LOCUS       NM_025901               2925 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus polymerase (RNA) III (DNA directed) polypeptide K
            (Polr3k), mRNA.
ACCESSION   NM_025901
VERSION     NM_025901.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2925)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   2  (bases 1 to 2925)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   3  (bases 1 to 2925)
  AUTHORS   Sansom,S.N., Griffiths,D.S., Faedo,A., Kleinjan,D.J., Ruan,Y.,
            Smith,J., van Heyningen,V., Rubenstein,J.L. and Livesey,F.J.
  TITLE     The level of the transcription factor Pax6 is essential for
            controlling the balance between neural stem cell self-renewal and
            neurogenesis
  JOURNAL   PLoS Genet 5 (6), e1000511 (2009)
   PUBMED   19521500
REFERENCE   4  (bases 1 to 2925)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY003788.1, AK031110.1 and AK161764.1.
            
            On Mar 24, 2007 this sequence version replaced NM_025901.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660813.6441.1, BC025898.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-66                BY003788.1         1-66
            67-2050             AK031110.1         2-1985
            2051-2925           AK161764.1         1694-2568
FEATURES             Location/Qualifiers
     source          1..2925
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 103.82 cM"
     gene            1..2925
                     /gene="Polr3k"
                     /gene_synonym="12.3kDa; 1500004O14Rik; C11; RPC10; RPC11"
                     /note="polymerase (RNA) III (DNA directed) polypeptide K"
                     /db_xref="GeneID:67005"
                     /db_xref="MGI:MGI:1914255"
     exon            1..210
                     /gene="Polr3k"
                     /gene_synonym="12.3kDa; 1500004O14Rik; C11; RPC10; RPC11"
                     /inference="alignment:Splign:2.1.0"
     CDS             100..426
                     /gene="Polr3k"
                     /gene_synonym="12.3kDa; 1500004O14Rik; C11; RPC10; RPC11"
                     /EC_number="2.7.7.6"
                     /note="RNA polymerase III subunit C10; RNA polymerase III
                     subunit C11; DNA-directed RNA polymerase III subunit K"
                     /codon_start=1
                     /product="DNA-directed RNA polymerase III subunit RPC10"
                     /protein_id="NP_080177.1"
                     /db_xref="CCDS:CCDS17225.1"
                     /db_xref="GeneID:67005"
                     /db_xref="MGI:MGI:1914255"
                     /translation="MLLFCPGCGNGLIVEEGQRCHRFACNTCPYVHNITRKVTNRKYP
                     KLKEVDDVLGGAAAWENVDSTAEPCPKCEHPRAYFMQLQTRSADEPMTTFYKCCNAQC
                     GHRWRD"
     exon            211..298
                     /gene="Polr3k"
                     /gene_synonym="12.3kDa; 1500004O14Rik; C11; RPC10; RPC11"
                     /inference="alignment:Splign:2.1.0"
     exon            299..2925
                     /gene="Polr3k"
                     /gene_synonym="12.3kDa; 1500004O14Rik; C11; RPC10; RPC11"
                     /inference="alignment:Splign:2.1.0"
     regulatory      673..678
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Polr3k"
                     /gene_synonym="12.3kDa; 1500004O14Rik; C11; RPC10; RPC11"
                     /note="hexamer: AATAAA"
     polyA_site      705
                     /gene="Polr3k"
                     /gene_synonym="12.3kDa; 1500004O14Rik; C11; RPC10; RPC11"
                     /note="major polyA site"
     regulatory      1724..1729
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Polr3k"
                     /gene_synonym="12.3kDa; 1500004O14Rik; C11; RPC10; RPC11"
                     /note="hexamer: ATTAAA"
     polyA_site      1746
                     /gene="Polr3k"
                     /gene_synonym="12.3kDa; 1500004O14Rik; C11; RPC10; RPC11"
     regulatory      2240..2245
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Polr3k"
                     /gene_synonym="12.3kDa; 1500004O14Rik; C11; RPC10; RPC11"
                     /note="hexamer: TATAAA"
     polyA_site      2260
                     /gene="Polr3k"
                     /gene_synonym="12.3kDa; 1500004O14Rik; C11; RPC10; RPC11"
ORIGIN      
        1 gatcccgggt tgccagttac ggagcaagtg agacggcttt tgattgggcg cctgcaccac
       61 ggaagcgcca gacagaagcg aggtgtggaa gctggcagta tgctgttgtt ctgcccgggc
      121 tgcgggaacg gactcattgt ggaggagggg cagcgttgcc atcgcttcgc ctgcaacact
      181 tgcccctacg tccataatat cacccgtaag gtaacaaacc gaaagtatcc aaagctaaaa
      241 gaagtggacg acgtgcttgg tggagcagct gcatgggaga atgtggactc tactgcagag
      301 ccatgtccaa aatgcgaaca tccccgtgcc tacttcatgc agcttcagac gcgttctgca
      361 gacgagccaa tgaccacctt ctataagtgc tgcaatgctc agtgtggaca tcgctggagg
      421 gattaagggc aggacttgcc cagctgcaag catgaatttt gtgtgtactg aaggtctttg
      481 ctatatgata gtaagctgac ttttctgtgg tgaaggatca gggtgaaata taactcatct
      541 gcaagttaac agataaagtc cttgatgtat aggggccgtc aggtccttgg gagatacaca
      601 taaggatgct cacttgggtt caggtcctgt tccttaccat tcaaactagg aacttggttt
      661 atagtcagta aaaataaaaa ttattattat tatttagttt ttcaagacag gttttctctg
      721 tgtagtcctt gctgtccttg ttatgtagac aagtcaacct tgaactcagt gatccacctt
      781 cctctgcctc cagagtgctg gggttaaaag tgtgtgccat gaccaccaat gataaccttg
      841 aaccttctaa tctttttgcc tcttgttgga aaagtgttag ggttataggc atgtgaacta
      901 ttttcatttt atgcagttct ggggattaaa ctctaagcct catgcatgct agataagcat
      961 tctaccaact gagctatatc tctagccctt tttttctttc tagagaaatt atgaaaaata
     1021 cttataaaga tactgaaaaa tcactttaaa agtctggaat tactcgattc atcttgtatg
     1081 attaataact aaacaaaact attctgtgag ttggactttc tggatgattt tgataggaat
     1141 tttaaaaagt aaccaaaacc attttctatt acctgatttg gagaaaggtc tacagtagag
     1201 cttgtgcccc atttgaaccc catccaaaaa tctattttaa cctcaataaa tttagaaaag
     1261 ttacatatta aggctatgtg aagaatgagc ttatatatgg accaacttca gatgagagtg
     1321 tctgagagta tctcagagag ctcacaagca cgaattcctc taacaaacaa gagtaacaga
     1381 aaagttgcat atttgttgaa accactaatg gtattgctct gtaaggtgga catatttgta
     1441 tgtgggaagt cctggtctgt tctgtgtaac tggacagttc tacacatgat aagaaatgta
     1501 gctagtaagg aaatctaaaa taacagattc ctcccatgag tatctgatgt tttcaaaatc
     1561 cttaaatagt gatatagatg aataattcat aaaccaaagc tgactttgaa atttttgatc
     1621 tctggttgct ttcaagcctt tggaactttg ttgcttatct cctttaaata actccgttac
     1681 aaagtagagc cacgaagtct tctttgaatg aggtgtattg agtattaaag cacttgtata
     1741 tgccaagctc tggcctcagt tcttgtactg gatggcagag gtgtgtggaa gaatgaggat
     1801 gtttactgtt ggtgagggtt aggacattct caccttgctg gtgggagtag aagatggtac
     1861 agtataggaa gggaagataa agccccatgc ttctgcctgc gtcaatctca gttcgttcag
     1921 taaacttttc tcagcaaagc tggtattttg attatgtagc aggattttcc ctgtccaatt
     1981 aatttaatta ttaatacaat aagaagcctg tgattggaca gagttgtaga gatagggagc
     2041 cacagaggag aagaggagga agaaaatgga ggacaaacag gacaattcag attctgcgtg
     2101 gctttaaata gccacaggta gctgtagtat agggatagaa taattgggat aacttgtcta
     2161 atctaggtgg gcagcttgta tcatcgattg actctgaaat tattgtgtgg gtatcttgtg
     2221 aattgagaat ttattgatat ataaatctga ctaattataa gcttctagag ttttgatttt
     2281 actgtgttac taggaattgt gacagctaac tggaggtagg tggtcattgc atgggctggt
     2341 gtggcaacaa ccccccaaga gaacttggcg agtcaggtgg agtctgctga gataagaaca
     2401 cccctttcgg gaacttgccg ttctttttaa tatttcccac aacaggatta ggcctcagaa
     2461 aagaatttca caataattgg gtcaagtatc ctaaaaatag ccatgtttat gatttgggtg
     2521 gccttttaag aggattgttc agtaatactc cacccccacc cctattttca gatcacagag
     2581 tgattctgta gataacaagg attcaaacag ttcttaatat atcacgttac aagggagtta
     2641 aggtttaagt tttgactgtc aacaaagaaa ctatctttgt gagttataga cttacagctg
     2701 ggaaaagtta aactcaaagg tcatgtgtta aaacttatta ttggactaga gagatggctc
     2761 agtggtataa gagcactggc tgctcttcta gagttagggt tagttcagtt cacagcagcc
     2821 acacaattgc tcacaaccat ctgtaatggg atccgatgcc ctcttctggt gtgtctgaag
     2881 acagcaacgg tgtactcata cacattaaat taatctttta aaaaa
//
