LOCUS       NM_001310605             797 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus polyamine-modulated factor 1 (Pmf1), transcript
            variant 2, mRNA.
ACCESSION   NM_001310605 XM_006501923
VERSION     NM_001310605.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 797)
  AUTHORS   Fededa,J.P., Esk,C., Mierzwa,B., Stanyte,R., Yuan,S., Zheng,H.,
            Ebnet,K., Yan,W., Knoblich,J.A. and Gerlich,D.W.
  TITLE     MicroRNA-34/449 controls mitotic spindle orientation during
            mammalian cortex development
  JOURNAL   EMBO J 35 (22), 2386-2398 (2016)
   PUBMED   27707753
REFERENCE   2  (bases 1 to 797)
  AUTHORS   Varma,D. and Salmon,E.D.
  TITLE     The KMN protein network--chief conductors of the kinetochore
            orchestra
  JOURNAL   J Cell Sci 125 (Pt 24), 5927-5936 (2012)
   PUBMED   23418356
  REMARK    Review article
REFERENCE   3  (bases 1 to 797)
  AUTHORS   Lampert,F. and Westermann,S.
  TITLE     A blueprint for kinetochores - new insights into the molecular
            mechanics of cell division
  JOURNAL   Nat Rev Mol Cell Biol 12 (7), 407-412 (2011)
   PUBMED   21633384
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 797)
  AUTHORS   Lopez-Garcia,C., Lopez-Contreras,A.J., Cremades,A., Castells,M.T.
            and Penafiel,R.
  TITLE     Transcriptomic analysis of polyamine-related genes and polyamine
            levels in placenta, yolk sac and fetus during the second half of
            mouse pregnancy
  JOURNAL   Placenta 30 (3), 241-249 (2009)
   PUBMED   19131104
REFERENCE   5  (bases 1 to 797)
  AUTHORS   Lopez-Garcia,C., Lopez-Contreras,A.J., Cremades,A., Castells,M.T.,
            Marin,F., Schreiber,F. and Penafiel,R.
  TITLE     Molecular and morphological changes in placenta and embryo
            development associated with the inhibition of polyamine synthesis
            during midpregnancy in mice
  JOURNAL   Endocrinology 149 (10), 5012-5023 (2008)
   PUBMED   18583422
REFERENCE   6  (bases 1 to 797)
  AUTHORS   Stephenson,A.H. and Seidel,E.R.
  TITLE     Analysis of the interactions of Nrf-2, PMF-1, and CSN-7 with the
            5'-flanking sequence of the mouse 4E-BP1 gene
  JOURNAL   Life Sci 79 (13), 1221-1227 (2006)
   PUBMED   16647090
  REMARK    GeneRIF: formation of the Nrf-2/PMF-1 complex is involved in
            transcriptional regulation of 4E-BP1
REFERENCE   7  (bases 1 to 797)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   8  (bases 1 to 797)
  AUTHORS   Wang,Y., Devereux,W., Woster,P.M. and Casero,R.A. Jr.
  TITLE     Cloning and characterization of the mouse polyamine-modulated
            factor-1 (mPMF-1) gene: an alternatively spliced homologue of the
            human transcription factor
  JOURNAL   Biochem J 359 (Pt 2), 387-392 (2001)
   PUBMED   11583586
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC102388.7.
            
            On Oct 6, 2022 this sequence version replaced NM_001310605.1.
            
            Transcript Variant: This variant (2) lacks two alternate in-frame
            exons in the coding region compared to variant 1. The encoded
            isoform (2) is shorter than isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF348509.1, SRR13422597.5737.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-168               AC102388.7         80599-80766
            169-364             AC102388.7         94822-95017
            365-797             AC102388.7         96352-96784
FEATURES             Location/Qualifiers
     source          1..797
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 38.82 cM"
     gene            1..797
                     /gene="Pmf1"
                     /gene_synonym="2600009M07Rik"
                     /note="polyamine-modulated factor 1"
                     /db_xref="GeneID:67037"
                     /db_xref="MGI:MGI:1914287"
     exon            1..168
                     /gene="Pmf1"
                     /gene_synonym="2600009M07Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             17..418
                     /gene="Pmf1"
                     /gene_synonym="2600009M07Rik"
                     /note="isoform 2 is encoded by transcript variant 2;
                     PMF-1"
                     /codon_start=1
                     /product="polyamine-modulated factor 1 isoform 2"
                     /protein_id="NP_001297534.1"
                     /db_xref="CCDS:CCDS79942.1"
                     /db_xref="GeneID:67037"
                     /db_xref="MGI:MGI:1914287"
                     /translation="MAEVSRDSEAAERGPEGSSPEAVPGDATIPRVKLLDAIVDTFLQ
                     KLVADRRRPSGIPEKDLCSVMAPYFLKQQDTLCHQVRKQEAKNQELADAVLAGRRQVE
                     ELQQQVRALQQTWQALHREQRELLSVLRAPE"
     exon            169..364
                     /gene="Pmf1"
                     /gene_synonym="2600009M07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            365..797
                     /gene="Pmf1"
                     /gene_synonym="2600009M07Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      772..777
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pmf1"
                     /gene_synonym="2600009M07Rik"
                     /note="hexamer: AATAAA"
     polyA_site      797
                     /gene="Pmf1"
                     /gene_synonym="2600009M07Rik"
                     /note="major polyA site"
ORIGIN      
        1 gcggttcaat ttcaacatgg ctgaggtgag ccgagatagc gaggctgcgg aaagggggcc
       61 tgagggctcc tctccggaag ctgtgccagg ggacgcgacc atccccaggg tgaaactcct
      121 ggacgccata gtagacactt tcctccagaa gctagtcgcc gacaggaggc gacccagtgg
      181 aatcccagag aaagacctgt gtagtgtcat ggcaccctac ttcctgaagc aacaggatac
      241 cctgtgtcat caagtacgga aacaggaagc caagaaccag gaactggccg acgctgtcct
      301 ggccgggcgc aggcaggtgg aggagctgca gcagcaggtt cgggccctcc agcaaacatg
      361 gcaggctcta cacagagagc agagggagct gctgtcagtg ctgagggcgc ctgagtgaac
      421 agctgctggg ctcagccctc tagagcgcct gtggaggcag tttccaggca gtaatggagt
      481 ccccaccacc gcttaggttc tgctggggtc acactgcctt cagattcctg ccgccatctt
      541 ctgcctgcag gattgggact cccaccctgg catcagacac caggctttgt cttctggagt
      601 tgcagccagc gctgccccat gcccttctga tcctccccct ctcccaccgc cctccctgga
      661 taggatttgg gcagggtttc agtctccact gattgccgcc ttgttctccc tgactgattg
      721 ctgccttgct ggctagccca agggccctgc catgttctcc ccacatccgt aaataaactt
      781 cctttcccac actgtca
//
