LOCUS       NM_027241               1427 bp    mRNA    linear   ROD 24-DEC-2024
DEFINITION  Mus musculus polymerase (RNA) III (DNA directed) polypeptide G like
            (Polr3gl), transcript variant 1, mRNA.
ACCESSION   NM_027241
VERSION     NM_027241.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1427)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1427)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1427)
  AUTHORS   Wang,X., Gerber,A., Chen,W.Y. and Roeder,R.G.
  TITLE     Functions of paralogous RNA polymerase III subunits POLR3G and
            POLR3GL in mouse development
  JOURNAL   Proc Natl Acad Sci U S A 117 (27), 15702-15711 (2020)
   PUBMED   32576691
REFERENCE   4  (bases 1 to 1427)
  AUTHORS   Renaud,M., Praz,V., Vieu,E., Florens,L., Washburn,M.P., l'Hote,P.
            and Hernandez,N.
  TITLE     Gene duplication and neofunctionalization: POLR3G and POLR3GL
  JOURNAL   Genome Res 24 (1), 37-51 (2014)
   PUBMED   24107381
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122037.2 and AK008069.1.
            
            On Jun 14, 2014 this sequence version replaced NM_027241.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC027083.1, AK008069.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135, SAMN01164137
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-38                AC122037.2         55922-55959
            39-80               AK008069.1         4-45
            81-386              AK008069.1         47-352
            387-387             AC122037.2         68450-68450
            388-479             AK008069.1         354-445
            480-480             AC122037.2         69611-69611
            481-666             AK008069.1         447-632
            667-679             AC122037.2         70262-70274
            680-1021            AK008069.1         646-987
            1022-1285           AC122037.2         71826-72089
            1286-1425           AK008069.1         1252-1391
            1426-1427           AC122037.2         72230-72231
FEATURES             Location/Qualifiers
     source          1..1427
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 41.93 cM"
     gene            1..1427
                     /gene="Polr3gl"
                     /gene_synonym="2010003I19Rik"
                     /note="polymerase (RNA) III (DNA directed) polypeptide G
                     like"
                     /db_xref="GeneID:69870"
                     /db_xref="MGI:MGI:1917120"
     exon            1..98
                     /gene="Polr3gl"
                     /gene_synonym="2010003I19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            99..266
                     /gene="Polr3gl"
                     /gene_synonym="2010003I19Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             141..797
                     /gene="Polr3gl"
                     /gene_synonym="2010003I19Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     DNA-directed RNA polymerase III subunit RPC7-like; RNA
                     polymerase III subunit C7-like; DNA-directed RNA
                     polymerase III subunit G-like"
                     /codon_start=1
                     /product="DNA-directed RNA polymerase III subunit
                     RPC7-like isoform 1"
                     /protein_id="NP_081517.2"
                     /db_xref="CCDS:CCDS17641.1"
                     /db_xref="GeneID:69870"
                     /db_xref="MGI:MGI:1917120"
                     /translation="MASRGGGRGRGRGQLTFNMEAVGIGKGDALPPPTLQPSPLFPPL
                     EFHPVPLPAGEEGEYVLALKQELRGAMRQLPYFIRPAVPKRDVERYSDKYQMSGPIDN
                     AIDWNPDWRRLPSELKIRVRKVQKERTTIILPKRPPKSTDDKEETIQKLETLEKKEEE
                     VTSEEDEEKEEEEEKEEGEEEEYDEEEHEEETDYIMSYFDNGEDFGGDSDDNMDEAIY
                     "
     exon            267..396
                     /gene="Polr3gl"
                     /gene_synonym="2010003I19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            397..465
                     /gene="Polr3gl"
                     /gene_synonym="2010003I19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            466..522
                     /gene="Polr3gl"
                     /gene_synonym="2010003I19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            523..596
                     /gene="Polr3gl"
                     /gene_synonym="2010003I19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            597..710
                     /gene="Polr3gl"
                     /gene_synonym="2010003I19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            711..1427
                     /gene="Polr3gl"
                     /gene_synonym="2010003I19Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1404..1409
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Polr3gl"
                     /gene_synonym="2010003I19Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1427
                     /gene="Polr3gl"
                     /gene_synonym="2010003I19Rik"
                     /note="major polyA site"
ORIGIN      
        1 gagagctcgg ggaggcgggc ctagaacgag ggctggaaga agaaaagcaa atttcaagtt
       61 ggcggctgcg tgggccctga gtgggggagg gacggcaggt ttttctcact ggatctctgc
      121 atatccaggc cccctccacc atggccagcc ggggtggggg ccggggtcgt ggccggggcc
      181 agttgacctt caacatggag gctgtgggca ttgggaaggg tgatgctttg cccccaccca
      241 ctctccagcc ctctccactc tttcctccct tggagttcca cccagtgcct ctgccggcag
      301 gagaggaggg ggagtatgtc ctggcactga agcaagagct gcgcggggcc atgaggcagc
      361 tcccctactt catccggcca gccgtcccca agagagatgt ggaacgttac tcagacaagt
      421 atcagatgtc tgggcctatt gacaacgcca tcgattggaa ccctgattgg cggcgactcc
      481 ccagtgagct caagattcga gtgcggaaag tacagaagga gcggaccacc attatccttc
      541 ccaagaggcc ccctaagagc acagacgata aggaggagac gatacagaaa ctagagacgc
      601 tagagaagaa ggaggaggaa gtgacttcgg aggaggatga agagaaagaa gaagaggagg
      661 agaaggaaga gggggaggaa gaggaatacg atgaagagga gcatgaggag gaaactgatt
      721 acatcatgtc atattttgac aatggagagg actttggagg ggacagcgat gacaatatgg
      781 atgaggccat atactgaaaa acctgggcat agactgaaaa cctgggccat agactgaaaa
      841 cctgggccca tatatcattc ttgatttgag atacaggaac taaatatccc tatgtactta
      901 ggggttttcc tatttttgtt atttgttttg ttttgttttg gttggttggc ttggtttgtt
      961 ttttccagac aggtttctct gtgtagccct ggctgtcctg gaactcactc tgtagaccag
     1021 gctggcctca aactcagaaa tccgcctgcc tctgcctctg cctctgcctc ccaagtgctg
     1081 ggattaaagg cattcgccac catgcccagc tttgttattg ttttttgaga gaagatctca
     1141 tgtagctcaa gctggcctgg aactcggtat gtagctgagg ctggccttga attttggacc
     1201 cccccccacc cccccaagcc ttgggattac agggacgcgc caccacagca gacttactag
     1261 catttacttc tgttgagaaa aaattggtta gaatccaggt gacctgtgtg atccctgggg
     1321 gctgtgatgc gcagccgttg acagtttagg ggagacttgg ggtgggaaca gtcaagagga
     1381 gtaaggcctg ttttgtactt ttaaataaaa tgtttgtatc tgtctaa
//
