LOCUS       NM_026173               3033 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus POC5 centriolar protein (Poc5), mRNA.
ACCESSION   NM_026173
VERSION     NM_026173.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3033)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3033)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   3  (bases 1 to 3033)
  AUTHORS   Suzuki,H., Fukunishi,Y., Kagawa,I., Saito,R., Oda,H., Endo,T.,
            Kondo,S., Bono,H., Okazaki,Y. and Hayashizaki,Y.
  TITLE     Protein-protein interaction panel using mouse full-length cDNAs
  JOURNAL   Genome Res 11 (10), 1758-1765 (2001)
   PUBMED   11591653
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK150656.1 and AK004769.2.
            
            On Jul 18, 2009 this sequence version replaced NM_026173.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK150656.1, AK004769.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-72                AK150656.1         2-73
            73-3015             AK004769.2         1-2943
            3016-3033           AK150656.1         3017-3034
FEATURES             Location/Qualifiers
     source          1..3033
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 50.56 cM"
     gene            1..3033
                     /gene="Poc5"
                     /gene_synonym="1200014M14Rik"
                     /note="POC5 centriolar protein"
                     /db_xref="GeneID:67463"
                     /db_xref="MGI:MGI:1914713"
     exon            1..238
                     /gene="Poc5"
                     /gene_synonym="1200014M14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            239..378
                     /gene="Poc5"
                     /gene_synonym="1200014M14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            379..466
                     /gene="Poc5"
                     /gene_synonym="1200014M14Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             389..2065
                     /gene="Poc5"
                     /gene_synonym="1200014M14Rik"
                     /note="protein of centriole 5; POC5 centriolar protein
                     homolog"
                     /codon_start=1
                     /product="centrosomal protein POC5"
                     /protein_id="NP_080449.1"
                     /db_xref="CCDS:CCDS26703.1"
                     /db_xref="GeneID:67463"
                     /db_xref="MGI:MGI:1914713"
                     /translation="MSSDEDKCSLHVAHNDSDRSVSTDLQEEYEELLRYAIVNPNVEC
                     SASQPSHLRGEVAPDRFPTLAGNNPVRDTELEVGKGSDLNISSHSKSGSPRKPSHPVM
                     DFFSSHVLGDSSSPASLSTRTDAHEINGGEHLVSDENFQKLENILDIWSSGLKTNVLS
                     ELSKWRLNFIDWHRMEMKKEKEKHAVVVKQLSNQISDLKELQKAFEISIGRKDEVISN
                     LSRAIGKQKERIELMKSFFRWRIGHVKSRQEIYEGKLADQYFQRTLLKKVWKGWRSVV
                     QRQWKDVVERACQARAEEVCVQISNDYEARLAMLSGALENAKAEIQKMQQEKDHFEDS
                     MKKAFMRGVCALNLEAMTIFQNKNEAGIDFTNNKKEESGPGGPGREPSAHLDTSSSTM
                     PSAVPSQLLPSGPLAAGVASATAFPSAASLTSAGATSASSLHVPISILSAGSAAAPAP
                     EESYAPRVVTAAQQKAGKTITARITGRSDFGSKARINSSLAIMGVSPPMGSVVVEKHH
                     PVTVQTIPQATAAKYPRTIHPESSISASRSLGARPGHAQSLSVQSIKVVD"
     exon            467..584
                     /gene="Poc5"
                     /gene_synonym="1200014M14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            585..662
                     /gene="Poc5"
                     /gene_synonym="1200014M14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            663..853
                     /gene="Poc5"
                     /gene_synonym="1200014M14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            854..1030
                     /gene="Poc5"
                     /gene_synonym="1200014M14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1031..1135
                     /gene="Poc5"
                     /gene_synonym="1200014M14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1136..1315
                     /gene="Poc5"
                     /gene_synonym="1200014M14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1316..1469
                     /gene="Poc5"
                     /gene_synonym="1200014M14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1470..1747
                     /gene="Poc5"
                     /gene_synonym="1200014M14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1748..1924
                     /gene="Poc5"
                     /gene_synonym="1200014M14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1925..3033
                     /gene="Poc5"
                     /gene_synonym="1200014M14Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2282..2287
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Poc5"
                     /gene_synonym="1200014M14Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2300
                     /gene="Poc5"
                     /gene_synonym="1200014M14Rik"
     regulatory      2996..3001
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Poc5"
                     /gene_synonym="1200014M14Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3019
                     /gene="Poc5"
                     /gene_synonym="1200014M14Rik"
                     /note="major polyA site"
ORIGIN      
        1 agttagggct gtctttcatc agggccctca gtttgaaact gtcaagtggc tgctagggga
       61 gccgctgtgc ttgctttggt tgcggcggcg acgccgtctg tcgcagcgag tcaggagccg
      121 aggtttcgcc gagacggtgg atcccggtgg cggcgcccag gccggttcct ccctggcagg
      181 attgggagca tcgtccctgg aggtgccaga aagagaagac acaagtgatg cgaactaaat
      241 gagtaaatcc ataggagccc agggatactg actcctgcgt gcccacaaac ccgatgctcc
      301 agaggcaacc tcatgccggc acagctggta ctgaacttgc tgaccttcca gttccattgt
      361 gctaccgtcc ttgcttcgtg tttgcagaat gtcatctgat gaggacaagt gttcacttca
      421 tgtggctcac aatgactctg accgttctgt ctccacagac cttcaggagg agtatgaaga
      481 gctgcttcgc tatgctattg tgaatccaaa tgttgaatgc agtgcttcgc agccatctca
      541 ccttagagga gaagtggcac cggatagatt ccctacgcta gctggaaata accctgtaag
      601 agacactgaa ctggaagtgg gaaaaggatc cgatttaaat atttcaagcc attcaaaatc
      661 agggtcaccc aggaagccat ctcacccagt catggacttt ttcagctcac atgttttagg
      721 tgactcttcc tcgccagcct ctctttctac tcggacagat gcccatgaaa taaatggggg
      781 ggagcatctc gtctctgatg aaaattttca gaagttggag aatatacttg atatctggag
      841 ttcaggtctt aagacgaacg ttttgtctga gctgagtaag tggaggctga actttatcga
      901 ctggcaccga atggagatga agaaggagaa ggaaaagcat gcggtggtcg tgaagcagct
      961 gtcaaaccag atctcggacc tgaaggagct gcagaaagcc tttgagatct ccatcgggag
     1021 aaaggatgag gtgatttcca acctgtctcg tgccatcggc aagcaaaagg agaggataga
     1081 gttaatgaaa agcttcttcc gctggaggat cggccatgtc aaatccagac aggaaattta
     1141 tgaaggtaaa ctggctgacc agtactttca gagaactttg ctgaagaaag tctggaaggg
     1201 ctggcgctct gtggtacaga ggcagtggaa agatgtggtg gaacgtgcgt gccaagcgag
     1261 ggctgaagaa gtatgtgtgc agatctccaa tgattatgaa gccagactag ctatgttatc
     1321 tggagctttg gaaaatgcaa aggctgagat tcaaaaaatg cagcaggaaa aagaccattt
     1381 cgaagactcc atgaagaaag cattcatgcg gggagtgtgt gcattaaatc tggaggccat
     1441 gaccatattt cagaacaaaa atgaggcagg gatagacttc acaaataata aaaaggaaga
     1501 gagtggccct ggcggtcccg gaagagagcc ttctgctcac ttggatactt cttcgtccac
     1561 gatgccgtca gcagttccgt cacagctgct gccctctgga ccattagcag caggagtagc
     1621 cagtgccact gcctttccct ccgctgcttc cctgacctcg gccggagcta catcggcctc
     1681 ttctcttcac gttcccatct ctattctcag tgcaggatct gcagctgctc ctgccccaga
     1741 ggaatcgtac gcaccaagag tcgtgaccgc agcccagcag aaagctggga agacaattac
     1801 agcccggatc acaggtcggt ctgattttgg ttccaaagct agaatcaaca gcagtttggc
     1861 gataatggga gtctctcctc ccatgggctc agtcgttgtg gagaaacatc atccagtcac
     1921 agtgcaaacc attcctcagg caactgctgc caagtaccca cggaccatcc atcctgaaag
     1981 cagcatctcc gcttctaggt ctctcggagc caggccgggc cacgcccagt ctctctcagt
     2041 tcagtcgata aaagtggttg actagagggg ctgtgttcac actcatggct atgagtcctc
     2101 tgataaggac tttcctggga gcagcaagct tcttggtttt gacttttctg tactgtcaga
     2161 gcatcatgga catatcatgt gcatcttctc agaattacaa gagacttccc catcctttgt
     2221 aactgtatgt atagattatt ttaatgttat ttttatttaa acaattaagt agaacttttt
     2281 aattaaaaca aacaaaaaaa ccttggttct aagcatgtac agcctgccag tgattgccat
     2341 tgtggaagaa tataaatctt ttctggacat tatttccaaa aggaaatcat ttccattgtt
     2401 gctgggcagt aatttacata gagctttgga agggacttta ctttcattac taaaactaat
     2461 agaaggtctt ttaactttta aataaagacc aagagtagca gtgacatttc taaccagagc
     2521 tttcctgcct tcgctgtatg ggccttcatc cctcaggctc tggaattaaa cacggaggga
     2581 aacaaacaac atctgtaaat attcataagg ctaaaaggga agaaagtttc taattagcac
     2641 caaaacagaa aggaattccc tgctggaata agcctgcttt catttctctt gcctgtctca
     2701 ctgagcctgc ctagttcttt ttgctcatcc acacatgtgc tgcagaggag tggcgctttg
     2761 agacagcaga catgggtaag cttaatggcc agccagtgtg aatagacttg ctaggccagg
     2821 cctgatgctg catggttttt atcccaccac gggggatctc tgtgaggcca gcctgatcta
     2881 cagagtgagg tctgtctcag aaagaagaaa gcaagcatct atgcagagct gacgtaggag
     2941 aaaaagcttc ttcgtggctt tcttgctggc tgtgttctct taagccagac attttaataa
     3001 atggatttca aggtcctcat ctgtgatgta agt
//
