LOCUS       NM_001123371            1223 bp    mRNA    linear   ROD 06-SEP-2023
DEFINITION  Mus musculus purine-nucleoside phosphorylase 2 (Pnp2), mRNA.
ACCESSION   NM_001123371 XM_992876 XM_992906
VERSION     NM_001123371.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1223)
  AUTHORS   Fan KQ, Li YY, Wang HL, Mao XT, Guo JX, Wang F, Huang LJ, Li YN, Ma
            XY, Gao ZJ, Chen W, Qian DD, Xue WJ, Cao Q, Zhang L, Shen L, Zhang
            L, Tong C, Zhong JY, Lu W, Lu L, Ren KM, Zhong G, Wang Y, Tang M,
            Feng XH, Chai RJ and Jin J.
  TITLE     Stress-Induced Metabolic Disorder in Peripheral CD4+ T Cells Leads
            to Anxiety-like Behavior
  JOURNAL   Cell 179 (4), 864-879 (2019)
   PUBMED   31675497
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK008143.1.
            
            On Aug 22, 2013 this sequence version replaced NM_001123371.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK008143.1, CK031142.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1223              AK008143.1         5-1227
FEATURES             Location/Qualifiers
     source          1..1223
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 26.32 cM"
     gene            1..1223
                     /gene="Pnp2"
                     /note="purine-nucleoside phosphorylase 2"
                     /db_xref="GeneID:667034"
                     /db_xref="MGI:MGI:3712328"
     exon            1..88
                     /gene="Pnp2"
                     /inference="alignment:Splign:2.1.0"
     CDS             33..950
                     /gene="Pnp2"
                     /codon_start=1
                     /product="purine-nucleoside phosphorylase 2"
                     /protein_id="NP_001116843.1"
                     /db_xref="CCDS:CCDS49479.1"
                     /db_xref="GeneID:667034"
                     /db_xref="MGI:MGI:3712328"
                     /translation="MEQKGQDLGASVGDTIEKEFTYEDYETTAKWLLQHTEYRPQVAV
                     ICGSGLGGLTAHLKAAQIFDYNEIPNFPQSTVQGHAGRLVFGLLNGRSCVMMQGRFHM
                     YEGYSLSEVTFPVRVFHLLGVETLVVTNAAGGLNPNFEVGDIMLIRDHINLPGFCGQN
                     PLRGPNDERFGVRFPAMSDAYDRDMRQKAFSAWKQMGEQRKLQEGTYVMLAGPNFETV
                     AESRLLKMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNMVVMDYENLEKANHKEVL
                     DAGKAAAQKLERFVSILMESIPLPECNLL"
     exon            89..258
                     /gene="Pnp2"
                     /inference="alignment:Splign:2.1.0"
     exon            259..362
                     /gene="Pnp2"
                     /inference="alignment:Splign:2.1.0"
     exon            363..538
                     /gene="Pnp2"
                     /inference="alignment:Splign:2.1.0"
     exon            539..729
                     /gene="Pnp2"
                     /inference="alignment:Splign:2.1.0"
     exon            730..1223
                     /gene="Pnp2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aacagtcttg acctgactca gacagtgtca ccatggagca gaaagggcaa gatttgggcg
       61 cctctgtcgg tgacaccata gagaaagagt tcacatacga agattatgag accactgcca
      121 agtggcttct gcaacacact gaatatcgac ctcaagtggc agtgatctgt ggttccggct
      181 taggagggct gactgctcac ttaaaggcgg ctcagatctt tgactacaat gagataccca
      241 actttcccca aagcacagtg caaggtcacg caggccgact ggtgtttgga ttgctgaatg
      301 gcagatcctg tgtgatgatg caaggccggt tccatatgta tgaaggatac tcactgtcag
      361 aggtgacatt cccagtgaga gttttccatc ttctgggtgt ggaaactttg gtggtcacca
      421 atgctgctgg aggactcaac cccaattttg aagttggaga tattatgctg atccgtgatc
      481 acatcaacct acctggtttc tgtggccaga accctctccg gggccccaac gatgaaaggt
      541 ttggagttcg ttttcctgcc atgtctgatg cttatgaccg ggatatgagg cagaaggctt
      601 tcagtgcctg gaaacaaatg ggggagcaac gaaagctaca agaaggcacc tatgtgatgt
      661 tggcaggtcc caactttgag actgtggcag agagtcgtct gctaaagatg ctgggggcag
      721 atgctgttgg catgagcaca gtcccagaag ttatcgtcgc aaggcactgt gggcttcgtg
      781 tctttggttt ctcactcatt acgaacatgg ttgtcatgga ttatgagaac ttggagaagg
      841 ccaatcacaa ggaagttctg gatgccggga aagcagctgc acagaaattg gaaaggtttg
      901 tctccattct tatggagagc attccactcc cggagtgtaa cctcctttag cctaggcagg
      961 ctggttcaga ctgtatgcca ctgaggtggg gccacctgat gtgctgcttc tctaattcaa
     1021 ctagtttctt ttgatttgac actgccttca cctgccctga ggctgaagtg cttctccaag
     1081 attttctgga gttaacaaca acctgtgaat ctgtcgaatt gctgctaaaa ggctgtgctg
     1141 atgacatcaa gaaacttggt gtgactcggg aggggtttcc ctctttataa gcacagactt
     1201 ttattaaaca tttgaacctt gag
//
