LOCUS       NM_001081176            3060 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus polymerase (RNA) III (DNA directed) polypeptide G
            (Polr3g), mRNA.
ACCESSION   NM_001081176 XM_283153
VERSION     NM_001081176.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3060)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3060)
  AUTHORS   Wang,X., Gerber,A., Chen,W.Y. and Roeder,R.G.
  TITLE     Functions of paralogous RNA polymerase III subunits POLR3G and
            POLR3GL in mouse development
  JOURNAL   Proc Natl Acad Sci U S A 117 (27), 15702-15711 (2020)
   PUBMED   32576691
  REMARK    GeneRIF: Functions of paralogous RNA polymerase III subunits POLR3G
            and POLR3GL in mouse development.
REFERENCE   3  (bases 1 to 3060)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3060)
  AUTHORS   Molyneaux,B.J., Goff,L.A., Brettler,A.C., Chen,H.H., Hrvatin,S.,
            Rinn,J.L. and Arlotta,P.
  TITLE     DeCoN: genome-wide analysis of in vivo transcriptional dynamics
            during pyramidal neuron fate selection in neocortex
  JOURNAL   Neuron 85 (2), 275-288 (2015)
   PUBMED   25556833
  REMARK    Erratum:[Neuron. 2016 Jan 6;89(1):235]
REFERENCE   5  (bases 1 to 3060)
  AUTHORS   Renaud,M., Praz,V., Vieu,E., Florens,L., Washburn,M.P., l'Hote,P.
            and Hernandez,N.
  TITLE     Gene duplication and neofunctionalization: POLR3G and POLR3GL
  JOURNAL   Genome Res 24 (1), 37-51 (2014)
   PUBMED   24107381
REFERENCE   6  (bases 1 to 3060)
  AUTHORS   Wong,R.C., Pollan,S., Fong,H., Ibrahim,A., Smith,E.L., Ho,M.,
            Laslett,A.L. and Donovan,P.J.
  TITLE     A novel role for an RNA polymerase III subunit POLR3G in regulating
            pluripotency in human embryonic stem cells
  JOURNAL   Stem Cells 29 (10), 1517-1527 (2011)
   PUBMED   21898682
  REMARK    GeneRIF: POLR3G is absent in unfertilized oocytes and present
            predominately in the cytoplasm in fertilized zygotes and two cell
            embryos.
REFERENCE   7  (bases 1 to 3060)
  AUTHORS   Taniwaki,T., Haruna,K., Nakamura,H., Sekimoto,T., Oike,Y.,
            Imaizumi,T., Saito,F., Muta,M., Soejima,Y., Utoh,A., Nakagata,N.,
            Araki,M., Yamamura,K. and Araki,K.
  TITLE     Characterization of an exchangeable gene trap using pU-17 carrying
            a stop codon-beta geo cassette
  JOURNAL   Dev Growth Differ 47 (3), 163-172 (2005)
   PUBMED   15840001
REFERENCE   8  (bases 1 to 3060)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 3060)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
REFERENCE   10 (bases 1 to 3060)
  AUTHORS   Wang,Z. and Roeder,R.G.
  TITLE     Three human RNA polymerase III-specific subunits form a subcomplex
            with a selective function in specific transcription initiation
  JOURNAL   Genes Dev 11 (10), 1315-1326 (1997)
   PUBMED   9171375
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC154771.2.
            
            On Feb 6, 2007 this sequence version replaced XM_283153.6.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK009876.1, BC066818.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164137 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-156               AC154771.2         153546-153701       c
            157-306             AC154771.2         142432-142581       c
            307-436             AC154771.2         137336-137465       c
            437-496             AC154771.2         131885-131944       c
            497-547             AC154771.2         129814-129864       c
            548-630             AC154771.2         124800-124882       c
            631-774             AC154771.2         120804-120947       c
            775-3060            AC154771.2         116525-118810       c
FEATURES             Location/Qualifiers
     source          1..3060
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 43.68 cM"
     gene            1..3060
                     /gene="Polr3g"
                     /gene_synonym="2310047G20Rik; RPC32; RPC7"
                     /note="polymerase (RNA) III (DNA directed) polypeptide G"
                     /db_xref="GeneID:67486"
                     /db_xref="MGI:MGI:1914736"
     exon            1..156
                     /gene="Polr3g"
                     /gene_synonym="2310047G20Rik; RPC32; RPC7"
                     /inference="alignment:Splign:2.1.0"
     exon            157..306
                     /gene="Polr3g"
                     /gene_synonym="2310047G20Rik; RPC32; RPC7"
                     /inference="alignment:Splign:2.1.0"
     CDS             190..861
                     /gene="Polr3g"
                     /gene_synonym="2310047G20Rik; RPC32; RPC7"
                     /note="RNA polymerase III subunit C7; DNA-directed RNA
                     polymerase III subunit G"
                     /codon_start=1
                     /product="DNA-directed RNA polymerase III subunit RPC7"
                     /protein_id="NP_001074645.1"
                     /db_xref="CCDS:CCDS36738.1"
                     /db_xref="GeneID:67486"
                     /db_xref="MGI:MGI:1914736"
                     /translation="MAGNKGRGRAAYTFNIEAVGFSRGEKLPDVVLKPPPLFPDTDYK
                     PVPLKTGEDEDYMLALKQELRETVKRLPYFIEPPEEKQDDIERYSKRYMKVYKEEWVP
                     DWRRLPREMMPRKKCKKGDPKSKPSKAAAKATSLINSADVLKTIEELEKRGEGERSDE
                     ENEEKEGSKEKDKDDEEDGEEDAEQEDYDEEEQEEENDYINSYFDNGDDFGVDSDDNM
                     DEATY"
     exon            307..436
                     /gene="Polr3g"
                     /gene_synonym="2310047G20Rik; RPC32; RPC7"
                     /inference="alignment:Splign:2.1.0"
     exon            437..496
                     /gene="Polr3g"
                     /gene_synonym="2310047G20Rik; RPC32; RPC7"
                     /inference="alignment:Splign:2.1.0"
     exon            497..547
                     /gene="Polr3g"
                     /gene_synonym="2310047G20Rik; RPC32; RPC7"
                     /inference="alignment:Splign:2.1.0"
     exon            548..630
                     /gene="Polr3g"
                     /gene_synonym="2310047G20Rik; RPC32; RPC7"
                     /inference="alignment:Splign:2.1.0"
     exon            631..774
                     /gene="Polr3g"
                     /gene_synonym="2310047G20Rik; RPC32; RPC7"
                     /inference="alignment:Splign:2.1.0"
     exon            775..3060
                     /gene="Polr3g"
                     /gene_synonym="2310047G20Rik; RPC32; RPC7"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3032..3037
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Polr3g"
                     /gene_synonym="2310047G20Rik; RPC32; RPC7"
                     /note="hexamer: AATAAA"
     polyA_site      3056
                     /gene="Polr3g"
                     /gene_synonym="2310047G20Rik; RPC32; RPC7"
                     /note="major polyA site"
ORIGIN      
        1 gcggggcttc cagtgcgctc tgctgcgccg tagccgcgtg cggtgtgggg cgcgctactc
       61 cggaggtaga atctgcggct ccttgctgga ggggctgccg gctttcttgc ttcctctgct
      121 gcaccgtgtg ctcaagcctc gagacttggc tagcagcatt ggtccacacg gctgctatag
      181 ctgcttccaa tggctggcaa taaaggaaga gggcgtgctg cctacacctt taatatcgaa
      241 gctgttggat tcagcagagg ggagaagtta cctgatgttg tgttgaagcc tccacccctg
      301 tttcctgata cagactacaa gccggtgccc ctgaaaacgg gagaagatga ggattacatg
      361 ctggccttga agcaggagtt gagggaaaca gtgaaacgat tgccgtactt tattgaacca
      421 cccgaagaaa aacaagatga tattgaaagg tatagcaaac gatacatgaa ggtctataaa
      481 gaagaatggg taccagattg gagaagactt ccaagagaga tgatgccaag gaaaaaatgc
      541 aaaaaagggg atccaaaatc caagccgagc aaagctgcag ccaaggctac atcactcatt
      601 aattctgcag atgtgttgaa aacgattgag gaactggaaa agagaggcga gggtgaaaga
      661 tcggatgaag aaaacgaaga gaaagaaggg agcaaagaga aagataaaga tgatgaggag
      721 gatggcgagg aagatgcaga acaggaggac tacgatgaag aggaacaaga agaggagaat
      781 gactacatta actcctactt cgacaacggc gatgattttg gtgtagacag cgacgacaac
      841 atggatgaag ccacctacta gctgtggaat cctcaaatgt ttgggggatt cagcttcgag
      901 cgtttggacc cactttattt tggataagga ttaagtccgt attttctgtt gttcagtgtt
      961 ctgtatccaa ctcttgagaa cgactttgtg tttacagccc atgaccttac tcccttacct
     1021 ctgccacacc tgtgactatg caatgcggtt gtgggttctc tggcttttgt ttgatctgga
     1081 tttgaatgtt tctagagagt tttcgtggca ctcttgtgtg ttcacagttt aaaaagctca
     1141 ctctggctca cctgctgacc ttcggtagca agggttactc gtcatagtgg atttctctta
     1201 atactgcacg tggggcactt taaaagcaaa ctggacgatg atttctcttc cctggaacat
     1261 tgttttatca cgctgtgacc tcataaactg acctcagaaa cgtccctgag ttcctaacag
     1321 tagagttatg ctgataggaa acaggttctc ggcaagcacc agtgacctgg gtgagaccca
     1381 cttcagtttc cacctcagcc acaacaaaga ctttcacgtg ggtggaaggt tctcaacgct
     1441 tggccttggg gataactcca agccttacag tgtacagtgt gtaaactaat gattccattg
     1501 tagtaagtct gacactttca acttgttggg ctgggacttg tgggagggga agctgagaca
     1561 cactgctcaa ttctggactt aaactggaaa caagtcctgg ttgtgtaaac ctcatgataa
     1621 aatggtgtgt gagtggatat ggtgaagggc actcccctcc tttgtgtttc acaagactca
     1681 taaactgcaa gtcaattata taatcactgt aaaatctcag gtcattttgg aattatgagc
     1741 gattcttctt gttttaactt acagggtgac tctcccctgc agttttctat tttgcaggag
     1801 aaaatatcca gatcccttca cctctgagga ctttaaaaca tgccaaagat tttcaaggga
     1861 attcatagta tgcatttcga aactaacgta ttaacaggat ctgcctacgg gaggaaaatc
     1921 ggtttttccc agtgggagac ttgttactca gtatcctctg accggaaact ggaggcctgc
     1981 ttcttctctc aggatcgaga taaccttaat attaagctta agtttgggtg ccttagtttc
     2041 tccacttgta aatggtttcc tatcaaaatt tataggaaaa tttatagtgt ttagacacta
     2101 accagaattg accaaatatg ctttctttta cgctacagaa acaaccatgt cgtaaattgt
     2161 ttgctctgta cgtagtactg tggacgtgag atagctgtga ggaaccgttt cctgttgagt
     2221 tataattcga tttccagtct tgtacctgtg ttagaaacgg tagtttcttt gtatgatccg
     2281 agagattcca aaagtctttt ctcaggtgaa ggatcacttt caatggcagt gcttctttaa
     2341 atacttcctg atgggttcga gagcccatct tgacagtata ctgctgaacg cttacatcca
     2401 gttcccagga gctgataaag atgctgtgag attcctagtg gaaaccaagt ctttaaagct
     2461 gcagtgtgtt agggaactta ttaagtttta gtaataatgg caaatgctgt tatttgggaa
     2521 taaaaagtac ttcattctct tatgtttgat accggggcca aacaagattc cattcgtaga
     2581 cactctttgg ttgtttcctt ccagtattac aaagccacag ataacttttc cagttgggag
     2641 ccgcactggc agtgagttct ttcccagcat ccactgtctt caagggtgtg cgccttccac
     2701 ccagagggaa gcgctttccc acaggattga ctcggaaacc cttggcatct ctcctaagga
     2761 tgcgcatctt catttgaaag atcagcttac aactctaaac gtactaattt tgaggagaga
     2821 tgagattttc caggctgctt gactaccata aatcttgttt actttagctc tgagtctatg
     2881 aaattacctt gtagagagat aaataagagt actagttaga gaagagtact tactgggact
     2941 ggtgataaaa tatctttaac aatctcgtaa caaaactagt tgcccacatg ctgatttttc
     3001 tgtatttgtt tacacataca aaatttaaaa aaataaaatt ttggccttaa taccaagatg
//
