LOCUS       NM_026385               1889 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus plasma membrane proteolipid (Pllp), mRNA.
ACCESSION   NM_026385
VERSION     NM_026385.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1889)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1889)
  AUTHORS   Rodriguez-Fraticelli,A.E., Bagwell,J., Bosch-Fortea,M.,
            Boncompain,G., Reglero-Real,N., Garcia-Leon,M.J., Andres,G.,
            Toribio,M.L., Alonso,M.A., Millan,J., Perez,F., Bagnat,M. and
            Martin-Belmonte,F.
  TITLE     Developmental regulation of apical endocytosis controls epithelial
            patterning in vertebrate tubular organs
  JOURNAL   Nat Cell Biol 17 (3), 241-250 (2015)
   PUBMED   25706235
  REMARK    GeneRIF: PLLP recruits the clathrin adaptor EpsinR to sort the
            SNARE machinery of the endolysosomal pathway into the subapical
            compartment, which is a switch for polarized endocytosis.
REFERENCE   3  (bases 1 to 1889)
  AUTHORS   Miller,A.D., Bergholz,U., Ziegler,M. and Stocking,C.
  TITLE     Identification of the myelin protein plasmolipin as the cell entry
            receptor for Mus caroli endogenous retrovirus
  JOURNAL   J Virol 82 (14), 6862-6868 (2008)
   PUBMED   18463156
  REMARK    GeneRIF: mouse PLLP also functioned well as a receptor for McERV
            but was simply not expressed in the mouse cell types that we
            originally tested.
REFERENCE   4  (bases 1 to 1889)
  AUTHORS   Hamacher,M., Pippirs,U., Kohler,A., Muller,H.W. and Bosse,F.
  TITLE     Plasmolipin: genomic structure, chromosomal localization, protein
            expression pattern, and putative association with Bardet-Biedl
            syndrome
  JOURNAL   Mamm Genome 12 (12), 933-937 (2001)
   PUBMED   11707781
REFERENCE   5  (bases 1 to 1889)
  AUTHORS   Moshier,J.A., Deutch,A.H. and Huang,R.C.
  TITLE     Structure and in vitro transcription of a mouse B1 cluster
            containing a unique B1 dimer
  JOURNAL   Gene 58 (1), 19-27 (1987)
   PUBMED   3692173
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK002477.1.
            
            On Apr 6, 2007 this sequence version replaced NM_026385.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK002477.1, BC024534.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1889              AK002477.1         2-1890
FEATURES             Location/Qualifiers
     source          1..1889
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 46.66 cM"
     gene            1..1889
                     /gene="Pllp"
                     /gene_synonym="0610010I06Rik; Plapi; Tm4sf11"
                     /note="plasma membrane proteolipid"
                     /db_xref="GeneID:67801"
                     /db_xref="MGI:MGI:1915051"
     exon            1..207
                     /gene="Pllp"
                     /gene_synonym="0610010I06Rik; Plapi; Tm4sf11"
                     /inference="alignment:Splign:2.1.0"
     CDS             73..621
                     /gene="Pllp"
                     /gene_synonym="0610010I06Rik; Plapi; Tm4sf11"
                     /note="transmembrane 4 superfamily member 11"
                     /codon_start=1
                     /product="plasmolipin"
                     /protein_id="NP_080661.1"
                     /db_xref="CCDS:CCDS22546.1"
                     /db_xref="GeneID:67801"
                     /db_xref="MGI:MGI:1915051"
                     /translation="MAEFPSKVSTRTSSPAQGVGASVSALRPDLGFVRSALGVLALLQ
                     LALGLLVWALIADTPYHLYPAYGWVMFVAVFLWLVTIVFFIIYLFQLHMKLYMVPWPL
                     VLLIFFVAATVLYITAFIACAAAVDLTSLRGSRPYNQRSAASFFACLVMIAYGVSAFF
                     SFQAWRGVGSNAATSQMAGGYS"
     exon            208..381
                     /gene="Pllp"
                     /gene_synonym="0610010I06Rik; Plapi; Tm4sf11"
                     /inference="alignment:Splign:2.1.0"
     exon            382..504
                     /gene="Pllp"
                     /gene_synonym="0610010I06Rik; Plapi; Tm4sf11"
                     /inference="alignment:Splign:2.1.0"
     exon            505..1889
                     /gene="Pllp"
                     /gene_synonym="0610010I06Rik; Plapi; Tm4sf11"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1316..1321
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pllp"
                     /gene_synonym="0610010I06Rik; Plapi; Tm4sf11"
                     /note="hexamer: AATAAA"
     polyA_site      1343
                     /gene="Pllp"
                     /gene_synonym="0610010I06Rik; Plapi; Tm4sf11"
                     /note="major polyA site"
     regulatory      1870..1875
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pllp"
                     /gene_synonym="0610010I06Rik; Plapi; Tm4sf11"
                     /note="hexamer: ATTAAA"
     polyA_site      1889
                     /gene="Pllp"
                     /gene_synonym="0610010I06Rik; Plapi; Tm4sf11"
ORIGIN      
        1 agccggagcc gcagtcgcag ccccggagca gcgccgggag cgcggccaga gcgtcgtagg
       61 ctcgcgatcg ctatggcgga gttcccgtcg aaagtgagca cgaggaccag cagccccgcg
      121 cagggcgtgg gagcctctgt gtctgcgctg cgaccggatc tgggcttcgt gcgctccgct
      181 cttggggtgc tcgcgcttct gcagctggca ctggggctgc tggtgtgggc cctgattgct
      241 gacaccccat accatctgta tcctgcctat ggctgggtca tgtttgtcgc tgtcttcctc
      301 tggctggtga caatcgtctt cttcatcatc tacctgtttc aactgcacat gaagttgtac
      361 atggtgccct ggccgttggt gttactgatc ttttttgtcg ctgccacggt tctctacatt
      421 actgccttta tcgcctgtgc agcggcggtc gatctgacat ccctgagggg ctcccggcca
      481 tataaccagc gctcagctgc ctctttcttt gcttgtctgg tgatgattgc ctacggagtg
      541 agcgctttct tcagcttcca ggcctggcga ggagtgggta gcaacgcggc cacgagtcag
      601 atggctgggg gctactccta agccagctat gctgtggcct gagccatggc tgggtcttag
      661 cacagggtca ccccctaagc ttactggact caaactctcc agcactcctg aggaactggc
      721 ctacactggc acagatggaa ctggccaaga gccaggggtg gggacatcct ccccacctcc
      781 cttattcagc agaaggtgat ggggtttggg gagctctgcc ttgtcatcag agaacttcag
      841 tagcccaggc tgggccaccc tgttcaccag cactaaatgc actaacagac cctcagcctc
      901 tgacctgcct cagtataacc ctaacaaaag acagattatc tttgtcccca agccaagtaa
      961 gccccgggct cttctggtcc caccgtcccc tcccctgccc catgccaacc tgtcacctgt
     1021 agagagactt ttataggaag agttgggatt tctgggactg gacgatttct gataactgtt
     1081 ggttacaaca gtttccgatg gcagcaagct cgctaggtcc cctccctcat gtggaactct
     1141 cccctttggg agagctagca cccgtgcaag ggttctcccc gccccccccg ccccaggctg
     1201 ctgattaggc acaggggact tccaaggagg gacagaagga agcagggcct tgcctggtga
     1261 gctgtcatgg ggttaatggt gactcttgtt tggaattatt attttttaca atttaaataa
     1321 aaatggaagc atctgtttgg aaaggggtta tcattcctgg tcttagatgt ttgctaaggt
     1381 ttttactttt tggtcctttt agaagatggc aacaattaag atgaaattag aatcagatac
     1441 ttgtgttttg atactgttag agggaggaga tcaagttttg gctcttggtc cccgctcaca
     1501 cttgtcttgg tgattgtcaa tatacatagt gtccactttg gaggttaggt aatgaagtct
     1561 ccctgttcca ggaggactag cccattttga ggcatagagg aaagcgaatc ctaggaagcc
     1621 agagctctca gagacccatc aggtatctca cggcctgacg taatgcctcg tacaatctca
     1681 gaatgccggt ttaggggagg cattctgggt tctgctgctc aggcagggaa tagaaggcag
     1741 catctcagtg atgggtcaca cgggccagac tcttaacttt cttgcccttg tcttgtccat
     1801 tggaggacgc acatagcatc tgtccaagtt tgtggaccaa cacacaaaat tagcaagctt
     1861 acatagaata ttaaactgtt cttgcagtc
//
