LOCUS       NM_177606               6886 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus pleckstrin homology domain containing, family H (with
            MyTH4 domain) member 2 (Plekhh2), transcript variant 1, mRNA.
ACCESSION   NM_177606
VERSION     NM_177606.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6886)
  AUTHORS   Shalom-Barak,T., Zhang,X., Chu,T., Timothy Schaiff,W., Reddy,J.K.,
            Xu,J., Sadovsky,Y. and Barak,Y.
  TITLE     Placental PPARgamma regulates spatiotemporally diverse genes and a
            unique metabolic network
  JOURNAL   Dev Biol 372 (1), 143-155 (2012)
   PUBMED   22967998
REFERENCE   2  (bases 1 to 6886)
  AUTHORS   Perisic,L., Lal,M., Hulkko,J., Hultenby,K., Onfelt,B., Sun,Y.,
            Duner,F., Patrakka,J., Betsholtz,C., Uhlen,M., Brismar,H.,
            Tryggvason,K., Wernerson,A. and Pikkarainen,T.
  TITLE     Plekhh2, a novel podocyte protein downregulated in human focal
            segmental glomerulosclerosis, is involved in matrix adhesion and
            actin dynamics
  JOURNAL   Kidney Int 82 (10), 1071-1083 (2012)
   PUBMED   22832517
  REMARK    GeneRIF: Suggest a structural and functional role for Plekhh2 in
            the podocyte foot processes.
REFERENCE   3  (bases 1 to 6886)
  AUTHORS   Brunskill,E.W., Georgas,K., Rumballe,B., Little,M.H. and
            Potter,S.S.
  TITLE     Defining the molecular character of the developing and adult kidney
            podocyte
  JOURNAL   PLoS One 6 (9), e24640 (2011)
   PUBMED   21931791
REFERENCE   4  (bases 1 to 6886)
  AUTHORS   Nishimura,M., Yokoi,N., Miki,T., Horikawa,Y., Yoshioka,H.,
            Takeda,J., Ohara,O. and Seino,S.
  TITLE     Construction of a multi-functional cDNA library specific for mouse
            pancreatic islets and its application to microarray
  JOURNAL   DNA Res 11 (5), 315-323 (2004)
   PUBMED   15747579
REFERENCE   5  (bases 1 to 6886)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC139329.3 and AC132353.3.
            
            On May 16, 2008 this sequence version replaced NM_177606.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK029252.1, BC125583.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-70                AC139329.3         126063-126132
            71-200              AC139329.3         135864-135993
            201-263             AC132353.3         113620-113682       c
            264-413             AC132353.3         103624-103773       c
            414-497             AC132353.3         101572-101655       c
            498-579             AC132353.3         100976-101057       c
            580-759             AC132353.3         97148-97327         c
            760-1724            AC132353.3         94210-95174         c
            1725-1800           AC132353.3         91194-91269         c
            1801-1895           AC132353.3         90009-90103         c
            1896-2040           AC132353.3         89333-89477         c
            2041-2177           AC132353.3         86078-86214         c
            2178-2288           AC132353.3         85868-85978         c
            2289-2375           AC132353.3         85342-85428         c
            2376-2534           AC132353.3         83829-83987         c
            2535-2615           AC132353.3         77600-77680         c
            2616-2795           AC132353.3         74669-74848         c
            2796-2904           AC132353.3         71652-71760         c
            2905-3017           AC132353.3         70273-70385         c
            3018-3197           AC132353.3         69429-69608         c
            3198-3295           AC132353.3         64840-64937         c
            3296-3473           AC132353.3         63070-63247         c
            3474-3629           AC132353.3         61855-62010         c
            3630-3727           AC132353.3         60363-60460         c
            3728-3869           AC132353.3         54183-54324         c
            3870-4015           AC132353.3         50243-50388         c
            4016-4145           AC132353.3         49378-49507         c
            4146-4232           AC132353.3         44882-44968         c
            4233-4367           AC132353.3         43079-43213         c
            4368-6886           AC132353.3         39003-41521         c
FEATURES             Location/Qualifiers
     source          1..6886
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 55.02 cM"
     gene            1..6886
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /note="pleckstrin homology domain containing, family H
                     (with MyTH4 domain) member 2"
                     /db_xref="GeneID:213556"
                     /db_xref="MGI:MGI:2146813"
     exon            1..70
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            71..200
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     CDS             78..4553
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /note="isoform 1 is encoded by transcript variant 1;
                     pleckstrin homology domain-containing family H member 2"
                     /codon_start=1
                     /product="pleckstrin homology domain-containing family H
                     member 2 isoform 1"
                     /protein_id="NP_808274.2"
                     /db_xref="CCDS:CCDS28999.1"
                     /db_xref="GeneID:213556"
                     /db_xref="MGI:MGI:2146813"
                     /translation="MEEPSEPEGLIDWKERCVALEAQLMKFRVQASKIRELLADKMQQ
                     LERQVIDAERQAEKAFQEVQVMEEKLKAANIQTSESETRLYKKCQDLESVMQEKDDII
                     QNLALRLEEQKQVRIQEAKIIEEKAAKIKEWVTVKLNELEVENQNLRFINQTQTEEIR
                     AIQSKLQELQEKKISCVSSPKTSEGQRNLTFGCFLSRAKSPPCVVRCEEVSKMASNEP
                     EITEGRCVEEMEIAEKPADNQVQENSRSQRKLHETSCSSEQNQKTRASFAMDGGTSQN
                     SGVPVSDWSSDEDDGSKGRSKSRCTSTLSSHTSEEGGQCGRLGSEAYLTASDDSSSIF
                     EEETFDGNRPEQKKLCSWQQKAPWKAQGNLAKGRSQSGVKEQDSSSDELNKKFHSQRL
                     DYTSSSSEANTPSPILTPALTPRYPNSLPGKGGAPLVPPPFQPPPKLRVPNVFSISVA
                     LTKRHLSQPQLCSDRMFGTNRNAISMIRPLRPQETDLDVVDGDGAEAVNRMDTGCDDG
                     LFSYDSQDPPPCADDQENSEAPKKAPCNKPPTPPLHRFPSWESRIYAVAKSGIRVSEA
                     FNMEHANKNSADILSYSAASLYTSLIYKNMTTPVYTTLKGKATQISSSPFLDDSSGSD
                     EEDSSRSSSRLSESDARSRSGPSSPRAMKRGVSDSSAASESDYAIPPDAYPIDAECSQ
                     PEQKLLKTCLASCDNGKNEPLEKSGYLLKMSVRVKTWKRRWFVLKGGELLYYKSPSDV
                     IRKPQGHIELSASCSILRGDNKQTVQLATEKHTYYLTADSPNILEEWIKVLQSVLRVQ
                     AANPLCLQPEGKPAVKGLLTKVKHGYSKRVWCMLVGKVLYYFRNQEDKFPLGQLKLWE
                     AKVEEVDRSCDSDEDYETRGCYLLSTHYTIIVHPKDQGPTYLLIGSKHEKEAWLYHLT
                     VAAGSNNINVGSEFEQLVCKLLNIEGEPSSQIWRHPMLCHSKEGILSPLTTLPSEALQ
                     TEAIKLFKTCQLFINAAVDSPAIDYHISLAQSALQVCLTHPELQNEICCQLIKQTRRR
                     QLQNQPGPLQGWQLLALCVGLFLPHHPFLWLLQLHLQRNADSRTEFGKYAIYCQRCVE
                     RTQQNGDREARPSRMEILSTLLRNPYHHSRPFSIPVHFMNGLYQVVGFDASTTVEEFL
                     NTLNQDTGMRKPAQSGFALFTDDPSGRDLEHCLQGNIKICDIISKWEQASKEQQPGKC
                     EGSRTVRLTYKNRLYFSVQARGETDREKTLLLYQTNDQIINGLFPLNKDLALEMAALL
                     AQVDIGDFERPFSTPAGPVTNQCKANQTLKQVIERFYPKRYREGCSEEQLRQLYQRLS
                     TKWMALRGHSAADCIRIYLTVARKWPFFGAKLFFAKPIAPSSLGNNCVWLAVHENGLS
                     ILEYTSMRLVTSYMYKGLMTFGGYQEDFMVVVSTQSKDRPTEKLLFAMAKHKILEITL
                     LIASYINSFHQQKTTFHHLSAPALLSPRTQAPQARVMGSQPPLSNSRPTKGPTLL"
     exon            201..263
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            264..413
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            414..497
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            498..579
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            580..759
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            760..1724
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            1725..1800
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            1801..1895
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            1896..2040
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            2041..2177
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            2178..2288
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            2289..2375
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            2376..2534
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            2535..2615
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            2616..2795
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            2796..2904
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            2905..3017
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            3018..3197
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            3198..3295
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            3296..3473
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            3474..3629
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            3630..3727
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            3728..3869
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            3870..4015
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            4016..4145
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            4146..4232
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            4233..4367
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     exon            4368..6886
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6854..6859
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /note="hexamer: AATAAA"
     polyA_site      6873
                     /gene="Plekhh2"
                     /gene_synonym="E030001K05; mKIAA2028"
                     /note="major polyA site"
ORIGIN      
        1 gggctgagag ccggggaagc cggcggagcc gggtgactgg cgagccggaa catcaggcgc
       61 cgccgcagag aagaactatg gaggagccct ctgagccaga aggactaata gactggaaag
      121 agcgctgcgt agctctggag gctcagctca tgaaattccg agttcaagca agcaagatcc
      181 gcgagctctt agcagacaaa atgcaacagt tggagagaca agttatcgat gcagagcggc
      241 aagcagaaaa ggcttttcaa gaggtacaag ttatggaaga gaaactaaaa gcagctaata
      301 ttcagaccag tgagtcggag acacggctct ataagaagtg tcaggacctg gagtccgtga
      361 tgcaggagaa ggatgacatc attcagaact tggcgctgcg gcttgaagag cagaaacaag
      421 tgaggataca agaagctaaa ataatagaag aaaaagcagc taagatcaaa gaatgggtaa
      481 cagttaagtt aaacgagcta gaagtagaga atcagaatct tcgtttcatc aaccagaccc
      541 agactgaaga gataagagcg atacagtcca agttgcaaga actccaagag aagaagatat
      601 cctgtgtctc ctcaccaaag acctcagaag ggcaacgcaa tttgacattt ggatgcttct
      661 tgtcccgagc aaagagtcct ccttgtgtcg taagatgtga ggaagtgagc aagatggcct
      721 caaatgaacc tgagatcacg gaaggaagat gtgtagaaga gatggaaatt gcagagaagc
      781 ctgctgacaa ccaagtccaa gagaacagca gaagccagag aaagttgcac gagacctctt
      841 gcagctcgga acagaaccag aaaacgagag caagctttgc aatggatggt ggtacgtccc
      901 agaattctgg ggttccagtg agtgactgga gttcagacga ggatgatgga agcaagggca
      961 gatctaagtc caggtgcacg tccacccttt ccagccacac atctgaggag ggtggccagt
     1021 gcggcaggct gggcagcgaa gcctacctca cagcatctga tgacagtagt tctatattcg
     1081 aagaagagac ttttgatggg aatagacctg agcaaaagaa gctgtgttct tggcagcaga
     1141 aggcaccatg gaaagctcag ggtaaccttg caaaagggag gtctcagtca ggagtaaagg
     1201 agcaagatag ttcctcagat gaactgaata agaaatttca ctcgcagaga ctggattata
     1261 catcctcatc cagcgaggcc aacaccccaa gccctatttt aaccccagct ttaactccca
     1321 ggtaccctaa ctcactccct ggaaaaggag gagccccgtt agtgcctcct ccattccagc
     1381 cacccccaaa gctcagggtc cccaacgttt tcagtataag tgtggcactc accaagagac
     1441 acctgagcca gccacagcta tgctccgatc ggatgtttgg cacgaaccgg aacgccataa
     1501 gcatgatccg gccgctgagg ccccaggaaa cggaccttga tgtggttgat ggggacgggg
     1561 ccgaggctgt gaacagaatg gacactggtt gcgatgacgg cttattttcc tatgactccc
     1621 aggatcctcc tccgtgtgca gatgaccagg aaaacagcga ggccccaaag aaggccccat
     1681 gcaacaaacc ccctactcct cctctgcacc gcttcccctc ttgggagagc aggatatatg
     1741 ctgtagccaa atcaggcatc cgggtgtctg aggccttcaa tatggagcat gctaataaaa
     1801 attctgcaga catactttcc tactctgcag caagccttta tacgtctctc atatacaaga
     1861 acatgacgac cccagtctat acaacgttga aggggaaggc gacacaaata agtagcagcc
     1921 ctttcctgga tgactcctcg ggctcagacg aagaggacag ttctaggtcc agctcccggc
     1981 tgtcggagtc agatgcgcgc agtcgcagtg ggccaagcag tcccagagcc atgaagcgag
     2041 gcgtgtctga ctcctccgca gcttctgaaa gtgactatgc cattcctccg gatgcctatc
     2101 ccatagacgc agagtgttcg cagcccgagc agaaacttct aaaaacctgc ctggcctcct
     2161 gtgacaatgg gaaaaatgaa ccattagaaa aatctgggta cctactgaaa atgagcgtga
     2221 gagtcaagac ttggaagcgg aggtggtttg ttctgaaagg aggcgaatta ctttactaca
     2281 agtcaccaag cgatgtgatt cggaaacccc agggccacat tgaactgagt gcatcctgca
     2341 gtattttacg gggcgataac aagcaaacgg ttcagctggc cacagagaag cacacatact
     2401 atctgacggc ggattctccc aatatactgg aagaatggat caaagtgtta cagagcgttc
     2461 tgcgagtaca agctgcgaac cctctttgcc tgcagcctga gggcaaaccc gcagtaaagg
     2521 gcttgctcac caaggtgaag catggctact ctaagagggt ctggtgcatg cttgttggaa
     2581 aggtcttgta ttatttccgc aatcaagagg ataagttccc tctaggtcag ctcaaactct
     2641 gggaggctaa ggtggaagag gtggacaggt cctgtgactc cgacgaggac tatgagaccc
     2701 gggggtgcta tctgctgtcc actcactaca ccatcattgt ccaccccaaa gaccagggcc
     2761 ctacttacct gctcatcgga tctaagcacg agaaggaagc ttggctgtat cacctcactg
     2821 ttgcagctgg aagcaacaat ataaatgttg gatccgaatt tgaacaactg gtttgcaagt
     2881 tgctgaatat agaaggggag ccctcctccc agatatggag acaccccatg ctgtgtcaca
     2941 gcaaagaagg aattctgtcc cctctgacca cactgccttc ggaagctctg cagaccgagg
     3001 ccattaagct atttaagacc tgccagctct ttataaacgc tgcggtcgac tcccctgcca
     3061 tcgactacca catctctcta gcccagagcg ctctgcaggt ctgcctgacg catcccgagc
     3121 tacagaatga aatctgctgc cagcttatta agcagacaag acggagacag ctgcagaacc
     3181 agccaggccc gctgcagggt tggcagctct tggcactctg cgttggactc ttccttcccc
     3241 accacccttt cctgtggctc ctccagctcc atctacaaag gaatgcagat tccaggacag
     3301 agtttgggaa atatgccatt tactgccagc gatgtgtaga aaggacacag caaaacggag
     3361 accgagaggc cagaccgtcc aggatggaga tactctccac tcttcttcga aacccctacc
     3421 accattctcg gcccttcagc atacccgtgc acttcatgaa cgggctctac caggtagtgg
     3481 ggttcgatgc gtccaccaca gtggaagaat ttttgaacac tctgaaccag gacacaggaa
     3541 tgaggaagcc ggcacagtct ggattcgcac tcttcacaga tgatccttct ggcagagacc
     3601 tggagcactg tcttcaggga aatatcaaga tctgtgacat tatttctaaa tgggagcagg
     3661 catccaaaga acagcagcca ggcaagtgtg agggcagccg gactgtccgt ctgacttaca
     3721 aaaacagact gtatttctca gtgcaagctc gtggagaaac cgatagagag aagacgctgc
     3781 tgctgtacca gacaaatgac caaatcataa acggcctttt tcctctgaat aaggatctgg
     3841 cgttagaaat ggcagcgctt ttagctcagg tggatattgg agattttgaa agacctttct
     3901 caactccagc ggggcctgtg actaaccagt gcaaggcaaa tcaaaccctc aaacaagtca
     3961 tagagagatt ttacccgaaa aggtaccgag aagggtgctc tgaggagcag ctaaggcagc
     4021 tctaccagcg actctcaacc aaatggatgg ccctccgggg acacagtgcg gctgactgca
     4081 ttcgaattta cttgacagta gccaggaagt ggccgttctt tggcgccaag ttgttctttg
     4141 caaaaccaat agcaccatca tcacttggca ataattgcgt gtggctggct gtccatgaaa
     4201 atgggttgag catcctagaa tacacctcca tgagattagt gaccagctat atgtacaaag
     4261 gtctgatgac ctttgggggc tatcaagagg atttcatggt agtcgttagt acacagtcaa
     4321 aagaccggcc aacagagaag ttactttttg cgatggcaaa acacaagatt cttgaaatca
     4381 cccttctgat cgccagttac atcaacagct tccatcaaca gaagacaacg tttcaccacc
     4441 tctctgcccc agcgctgctc tcacccagga cccaggcgcc ccaagccagg gtcatgggca
     4501 gccagccccc tctgtccaac agcagaccta ccaaaggccc taccttactc tgactcctga
     4561 gcctggacct tcactcctcc accacatggt tgcatctgct gcaagtgttt acacccggcc
     4621 aacatggtgc atgcacacat cagcactcca gaccttagca gtaatgggct actctcttat
     4681 ctgactctta atatttacat aacaataaac acaaaccgtg tcaacacact cattgtgtct
     4741 tagacaaagt aggttagaat ttgtcttttt ttttcccacc cccatctccc ttcttggcca
     4801 tcagagattg tgcagtaagg cttcccagct tgcttttaaa catcctggca atcttttaaa
     4861 ggggagattc caaactctca cttggtaaac tagatgactg tctggaaaag ctcactgcca
     4921 aagaatgcaa ggattgtaat caaatgtgcc tttagctaat gaagccatct ttaggaagga
     4981 gtgaggtttc gtgtgggaac ataggcagag ggcaaactct tagagcaagc gcaatgaatt
     5041 gtctgaggct gggcctcatt ccatgagatg acaggccacc aaccagagcc accttggctg
     5101 ggggtttgga agtttgtatc ctgccacttc tgcggatgtg gagtgtgtca tttaaaatga
     5161 ggtatggagt ccaggcagcc ctgcctgtca gcatagccta agatcattgg aacagtgccc
     5221 cacattcaca agtgtttaat gctagcccag cttgaccttg ctttgttgtg gtgtctttgg
     5281 aaacaaagat atcccttaaa gccttgtcct tcacacggtc ttttctaatt ctctaattaa
     5341 aaatggattc caaagtaaat tctaatagag aaaacttcag ccaaagtcag tacattttga
     5401 gttgaactcg tctgaggata tcctagttat cccacggcca aggcaaaatg cttggcaaaa
     5461 acagcctaag cgagacatga ttgttttggc tgttttagag aggtctgtcc ctggtggctt
     5521 ggccctgtgc agttggtggc aggaacatgt ggcataagag gtttcttcaa ctcatggtag
     5581 agaggaagca gagaacaagg aagggacccg agacaggagc aacttcaaaa gcatgtcact
     5641 agtgacttaa ttcctctaag ttccaactct caaaatgcct accacctttc aaactagcac
     5701 accatctgcg ggccaagcgt tggacacatg agcctctggg aacatttcat ggttaaatcc
     5761 taacagctac gtcagtggcc aatacatttc aaactgtgtc aaggcgatgt aattagtatt
     5821 cctgataacg tgaaactgtg ataagatatg aaaattctat tataattatg tttaaccaca
     5881 agtctaccta attttattta tgtgtagaat acttgtattt atttttagac atatatttat
     5941 cactgttgtg ctatatgctt taaactgatt tgagaatgtg ctaggtgccc aatgaagttg
     6001 ttggcagagt ccctgtgtcg tcattgtctt tgctgtggca gtgtcccgtt ctcacactaa
     6061 gccttttaaa catgctctgc cctgaggagc aaagccagga agcatgttgc tccagccata
     6121 ctgtactgcc ttggtaatga caaaggtatt tttcaagccc catagagaag gccttcaagt
     6181 ggccgttcac ccttccgtct tttaaaccac aaccactcac tgaatgaaca gattcgtttt
     6241 taagaacaaa tgattaacaa tttggggtga ctttcagagt gggataaagt agtgtttttg
     6301 tgtgcccatt tactaatcat tagtgggcga ggcagaggct ggggcaaagc tctgacttac
     6361 aggtgcgaac tttactctca cccaacagtc ccttcaccaa ctggtaagca gttccacctg
     6421 ccatatcttg agatttaaaa gtagtgagtg ctcaggtggg gcggtggtgg cccatgcctt
     6481 tagtcccagc acttgggagg cagaagcagg cagatttctg agttcgaggc cagcctcatc
     6541 tacagagtga gagccaggac acagggctac acagagaaac cctgtctcga aaacaaaaca
     6601 aaagtagtga gtgctcacct tcaactacag tgccttaagc tttgtccttg ttttttatag
     6661 agcagaaata aaatattttg atggaaagga ctcagttttg aacaatcagt gatgtgaaaa
     6721 tttgatctcc tgggaaattc cttccatagc cattttttaa agcaagtgta ttattatgat
     6781 tgattacaag agaataatgt ttcatgtcta attgtaatat ttctcaacta cccttttctc
     6841 ccctcacagt tacaataaat gattttcgag ttccgtttcg aacatt
//
