LOCUS       NM_001081247            4695 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus polymerase (RNA) III (DNA directed) polypeptide A
            (Polr3a), mRNA.
ACCESSION   NM_001081247 XM_487324
VERSION     NM_001081247.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4695)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4695)
  AUTHORS   Choquet,K., Pinard,M., Yang,S., Moir,R.D., Poitras,C.,
            Dicaire,M.J., Sgarioto,N., Lariviere,R., Kleinman,C.L.,
            Willis,I.M., Gauthier,M.S., Coulombe,B. and Brais,B.
  TITLE     The leukodystrophy mutation Polr3b R103H causes homozygote mouse
            embryonic lethality and impairs RNA polymerase III biogenesis
  JOURNAL   Mol Brain 12 (1), 59 (2019)
   PUBMED   31221184
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4695)
  AUTHORS   Choquet,K., Yang,S., Moir,R.D., Forget,D., Lariviere,R.,
            Bouchard,A., Poitras,C., Sgarioto,N., Dicaire,M.J., Noohi,F.,
            Kennedy,T.E., Rochford,J., Bernard,G., Teichmann,M., Coulombe,B.,
            Willis,I.M., Kleinman,C.L. and Brais,B.
  TITLE     Absence of neurological abnormalities in mice homozygous for the
            Polr3a G672E hypomyelinating leukodystrophy mutation
  JOURNAL   Mol Brain 10 (1), 13 (2017)
   PUBMED   28407788
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4695)
  AUTHORS   Canella,D., Bernasconi,D., Gilardi,F., LeMartelot,G.,
            Migliavacca,E., Praz,V., Cousin,P., Delorenzi,M. and Hernandez,N.
  CONSRTM   CycliX Consortium
  TITLE     A multiplicity of factors contributes to selective RNA polymerase
            III occupancy of a subset of RNA polymerase III genes in mouse
            liver
  JOURNAL   Genome Res 22 (4), 666-680 (2012)
   PUBMED   22287103
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154573.2.
            
            On Apr 17, 2018 this sequence version replaced NM_001081247.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC151002.1, AK170475.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-186               AC154573.2         168320-168505       c
            187-322             AC154573.2         165834-165969       c
            323-460             AC154573.2         165565-165702       c
            461-632             AC154573.2         164234-164405       c
            633-787             AC154573.2         163827-163981       c
            788-1027            AC154573.2         161083-161322       c
            1028-1190           AC154573.2         160806-160968       c
            1191-1327           AC154573.2         160553-160689       c
            1328-1431           AC154573.2         157460-157563       c
            1432-1573           AC154573.2         157187-157328       c
            1574-1714           AC154573.2         155620-155760       c
            1715-1784           AC154573.2         153185-153254       c
            1785-1912           AC154573.2         152267-152394       c
            1913-2051           AC154573.2         151981-152119       c
            2052-2216           AC154573.2         150712-150876       c
            2217-2389           AC154573.2         148382-148554       c
            2390-2501           AC154573.2         146708-146819       c
            2502-2620           AC154573.2         145699-145817       c
            2621-2758           AC154573.2         145001-145138       c
            2759-2929           AC154573.2         143147-143317       c
            2930-3043           AC154573.2         141411-141524       c
            3044-3130           AC154573.2         138666-138752       c
            3131-3213           AC154573.2         138464-138546       c
            3214-3384           AC154573.2         137311-137481       c
            3385-3478           AC154573.2         136302-136395       c
            3479-3571           AC154573.2         136017-136109       c
            3572-3736           AC154573.2         134618-134782       c
            3737-3901           AC154573.2         133958-134122       c
            3902-4033           AC154573.2         133640-133771       c
            4034-4166           AC154573.2         132142-132274       c
            4167-4695           AC154573.2         130141-130669       c
FEATURES             Location/Qualifiers
     source          1..4695
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 14.4 cM"
     gene            1..4695
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /note="polymerase (RNA) III (DNA directed) polypeptide A"
                     /db_xref="GeneID:218832"
                     /db_xref="MGI:MGI:2681836"
     exon            1..186
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     CDS             143..4315
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /EC_number="2.7.7.6"
                     /codon_start=1
                     /product="DNA-directed RNA polymerase III subunit RPC1"
                     /protein_id="NP_001074716.1"
                     /db_xref="CCDS:CCDS36828.1"
                     /db_xref="GeneID:218832"
                     /db_xref="MGI:MGI:2681836"
                     /translation="MVKEQFRETDVAKKISHICFGMKSPEEMRQQAHIQVVSKNLYSQ
                     DNNHAPLLYGVLDHRMGTSEKDRPCETCGKNLADCLGHYGYIDLELPCFHVGYFRAVI
                     GILQMICKTCCHIMLSQEEKQQFLDFLKRPGLTYLQKRGLKKKISDKCRKKSTCHYCG
                     AFNGTVKKCGLLKIIHEKYKTNKKVVDPIVSNFLQSFETAIEHNKEVEPLLGRAQENL
                     NPLVVLNLFKRIPAEDVPLLLMNPESGKPSDLILTRLLVPPLCIRPSVVSDLKSGTNE
                     DDLTMKLTEIIFLNDVIKKHRISGAKTQMIMEDWDFLQLQCALYINSELSGIPLNMAP
                     KKWTRGFVQRLKGKQGRFRGNLSGKRVDFSGRTVISPDPNLRIDEVAVPVHVAKILTF
                     PEKVNKANINFLRKLVRNGPDVHPGANFIQQRHMQMKRFLKYGNREKMAQELKFGDIV
                     ERHLIDGDVVLFNRQPSLHKLSIMAHLARVKPHRTFRFNECVCTPYNADFDGDEMNLH
                     LPQTEEAKAEALVLMGTKANLVTPRNGEPLIAAIQDFLTGAYLLTLKDTFFDRAKACQ
                     IIASILVGKDEKIKVRLPPPTILKPVTLWTGKQIFSVILRPSDDNPVRANLRTKGKQY
                     CGKGEDLCVNDSYVTIQNSELMCGSMDKGTLGSGSKNNIFYILLRDWGQNEAADAMSR
                     LARLAPVYLSNRGFSIGIGDVTPGQGLLKAKYELLNAGYKKCDEYIEALNTGKLQQQP
                     GCTAEETLEALILKELSVIRDHAGSACLRELDKSNSPLTMALCGSKGSFINISQMIAC
                     VGQQAISGSRVPDGFENRSLPHFEKHSKLPAAKGFVANSFYSGLTPTEFFFHTMAGRE
                     GLVDTAVKTAETGYMQRRLVKSLEDLCSQYDLTVRSSTGDIIQFIYGGDGLDPAAMEG
                     KDEPLEFKRVLDNIKAVYPCQTEPALSKNDLTLTAEAIMKKNEFLCCQDSFLQEIKTF
                     IKGVSEKIKKTRDKYGINDNGTTEPRVLYQLDRITPTQIEKFLETCRDKYMRAQMEPG
                     SAVGALCAQSIGEPGTQMTLKTFHFAGVASMNITLGVPRIKEIINASKAISTPIITAQ
                     LDKDDDADYARLVKGRIEKTLLGEISEYIEEVFLPDDCFILVKLSLERIRLLRLEVNA
                     ETVRYSICTSKLRVKPGDVAVHGEAVVCVTPRENSKSSMYYVLQFLKEDLPKVVVQGI
                     PEVSRAVIHIDEQSGKEKFKLLVEGDNLRAVMATHGVKGTRTTSNNTYEVEKTLGIEA
                     ARTTIINEIQYTMVNHGMSIDRRHVMLLSDLMTYKGEVLGITRFGLAKMKESVLMLAS
                     FEKTADHLFDAAYFGQKDSVCGVSECIIMGIPMNIGTGLFKLLHKANRDPKPPRRPLI
                     FDTHEFHIPLVT"
     exon            187..322
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            323..460
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            461..632
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            633..787
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            788..1027
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            1028..1190
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            1191..1327
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            1328..1431
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            1432..1573
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            1574..1714
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            1715..1784
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            1785..1912
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            1913..2051
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            2052..2216
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            2217..2389
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            2390..2501
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            2502..2620
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            2621..2758
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            2759..2929
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            2930..3043
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            3044..3130
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            3131..3213
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            3214..3384
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            3385..3478
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            3479..3571
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            3572..3736
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            3737..3901
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            3902..4033
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            4034..4166
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     exon            4167..4695
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4663..4668
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /note="hexamer: AATACA"
     polyA_site      4695
                     /gene="Polr3a"
                     /gene_synonym="9330175N20Rik; RPC1; RPC155"
                     /note="major polyA site"
ORIGIN      
        1 agcggcacgt gcggcgctct acggtggccg gggaggctgc tgcagcttcc ttactcctaa
       61 atacctaagc accccgggaa ggtgcggcga cagtggtttt tgtagtcgca gctccgagaa
      121 gggcgtccgg ccagccggca ccatggtgaa ggagcagttc cgcgagacgg atgtggctaa
      181 gaaaataagc catatctgtt ttggaatgaa gtcccctgag gagatgcgcc agcaggcaca
      241 tatccaggtt gtcagtaaga acctgtacag ccaagacaac aaccacgccc ccttgttgta
      301 tggagtgctt gaccatagaa tgggtacgag cgaaaaagat cgtccttgtg agacctgtgg
      361 gaagaacttg gcggactgtc tcggccacta tggctacatt gatctcgagc taccgtgctt
      421 tcatgtcggg tacttcaggg ctgtcattgg tatcttacag atgatctgca aaacctgctg
      481 ccacattatg ctgtcccagg aagagaagca gcagtttcta gattttctga agaggcctgg
      541 cctaacctac ctgcagaagc gaggcctgaa gaagaagatc tcagataaat gccggaagaa
      601 aagcacttgt cactactgtg gtgcctttaa tggtaccgta aagaaatgtg gtttactgaa
      661 gataattcat gaaaaataca agacaaacaa aaaagtcgtg gatcccattg tatcaaactt
      721 cctgcagtcc tttgagacag ccattgagca taacaaagag gttgaacccc tgctgggaag
      781 ggcccaggag aacttgaatc ctttagtagt tctgaacttg tttaagcgca tcccagctga
      841 agatgtcccg ttactcctga tgaacccaga atctggaaag ccctctgatt tgattctcac
      901 ccgacttttg gtgcctcccc tgtgtatcag accgtccgtc gtgagtgatc tgaagtctgg
      961 aaccaatgaa gatgacctga caatgaaact gacagagatc attttcctaa atgatgttat
     1021 taaaaagcac cggatctccg gagccaagac gcagatgatc atggaggact gggatttcct
     1081 gcagctgcag tgtgccctct acatcaacag tgagctctct ggcatccctc tcaacatggc
     1141 acctaagaaa tggacgcgag gctttgtgca gcgcctgaag gggaaacagg gtcgatttag
     1201 aggtaatctg tcagggaaga gggtggattt ctccggccga acagtcatct cacctgaccc
     1261 caacctccgg attgatgaag tagccgtgcc agttcatgtg gccaaaattc taacttttcc
     1321 tgagaaggtg aacaaagcaa acatcaactt tttgaggaaa ctggttcgaa atggcccaga
     1381 tgttcaccca ggagccaatt ttatccaaca aagacacatg cagatgaaga ggttcctgaa
     1441 gtatggaaat cgggaaaaga tggctcagga gctcaagttc ggcgacattg tagagagaca
     1501 cctgatagat ggagatgtgg tcttgttcaa ccggcagccc tccctgcaca aactgagcat
     1561 catggcccac ctggccaggg ttaagcccca ccggaccttc agattcaatg aatgtgtctg
     1621 caccccctac aatgcagact ttgatgggga tgaaatgaac cttcatcttc cccagacaga
     1681 ggaagccaaa gcagaggccc ttgttctcat ggggaccaaa gcgaaccttg taaccccacg
     1741 aaatggggag ccactcattg ctgccattca ggacttctta acaggtgctt acctcctcac
     1801 cctcaaggac accttctttg accgagccaa ggcttgccag atcatcgctt caatactggt
     1861 tggcaaagat gaaaaaatta aagtgcgcct cccaccccct acaatactaa agcctgtcac
     1921 cctgtggacc ggaaagcaga tcttcagtgt catcctcaga cctagtgatg acaatccagt
     1981 gcgggccaac ctccgaacca agggcaagca gtactgtggc aagggggaag acctctgcgt
     2041 caacgactcc tatgtcacca tccagaacag tgagttgatg tgcggcagca tggacaaagg
     2101 gaccctgggg tcggggtcca agaacaacat cttctacatc ttgctacgag actgggggca
     2161 gaatgaggct gccgatgcca tgtctcggct tgccaggctg gctcctgtct acctgtctaa
     2221 ccgtgggttc tccatcggga ttggtgatgt cacgcctggc cagggactgc tgaaagccaa
     2281 gtatgagcta ctaaatgctg gctacaaaaa atgtgacgag tacattgaag ccctgaacac
     2341 aggcaagctg cagcagcagc caggctgcac ggccgaggag acgcttgagg ctctgatcct
     2401 gaaggagctg tctgtgatcc gggaccatgc tggcagtgcc tgcctccgcg agctggacaa
     2461 gagcaacagc cccctcacca tggccctgtg tggctccaaa ggttccttca taaacatatc
     2521 acagatgatt gcctgtgtgg gacagcaagc catcagtggc tcccgggttc cagatggctt
     2581 tgagaacaga tctttgcctc actttgagaa gcattcaaag ctccctgctg ccaaaggctt
     2641 tgtggccaat agcttttact ctggcttaac gcctactgag tttttcttcc acacaatggc
     2701 cggtcgggag ggtctggtgg acacagctgt aaagactgct gaaacaggat acatgcagag
     2761 aagactggtc aaatccctgg aagacctctg ctcgcagtac gatctgacag tgcggagctc
     2821 caccggtgac atcatccagt tcatctatgg aggagatggc ttagatcctg ctgccatgga
     2881 gggcaaagac gaaccgctgg agtttaagcg ggttctggac aacatcaagg cagtgtatcc
     2941 atgtcagact gaacctgctc tcagtaagaa cgacctcacc ttgaccgctg aggccatcat
     3001 gaagaagaat gagttcctat gctgccaaga cagcttcctg caggaaataa aaacattcat
     3061 taaaggggtg tccgagaaga ttaagaaaac cagagataaa tatgggatca atgataacgg
     3121 cacaacagag cctcgtgtgc tgtaccagtt ggaccgtatt acccctaccc aaatagagaa
     3181 gtttctggag acctgtaggg ataagtatat gagagcacag atggagccag gctctgcggt
     3241 aggtgcactc tgtgcacaga gcattggtga gcccggcacc cagatgacgc tgaagacatt
     3301 ccactttgca ggagtagcct ccatgaacat caccctgggt gtgcctcgga tcaaagagat
     3361 catcaacgct tccaaggcca tcagcactcc aattatcaca gcacagctag acaaggatga
     3421 cgacgcggat tatgcacgcc tggtgaaggg caggattgag aaaaccctcc tgggggagat
     3481 ctcagagtat attgaagaag tgtttcttcc tgatgactgc tttattcttg tcaagctctc
     3541 cctggaacgg atccgacttc tgagactgga ggtcaatgct gagacagtgc ggtactccat
     3601 ctgcacatcc aagctccgag tgaagcctgg tgatgtggcc gttcatgggg aggctgtggt
     3661 gtgtgtcacc cccagggaaa acagcaagag ctccatgtat tatgtgctgc agtttctcaa
     3721 agaggatctg cccaaggtgg ttgtacaagg catcccagag gtgtcgcgag ctgtcatcca
     3781 tattgacgag cagagtggga aggagaagtt caagcttctg gtggaaggtg acaacctgcg
     3841 ggcagtcatg gccacccacg gtgtgaaagg cacccggacc acgtctaata acacctatga
     3901 ggtggaaaaa accctgggca ttgaggctgc ccggacaact atcatcaacg agatccagta
     3961 cacgatggtc aaccacggca tgagcatcga caggaggcac gtgatgctgc tctctgacct
     4021 gatgacctac aagggtgaag tcctgggtat aaccaggttt ggcctggcca agatgaagga
     4081 gagtgtgttg atgctggcct cctttgaaaa gacagctgac catctctttg atgctgccta
     4141 ctttgggcag aaagactctg tatgcggagt gtctgagtgc atcatcatgg gaatcccgat
     4201 gaacatcgga actgggctct tcaagctgtt acacaaagcc aacagggacc ccaaaccacc
     4261 caggagaccc ctgatatttg acacacatga attccacatc cctcttgtta catagtttgt
     4321 ggcaagaggt caccatctct gaccttgatc cttgtcctat gtgctgctga atggaagaac
     4381 tttgttttac ttgaacagat gtctgcataa atttaccatg gtcagacaaa gtccatgccc
     4441 tcagcaggag ctccttggat gggaactggg attctcttca ctgagggacc tcaacactgc
     4501 tgctcagcca gctcacgacc cctgccatct cactgttgct gcagaggatt gtaaggtgtg
     4561 cccatacctg catgtgagcc aggctggccc acagagacta ggacccagtc ctggtttctc
     4621 aatgctcagt tataccagat tttccactga tgtaccaatg taaatacatt acctttattt
     4681 atttgttctg aggga
//
