LOCUS       NM_001346769            3068 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus pleckstrin homology domain containing, family H (with
            MyTH4 domain) member 3 (Plekhh3), transcript variant 2, mRNA.
ACCESSION   NM_001346769 XM_006533034
VERSION     NM_001346769.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3068)
  AUTHORS   Watahiki,A., Waki,K., Hayatsu,N., Shiraki,T., Kondo,S.,
            Nakamura,M., Sasaki,D., Arakawa,T., Kawai,J., Harbers,M.,
            Hayashizaki,Y. and Carninci,P.
  TITLE     Libraries enriched for alternatively spliced exons reveal splicing
            patterns in melanocytes and melanomas
  JOURNAL   Nat Methods 1 (3), 233-239 (2004)
   PUBMED   15782199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL590969.12, AK164128.1 and BE332650.1.
            
            On Oct 30, 2016 this sequence version replaced XM_006533034.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK154510.1, AK164128.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-55                AL590969.12        218154-218208
            56-889              AK164128.1         2-835
            890-1129            BE332650.1         240-479
            1130-1134           AL590969.12        221847-221851
            1135-1255           AL590969.12        221956-222076
            1256-1562           AL590969.12        222866-223172
            1563-1770           AL590969.12        223835-224042
            1771-1898           AL590969.12        224339-224466
            1899-2031           AL590969.12        224735-224867
            2032-2490           AL590969.12        225055-225513
            2491-2682           AL590969.12        225829-226020
            2683-3068           AL590969.12        226462-226847
FEATURES             Location/Qualifiers
     source          1..3068
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 64.32 cM"
     gene            1..3068
                     /gene="Plekhh3"
                     /note="pleckstrin homology domain containing, family H
                     (with MyTH4 domain) member 3"
                     /db_xref="GeneID:217198"
                     /db_xref="MGI:MGI:2384950"
     exon            1..648
                     /gene="Plekhh3"
                     /inference="alignment:Splign:2.1.0"
     CDS             487..2868
                     /gene="Plekhh3"
                     /note="isoform 2 precursor is encoded by transcript
                     variant 2; pleckstrin homology domain-containing family H
                     member 3; PH domain-containing family H member 3"
                     /codon_start=1
                     /product="pleckstrin homology domain-containing family H
                     member 3 isoform 2 precursor"
                     /protein_id="NP_001333698.1"
                     /db_xref="CCDS:CCDS83899.1"
                     /db_xref="GeneID:217198"
                     /db_xref="MGI:MGI:2384950"
                     /translation="MPLPGGLWWLLCCRRGFTLLHRDYGDGELSGDGDEDEDDETFEL
                     RTPSPAGGGRGSLDVTLTQPTRNGPISDRLQGWEETWSLIPDKGLPEEDPDIIVKGWL
                     YREPRGGGARPWLLPRRAWFVLTRDSLDQFSSSGKGARRLGSLVLTSLCSVTGPERRP
                     KETGLWSVTVSGRKHSIRLCSPRQAEAERWGVALREVIASKAPLETPTQLLLRDIQES
                     CGDPEAVALIYRRNPILRHTSSALYAPLLPLPYEVSAPGPGYAPLREEAVRLFLALQA
                     LEGARRPGPLMQGVLQTCRDLPALQDELFLQLAKQTSGPAGPPGLPATQDPATLRYWQ
                     LLTCMSCTFRPGGAVRGHLLGHLERTEQALPDSELAEYARFIRKALGRTRGRELVPSL
                     AEISALSRRQELLCTVHCPGAGACPVSIDSHTTAGEVARELVGRLGLARSRNAFALYE
                     QRGAQERALAGGTLVADVLTSLTSEEAGLEDSPDCGWRLCLRLHGPLHPEGLSPEGHE
                     LPFLFEQAHALLLRGRPPPPEDTLRALAALRLQSLHRDFSPRGPLPLLDRLLPPPIPP
                     REQPPCPTRRPPPSAALLAGALWSPGLAKRRAERARRGGTGRSTGSTAQVGGGGASTT
                     AAVLGGWKRLRGMGQAEAMAAYLALAAQCPGFGAARYDVLELSTEPGGGAPQKLCLGL
                     GAKAMSLSRPGETEPIHSVSYGHVAACQLIGPHTLALRVGDSQLLLQSPQVEEIMELV
                     NAYLANPSPERPCRSGSSSGPPSQDLPDTSPPSQHQVLEEPQGQSGCLKQLQD"
     exon            649..704
                     /gene="Plekhh3"
                     /inference="alignment:Splign:2.1.0"
     exon            705..784
                     /gene="Plekhh3"
                     /inference="alignment:Splign:2.1.0"
     exon            785..976
                     /gene="Plekhh3"
                     /inference="alignment:Splign:2.1.0"
     exon            977..1134
                     /gene="Plekhh3"
                     /inference="alignment:Splign:2.1.0"
     exon            1135..1255
                     /gene="Plekhh3"
                     /inference="alignment:Splign:2.1.0"
     exon            1256..1562
                     /gene="Plekhh3"
                     /inference="alignment:Splign:2.1.0"
     exon            1563..1770
                     /gene="Plekhh3"
                     /inference="alignment:Splign:2.1.0"
     exon            1771..1898
                     /gene="Plekhh3"
                     /inference="alignment:Splign:2.1.0"
     exon            1899..2031
                     /gene="Plekhh3"
                     /inference="alignment:Splign:2.1.0"
     exon            2032..2490
                     /gene="Plekhh3"
                     /inference="alignment:Splign:2.1.0"
     exon            2491..2682
                     /gene="Plekhh3"
                     /inference="alignment:Splign:2.1.0"
     exon            2683..3068
                     /gene="Plekhh3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3042..3047
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Plekhh3"
                     /note="hexamer: AAGAAA"
     polyA_site      3068
                     /gene="Plekhh3"
                     /note="major polyA site"
ORIGIN      
        1 ggggggcaga gagggaggcg gggtctggga actctgcccg cgcccccaac gcgccagtcc
       61 cggggctgca gggagcgcag cgcgcgccgc ccgggccccg gccaccggac gccctaccgg
      121 acaccaccct ccttggagct tggacaaccg cccaccacga ttgctgcacc agacactgct
      181 cctacagagc tggacactac aacgaacact acttcccagc tccggacatt gctcccggct
      241 cccttccccc ggccctggac gctatctccc ccctcctctg cccgggccca gacagcgagc
      301 ccccagcggg ctctggtgat agtccttttg cacctcagcg ctggacactg cctccttccg
      361 gcccccttct ttcctctcgt cacacctctt ctctacccag ttcgggtcgg agtacctcca
      421 gtttctcaga ttccctgctg ctcaggcaac actgcctgcg cccccattcc caggctgctc
      481 gcccggatgc ctctccccgg gggattgtgg tggcttctct gctgccgtcg aggcttcact
      541 cttctgcacc gggactacgg ggacggcgag cttagcgggg acggggacga agacgaggac
      601 gacgagacct ttgagctaag gaccccgagt ccagcgggcg gcgggagggg ttccctggac
      661 gttactctga ctcagccaac aaggaatggg cccatctcag acagactgca gggctgggaa
      721 gagacctgga gcctcatccc agacaaggga cttccggaag aggaccctga catcattgtg
      781 aaaggttggc tgtaccggga acctcgtgga ggaggggcaa ggccatggtt actcccacgc
      841 agagcctggt ttgtgctcac cagagattcc ctggaccagt tcagcagcag cgggaagggg
      901 gcaaggcgac tcggaagcct ggtcctcaca agcttgtgct cagtgactgg gccggagcgt
      961 aggcccaagg agactggtct gtggtcagtc actgtgtctg gccggaaaca cagcatccgc
     1021 ctctgctctc cgcgccaggc agaggcagag cgctgggggg tagcactgcg ggaggtgatt
     1081 gcctccaaag ctccgctgga gacccctacc caactgctgc tcagggacat ccaggagagc
     1141 tgtggagacc cagaagcagt ggccctcatc taccggcgga acccaatcct gaggcacacc
     1201 agtagtgcct tgtatgcccc gctcttgccc ctgccctatg aagtcagcgc tccaggtcca
     1261 ggctacgcac ccttacgaga ggaggcagtg aggctgttcc tggcactgca ggcgctggag
     1321 ggggcacggc gcccagggcc cctgatgcag ggtgtgctcc agacctgccg ggacctgcct
     1381 gcactccagg acgaactttt cctgcagctg gctaagcaga cctcaggtcc tgcaggtccc
     1441 cctgggctcc ctgccactca agatcctgca accctgcgat actggcagct tctcacttgc
     1501 atgagctgca ccttccggcc ggggggagct gtccgagggc acctcctagg gcatttggaa
     1561 aggacggagc aggcactccc agactcagaa ctggcagaat atgcacgctt catccggaag
     1621 gctctgggcc gtacacgggg ccgagagctg gtgccttcac tagcagagat ttccgcactg
     1681 agcagaaggc aggagctgtt gtgtactgtg cactgtcccg gagctggagc ctgtcctgtg
     1741 tctatcgact cccacactac agcgggagag gtggctcgag agttggtggg caggctaggt
     1801 ttggcccgga gccggaacgc attcgctttg tatgagcagc gaggagccca ggagcgagcc
     1861 ctggctgggg ggaccctcgt ggccgacgtg ctcaccagtt tgacttcgga ggaagccgga
     1921 ctggaggact cgccggactg cgggtggaga ctgtgtcttc gtcttcacgg acctctgcac
     1981 ccagaagggc tatctccaga gggtcacgaa ttgcctttcc tctttgagca ggctcacgct
     2041 ctgctgctgc gcggccggcc gcccccaccc gaggacacgc tgcgcgccct ggcggcgctg
     2101 cgcctgcaga gtttgcaccg ggacttttcc ccgcggggac ccctgccgct cctggaccgc
     2161 ctgctgccac cccccatccc gccgcgcgaa caaccgccgt gccctacccg aaggccaccg
     2221 ccctccgctg ccctgctggc cggggcgctc tggagccccg gcctggccaa gaggcgggcc
     2281 gagcgtgccc ggcgcggcgg aaccggccgc tctacgggaa gcacggccca ggtgggaggt
     2341 ggcggcgcca gcacgacggc tgcggtgctg ggcggctgga agcggctgcg gggcatgggc
     2401 caagctgaag ccatggctgc ctacctggct ctagcggcgc agtgtccggg gttcggcgct
     2461 gctcggtatg acgttctgga gctgagcacg gagcctggtg gaggtgctcc acagaagctc
     2521 tgcctgggtc tgggagcaaa ggccatgtcg ctctccaggc ctggtgagac agaacccatc
     2581 cacagtgtca gctatggtca tgtggccgcc tgccagctaa taggccctca caccttagca
     2641 ctgagggtgg gcgacagcca gctcctcctg cagagtcccc aggtggaaga gatcatggag
     2701 ctggtgaatg cctacttggc caacccctcc cccgagaggc cctgccgcag tggcagcagc
     2761 tctggtcctc caagccaaga cctgccggac acctcccctc ccagccagca ccaagttctg
     2821 gaagagcccc agggacagtc tggctgcttg aagcagctgc aggactaagc ctgccaagag
     2881 gtcaggactt ttcttttgcc tccagcctga gaccggactg ctctgagatt tgaggcaacc
     2941 atggaccctt tttttggccc tgcagggaca gggtacaccc acacccgagg gcagcaatgg
     3001 gtgtggacag ttttctagtt tgtttcttaa tttatttgta gaagaaaaaa aatcgttatt
     3061 tacacaaa
//
