LOCUS       NM_028925               2204 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus polymerase (RNA) III (DNA directed) polypeptide C
            (Polr3c), mRNA.
ACCESSION   NM_028925 XM_131049 XM_908475
VERSION     NM_028925.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2204)
  AUTHORS   Saul,M.C., Stevenson,S.A., Zhao,C., Driessen,T.M., Eisinger,B.E.
            and Gammie,S.C.
  TITLE     Genomic variants in an inbred mouse model predict mania-like
            behaviors
  JOURNAL   PLoS One 13 (5), e0197624 (2018)
   PUBMED   29768498
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC112261.4.
            
            On Dec 20, 2022 this sequence version replaced NM_028925.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK016716.1, BC151028.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-127               AC112261.4         53117-53243
            128-293             AC112261.4         54593-54758
            294-549             AC112261.4         56540-56795
            550-735             AC112261.4         56893-57078
            736-821             AC112261.4         57967-58052
            822-926             AC112261.4         61027-61131
            927-1019            AC112261.4         61266-61358
            1020-1100           AC112261.4         63845-63925
            1101-1152           AC112261.4         64112-64163
            1153-1213           AC112261.4         64898-64958
            1214-1364           AC112261.4         65322-65472
            1365-1466           AC112261.4         66232-66333
            1467-1516           AC112261.4         66448-66497
            1517-1666           AC112261.4         66962-67111
            1667-2204           AC112261.4         68532-69069
FEATURES             Location/Qualifiers
     source          1..2204
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 41.96 cM"
     gene            1..2204
                     /gene="Polr3c"
                     /gene_synonym="4933407E01Rik; RPC3; RPC62"
                     /note="polymerase (RNA) III (DNA directed) polypeptide C"
                     /db_xref="GeneID:74414"
                     /db_xref="MGI:MGI:1921664"
     exon            1..127
                     /gene="Polr3c"
                     /gene_synonym="4933407E01Rik; RPC3; RPC62"
                     /inference="alignment:Splign:2.1.0"
     exon            128..293
                     /gene="Polr3c"
                     /gene_synonym="4933407E01Rik; RPC3; RPC62"
                     /inference="alignment:Splign:2.1.0"
     CDS             147..1748
                     /gene="Polr3c"
                     /gene_synonym="4933407E01Rik; RPC3; RPC62"
                     /note="RNA polymerase III subunit C3; DNA-directed RNA
                     polymerase III subunit C"
                     /codon_start=1
                     /product="DNA-directed RNA polymerase III subunit RPC3"
                     /protein_id="NP_083201.1"
                     /db_xref="CCDS:CCDS51010.1"
                     /db_xref="GeneID:74414"
                     /db_xref="MGI:MGI:1921664"
                     /translation="MTQAEIKLCSLLLQEHFGEIVEKIGVHLVRTGSQPLRVIAHDTK
                     ASLDQVKKALCVLIHHNLVLYHVHKRGVVEYEAQCSRVLRMLRYPRYIYTTKTLYGDT
                     GELIVEELLLNGKMTMSAVVKKVADRLTETMEDGKTMDYAEVSNAFVRLADTHFVQRC
                     PLVPDTDSSDRGPPPPAPTLVINEKDMYLVPKLSLIGKGKRRRSSDEDATGEPKAKKP
                     RYTDNKEPSPDDGIYWQVNLDRFHQHFRDQAIVSAVANRMDQTSSEIVRTMLRMSEIT
                     TPSSAPYTQPLSSNEIFRSLPVGYNISKQVLDQYLTLLADDPLEFIGKSGDSGGGMFV
                     INLHKALASLATATLESVIQERFGSRCARIFRLVLQKKHLEQKQVEDFAMIPAKEAKD
                     MLYKMLSENFILLQEIPKTPDHAPSRTFYLYTVNVLSAARMLLHRCYKSIANLIERRQ
                     FETKENKRLLEKSQRVEAIMASMQATGAEEVQLQEIEEMITAPERQQLETLKRNVNKL
                     DASEIQVDETIFLLESYIESTMKRQ"
     exon            294..549
                     /gene="Polr3c"
                     /gene_synonym="4933407E01Rik; RPC3; RPC62"
                     /inference="alignment:Splign:2.1.0"
     exon            550..735
                     /gene="Polr3c"
                     /gene_synonym="4933407E01Rik; RPC3; RPC62"
                     /inference="alignment:Splign:2.1.0"
     exon            736..821
                     /gene="Polr3c"
                     /gene_synonym="4933407E01Rik; RPC3; RPC62"
                     /inference="alignment:Splign:2.1.0"
     exon            822..926
                     /gene="Polr3c"
                     /gene_synonym="4933407E01Rik; RPC3; RPC62"
                     /inference="alignment:Splign:2.1.0"
     exon            927..1019
                     /gene="Polr3c"
                     /gene_synonym="4933407E01Rik; RPC3; RPC62"
                     /inference="alignment:Splign:2.1.0"
     exon            1020..1100
                     /gene="Polr3c"
                     /gene_synonym="4933407E01Rik; RPC3; RPC62"
                     /inference="alignment:Splign:2.1.0"
     exon            1101..1152
                     /gene="Polr3c"
                     /gene_synonym="4933407E01Rik; RPC3; RPC62"
                     /inference="alignment:Splign:2.1.0"
     exon            1153..1213
                     /gene="Polr3c"
                     /gene_synonym="4933407E01Rik; RPC3; RPC62"
                     /inference="alignment:Splign:2.1.0"
     exon            1214..1364
                     /gene="Polr3c"
                     /gene_synonym="4933407E01Rik; RPC3; RPC62"
                     /inference="alignment:Splign:2.1.0"
     exon            1365..1466
                     /gene="Polr3c"
                     /gene_synonym="4933407E01Rik; RPC3; RPC62"
                     /inference="alignment:Splign:2.1.0"
     exon            1467..1516
                     /gene="Polr3c"
                     /gene_synonym="4933407E01Rik; RPC3; RPC62"
                     /inference="alignment:Splign:2.1.0"
     exon            1517..1666
                     /gene="Polr3c"
                     /gene_synonym="4933407E01Rik; RPC3; RPC62"
                     /inference="alignment:Splign:2.1.0"
     exon            1667..2204
                     /gene="Polr3c"
                     /gene_synonym="4933407E01Rik; RPC3; RPC62"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2183..2188
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Polr3c"
                     /gene_synonym="4933407E01Rik; RPC3; RPC62"
                     /note="hexamer: AATAAA"
     polyA_site      2204
                     /gene="Polr3c"
                     /gene_synonym="4933407E01Rik; RPC3; RPC62"
                     /note="major polyA site"
ORIGIN      
        1 ctgacccttc cgcgtccgcc tggatggtgc tctacttcta agaaggggcg atgggaagct
       61 catgagctga ggctgctggc ctcgggagga caacatttgg agcttctaaa ttagccccga
      121 ccctgagttc tgaggctcta agaacgatga ctcaagcaga gattaaactg tgttctttgt
      181 tgctgcaaga gcattttggt gagattgtag aaaaaattgg agtccaccta gtcagaactg
      241 gaagccagcc acttagagta attgcccacg acacaaaagc atccctggac caggtgaaaa
      301 aagccctttg tgtcctcatt caccacaacc tggtcctcta tcatgtgcac aagcgcggtg
      361 tggtggagta tgaagcccag tgcagccggg tactgaggat gcttaggtat ccccggtaca
      421 tctacaccac caaaacgctg tacggtgaca ccggagagct gattgttgag gagctcctgc
      481 tgaatggcaa aatgacaatg tcagctgttg tgaagaaagt agccgaccga ctcacagaga
      541 ccatggagga tggcaagacc atggactacg ctgaggtatc aaatgcattt gtgcgactgg
      601 cagatactca ctttgtacag cgctgtcccc tggttcctga cactgacagt tctgaccgtg
      661 ggccaccgcc acccgcccca acccttgtca ttaatgaaaa ggacatgtac ctagttccca
      721 aactgagctt gataggaaaa ggtaagagga ggagatcatc tgatgaagat gctactggag
      781 agcccaaggc caagaaacca agatacacag ataacaagga gccctcacca gacgatggga
      841 tttattggca agtcaacctc gacaggttcc accagcactt ccgtgaccaa gcaatcgtga
      901 gcgcagtggc aaaccgaatg gaccagacaa gcagcgagat cgtgcggacg atgctccgga
      961 tgagtgagat caccactccc tctagcgccc cctatactca gccgctgtcc tccaatgaga
     1021 tcttcaggtc cctgcccgtc ggatataaca tctctaaaca ggttctcgat cagtacctca
     1081 cgctgctggc agatgaccca ctagagttta ttggaaagtc tggcgacagt ggcggaggaa
     1141 tgtttgtcat caacctccat aaagcattag cgtccctagc cactgcaact ctggagtctg
     1201 tcatccagga gagattcggg tctcgctgtg ccaggatatt ccgtctggta ttgcagaaga
     1261 aacaccttga gcagaagcag gtggaggact ttgcaatgat ccctgcgaag gaggcaaagg
     1321 acatgctgta caagatgctc tcggaaaact tcatcctgct gcaggaaatt cctaagacgc
     1381 cagaccacgc cccgtccagg accttctatc tgtacactgt gaatgtgctc tcagctgcca
     1441 ggatgctgtt gcacaggtgc tataagagca tagccaactt gatagaacgg cgacagtttg
     1501 aaacaaagga gaacaagcgg ctactagaaa agtctcagcg ggtggaagcc atcatggcat
     1561 ccatgcaggc cacgggtgca gaggaggtgc agctgcagga gatagaggag atgatcacag
     1621 cccccgagcg gcagcagctg gagacactga aacgcaacgt taacaagttg gacgccagtg
     1681 agatccaggt ggatgaaacc atcttcttac tggaatcata cattgagagc accatgaaga
     1741 ggcagtgacc cagaagaagc aatgctggga tcaaactcag ggcctttcac atgctagtca
     1801 actgatgttc cactgagcac atccccaacc agaaaccagc atccttctca gaagatctag
     1861 cagatcgagg aggacgagga cgaggaggag gaggaggagg tggtgactag atgagttctt
     1921 tgcagtgaat ttttgtttgt ttctttttcg agacagggtt tctctgtgta gccctggatg
     1981 tcctggaact cactctgtgg accaggctgg cctcaaactc aggatcctcc tgagtgctgg
     2041 gattaaaggc gtacaccacc atgcccagct cggctgcaga ttcttgtact gaccccctat
     2101 tcctgacttt cccagaggct catgatagac ctgaaagagt gtattctcct ctcatcaagt
     2161 cctcacagta tgaggaaccc taaataaatg agaacaatca taaa
//
