LOCUS       NM_029763               4160 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus polymerase (RNA) III (DNA directed) polypeptide F
            (Polr3f), mRNA.
ACCESSION   NM_029763
VERSION     NM_029763.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4160)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4160)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4160)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   4  (bases 1 to 4160)
  AUTHORS   Sheehan,S., Tsaih,S.W., King,B.L., Stanton,C., Churchill,G.A.,
            Paigen,B. and DiPetrillo,K.
  TITLE     Genetic analysis of albuminuria in a cross between C57BL/6J and
            DBA/2J mice
  JOURNAL   Am J Physiol Renal Physiol 293 (5), F1649-F1656 (2007)
   PUBMED   17804484
REFERENCE   5  (bases 1 to 4160)
  AUTHORS   Chiu,S., Kim,K., Haus,K.A., Espinal,G.M., Millon,L.V. and
            Warden,C.H.
  TITLE     Identification of positional candidate genes for body weight and
            adiposity in subcongenic mice
  JOURNAL   Physiol Genomics 31 (1), 75-85 (2007)
   PUBMED   17536020
REFERENCE   6  (bases 1 to 4160)
  AUTHORS   Jones,E., Kimura,H., Vigneron,M., Wang,Z., Roeder,R.G. and
            Cook,P.R.
  TITLE     Isolation and characterization of monoclonal antibodies directed
            against subunits of human RNA polymerases I, II, and III
  JOURNAL   Exp Cell Res 254 (1), 163-172 (2000)
   PUBMED   10623476
REFERENCE   7  (bases 1 to 4160)
  AUTHORS   Wang,Z. and Roeder,R.G.
  TITLE     Three human RNA polymerase III-specific subunits form a subcomplex
            with a selective function in specific transcription initiation
  JOURNAL   Genes Dev 11 (10), 1315-1326 (1997)
   PUBMED   9171375
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK029286.1 and AK036166.1.
            
            On Jul 15, 2005 this sequence version replaced NM_029763.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK029286.1, AK036166.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-357               AK029286.1         2-358
            358-3642            AK036166.1         355-3639
            3643-4160           AK029286.1         3644-4161
FEATURES             Location/Qualifiers
     source          1..4160
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 71.02 cM"
     gene            1..4160
                     /gene="Polr3f"
                     /gene_synonym="2810411G20Rik; 3010019O03Rik;
                     3110032A07Rik; RPC39; RPC6"
                     /note="polymerase (RNA) III (DNA directed) polypeptide F"
                     /db_xref="GeneID:70408"
                     /db_xref="MGI:MGI:1924086"
     exon            1..181
                     /gene="Polr3f"
                     /gene_synonym="2810411G20Rik; 3010019O03Rik;
                     3110032A07Rik; RPC39; RPC6"
                     /inference="alignment:Splign:2.1.0"
     CDS             120..1070
                     /gene="Polr3f"
                     /gene_synonym="2810411G20Rik; 3010019O03Rik;
                     3110032A07Rik; RPC39; RPC6"
                     /EC_number="2.7.7.6"
                     /note="RNA polymerase III subunit C6; DNA-directed RNA
                     polymerase III subunit F"
                     /codon_start=1
                     /product="DNA-directed RNA polymerase III subunit RPC6"
                     /protein_id="NP_084039.2"
                     /db_xref="CCDS:CCDS16820.1"
                     /db_xref="GeneID:70408"
                     /db_xref="MGI:MGI:1924086"
                     /translation="MAEVKVKVQPPDADPVEIENRIIELCHQFPHGITDQVIQNEMPH
                     IEAQQRAVAINRLLSMGQLDLLRSNTGLLYRIKDSQNAGKMKGSDNQEKLVYQIIEDA
                     GNKGIWSRDIRYKSNLPLTEINKILKNLESKKLIKAVKSVAASKKKVYMLYNLQPDRS
                     VTGGAWYSDQDFESEFVEVLNQQCFKFLQSKAETARESKQNPVIQRNSSFASSHEVWK
                     YICELGISKVELSMEDIETILNTLIYDGKVEMTIIAAKEGTVGSVDGHMKLYRAVNPI
                     LPPTGVVRAPCGLCPVFEDCHEGGEISPSNCIYMTEWLEF"
     exon            182..299
                     /gene="Polr3f"
                     /gene_synonym="2810411G20Rik; 3010019O03Rik;
                     3110032A07Rik; RPC39; RPC6"
                     /inference="alignment:Splign:2.1.0"
     exon            300..367
                     /gene="Polr3f"
                     /gene_synonym="2810411G20Rik; 3010019O03Rik;
                     3110032A07Rik; RPC39; RPC6"
                     /inference="alignment:Splign:2.1.0"
     exon            368..435
                     /gene="Polr3f"
                     /gene_synonym="2810411G20Rik; 3010019O03Rik;
                     3110032A07Rik; RPC39; RPC6"
                     /inference="alignment:Splign:2.1.0"
     exon            436..548
                     /gene="Polr3f"
                     /gene_synonym="2810411G20Rik; 3010019O03Rik;
                     3110032A07Rik; RPC39; RPC6"
                     /inference="alignment:Splign:2.1.0"
     exon            549..692
                     /gene="Polr3f"
                     /gene_synonym="2810411G20Rik; 3010019O03Rik;
                     3110032A07Rik; RPC39; RPC6"
                     /inference="alignment:Splign:2.1.0"
     exon            693..800
                     /gene="Polr3f"
                     /gene_synonym="2810411G20Rik; 3010019O03Rik;
                     3110032A07Rik; RPC39; RPC6"
                     /inference="alignment:Splign:2.1.0"
     exon            801..992
                     /gene="Polr3f"
                     /gene_synonym="2810411G20Rik; 3010019O03Rik;
                     3110032A07Rik; RPC39; RPC6"
                     /inference="alignment:Splign:2.1.0"
     exon            993..4160
                     /gene="Polr3f"
                     /gene_synonym="2810411G20Rik; 3010019O03Rik;
                     3110032A07Rik; RPC39; RPC6"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2366..2371
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Polr3f"
                     /gene_synonym="2810411G20Rik; 3010019O03Rik;
                     3110032A07Rik; RPC39; RPC6"
                     /note="hexamer: ATTAAA"
     polyA_site      2386
                     /gene="Polr3f"
                     /gene_synonym="2810411G20Rik; 3010019O03Rik;
                     3110032A07Rik; RPC39; RPC6"
                     /note="major polyA site"
     regulatory      3382..3387
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Polr3f"
                     /gene_synonym="2810411G20Rik; 3010019O03Rik;
                     3110032A07Rik; RPC39; RPC6"
                     /note="hexamer: AATAAA"
     regulatory      3393..3398
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Polr3f"
                     /gene_synonym="2810411G20Rik; 3010019O03Rik;
                     3110032A07Rik; RPC39; RPC6"
                     /note="hexamer: AATAAG"
     polyA_site      3407
                     /gene="Polr3f"
                     /gene_synonym="2810411G20Rik; 3010019O03Rik;
                     3110032A07Rik; RPC39; RPC6"
     polyA_site      3411
                     /gene="Polr3f"
                     /gene_synonym="2810411G20Rik; 3010019O03Rik;
                     3110032A07Rik; RPC39; RPC6"
     regulatory      3629..3634
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Polr3f"
                     /gene_synonym="2810411G20Rik; 3010019O03Rik;
                     3110032A07Rik; RPC39; RPC6"
                     /note="hexamer: AATAAA"
     polyA_site      3648
                     /gene="Polr3f"
                     /gene_synonym="2810411G20Rik; 3010019O03Rik;
                     3110032A07Rik; RPC39; RPC6"
ORIGIN      
        1 gaagaaggtc cctcgcctct ctctcaagcc tcggtccccg gcgcgcgcct ccaccggttc
       61 ccgagacttc cagcgcgctc cgaggggcca cttttcctct agtctcgaaa actgccctca
      121 tggcggaggt gaaggtcaag gtgcagccgc cggacgcgga tccggtggag atagaaaaca
      181 gaattataga attatgccac cagttccctc atggaatcac agatcaagta attcagaacg
      241 aaatgcctca cattgaagcc cagcagcggg cagtggccat caatagactg ttatccatgg
      301 gtcagttgga tcttttaagg agtaacacag gcctcttata tagaataaag gattctcaga
      361 atgctggtaa aatgaagggg tccgataacc aggaaaaact ggtctatcaa atcatagagg
      421 atgcagggaa taaaggaata tggagcagag atattcggta caaaagtaac ttgccgttaa
      481 cagaaatcaa caaaattctc aagaatttgg aaagtaaaaa gctaattaaa gccgtgaagt
      541 ctgtagcagc ttccaaaaag aaggtttata tgctctataa cctgcagcca gaccgatctg
      601 tgactggcgg tgcctggtac agtgaccagg attttgaatc tgaatttgtt gaggtgctta
      661 atcaacagtg tttcaaattc ctacaaagca aggcagagac agcaagagaa agtaaacaga
      721 atccagtgat acaaagaaat agttcatttg catcgtcaca tgaagtctgg aagtacatct
      781 gtgagctggg catcagcaag gtagagttgt ccatggagga cattgaaacc atcttgaaca
      841 cactcattta tgatggcaaa gtggagatga ctatcattgc tgcgaaggaa ggcactgttg
      901 gcagcgtaga tggacacatg aaactgtaca gggcagtcaa cccaatcctc ccacctacag
      961 gcgtggtccg ggcaccctgt ggactctgcc ccgtttttga ggactgccat gaaggtggtg
     1021 agatttcgcc gtctaattgt atttacatga cagagtggct tgaattttaa tgagagctgt
     1081 gcactttatc tacatttggc aaactgaact ccatggagaa caaacaattc atgatggagt
     1141 gtaaatttct ttgaaagcat acttcacaat aatggatact gacttgctgc tatgaaaaca
     1201 tttatttatg aagacagaac acaaagcaga ttgagtttaa taaagtttaa ttgggaagtc
     1261 tcttcttcag taagtaaaat accttgaagg tctggaaggc aaggaaaaga agccagcaag
     1321 cctatgttga ccaagtactg agataaaggc tggaacgaga agatgttcac tagagttgct
     1381 tcattgaaaa ctcatcgggg ttattaccac catttgtttg gttgtttttg ggttttgttg
     1441 agaagaaatt acaagtggtg cagacaggaa cagctgatgg catgtgtgcc atcttggggc
     1501 ctgggtagtc aagtgggcat tcctttttca tgccatctgt tgctcttcac cccaggactc
     1561 tttcagggga gtgtgcctcc ataccgacct cactcccaaa tgctgttgta caggacgtgt
     1621 ttccacatca ctgttattcc atgctaaaag aaatagtctc actgttcctt ttttgttaag
     1681 gctatcactt ttctctgtat gccttaattg tattatttcc tgggtttttt tccagattct
     1741 cattccatgc ctgtagtgtg actctctcta ccactagtgc caaattcaaa ttttacagtc
     1801 taaattccag gacagccaga gctatatagg gagagaccca gtctcacaca tacaaataaa
     1861 aatagaacat tgcccttcat tcagtctctg agggttggta accagtattt agctggtgcc
     1921 cttttctctt attcttcaaa acactggtat gacatgtctg agcagaaagc catcactgtg
     1981 tactttctca gtcctggctg ttcggccctg gaaaacatta attggcgtgc tgttgtacag
     2041 aaggtagcct ctgaaggatc tcagctcgtg gattgtctct ttctaaagat ttatttatct
     2101 gtaagtacac tgtagttgtc ttcagacact ccagaagagg gcgtctgatt tcattacaga
     2161 tggttgcaag ccaccatgtg gttgctggga tttgaacttg ggaccttcag aagagcagtc
     2221 agtgctctta atccctgagc cacctcacca gcactcccct cccctttttg ttttgagaca
     2281 gggtttctct atgtagctct gactgtccta gaactctgta gaccaaactc agggatctgc
     2341 ctgcctctac tgcccaagga ctatgattaa agatgcgata cccgcacctg gctctttttt
     2401 ccatttttat ctctcttaca tatttaattt tctagtaagg taagactagt gcttatttga
     2461 taggtcaggc agatcggaca ttgttaccat gccgcacctc acaagaggtg gagggaaaaa
     2521 aaaccctgtg ttttatatat aatctaacac ttaaaatagc tggtgtcatt gaatgcttac
     2581 tcttatagag ctggccatag acttcatctg ataaaagtga actagtgagt ttgattttac
     2641 tcaggtaact aatgatgcta ttcacttaga gcactgtcag aaggtggtag aactcagctc
     2701 cacagaggat cccagtgcaa accctttaag ttggtccatg cttttggctt atataaaaaa
     2761 cttagtacga tcaaacaacc ttagacacga agtaagctga gtatagtgga aagcctttaa
     2821 tcccagtacc caggaggcag aggcaggcag atctaggaca gccagagcta cataaagaaa
     2881 ccctatcttg aggaaccaaa taacaataaa agagagaagt tatcttctag ccagcctggt
     2941 ctacagagtg agttccagga cagccagggc tacacagaaa aaccctgtct cgaaaaaaaa
     3001 gaaaaaagtt gttttggaaa tctgctccgc attctgtttt gttgttagag ataagagcat
     3061 cactccacac tggcctggaa taaacttgat ggcccaggct ggcattgaac tcagttattc
     3121 tgctttagct ttccaagtgc tgggattcca ggcacgcatt tagcagccgg gcctggcttt
     3181 gcattgtctt gataattaga tgagttttta aatcagcact cagtggttag aaatgttcct
     3241 tgcctcacca gaataaagag agcttagata tttttcctca gcattatttt ttactctgag
     3301 tatttttgcc ttgtaatgta tttttttact gtattaactg agaaggatag agaagtctga
     3361 aaatgtagca actgttctgt aaataaagtg ggaataagct atcaaaagaa attgtgggcc
     3421 tctaaaatca taatgtcaca aaatcaaatt gcagatgaag cccagattct tcatactctc
     3481 ccacttagta ctaggccttt tgttcacctg agcacacata ctactaatct gttgaggacc
     3541 ccgtttaaaa gtgatccata aagaagggag acatgaggtg atttagtggt tcttaatgtg
     3601 gattctcaca ttaaactttg aatttggcaa taaataagtt ttaaataagg gttttggtgg
     3661 taattaagca aagtagtcat atcaattctg tgatggacag tgatcgaata ctcctcgtac
     3721 gatgaggcct ctggcccaac catcaaccca acagttaagg ggggaaaagt agtttcagat
     3781 ttactatctg gtaggtgaga gatgaataca aaatatgcgc cctctagcag tatgatccag
     3841 taagacagca tcttgaacag aatcctgcct ctatgttgct cctgcagggt ttataggtat
     3901 gtgccacatc tggacaaata gcattttcta tcatgatgga aatagtcttt atttggtgtt
     3961 tagtccagta accttcagcc agatggctgg ccagcacttg acacaaatga ttaagagcta
     4021 agtttttatt tagttgcctg tgcatactgt ttatattaga cggcacagct caacagagag
     4081 ctctcttgca tactctcccc ctgggaatta ttgaaactca cactgaaatg tgttagttta
     4141 taattaagat ttttaacgtt
//
