LOCUS       NM_001199352            1506 bp    mRNA    linear   ROD 29-JUL-2024
DEFINITION  Mus musculus pregnancy upregulated non-ubiquitously expressed CaM
            kinase (Pnck), transcript variant 3, mRNA.
ACCESSION   NM_001199352
VERSION     NM_001199352.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1506)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1506)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1506)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643. PMID: 29144450]
REFERENCE   4  (bases 1 to 1506)
  AUTHORS   Combes,A.N., Lesieur,E., Harley,V.R., Sinclair,A.H., Little,M.H.,
            Wilhelm,D. and Koopman,P.
  TITLE     Three-dimensional visualization of testis cord morphogenesis, a
            novel tubulogenic mechanism in development
  JOURNAL   Dev Dyn 238 (5), 1033-1041 (2009)
   PUBMED   19334288
REFERENCE   5  (bases 1 to 1506)
  AUTHORS   Visel,A., Carson,J., Oldekamp,J., Warnecke,M., Jakubcakova,V.,
            Zhou,X., Shaw,C.A., Alvarez-Bolado,G. and Eichele,G.
  TITLE     Regulatory pathway analysis by high-throughput in situ
            hybridization
  JOURNAL   PLoS Genet 3 (10), 1867-1883 (2007)
   PUBMED   17953485
REFERENCE   6  (bases 1 to 1506)
  AUTHORS   Hook,S.S. and Means,A.R.
  TITLE     Ca(2+)/CaM-dependent kinases: from activation to function
  JOURNAL   Annu Rev Pharmacol Toxicol 41, 471-505 (2001)
   PUBMED   11264466
  REMARK    Review article
REFERENCE   7  (bases 1 to 1506)
  AUTHORS   Gardner,H.P., Rajan,J.V., Ha,S.I., Copeland,N.G., Gilbert,D.J.,
            Jenkins,N.A., Marquis,S.T. and Chodosh,L.A.
  TITLE     Cloning, characterization, and chromosomal localization of Pnck, a
            Ca(2+)/calmodulin-dependent protein kinase
  JOURNAL   Genomics 63 (2), 279-288 (2000)
   PUBMED   10673339
REFERENCE   8  (bases 1 to 1506)
  AUTHORS   Peters,H., Wilm,B., Sakai,N., Imai,K., Maas,R. and Balling,R.
  TITLE     Pax1 and Pax9 synergistically regulate vertebral column development
  JOURNAL   Development 126 (23), 5399-5408 (1999)
   PUBMED   10556064
REFERENCE   9  (bases 1 to 1506)
  AUTHORS   Ueda,T., Sakagami,H., Abe,K., Oishi,I., Maruo,A., Kondo,H.,
            Terashima,T., Ichihashi,M., Yamamura,H. and Minami,Y.
  TITLE     Distribution and intracellular localization of a mouse homologue of
            Ca2+/calmodulin-dependent protein kinase Ibeta2 in the nervous
            system
  JOURNAL   J Neurochem 73 (5), 2119-2129 (1999)
   PUBMED   10537072
REFERENCE   10 (bases 1 to 1506)
  AUTHORS   Chodosh,L.A., D'Cruz,C.M., Gardner,H.P., Ha,S.I., Marquis,S.T.,
            Rajan,J.V., Stairs,D.B., Wang,J.Y. and Wang,M.
  TITLE     Mammary gland development, reproductive history, and breast cancer
            risk
  JOURNAL   Cancer Res 59 (7 Suppl), 1765-1771s (1999)
   PUBMED   10197594
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK158755.1, BC051996.1 and CD776443.1.
            
            Transcript Variant: This variant (3) contains a different alternate
            exon in the 5' UTR, compared to variant 1. Variants 1, 2, and 3
            encode the same protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC051996.1, AK158755.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-17                AK158755.1         2-18
            18-1486             BC051996.1         1-1469
            1487-1506           CD776443.1         1-20                c
FEATURES             Location/Qualifiers
     source          1..1506
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 37.38 cM"
     gene            1..1506
                     /gene="Pnck"
                     /gene_synonym="Bstk3; Camk1b; CaMKIbeta2; caMKlb1;
                     CaMKlb2; Punc"
                     /note="pregnancy upregulated non-ubiquitously expressed
                     CaM kinase"
                     /db_xref="GeneID:93843"
                     /db_xref="MGI:MGI:1347357"
     exon            1..52
                     /gene="Pnck"
                     /gene_synonym="Bstk3; Camk1b; CaMKIbeta2; caMKlb1;
                     CaMKlb2; Punc"
                     /inference="alignment:Splign:2.1.0"
     exon            53..122
                     /gene="Pnck"
                     /gene_synonym="Bstk3; Camk1b; CaMKIbeta2; caMKlb1;
                     CaMKlb2; Punc"
                     /inference="alignment:Splign:2.1.0"
     exon            123..254
                     /gene="Pnck"
                     /gene_synonym="Bstk3; Camk1b; CaMKIbeta2; caMKlb1;
                     CaMKlb2; Punc"
                     /inference="alignment:Splign:2.1.0"
     exon            255..329
                     /gene="Pnck"
                     /gene_synonym="Bstk3; Camk1b; CaMKIbeta2; caMKlb1;
                     CaMKlb2; Punc"
                     /inference="alignment:Splign:2.1.0"
     exon            330..468
                     /gene="Pnck"
                     /gene_synonym="Bstk3; Camk1b; CaMKIbeta2; caMKlb1;
                     CaMKlb2; Punc"
                     /inference="alignment:Splign:2.1.0"
     exon            469..592
                     /gene="Pnck"
                     /gene_synonym="Bstk3; Camk1b; CaMKIbeta2; caMKlb1;
                     CaMKlb2; Punc"
                     /inference="alignment:Splign:2.1.0"
     exon            593..668
                     /gene="Pnck"
                     /gene_synonym="Bstk3; Camk1b; CaMKIbeta2; caMKlb1;
                     CaMKlb2; Punc"
                     /inference="alignment:Splign:2.1.0"
     exon            669..781
                     /gene="Pnck"
                     /gene_synonym="Bstk3; Camk1b; CaMKIbeta2; caMKlb1;
                     CaMKlb2; Punc"
                     /inference="alignment:Splign:2.1.0"
     exon            782..860
                     /gene="Pnck"
                     /gene_synonym="Bstk3; Camk1b; CaMKIbeta2; caMKlb1;
                     CaMKlb2; Punc"
                     /inference="alignment:Splign:2.1.0"
     exon            861..948
                     /gene="Pnck"
                     /gene_synonym="Bstk3; Camk1b; CaMKIbeta2; caMKlb1;
                     CaMKlb2; Punc"
                     /inference="alignment:Splign:2.1.0"
     exon            949..1093
                     /gene="Pnck"
                     /gene_synonym="Bstk3; Camk1b; CaMKIbeta2; caMKlb1;
                     CaMKlb2; Punc"
                     /inference="alignment:Splign:2.1.0"
     exon            1094..1488
                     /gene="Pnck"
                     /gene_synonym="Bstk3; Camk1b; CaMKIbeta2; caMKlb1;
                     CaMKlb2; Punc"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1467..1472
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pnck"
                     /gene_synonym="Bstk3; Camk1b; CaMKIbeta2; caMKlb1;
                     CaMKlb2; Punc"
                     /note="hexamer: AATAAA"
     polyA_site      1486
                     /gene="Pnck"
                     /gene_synonym="Bstk3; Camk1b; CaMKIbeta2; caMKlb1;
                     CaMKlb2; Punc"
                     /note="major polyA site"
ORIGIN      
        1 actgcgctag gagacattgc ggcggcggca gcggcggtgg cagcagctgc agacatgctg
       61 ctgctcaaga aacagacgga ggacatcagc agtgtctatg agatccggga gaagctgggc
      121 tcgggtgcct tctctgaggt gatgctggcc caggaaaggg gctctgctca tcttgtggcc
      181 ctcaagtgca ttcccaagaa agcacttcgg ggcaaggagg ccctggtgga gaatgagatc
      241 gcggtacttc gcagaatcag ccatcccaac attgtggctc tggaggacgt ccatgagagt
      301 ccttctcatc tctacttggc catggagctg gtaacaggtg gtgaactgtt tgaccgcatc
      361 atggagcggg gctcctacac agagaaggac gccagccacc ttgtagggca ggtccttggc
      421 gctgtctcct accttcatag cctgggcatc gtgcaccggg acctcaagcc tgaaaacctc
      481 ctctatgcca caccttttga ggactccaag atcatggtct ctgactttgg cctgtccaaa
      541 atacaagctg gcaacatgct aggcacagcc tgtgggaccc caggatatgt ggccccagag
      601 ctcctggagc agaaacccta cgggaaggcc gtagatgtgt gggccctggg tgtcatctcc
      661 tacatcctgc tgtgtgggta cccccccttc tatgatgaga gcgatcctga actcttcagc
      721 cagattctga gggccagcta tgagtttgac tccccctttt gggatgacat ctcagaatca
      781 gccaaagact tcattcgcca ccttctggaa cgtgatcccc agaagaggtt cacctgccag
      841 caggccctac agcatctttg gatctctggg gatgcagcct tcgataggga catcctgggt
      901 tctgtcagtg agcagatcca gaagaatttt gccaggaccc actggaagcg tgcattcaat
      961 gccacatcat tcctacgtca catccgtaag ctgggacaaa gcccagaggg tgaggaggcc
     1021 tccaggcagt gtatgacccg tcatagccac ccaggccttg ggactagcca gtcccccaag
     1081 tggtgaaaac caggtagatg ccaaggaagg ccaagtggac tgactcccgg tttttctttc
     1141 ctccagccct tttggtctct ttcctggatc cttgtcctcc agactggcct ctgctggaaa
     1201 gtctgagact gggtgtgatg catggcacta gggtacgggg cttccccagt atgtccccca
     1261 gcctctattc ttacctatgg tggaggctcc ctttcccatg tcgctgccac cctctatgga
     1321 aactgaggag gtgttcaaaa gtggacttgg gagccatcct tcctgcacct tgcacgaaca
     1381 catgcattgt gtggctgttc tgtgctttgc tgactgtggg tggtcctgct tgtgttgtgg
     1441 ccctttagtt cctccttttc ctaaccaata aagacaaaca gaaccatgaa aaaaaaaaaa
     1501 aaaaaa
//
