LOCUS       NM_025624                740 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus proteasome maturation protein (Pomp), mRNA.
ACCESSION   NM_025624
VERSION     NM_025624.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 740)
  AUTHORS   Chu,V.T., Graf,R., Wirtz,T., Weber,T., Favret,J., Li,X., Petsch,K.,
            Tran,N.T., Sieweke,M.H., Berek,C., Kuhn,R. and Rajewsky,K.
  TITLE     Efficient CRISPR-mediated mutagenesis in primary immune cells using
            CrispRGold and a C57BL/6 Cas9 transgenic mouse line
  JOURNAL   Proc Natl Acad Sci U S A 113 (44), 12514-12519 (2016)
   PUBMED   27729526
REFERENCE   2  (bases 1 to 740)
  AUTHORS   Shin,S.W., Shimizu,N., Tokoro,M., Nishikawa,S., Hatanaka,Y.,
            Anzai,M., Hamazaki,J., Kishigami,S., Saeki,K., Hosoi,Y.,
            Iritani,A., Murata,S. and Matsumoto,K.
  TITLE     Mouse zygote-specific proteasome assembly chaperone important for
            maternal-to-zygotic transition
  JOURNAL   Biol Open 2 (2), 170-182 (2013)
   PUBMED   23429752
REFERENCE   3  (bases 1 to 740)
  AUTHORS   Burri,L., Hockendorff,J., Boehm,U., Klamp,T., Dohmen,R.J. and
            Levy,F.
  TITLE     Identification and characterization of a mammalian protein
            interacting with 20S proteasome precursors
  JOURNAL   Proc Natl Acad Sci U S A 97 (19), 10348-10353 (2000)
   PUBMED   10973495
REFERENCE   4  (bases 1 to 740)
  AUTHORS   Griffin,T.A., Slack,J.P., McCluskey,T.S., Monaco,J.J. and
            Colbert,R.A.
  TITLE     Identification of proteassemblin, a mammalian homologue of the
            yeast protein, Ump1p, that is required for normal proteasome
            assembly
  JOURNAL   Mol Cell Biol Res Commun 3 (4), 212-217 (2000)
   PUBMED   10891394
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK011115.1 and AK012455.1.
            
            [WARNING] On Mar 12, 2025 this sequence was replaced by
            NM_025624.4.
            
            On May 17, 2018 this sequence version replaced NM_025624.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK012455.1, DV063920.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-734               AK011115.1         2-735
            735-740             AK012455.1         697-702
FEATURES             Location/Qualifiers
     source          1..740
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 87.52 cM"
     gene            1..740
                     /gene="Pomp"
                     /gene_synonym="2510048O06Rik; Ump1"
                     /note="proteasome maturation protein"
                     /db_xref="GeneID:66537"
                     /db_xref="MGI:MGI:1913787"
     exon            1..64
                     /gene="Pomp"
                     /gene_synonym="2510048O06Rik; Ump1"
                     /inference="alignment:Splign:2.1.0"
     CDS             62..487
                     /gene="Pomp"
                     /gene_synonym="2510048O06Rik; Ump1"
                     /note="proteassemblin; protein UMP1 homolog"
                     /codon_start=1
                     /product="proteasome maturation protein"
                     /protein_id="NP_079900.1"
                     /db_xref="CCDS:CCDS39402.1"
                     /db_xref="GeneID:66537"
                     /db_xref="MGI:MGI:1913787"
                     /translation="MNARGLGSELKDSIPVAELSASGPFESHDLLRKGFSCVKNELLP
                     SHPLELSEKNFQLNQDKMNFSTLRNIQGLFAPLKLQMEFKAVQQVHRLPFLPSSNLSL
                     DILRGNDETIGFEDILNDPSQSELMGEPHVMVEHKLGLL"
     exon            65..162
                     /gene="Pomp"
                     /gene_synonym="2510048O06Rik; Ump1"
                     /inference="alignment:Splign:2.1.0"
     exon            163..223
                     /gene="Pomp"
                     /gene_synonym="2510048O06Rik; Ump1"
                     /inference="alignment:Splign:2.1.0"
     exon            224..325
                     /gene="Pomp"
                     /gene_synonym="2510048O06Rik; Ump1"
                     /inference="alignment:Splign:2.1.0"
     exon            326..419
                     /gene="Pomp"
                     /gene_synonym="2510048O06Rik; Ump1"
                     /inference="alignment:Splign:2.1.0"
     exon            420..740
                     /gene="Pomp"
                     /gene_synonym="2510048O06Rik; Ump1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      710..715
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pomp"
                     /gene_synonym="2510048O06Rik; Ump1"
                     /note="hexamer: AATAAA"
     polyA_site      738
                     /gene="Pomp"
                     /gene_synonym="2510048O06Rik; Ump1"
                     /note="major polyA site"
ORIGIN      
        1 agtgagcggt ttggccggcg gactcgagca ggtttataga tctcacagag ctgtttcaaa
       61 gatgaacgcc agaggtcttg ggtcggagct gaaggacagt attccagtcg cggagctctc
      121 agccagcggg cctttcgaga gtcacgatct tctccggaaa gggttttctt gtgtgaaaaa
      181 tgaacttttg cccagtcacc ctctcgagtt atcagaaaaa aacttccagc tcaaccagga
      241 caagatgaac ttttccacgc tgaggaacat ccagggtctg tttgctcccc tgaagttaca
      301 gatggaattc aaggcagtgc agcaggttca ccgtctcccg tttctcccga gctcaaacct
      361 ctcactggat attttgaggg gcaacgatga gaccattggt tttgaggata ttcttaatga
      421 tccatcacaa agtgaactga tgggtgagcc ccacgtgatg gtggaacata agctgggctt
      481 gctgtaataa ggggcccgcg cagggaggaa cgacgagtgt gctcagcata gttgcctgct
      541 acagtctgat gttcacagca gtaaagtaca gagaggatca ctgggccatg tggaagcatt
      601 tgaggcttgg ttttgggttg tgggtcagtt gagagcctag aggtggttct gaggttatag
      661 caaagctcaa attctgaaaa tgtgtgtctt ataaatgtta taaaaacgca ataaagtccc
      721 cgggagttac cttgagaatc
//
