LOCUS       NM_001347327            2089 bp    mRNA    linear   ROD 09-JUN-2024
DEFINITION  Mus musculus podocalyxin-like 2 (Podxl2), transcript variant 1,
            mRNA.
ACCESSION   NM_001347327 XM_006506246
VERSION     NM_001347327.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2089)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2089)
  AUTHORS   Hsia,H.E., Tushaus,J., Feng,X., Hofmann,L.I., Wefers,B.,
            Marciano,D.K., Wurst,W. and Lichtenthaler,S.F.
  TITLE     Endoglycan (PODXL2) is proteolytically processed by ADAM10 (a
            disintegrin and metalloprotease 10) and controls neurite branching
            in primary neurons
  JOURNAL   FASEB J 35 (9), e21813 (2021)
   PUBMED   34390512
REFERENCE   3  (bases 1 to 2089)
  AUTHORS   Yang,Z., Zimmerman,S.E., Tsunezumi,J., Braitsch,C., Trent,C.,
            Bryant,D.M., Cleaver,O., Gonzalez-Manchon,C. and Marciano,D.K.
  TITLE     Role of CD34 family members in lumen formation in the developing
            kidney
  JOURNAL   Dev Biol 418 (1), 66-74 (2016)
   PUBMED   27542690
REFERENCE   4  (bases 1 to 2089)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643. PMID: 29144450]
REFERENCE   5  (bases 1 to 2089)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   6  (bases 1 to 2089)
  AUTHORS   Trinidad,J.C., Specht,C.G., Thalhammer,A., Schoepfer,R. and
            Burlingame,A.L.
  TITLE     Comprehensive identification of phosphorylation sites in
            postsynaptic density preparations
  JOURNAL   Mol Cell Proteomics 5 (5), 914-922 (2006)
   PUBMED   16452087
REFERENCE   7  (bases 1 to 2089)
  AUTHORS   van der Zwaag,B., Burbach,J.P., Scharfe,C., Oefner,P.J.,
            Brunner,H.G., Padberg,G.W. and van Bokhoven,H.
  TITLE     Identifying new candidate genes for hereditary facial paresis on
            chromosome 3q21-q22 by RNA in situ hybridization in mouse
  JOURNAL   Genomics 86 (1), 55-67 (2005)
   PUBMED   15953540
REFERENCE   8  (bases 1 to 2089)
  AUTHORS   Doyonnas,R., Nielsen,J.S., Chelliah,S., Drew,E., Hara,T.,
            Miyajima,A. and McNagny,K.M.
  TITLE     Podocalyxin is a CD34-related marker of murine hematopoietic stem
            cells and embryonic erythroid cells
  JOURNAL   Blood 105 (11), 4170-4178 (2005)
   PUBMED   15701716
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC153923.4.
            
            On Mar 25, 2020 this sequence version replaced NM_001347327.1.
            
            Transcript Variant: This variant (1) encodes isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7652917.1266588.1,
                                           SRR11927932.3812194.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164137
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-128               AC153923.4         201235-201362       c
            129-401             AC153923.4         191333-191605       c
            402-1195            AC153923.4         175511-176304       c
            1196-1270           AC153923.4         175051-175125       c
            1271-1427           AC153923.4         171849-172005       c
            1428-1489           AC153923.4         171382-171443       c
            1490-1669           AC153923.4         169823-170002       c
            1670-2089           AC153923.4         168873-169292       c
FEATURES             Location/Qualifiers
     source          1..2089
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 39.6 cM"
     gene            1..2089
                     /gene="Podxl2"
                     /gene_synonym="D130074J02Rik; PODLX2"
                     /note="podocalyxin-like 2"
                     /db_xref="GeneID:319655"
                     /db_xref="MGI:MGI:2442488"
     exon            1..128
                     /gene="Podxl2"
                     /gene_synonym="D130074J02Rik; PODLX2"
                     /inference="alignment:Splign:2.1.0"
     exon            129..401
                     /gene="Podxl2"
                     /gene_synonym="D130074J02Rik; PODLX2"
                     /inference="alignment:Splign:2.1.0"
     exon            402..1195
                     /gene="Podxl2"
                     /gene_synonym="D130074J02Rik; PODLX2"
                     /inference="alignment:Splign:2.1.0"
     exon            1196..1270
                     /gene="Podxl2"
                     /gene_synonym="D130074J02Rik; PODLX2"
                     /inference="alignment:Splign:2.1.0"
     exon            1271..1427
                     /gene="Podxl2"
                     /gene_synonym="D130074J02Rik; PODLX2"
                     /inference="alignment:Splign:2.1.0"
     exon            1428..1489
                     /gene="Podxl2"
                     /gene_synonym="D130074J02Rik; PODLX2"
                     /inference="alignment:Splign:2.1.0"
     exon            1490..1669
                     /gene="Podxl2"
                     /gene_synonym="D130074J02Rik; PODLX2"
                     /inference="alignment:Splign:2.1.0"
     exon            1670..2089
                     /gene="Podxl2"
                     /gene_synonym="D130074J02Rik; PODLX2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2056..2061
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Podxl2"
                     /gene_synonym="D130074J02Rik; PODLX2"
                     /note="hexamer: ATTAAA"
     polyA_site      2089
                     /gene="Podxl2"
                     /gene_synonym="D130074J02Rik; PODLX2"
                     /note="major polyA site"
ORIGIN      
        1 gctttgcgcg cccccgaggc cggcccgggc gccgcggcgc tgcggctgcg ggcggcaacg
       61 ctgcaccatg gcccggccgc tgcgggccgc ccgactgccg ccgccgctgc tgttgctgct
      121 ggccgccgga gcttccctgg gtgcctatgc agtgggcgtg gatgagcctg gccccgaggg
      181 cctcacctcc acgtccctgc tggacctctt gttgcccact gactttgagc cactggactc
      241 agaggaaccc agcgaggcca tgggtctaga cgccggccta gccccaggct cgggcttccc
      301 cagtgaggac agcgaggagt cccggctcct gcagccgcca cagtacttct gggaagaaga
      361 ggaactaaac ggctccagcc tggacctggg tcccactgca gactacgtct tcccagacct
      421 gactgagaag gtggcgtcca tggaagaccc aggccaggct ccggacctgc caaacctccc
      481 ctccatcctg cccaagatgg atcttgctga gcctccctgg catatgcctc tgcaggagga
      541 ggaagaggag gaggaagagg aggaggagga aagggaagaa gaggagaggg agaaggaagc
      601 agaggaggag gaggaagagg aagagctgct ccctgtgagc gggtccccag gagccaccgc
      661 acaggcccat gccccttcac ctagcaccag cagcagcacc agcagccaga gtcctggggc
      721 cacccggcac aggcaggagg attctggaga ccaggccaca tcaggcatgg aagtggagag
      781 cagtgtgaaa cccaccttgt cagtgccctc agtcacccca agtacagtgg ccccgggggt
      841 tcagaactat agccaggagt ctgggggcac tgagtggcca actggggggc tgggggtcca
      901 gtctgaggtt ccccagggag ctggtgaggg ggccacagtg ggagcagctg acttcgatgg
      961 ccagcagggg gcactgccgt cctcttcact cccacaaaca gtgcctccaa gtgggactga
     1021 ggtccccagt gagggtcccc tttaccccag aatcccagac tctctcccac ctggacccca
     1081 agacacagag tcaacccctt cctctgctac ctggggacaa gaaggtctca gtgagcagcc
     1141 cctggagggt caggcagctg aagctcactc actaacaccg tgggactcta ctcaggtgat
     1201 ctgcaaggat tggagcaacc tggccgggaa gagctacatc atcctgaaca tgacagagaa
     1261 catagactgt gaagtatttc ggcggcaccg gggactacgg ctcctagctc tggtggagga
     1321 ggtactgcca cgccaccgca gtggccatcg tggagactgg catatttctc tgagcaagcc
     1381 cagtgagaaa gagcaacacc tgctgatgac ccttgtagga gaacagggcg tggtacccac
     1441 tcaagatgtc ctttccatgc tcagtggcat ccgcaggagt ctggaggaga ttggcatcca
     1501 gaactactcc accaccagca gctgccaggc acgagccacc caggtgcgca gtgactacgg
     1561 gacgctcttt gtagtgctgg tgatcattgg tgtcatctgc ttcatcatca ttgtgcttgg
     1621 cctactctac aattgttggc agcgccggat gcccaagctc aaacacgtgt cgcacggtga
     1681 ggagctgcgc ttcgtggaga acggctgcca cgacaatccc acgctggacg tggccagcga
     1741 cagccagtcg gagatgcagg agaagcagcc cagcctgaac ggtggggcca tcaacggccc
     1801 gagcagctgg agcgcgctca tgggcagcaa acgcgaccct gaggactcgg acgtgttcga
     1861 ggaggacact cacctgtgag cgccgggcca cgggcgcgag actgcccgac gccacggccc
     1921 cgcgcccctc ccggtcctcc acgcggacca ctatgcttcc ccaccgcagc aggcgaccgc
     1981 ggcgcagctc ccaccccgcc ctgcccggcc ccgagcgctt gcccgaggcc agcgcgctcc
     2041 ccgcgccagg actccattaa agccgctaag acgcgcgggc cgctccgcc
//
