggagac agctgctgat cttgttgcag aattgcactg acgaaggaga gcgggaagcc
     1021 atcaagaagt ctgtctcaag aagctgtctg ctggacagag agcccgttga agagctttca
     1081 gacagtgctg gtgaggaggt tgcagaagca atggagtgac cgtttccagg cccacttgtg
     1141 ggaacaggac attacaggag gtgacagcag catcccacag ttctccaatg gaaatgactg
     1201 ataaccagca ctcaggtgac cagcttgaag tggagggctt gctgccttac cttgcatcca
     1261 tggttgtgaa ggctctgtgc agacatttcg gatgtaactg cttagctcag gggtggaata
     1321 aacattccta aaccataaaa
//
