LOCUS       NM_153798               3812 bp    mRNA    linear   ROD 05-AUG-2024
DEFINITION  Mus musculus polymerase (RNA) II (DNA directed) polypeptide B
            (Polr2b), mRNA.
ACCESSION   NM_153798
VERSION     NM_153798.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3812)
  AUTHORS   Feng,Z., Liu,S., Su,M., Song,C., Lin,C., Zhao,F., Li,Y., Zeng,X.,
            Zhu,Y., Hou,Y., Ren,C., Zhang,H., Yi,P., Ji,Y., Wang,C., Li,H.,
            Ma,M., Luo,L. and Li,L.
  TITLE     TANGO6 regulates cell proliferation via COPI vesicle-mediated RPB2
            nuclear entry
  JOURNAL   Nat Commun 15 (1), 2371 (2024)
   PUBMED   38490996
  REMARK    GeneRIF: TANGO6 regulates cell proliferation via COPI
            vesicle-mediated RPB2 nuclear entry.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3812)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 3812)
  AUTHORS   Kraemer,N., Neubert,G., Issa,L., Ninnemann,O., Seiler,A.E. and
            Kaindl,A.M.
  TITLE     Reference genes in the developing murine brain and in
            differentiating embryonic stem cells
  JOURNAL   Neurol Res 34 (7), 664-668 (2012)
   PUBMED   22735032
  REMARK    GeneRIF: For mouse embryonic stem cells with induced neural
            differentiation, all strategies used in parallel indicate RpII to
            be expressed in a stable manner.
REFERENCE   4  (bases 1 to 3812)
  AUTHORS   Canella,D., Bernasconi,D., Gilardi,F., LeMartelot,G.,
            Migliavacca,E., Praz,V., Cousin,P., Delorenzi,M. and Hernandez,N.
  CONSRTM   CycliX Consortium
  TITLE     A multiplicity of factors contributes to selective RNA polymerase
            III occupancy of a subset of RNA polymerase III genes in mouse
            liver
  JOURNAL   Genome Res 22 (4), 666-680 (2012)
   PUBMED   22287103
REFERENCE   5  (bases 1 to 3812)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   6  (bases 1 to 3812)
  AUTHORS   Cobellis,G., Nicolaus,G., Iovino,M., Romito,A., Marra,E.,
            Barbarisi,M., Sardiello,M., Di Giorgio,F.P., Iovino,N., Zollo,M.,
            Ballabio,A. and Cortese,R.
  TITLE     Tagging genes with cassette-exchange sites
  JOURNAL   Nucleic Acids Res 33 (4), e44 (2005)
   PUBMED   15741177
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 3812)
  AUTHORS   Kabe,Y., Yamada,J., Uga,H., Yamaguchi,Y., Wada,T. and Handa,H.
  TITLE     NF-Y is essential for the recruitment of RNA polymerase II and
            inducible transcription of several CCAAT box-containing genes
  JOURNAL   Mol Cell Biol 25 (1), 512-522 (2005)
   PUBMED   15601870
  REMARK    GeneRIF: NF-Y recruits RNAPII and general transcription factors
            onto various CCAAT box-containing promoters to permit strong
            transcriptional activation independently of histone modifications
REFERENCE   8  (bases 1 to 3812)
  AUTHORS   Sharov,A.A., Piao,Y., Matoba,R., Dudekula,D.B., Qian,Y.,
            VanBuren,V., Falco,G., Martin,P.R., Stagg,C.A., Bassey,U.C.,
            Wang,Y., Carter,M.G., Hamatani,T., Aiba,K., Akutsu,H., Sharova,L.,
            Tanaka,T.S., Kimber,W.L., Yoshikawa,T., Jaradat,S.A., Pantano,S.,
            Nagaraja,R., Boheler,K.R., Taub,D., Hodes,R.J., Longo,D.L.,
            Schlessinger,D., Keller,J., Klotz,E., Kelsoe,G., Umezawa,A.,
            Vescovi,A.L., Rossant,J., Kunath,T., Hogan,B.L., Curci,A.,
            D'Urso,M., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Transcriptome analysis of mouse stem cells and early embryos
  JOURNAL   PLoS Biol 1 (3), E74 (2003)
   PUBMED   14691545
REFERENCE   9  (bases 1 to 3812)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   10 (bases 1 to 3812)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK039766.1, CN690754.1, CF155991.1, CF553167.1, BQ177004.1 and
            AA501042.1.
            
            On Apr 18, 2009 this sequence version replaced NM_153798.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC016415.1, AK039766.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1497              AK039766.1         2-1498
            1498-2103           CN690754.1         22-627
            2104-2586           CF155991.1         91-573
            2587-3273           CF553167.1         26-712
            3274-3808           BQ177004.1         19-553              c
            3809-3812           AA501042.1         76-79
FEATURES             Location/Qualifiers
     source          1..3812
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 41.66 cM"
     gene            1..3812
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /note="polymerase (RNA) II (DNA directed) polypeptide B"
                     /db_xref="GeneID:231329"
                     /db_xref="MGI:MGI:2388280"
     exon            1..147
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     CDS             129..3653
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /EC_number="2.7.7.6"
                     /EC_number="2.7.7.48"
                     /note="RNA polymerase II subunit 2; RNA polymerase II
                     subunit B2; DNA-directed RNA polymerase II subunit B;
                     DNA-directed RNA polymerase II 140 kDa polypeptide; 3'-5'
                     exoribonuclease; RNA-directed RNA polymerase II subunit
                     RPB2"
                     /codon_start=1
                     /product="DNA-directed RNA polymerase II subunit RPB2"
                     /protein_id="NP_722493.2"
                     /db_xref="CCDS:CCDS51528.1"
                     /db_xref="GeneID:231329"
                     /db_xref="MGI:MGI:2388280"
                     /translation="MYDADEDMQYDEDDDEITPDLWQEACWIVISSYFDEKGLVRQQL
                     DSFDEFIQMSVQRIVEDAPPIDLQAEAQHASGEVEEPPRYLLKFEQIYLSKPTHWERD
                     GAPSPMMPNEARLRNLTYSAPLYVDITKTVIKEGEEQLQTQHQKTFIGKIPIMLRSTY
                     CLLNGLTDRDLCELNECPLDPGGYFIINGSEKVLIAQEKMATNTVYVFAKKDSKYAYT
                     GECRSCLENSSRPTSTIWVSMLARGGQGAKKSAIGQRIVATLPYIKQEVPIIIVFRAL
                     GFVSDRDILEHIIYDFEDPEMMEMVKPSLDEAFVIQEQNVALNFIGSRGAKPGVTKEK
                     RIKYAKEVLQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLAALGRRELDDRDHYGNKR
                     LDLAGPLLAFLFRGMFKNLLKEVRIYAQKFIDRGKDFNLELAIKTRIISDGLKYSLAT
                     GNWGDQKKAHQARAGVSQVLNRLTFASTLSHLRRLNSPIGRDGKLAKPRQLHNTLWGM
                     VCPAETPEGHAVGLVKNLALMAYISVGSQPSPILEFLEEWSMENLEEISPAAIADATK
                     IFVNGCWVGIHKDPEQLMNTLRKLRRQMDIIVSEVSMIRDIREREIRIYTDAGRICRP
                     LLIVEKQKLLLKKRHIDQLKEREYNNYSWQDLVASGVVEYIDTLEEETVMLAMTPDDL
                     QEKEVAYCSTYTHCEIHPSMILGVCASIIPFPDHNQSPRNTYQSAMGKQAMGVYITNF
                     HVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINSIVAIASYTGYNQEDSVIMNR
                     SAVDRGFFRSVFYRSYKEQESKKGFDQEEVFEKPTRETCQGMRHAIYEKLDDDGLIAP
                     GVRVSGDDVIIGKTVTLPENEDELESTNRRYTKRDCSTFLRTSETGIVDQVMVTLNQE
                     GYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMPFTCEGITPDIIINPHAI
                     PSRMTIGHLIECLQGKVSANKGEIGDATPFNDAVNVQKISNLLSDYGYHLRGNEVLYN
                     GFTGRKITSQIFIGPTYYQRLKHMVDDKIHSRARGPIQILNRQPMEGRSRDGGLRFGE
                     MERDCQIAHGAAQFLRERLFEASDPYQVHVCNLCGIMAIANTRTHTYECRGCRNKTQI
                     SLVRMPYACKLLFQELMSMSIAPRMMSV"
     exon            148..220
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            221..371
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            372..484
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            485..704
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            705..863
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            864..1028
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1029..1225
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1226..1345
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1346..1532
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1533..1676
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1677..1816
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1817..1928
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1929..2083
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            2084..2282
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            2283..2451
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            2452..2548
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            2549..2643
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            2644..2894
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            2895..2984
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            2985..3092
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            3093..3206
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            3207..3367
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            3368..3563
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            3564..3812
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3788..3793
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /note="hexamer: AATAAA"
     polyA_site      3808
                     /gene="Polr2b"
                     /gene_synonym="Pol2rb; Rpb140; Rpb2"
                     /note="major polyA site"
ORIGIN      
        1 gagacgccga ggattctggg aacgtcggag acggacattg cttggtatcg cactcttgag
       61 tttgccgccg cgcttcccgt ctccagcttt gcgattccga gtaagagctc cagaaacctt
      121 tggccaagat gtatgacgcc gacgaggaca tgcaatatga tgaagacgac gatgagatca
      181 ctccggatct gtggcaggaa gcatgctgga tcgtgatcag ttcttacttt gatgagaaag
      241 gcttggtcag acaacagctg gattcctttg atgagtttat tcagatgtct gttcaaagaa
      301 ttgtggaaga tgcaccaccg attgacctac aggccgaagc tcagcacgcc agtggagaag
      361 ttgaagagcc gccaagatat ttactgaagt ttgaacaaat ttacctctcc aaacctactc
      421 attgggaaag agatggtgcc ccttcgccaa tgatgccaaa tgaagccagg ttaagaaatc
      481 tcacgtattc tgctccgctt tacgttgaca taacaaagac agtcattaaa gaaggtgaag
      541 aacagctgca gactcagcac cagaaaacgt tcatagggaa aattccaatt atgctgcgct
      601 ccacctactg cctgttaaat ggcttaacag atcgtgacct gtgtgagctg aatgagtgtc
      661 ctttggatcc cggtggctat tttattatca atggatcaga aaaggttctg atagctcaag
      721 agaaaatggc aacaaacaca gtctatgtgt ttgccaaaaa ggattccaag tatgcctata
      781 caggagaatg tcgctcatgc ctggagaatt cttcccgacc caccagtact atatgggtta
      841 gcatgctggc cagaggagga cagggtgcaa agaagagtgc tattggccag cgcatcgtgg
      901 caacgttacc atacatcaag caagaagttc ctatcatcat tgtgttcaga gcactaggct
      961 ttgtgtctga tagagatatt ttagaacaca tcatttatga cttcgaggat ccagagatga
     1021 tggaaatggt taaaccatct ctcgatgaag cgtttgtcat ccaagagcag aatgttgcct
     1081 taaacttcat cggttcaaga ggggcaaagc ctggtgttac taaggagaaa agaattaaat
     1141 atgcaaaaga agtcttacag aaagaaatgc tccctcacgt tggtgtcagt gatttctgtg
     1201 agaccaaaaa ggcctatttc ttggggtata tggttcatag gttgcttcta gcagccctag
     1261 gcagaagaga actagacgac agagatcact atggcaacaa gagattggat cttgctgggc
     1321 ctctgcttgc attcttattc agaggcatgt ttaagaattt gctgaaagaa gtacgaatct
     1381 atgcgcagaa gtttattgat cgcgggaagg attttaactt agagctggca atcaagacaa
     1441 ggatcatatc tgatgggcta aaatactctt tagccactgg gaactggggt gaccagaaga
     1501 aagctcatca agccagagct ggagtatccc aggtattgaa ccgcctgacg tttgcatcta
     1561 ctctttctca cctgcgtcgt ctaaactctc ctattggcag agatggcaag ctagcgaagc
     1621 ccagacagtt gcataatacc ttgtggggaa tggtgtgtcc tgctgaaact ccagagggcc
     1681 atgctgtagg gcttgtgaag aatttagccc tgatggctta tatttcagtt ggatctcaac
     1741 cctctccaat tttggaattt ttagaagaat ggagcatgga aaatttagaa gaaatttctc
     1801 ctgcagctat tgctgatgca accaagattt ttgttaatgg ctgctgggtt ggaatccata
     1861 aagaccccga acaactcatg aacacgctaa ggaagttacg gcggcagatg gacatcattg
     1921 tatccgaagt ttctatgatc agagatattc gagagcggga gattcggatc tatacagatg
     1981 caggccgtat ttgtagaccc cttctgattg tggaaaagca gaagctgctt ttgaagaaga
     2041 gacacattga ccagttgaaa gagagagaat ataacaacta cagttggcag gatctggtag
     2101 ccagtggggt agtagagtat attgataccc tggaagagga gaccgtgatg cttgcaatga
     2161 ctccagatga tttgcaggag aaggaagtag cttattgttc tacctacacc cactgtgaga
     2221 ttcacccatc aatgattctt ggagtctgtg catctattat tccttttcct gatcataacc
     2281 agtcccctag aaacacatac cagtctgcta tgggcaagca ggctatggga gtttatatca
     2341 ccaacttcca tgtgcggatg gacaccttgg cccatgttct ctactatcct cagaaacccc
     2401 ttgtgactac acggtctatg gaatatctac gattcagaga gctgccagca ggaatcaact
     2461 caattgtggc cattgcatcc tacacgggct ataatcaaga agactctgtt atcatgaatc
     2521 gttcagctgt ggatcgaggc tttttcaggt ctgttttcta ccgatcatac aaagaacaag
     2581 agtctaaaaa gggatttgat caagaagaag tgtttgagaa gcctacacgt gagacatgcc
     2641 agggaatgag gcatgccatc tatgaaaagt tggacgatga cggtttgata gctccggggg
     2701 tccgagtctc cggagatgac gttattatcg gcaagacagt caccttaccc gagaacgagg
     2761 atgagctgga gagcaccaac aggcgctaca ccaagaggga ctgcagcact ttcctcagaa
     2821 ctagtgagac gggcatcgtg gaccaggtca tggtcactct caaccaggaa ggatataaat
     2881 tttgtaaaat aagggtgcgc tctgttagaa ttccgcagat tggagacaaa tttgctagcc
     2941 gacatggtca gaagggaact tgtggtattc agtatagaca agaggacatg ccgttcactt
     3001 gcgaaggcat aactcctgac atcatcataa acccccacgc catcccctcc cggatgacaa
     3061 ttggtcactt gatcgaatgt ctccaaggga aggtctctgc caacaagggt gaaattggtg
     3121 acgctactcc atttaatgat gctgtcaatg tgcagaagat ttctaatctt ttgtctgact
     3181 atggctacca tctcagaggg aacgaggtgc tctacaatgg attcactgga cgaaaaatca
     3241 catcacagat ttttattggc cccacttact accagcgttt gaagcatatg gtggatgaca
     3301 aaattcattc tcgtgctagg ggacccattc agattcttaa cagacagccc atggagggca
     3361 gatctcgtga tggtggcctg cgcttcggag aaatggaacg agactgtcaa attgcccacg
     3421 gtgcagcaca gtttctaaga gaaagactgt ttgaagcatc agatccgtat caggttcatg
     3481 tctgtaatct ttgtggaata atggcaattg ctaacacgag gactcataca tatgagtgca
     3541 ggggatgccg caataaaacc cagatttcct tggtgcgaat gccgtacgcg tgcaagctgt
     3601 tgttccagga gctcatgtcc atgagcatcg caccacgaat gatgagtgtt tagctgccag
     3661 aagttcatgg tcagatactg tgactatcac tatcttgttt ctgtgattgt cattaaaaaa
     3721 aaatttactg ttgtgataag aattttattt gttttgttta aagctacatg tgcttttttc
     3781 tgtaaataat aaatttttgt agatagtctt ga
//
