LOCUS       NM_011125               1806 bp    mRNA    linear   ROD 19-DEC-2022
DEFINITION  Mus musculus phospholipid transfer protein (Pltp), mRNA.
ACCESSION   NM_011125
VERSION     NM_011125.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1806)
  AUTHORS   Lebrun LJ, Pallot G, Nguyen M, Tavernier A, Dusuel A, Pilot T,
            Deckert V, Dugail I, Le Guern N, Pais De Barros JP, Benkhaled A,
            Choubley H, Lagrost L, Masson D, Gautier T and Grober J.
  TITLE     Increased Weight Gain and Insulin Resistance in HF-Fed PLTP
            Deficient Mice Is Related to Altered Inflammatory Response and
            Plasma Transport of Gut-Derived LPS
  JOURNAL   Int J Mol Sci 23 (21), 13226 (2022)
   PUBMED   36362012
  REMARK    GeneRIF: Increased Weight Gain and Insulin Resistance in HF-Fed
            PLTP Deficient Mice Is Related to Altered Inflammatory Response and
            Plasma Transport of Gut-Derived LPS.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1806)
  AUTHORS   Chen J, Qi H, Liu L, Niu Y, Yu S, Qin S and He L.
  TITLE     Elevated cholesteryl ester transfer and phospholipid transfer
            proteins aggravated psoriasis in imiquimod-induced mouse models
  JOURNAL   Lipids Health Dis 21 (1), 75 (2022)
   PUBMED   35982498
  REMARK    GeneRIF: Elevated cholesteryl ester transfer and phospholipid
            transfer proteins aggravated psoriasis in imiquimod-induced mouse
            models.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1806)
  AUTHORS   Nguyen M, Pallot G, Jalil A, Tavernier A, Dusuel A, Le Guern N,
            Lagrost L, Pais de Barros JP, Choubley H, Bergas V, Guinot PG,
            Masson D, Bouhemad B and Gautier T.
  TITLE     Intra-Abdominal Lipopolysaccharide Clearance and Inactivation in
            Peritonitis: Key Roles for Lipoproteins and the Phospholipid
            Transfer Protein
  JOURNAL   Front Immunol 12, 622935 (2021)
   PUBMED   34054798
  REMARK    GeneRIF: Intra-Abdominal Lipopolysaccharide Clearance and
            Inactivation in Peritonitis: Key Roles for Lipoproteins and the
            Phospholipid Transfer Protein.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1806)
  AUTHORS   Zhang K, Zheng J, Chen Y, Dong J, Li Z, Chiang YP, He M, Huang Q,
            Tang H and Jiang XC.
  TITLE     Inducible phospholipid transfer protein deficiency ameliorates
            atherosclerosis
  JOURNAL   Atherosclerosis 324, 9-17 (2021)
   PUBMED   33798923
  REMARK    GeneRIF: Inducible phospholipid transfer protein deficiency
            ameliorates atherosclerosis.
REFERENCE   5  (bases 1 to 1806)
  AUTHORS   Dusuel A, Deckert V, Pais de Barros JP, van Dongen K, Choubley H,
            Charron E, Le Guern N, Labbe J, Mandard S, Grober J, Lagrost L and
            Gautier T.
  TITLE     Human cholesteryl ester transfer protein lacks lipopolysaccharide
            transfer activity, but worsens inflammation and sepsis outcomes in
            mice
  JOURNAL   J Lipid Res 62, 100011 (2021)
   PUBMED   33500240
REFERENCE   6  (bases 1 to 1806)
  AUTHORS   Tu AY, Chen H, Johnson KA, Paigen B and Albers JJ.
  TITLE     Characterization of the mouse gene encoding phospholipid transfer
            protein
  JOURNAL   Gene 188 (1), 115-118 (1997)
   PUBMED   9099868
REFERENCE   7  (bases 1 to 1806)
  AUTHORS   LeBoeuf RC, Caldwell M, Tu A and Albers JJ.
  TITLE     Phospholipid transfer protein maps to distal mouse chromosome 2
  JOURNAL   Genomics 34 (2), 259-260 (1996)
   PUBMED   8661063
REFERENCE   8  (bases 1 to 1806)
  AUTHORS   Geijtenbeek TB, Smith AJ, Borst P and Wirtz KW.
  TITLE     cDNA cloning and tissue-specific expression of the
            phosphatidylcholine transfer protein gene
  JOURNAL   Biochem J 316 (Pt 1) (Pt 1), 49-55 (1996)
   PUBMED   8645232
REFERENCE   9  (bases 1 to 1806)
  AUTHORS   Albers JJ, Wolfbauer G, Cheung MC, Day JR, Ching AF, Lok S and Tu
            AY.
  TITLE     Functional expression of human and mouse plasma phospholipid
            transfer protein: effect of recombinant and plasma PLTP on HDL
            subspecies
  JOURNAL   Biochim Biophys Acta 1258 (1), 27-34 (1995)
   PUBMED   7654777
REFERENCE   10 (bases 1 to 1806)
  AUTHORS   Jiang XC and Bruce C.
  TITLE     Regulation of murine plasma phospholipid transfer protein activity
            and mRNA levels by lipopolysaccharide and high cholesterol diet
  JOURNAL   J Biol Chem 270 (29), 17133-17138 (1995)
   PUBMED   7615508
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK148330.1, AK149730.1 and U37226.1.
            
            [WARNING] On May 5, 2023 this sequence was replaced by NM_011125.3.
            
            On Dec 29, 2005 this sequence version replaced NM_011125.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U37226.1, AK148330.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-645               AK148330.1         6-650
            646-1267            AK149730.1         577-1198
            1268-1782           AK148330.1         1273-1787
            1783-1806           U37226.1           1713-1736
FEATURES             Location/Qualifiers
     source          1..1806
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 85.27 cM"
     gene            1..1806
                     /gene="Pltp"
                     /gene_synonym="Bpife; OD107"
                     /note="phospholipid transfer protein"
                     /db_xref="GeneID:18830"
                     /db_xref="MGI:MGI:103151"
     exon            1..125
                     /gene="Pltp"
                     /gene_synonym="Bpife; OD107"
                     /inference="alignment:Splign:2.1.0"
     exon            126..236
                     /gene="Pltp"
                     /gene_synonym="Bpife; OD107"
                     /inference="alignment:Splign:2.1.0"
     CDS             137..1618
                     /gene="Pltp"
                     /gene_synonym="Bpife; OD107"
                     /note="lipid transfer protein II"
                     /codon_start=1
                     /product="phospholipid transfer protein precursor"
                     /protein_id="NP_035255.1"
                     /db_xref="CCDS:CCDS17063.1"
                     /db_xref="GeneID:18830"
                     /db_xref="MGI:MGI:103151"
                     /translation="MVLLWALFLALLAGAHAELPGCKIRVTSAALDLVKQEGLRFLEQ
                     ELETITIPDVYGAKGHFYYNISDVRVTQLHLISSELHFQPDQDLLLNISNASLGLHFR
                     RQLLYWFLYDGGYINASAEGVSIRTGLQLSQDSSGRIKVSNVSCEASVSKMNMAFGGT
                     FRRMYNFFSTFITSGMRFLLNQQICPVLYHAGTVLLNSLLDTVPVRSSVDDLVGIDYS
                     LLKDPVVSNGNLDMEFRGAFFPLKEDNWSLPNRAVEPQLEDDERMVYVAFSEFFFDSA
                     MESYFQAGALQLTLVGDKVPSDLDMLLRATYFGSIVLLSPTVINSPLKLKLEATSPPR
                     CTIKPSGTTISITASVTITLAPPMLPEVELSKMIMEGRLSAKLTLRGKALRVKLDLRR
                     FQIYSNQSALESLALIPLQAPLKTLLQIGVMPLLNERTWRGVQIPLPEGINFVREVVT
                     NHAGFVTVGADLHFAKGLREVIDKNRPADVAASHVPPPSAAAA"
     exon            237..336
                     /gene="Pltp"
                     /gene_synonym="Bpife; OD107"
                     /inference="alignment:Splign:2.1.0"
     exon            337..465
                     /gene="Pltp"
                     /gene_synonym="Bpife; OD107"
                     /inference="alignment:Splign:2.1.0"
     exon            466..621
                     /gene="Pltp"
                     /gene_synonym="Bpife; OD107"
                     /inference="alignment:Splign:2.1.0"
     exon            622..685
                     /gene="Pltp"
                     /gene_synonym="Bpife; OD107"
                     /inference="alignment:Splign:2.1.0"
     exon            686..749
                     /gene="Pltp"
                     /gene_synonym="Bpife; OD107"
                     /inference="alignment:Splign:2.1.0"
     exon            750..841
                     /gene="Pltp"
                     /gene_synonym="Bpife; OD107"
                     /inference="alignment:Splign:2.1.0"
     exon            842..1018
                     /gene="Pltp"
                     /gene_synonym="Bpife; OD107"
                     /inference="alignment:Splign:2.1.0"
     exon            1019..1078
                     /gene="Pltp"
                     /gene_synonym="Bpife; OD107"
                     /inference="alignment:Splign:2.1.0"
     exon            1079..1243
                     /gene="Pltp"
                     /gene_synonym="Bpife; OD107"
                     /inference="alignment:Splign:2.1.0"
     exon            1244..1311
                     /gene="Pltp"
                     /gene_synonym="Bpife; OD107"
                     /inference="alignment:Splign:2.1.0"
     exon            1312..1354
                     /gene="Pltp"
                     /gene_synonym="Bpife; OD107"
                     /inference="alignment:Splign:2.1.0"
     exon            1355..1418
                     /gene="Pltp"
                     /gene_synonym="Bpife; OD107"
                     /inference="alignment:Splign:2.1.0"
     exon            1419..1495
                     /gene="Pltp"
                     /gene_synonym="Bpife; OD107"
                     /inference="alignment:Splign:2.1.0"
     exon            1496..1806
                     /gene="Pltp"
                     /gene_synonym="Bpife; OD107"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaaccgcggc gaggaggggg gtcggaggcc cagacttata aaggctgctg gacccgcgct
       61 acccgccaga ccccgccgcc cggatccccc gcgctgcctg tcgccccacg tgaccacact
      121 actaagcttg gtcgccatgg tcctgctctg ggccctcttc ctagcgctcc tggcaggtgc
      181 ccacgccgag ctcccgggct gcaagatccg cgtcacctcc gcggctctgg atctggtgaa
      241 gcaggaaggc ctgcgctttc tggaacaaga gctggagacc atcaccatcc cagacgtgta
      301 cggcgcaaag ggccactttt actacaatat ctcggacgtg agggtcacac agctgcacct
      361 gatatcctcg gaactccact tccagccaga ccaagatctg ctgctgaaca tctccaacgc
      421 atccttgggg ctgcacttcc ggaggcagct actctactgg ttcttatatg atgggggcta
      481 catcaatgcc tcggcggagg gtgtgtccat ccgaacaggt ctacagctct cccaggattc
      541 cagtggtcgg attaaagtgt ccaatgtctc ctgcgaggcc tctgtgtcta aaatgaatat
      601 ggccttcggg ggaaccttca ggaggatgta taactttttc tccacgttca tcacttctgg
      661 gatgcggttc ctcctcaacc agcagatctg ccctgtgctc taccatgctg ggacggtgtt
      721 gctcaactcc ctcctggaca cagtgcccgt gcgcagttct gtggatgatc tcgtgggcat
      781 cgattactcc cttctgaagg atcctgtggt ctccaacggc aacctggata tggaattccg
      841 gggagcattc ttccctctga aggaggacaa ctggagcctc cccaacaggg cggtggagcc
      901 tcagctggag gacgacgaga ggatggtgta cgtggccttt tccgagttct tctttgactc
      961 tgccatggag agctacttcc aggctggagc gctgcagctg acacttgttg gggacaaggt
     1021 gccgagtgac ctggacatgc ttctgagggc cacctacttt gggagcattg ttctcctgag
     1081 tccgacagtg attaactccc cactgaagct gaagctagag gccacgagcc ctccacgttg
     1141 taccatcaag ccgtcaggca ccaccatctc catcaccgcc agcgtcacca tcaccttggc
     1201 cccgcccatg ttgcccgaag tggagctgtc caagatgatc atggaaggcc gtctcagtgc
     1261 taagttgaca ctccggggca aggcgctgcg agtgaagctg gaccttcgaa ggtttcaaat
     1321 ctactcaaat cagtctgcgc tggagtctct ggcgctgatc ccactgcagg ccccactgaa
     1381 gacactgctg caaatcggag tgatgccttt gctgaacgag cgtacctggc gtggggtgca
     1441 gatccccctt cctgagggta tcaacttcgt gcgtgaggtg gtgaccaacc acgcgggctt
     1501 cgtcactgtt ggggctgacc tccactttgc caaagggctt cgagaagtga ttgacaagaa
     1561 ccgtcctgca gacgttgcgg cctcccatgt ccccccaccc tctgctgcag ctgcctgagc
     1621 ccatcacccc acctgggtgg ctggcattca ggaacctaac tgaagtcttc tctgcacccc
     1681 ctgccaaccc cttcccatct acagtgttag tggtcccggt gccacagaga agagcccagt
     1741 tggaagctat acccgattta attccagaat tagtcaacca tcaattagaa tccatccacc
     1801 cccctc
//
