LOCUS       NM_023900                904 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus pleckstrin homology domain containing, family J member
            1 (Plekhj1), mRNA.
ACCESSION   NM_023900
VERSION     NM_023900.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 904)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 904)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   3  (bases 1 to 904)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   4  (bases 1 to 904)
  AUTHORS   Dresser,D.W., Jamin,S.P., Atkins,C.J. and Guerrier,D.
  TITLE     An expressed GNRP-like gene shares a bi-directional promoter with
            SF3A2 (SAP62) immediately upstream of AMH
  JOURNAL   Gene 277 (1-2), 163-173 (2001)
   PUBMED   11602354
REFERENCE   5  (bases 1 to 904)
  AUTHORS   Dresser,D.W., Hacker,A., Lovell-Badge,R. and Guerrier,D.
  TITLE     The genes for a spliceosome protein (SAP62) and the anti-Mullerian
            hormone (AMH) are contiguous
  JOURNAL   Hum Mol Genet 4 (9), 1613-1618 (1995)
   PUBMED   8541848
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC166937.2.
            
            On Jan 31, 2022 this sequence version replaced NM_023900.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC005565.1, CB181646.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164143 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-190               AC166937.2         86438-86627
            191-258             AC166937.2         86731-86798
            259-325             AC166937.2         86869-86935
            326-416             AC166937.2         87886-87976
            417-480             AC166937.2         88054-88117
            481-904             AC166937.2         88186-88609
FEATURES             Location/Qualifiers
     source          1..904
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 39.72 cM"
     gene            1..904
                     /gene="Plekhj1"
                     /gene_synonym="9530063M10Rik"
                     /note="pleckstrin homology domain containing, family J
                     member 1"
                     /db_xref="GeneID:78670"
                     /db_xref="MGI:MGI:1925920"
     exon            1..190
                     /gene="Plekhj1"
                     /gene_synonym="9530063M10Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             97..591
                     /gene="Plekhj1"
                     /gene_synonym="9530063M10Rik"
                     /note="guanine nucleotide releasing protein x; PH
                     domain-containing family J member 1"
                     /codon_start=1
                     /product="pleckstrin homology domain-containing family J
                     member 1"
                     /protein_id="NP_076389.2"
                     /db_xref="CCDS:CCDS48640.1"
                     /db_xref="GeneID:78670"
                     /db_xref="MGI:MGI:1925920"
                     /translation="MRYNEKELQALSRQPAEMAAELGMRGPKKGSVAKRRLVKLVVNF
                     LFYFRPDEAEPLGALLLERCRVAQEEPGGFSISFVEDLSRKYHFECCSQEQCQDWMEA
                     LQRASYEYMRQSLIFYRNEIRKMTGKDPLEQFGISEEARFQLNSLPKDGRTTCIGSQL
                     NVLD"
     exon            191..258
                     /gene="Plekhj1"
                     /gene_synonym="9530063M10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            259..325
                     /gene="Plekhj1"
                     /gene_synonym="9530063M10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            326..416
                     /gene="Plekhj1"
                     /gene_synonym="9530063M10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            417..480
                     /gene="Plekhj1"
                     /gene_synonym="9530063M10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            481..904
                     /gene="Plekhj1"
                     /gene_synonym="9530063M10Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      883..888
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Plekhj1"
                     /gene_synonym="9530063M10Rik"
                     /note="hexamer: AATAAA"
     polyA_site      904
                     /gene="Plekhj1"
                     /gene_synonym="9530063M10Rik"
                     /note="major polyA site"
ORIGIN      
        1 gctctctgag acttttgtgg cgctggctgc ggcttcgggg aggacggcgg ccgagaggca
       61 gggcgcgtgt tggttcgcgc ggatccgtgc ggcgggatgc ggtacaacga gaaagagttg
      121 caggcgctgt cccgacagcc ggcagagatg gcggccgagc tgggcatgcg gggccccaag
      181 aagggcagcg tggccaagcg gcgactggtg aagctggtgg tcaacttcct cttttacttc
      241 cgcccggacg aggccgagcc cctcggagcc ctgttgctgg agcgctgcag agtggcccag
      301 gaagaaccgg gcggcttctc catcagcttc gtcgaagacc tcagcaggaa atatcacttt
      361 gaatgctgta gccaagagca gtgtcaggac tggatggaag ctctgcagcg ggccagctac
      421 gaatacatgc gacagagcct catcttctac aggaatgaga tcaggaagat gactggcaag
      481 gaccccctgg agcagtttgg catctccgag gaggccaggt tccagctgaa tagcctgcct
      541 aaggatgggc ggactacttg tattggctcc cagttaaatg tgttggactg accctctctg
      601 ggcccctggc taccctggga agtttttttt tttttaatat aggttttaat acatctgttc
      661 aaaaggtcca gaggaggtgg gcagggtctg tggtcctcgt tctccatgcc atctccctgc
      721 cagcacccct tgagtgtcca catccaggga ccgagcctgg cacagctccc ctatccattg
      781 ccagatgaat gtataatgct agatgaagct gtgaaccccc cccccccctc ctgctgatag
      841 agcagggcat gggtgctggc ctcagtgctc agcctgctct ttaataaagg tacctctttt
      901 ctga
//
