LOCUS       NM_183034               6003 bp    mRNA    linear   ROD 19-NOV-2024
DEFINITION  Mus musculus pleckstrin homology domain containing, family M (with
            RUN domain) member 1 (Plekhm1), mRNA.
ACCESSION   NM_183034
VERSION     NM_183034.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6003)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6003)
  AUTHORS   Zhao,Y., Zheng,D. and Cvekl,A.
  TITLE     A comprehensive spatial-temporal transcriptomic analysis of
            differentiating nascent mouse lens epithelial and fiber cells
  JOURNAL   Exp Eye Res 175, 56-72 (2018)
   PUBMED   29883638
REFERENCE   3  (bases 1 to 6003)
  AUTHORS   Fujiwara,T., Ye,S., Castro-Gomes,T., Winchell,C.G., Andrews,N.W.,
            Voth,D.E., Varughese,K.I., Mackintosh,S.G., Feng,Y., Pavlos,N.,
            Nakamura,T., Manolagas,S.C. and Zhao,H.
  TITLE     PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone
            homeostasis
  JOURNAL   JCI Insight 1 (17), e86330 (2016)
   PUBMED   27777970
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6003)
  AUTHORS   Witwicka,H., Jia,H., Kutikov,A., Reyes-Gutierrez,P., Li,X. and
            Odgren,P.R.
  TITLE     TRAFD1 (FLN29) Interacts with Plekhm1 and Regulates Osteoclast
            Acidification and Resorption
  JOURNAL   PLoS One 10 (5), e0127537 (2015)
   PUBMED   25992615
  REMARK    GeneRIF: TRAFD1, in association with Plekhm1/Rab7-positive late
            endosomes-early lysosomes, has a previously unknown role in vesicle
            trafficking, acidification, and resorption in osteoclasts
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6003)
  AUTHORS   McEwan,D.G. and Dikic,I.
  TITLE     PLEKHM1: Adapting to life at the lysosome
  JOURNAL   Autophagy 11 (4), 720-722 (2015)
   PUBMED   25905573
  REMARK    GeneRIF: identified PLEKHM1 as an endolysosomal adaptor platform
            that acts as a central hub to integrate endocytic and autophagic
            pathways at the lysosome
REFERENCE   6  (bases 1 to 6003)
  AUTHORS   McEwan,D.G., Popovic,D., Gubas,A., Terawaki,S., Suzuki,H.,
            Stadel,D., Coxon,F.P., Miranda de Stegmann,D., Bhogaraju,S.,
            Maddi,K., Kirchof,A., Gatti,E., Helfrich,M.H., Wakatsuki,S.,
            Behrends,C., Pierre,P. and Dikic,I.
  TITLE     PLEKHM1 regulates autophagosome-lysosome fusion through HOPS
            complex and LC3/GABARAP proteins
  JOURNAL   Mol Cell 57 (1), 39-54 (2015)
   PUBMED   25498145
REFERENCE   7  (bases 1 to 6003)
  AUTHORS   Brommage,R., Liu,J., Hansen,G.M., Kirkpatrick,L.L., Potter,D.G.,
            Sands,A.T., Zambrowicz,B., Powell,D.R. and Vogel,P.
  TITLE     High-throughput screening of mouse gene knockouts identifies
            established and novel skeletal phenotypes
  JOURNAL   Bone Res 2, 14034 (2014)
   PUBMED   26273529
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 6003)
  AUTHORS   Ye,S., Fowler,T.W., Pavlos,N.J., Ng,P.Y., Liang,K., Feng,Y.,
            Zheng,M., Kurten,R., Manolagas,S.C. and Zhao,H.
  TITLE     LIS1 regulates osteoclast formation and function through its
            interactions with dynein/dynactin and Plekhm1
  JOURNAL   PLoS One 6 (11), e27285 (2011)
   PUBMED   22073305
  REMARK    GeneRIF: results indicate that LIS1 is a previously unrecognized
            regulator of osteoclast formation, microtubule organization, and
            lysosomal secretion by virtue of its ability to modulate dynein
            function and Plekhm1
REFERENCE   9  (bases 1 to 6003)
  AUTHORS   Nishimura,M., Yokoi,N., Miki,T., Horikawa,Y., Yoshioka,H.,
            Takeda,J., Ohara,O. and Seino,S.
  TITLE     Construction of a multi-functional cDNA library specific for mouse
            pancreatic islets and its application to microarray
  JOURNAL   DNA Res 11 (5), 315-323 (2004)
   PUBMED   15747579
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY203268.1, BC053079.1, AK048562.1, AL772325.4 and BP767414.1.
            
            On Jul 6, 2018 this sequence version replaced NM_183034.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC053079.1, AK155357.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-41                BY203268.1         11-51
            42-5169             BC053079.1         1-5128
            5170-5390           AK048562.1         1787-2007
            5391-5394           AL772325.4         8945-8948           c
            5395-5536           AK048562.1         2008-2149
            5537-6003           BP767414.1         22-488              c
FEATURES             Location/Qualifiers
     source          1..6003
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 67.09 cM"
     gene            1..6003
                     /gene="Plekhm1"
                     /gene_synonym="AP162; B2; D330036J23Rik"
                     /note="pleckstrin homology domain containing, family M
                     (with RUN domain) member 1"
                     /db_xref="GeneID:353047"
                     /db_xref="MGI:MGI:2443207"
     exon            1..113
                     /gene="Plekhm1"
                     /gene_synonym="AP162; B2; D330036J23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            114..199
                     /gene="Plekhm1"
                     /gene_synonym="AP162; B2; D330036J23Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             155..3379
                     /gene="Plekhm1"
                     /gene_synonym="AP162; B2; D330036J23Rik"
                     /note="PH domain-containing family M member 1"
                     /codon_start=1
                     /product="pleckstrin homology domain-containing family M
                     member 1"
                     /protein_id="NP_898855.1"
                     /db_xref="CCDS:CCDS25518.1"
                     /db_xref="GeneID:353047"
                     /db_xref="MGI:MGI:2443207"
                     /translation="MLSVENGLDPRAAIQVIKKKLVGSVKALQKQHVSLDTVVTSEDG
                     DANTMCSALEAVFIHGLHAKHIRAEAGGKRKKHTHQKALPQPVFWPLLKAITHRHIVS
                     DLEHLVFINTDVGRCRAWLRLALNDGLMECYLKLLLQEPARLCEYYQPTALLRDAEEA
                     EFLLSFLQGLTSLSFELSYKSAILNEWTLTPLSLSGLCPLSELDPLTTSGAELQRKES
                     LDSISHSSGSEDIEVQHSGHKIRRNRKLTASSLSLDTASSSQLSCSLNSDSCLLQENG
                     PKSPDHSEEPMSYDSDLGMANTDDPDRSLQEVLSEFSKAQVNSAPSSGPNQEPDTPMF
                     QTPLSLHSLATSTHLHFEGSEELFPAHKSSGTSSGGHKHQLLPQETPDEKQLGTAQAG
                     PAQSTSDQQPSSPVGGAAGQGSGPWKALEYGRVGPKLVVSSPTSPKGKSWISEDDFCR
                     PPQEPALKSAAGLCTSPVQDTPESRAALHGPFSQGPRKSCSLGALDKACVPSQACGNA
                     QPAPAPAPAPAPAPAPAPGVTQDHKNFCVVHRRQMGLSNPFRGLMKLGTVARRGAMGI
                     WKEFFCELSPLEFRLYLSDEERTCVESCSLLRCEAVGPAHSDGRFELVFSGKKLALRA
                     SSQDEAEDWLDRVREALQKVRPQQEDEWVNIQYPDQAEDAPEAPPDSLPPYSTLLPEP
                     AGAQGMQLDWTSAQVPEPDAIKESLLYLYADRTWVPYIFSLSLESLKCFRVRNNEKML
                     SDSHGVETIRDILPDTSLGGPAFFKIITAKAVLKLQAKNTEEATHWRDLVRKVLASYL
                     ESAEEAVTLGGSLDEKCQEVLKFATRENGFLLQYLVAIPTEKGLDSQGCFCAGCSRQI
                     GFSFVRPKLCAFSGLYYCDFCHQDDASVIPARIIHNWDLTKRPVCRQALKFLAQIRAQ
                     PLINLQLVNASLYEHVERMHLIGRSREQLKLLGDYLGLCRSGALKELCKRLSHRNYLL
                     ESPHRFSVADLQQIAEGVYEGFLKALIEFASQHVYHCDLCTQRGFICQICHHQDIIFP
                     FEFDTTVRCAECRTVFHQSCQAVVRKGCPRCARRRKYQEQNVVS"
     exon            200..447
                     /gene="Plekhm1"
                     /gene_synonym="AP162; B2; D330036J23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            448..1074
                     /gene="Plekhm1"
                     /gene_synonym="AP162; B2; D330036J23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1075..1465
                     /gene="Plekhm1"
                     /gene_synonym="AP162; B2; D330036J23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1466..1784
                     /gene="Plekhm1"
                     /gene_synonym="AP162; B2; D330036J23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1785..2705
                     /gene="Plekhm1"
                     /gene_synonym="AP162; B2; D330036J23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2706..2851
                     /gene="Plekhm1"
                     /gene_synonym="AP162; B2; D330036J23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2852..3045
                     /gene="Plekhm1"
                     /gene_synonym="AP162; B2; D330036J23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3046..3109
                     /gene="Plekhm1"
                     /gene_synonym="AP162; B2; D330036J23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3110..3267
                     /gene="Plekhm1"
                     /gene_synonym="AP162; B2; D330036J23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3268..5986
                     /gene="Plekhm1"
                     /gene_synonym="AP162; B2; D330036J23Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5148..5153
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Plekhm1"
                     /gene_synonym="AP162; B2; D330036J23Rik"
                     /note="hexamer: AGTAAA"
     polyA_site      5172
                     /gene="Plekhm1"
                     /gene_synonym="AP162; B2; D330036J23Rik"
                     /note="major polyA site"
     regulatory      5965..5970
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Plekhm1"
                     /gene_synonym="AP162; B2; D330036J23Rik"
                     /note="hexamer: AATAAA"
     polyA_site      5986
                     /gene="Plekhm1"
                     /gene_synonym="AP162; B2; D330036J23Rik"
ORIGIN      
        1 agacgccgcg cgccgcttcc tgttgtcagt gcctttggag ccgcagcttc tgctcggaac
       61 cgaggggggt ctcgcttcgc ccggagcgcc gccacctgct cctgatccct tcggtgtcat
      121 gtgagtctcc ctcagagctg ctgcccgagt ggaaatgctc tcagtggaga atggcctgga
      181 ccctcgtgct gccatccagg tcatcaagaa gaagctcgtg ggatccgtga aggctctgca
      241 gaaacagcat gtgtctctgg acacagtggt caccagtgaa gatggagatg ccaacaccat
      301 gtgcagtgcc ctggaggctg tgttcatcca cggcctgcat gccaagcaca tccgcgccga
      361 ggctggcggc aaaaggaaga agcacactca ccagaaggct ctgcctcagc ctgtcttctg
      421 gccccttctg aaagccatca cccacagaca cattgtctca gatttggagc acctggtctt
      481 catcaacaca gatgtaggcc gttgccgagc ctggctgcgg ttggccctca atgacggtct
      541 gatggagtgc tatctgaaac tgctcctgca ggaacctgca cggttgtgcg agtactatca
      601 gcccacagcc ctgcttcgag atgccgagga ggctgagttc ctcctgagct tcctgcaagg
      661 actaacatcc ttgtccttcg aactctccta caagtcagcc atcttaaatg aatggacact
      721 caccccattg tcgctctctg ggctttgccc cctctctgaa ctcgaccctc tcactacctc
      781 tggtgcagaa ctacagcgga aagagtctct ggattcaatt tcccattcct cgggctctga
      841 ggacatcgaa gtccaacact caggccataa gatccgcagg aacaggaagc tcactgcctc
      901 ttccctcagc ctggacacag ccagttcatc ccagctgtcc tgcagcctaa attctgacag
      961 ctgcctgctc caagagaatg gtcccaagag tccagaccat tctgaggaac ccatgtccta
     1021 tgactcagat ctgggcatgg caaacaccga tgaccccgac aggtctctgc aagaggtgtt
     1081 gtcggaattc agcaaagccc aggtaaattc tgcaccaagc agcggaccaa accaagagcc
     1141 agacaccccc atgttccaga cgcccctctc cctccatagc ctagctacca gcacacacct
     1201 gcactttgag ggatctgaag agctctttcc tgcccacaaa tcctctggga catcaagtgg
     1261 tggccataag catcagctac tgccccagga gaccccagac gagaagcagc taggcactgc
     1321 ccaagctggc cctgcacaga gcacttcaga ccagcagcct tctagtcctg tgggtggagc
     1381 agctggccaa gggagtggcc cttggaaggc cctggagtat ggcagagtcg gaccgaagct
     1441 tgtggtttcc tctcctacga gtccgaaagg caagagctgg atttctgaag atgacttctg
     1501 ccgacctccc caggagcctg ctctaaagag cgctgcaggt ctctgcacat ctcctgtgca
     1561 agacactcca gagtcaaggg ctgctctcca cgggcctttt tctcaaggac caagaaagag
     1621 ctgttccttg ggggcattag acaaagcatg tgtgccctca caggcctgtg gaaatgccca
     1681 gccagctcca gccccagctc cagctccagc cccagcccca gccccagctc caggggtgac
     1741 acaagaccat aaaaacttct gtgtggtgca ccgaaggcaa atggggctgt ccaacccatt
     1801 ccggggcctc atgaagctgg gcacagtggc ccggcgagga gccatgggca tctggaagga
     1861 attcttttgt gagctgtccc cgttggagtt ccgcctctac ttgagtgatg aggaacgcac
     1921 ctgtgtggag agctgctccc tgctccgatg tgaggctgtg gggccagcac acagtgatgg
     1981 acgttttgag ttggtcttct cgggcaagaa gctggctctc cgtgcctcct cccaagacga
     2041 ggctgaggac tggcttgacc gcgtacggga ggctctgcag aaggtgcgcc ctcagcagga
     2101 agatgagtgg gtgaatatcc agtacccaga ccaggctgag gatgccccag aggctccacc
     2161 agacagcctc cccccctatt caactctact ccccgagcct gcgggtgccc agggcatgca
     2221 gttggactgg acatctgccc aggttccaga accagatgct atcaaagagt cccttttgta
     2281 tctgtatgca gaccggacct gggtccccta tatcttttcc ctgtccttgg agtctctgaa
     2341 atgtttccga gtgagaaaca atgagaagat gctaagtgat agccatggag tggagaccat
     2401 ccgagacatc ctgccagaca ccagccttgg gggcccagcc ttcttcaaaa tcatcacggc
     2461 caaggccgtc ctgaaactgc aggccaaaaa caccgaggag gccacccact ggagagacct
     2521 ggtccggaaa gtgctggcat cttacctaga gtcagctgag gaggctgtga cacttggtgg
     2581 gagtctggat gaaaaatgtc aggaggtgct gaagtttgct accagggaga acggcttcct
     2641 gctacagtac cttgtggcca tcccgaccga gaagggcctc gactcccagg gctgcttctg
     2701 cgcaggctgc tcccgacaga tcggcttctc ctttgtacga cccaagctct gtgccttctc
     2761 tggcctgtat tactgtgact tctgccacca agacgatgcc tcagtgattc cagccagaat
     2821 catccacaac tgggacctca cgaagcgccc ggtatgccgg caggccctga agttcctggc
     2881 ccagatccgg gcccaacctc tcatcaacct gcagctggtg aacgcctctc tgtatgagca
     2941 tgtggaacgc atgcacctca ttggcaggag ccgggagcag ctgaaacttc tgggggacta
     3001 cctgggcctg tgccgaagtg gtgctctgaa ggagttgtgc aaaaggctga gccacaggaa
     3061 ttatctcctg gagtctccac acagattcag tgttgctgac ctccagcaga ttgcagaggg
     3121 ggtatatgaa gggttcctca aagccctgat tgaattcgca tcccagcatg tctaccactg
     3181 tgacctgtgc acccagcgag gcttcatctg ccagatctgc caccaccagg acatcatctt
     3241 tccctttgag tttgacacca cagtcaggtg tgctgaatgc agaactgtct tccatcagag
     3301 ctgccaggct gtggtgagga agggctgtcc ccgatgtgcc cgccggcgca agtaccagga
     3361 acagaacgtt gtcagttaac cccgctgtcc caactttctg gggccatcca tctgggtctg
     3421 tcattggcct aggcttcctc ttctccctat aaggaagact ctcgggtgtg cccagagctc
     3481 cagcctaccg agaaggcgca ggaagtccca gtgatgcccg aggcccctca caacccttct
     3541 gctccaagag gggatccagc aggtgcctct gcccagggcc tggcttcccc ggctgtcatg
     3601 gctcctccgt tagggctgtt catgtgtaca ctgtgggaac gaagcctggt gagcattgcc
     3661 accatgctcc tgagtaaagg tctagttttt ttaaggcagg ttttttcccc cttcatagtt
     3721 aaacagaaaa tattttttta ttcttgacct acccaagtca cccaagaaat acaacccttc
     3781 gcccgaccag atgggtgaga gcagccccag cccaggcagg catggagctg ggtggacagg
     3841 cctctgctgg gttagcctat ctggactggg tgctttgcct ctgccctttc tggcacatac
     3901 tgccaagagt gcaagtgtca tgtgccaaat ggcctgtcat tgtgaggctg ggttctgtgg
     3961 ccacctttcc ctccactcct cacgttctca cctgtaaagc gtccctccct ctgttggagc
     4021 tcttggctta cctaatagct gtgagtacag cacagcagga gcagggggtg accagcacca
     4081 gcactgtcag cactttgagc cttccctgct caggaaggcc atgaccttgc ccacctcatc
     4141 cccatgcccc cttaccctgc agggtagagt aggctagaaa ccagagagct ccaagctcca
     4201 tctgtggaga ggtgccatcc ttgggctgca gagagaggag aatttgcccc aaagctgcct
     4261 gcagagcttc accaccctta gtctcacaaa gccttgagtt catagcattt cttgagtttt
     4321 caccctgccc agcaggacac tgcagcaccc aaagggcttc ccaggagtag ggttgccctc
     4381 aagaggctct tgggtctgat ggccacatcc tggaattgtt ttcaagttga tggtcacagc
     4441 cctgaggcat gtaggggcgt ggggatgcgc tctgctctgc tctcctctcc tgaacccctg
     4501 aaccctctgg ctaccccaga gcacttagag ccaggggcct caggtggaat ggagggtctc
     4561 cctggaaatg tgcctgtcct gtctagagga ggttacccca ccctccctga ggtgaatgag
     4621 ctgagtcacc tgaagcttga attgtgcaat aaaacatagg agtaggaagg cagatggcag
     4681 aggctgccaa gagttcatct gtccgtcatg gaagacagcg ctcaccagtg gttgaaacac
     4741 caaagccccc agaaccaccc agtgtatctc tatctgcacc cccgagctag cattaacacg
     4801 tcccccaaac tacaacctga tcagagcctc ctttccttgt tttgggatcc tgaatgggca
     4861 agagtctgtc ccctgtgggc ctgtcacatg agggtattcc agaacctgtc taggagatgg
     4921 agccctccca gtgtctgggc tgcgagcata agagctggcc ctgtccttga ctaagcgact
     4981 gactgactgc tcaagtgaga gacttgcccc caccagaaga gtgctcacgt gaacctcagc
     5041 agtgcccaca ctattggaaa aaatgctatt ttatgcaata ttctgacaag tgagccttgg
     5101 cagtgcagag gagaaactgc tgctgtgtgg tatttgagtg attttgcagt aaagagctgg
     5161 cctttctaag cagtcttgtt tctgaatctc aatcatttgg ctctggggaa acactacctg
     5221 gctcccctta gtcctatgca ctgagcattt cagggtccat ggagcacact tgcctgacca
     5281 agcagcgagg gagaagaggt aagtgaggga atgtaggctg cgggcgcagg tgggtgcctt
     5341 tctctctctc tctctctctc tctctctctc tctctctctc tctctctctc tctcaaacac
     5401 acacacacac acacaccctg taaaagcagg actctgggca tggagagagg caaacaagga
     5461 aaccgggccc tggcacctac actcacggat taaagactcc agaggcctgt ctactgctag
     5521 ccttccccag gagctccagg agaagccccc acccccacca aacaccccca ccccccactg
     5581 cccctgttag gacaaaagaa ggaaacagat taattcctag ggaaaccagg ttgcagaaaa
     5641 atgggacaga aaaagacaac atccagggct tcgtttcctg gccttgagcg ccctcagcca
     5701 gtgggtgggt gctccttggc catctttgag gcaggttctc agggctcaga gcaaagggag
     5761 aggaactgga tttggaggtt gggggtggca ggcccggggg aggcgcctgg cacttgcgct
     5821 gctgctgctg ctgtctttgg ttgtctttcc accttcagca cagtgcctct gagggcagtt
     5881 tcccctttcc cctgtctaga gggggatggg caaactggag ttctcatccc cagaaagtgc
     5941 ctcctataat gaaaggaaca ggttaataaa atacatgcgc tcaccaaaaa aaaaaaaaaa
     6001 aaa
//
