LOCUS       NM_181073               6451 bp    mRNA    linear   ROD 29-OCT-2024
DEFINITION  Mus musculus pleckstrin homology domain containing, family H (with
            MyTH4 domain) member 1 (Plekhh1), mRNA.
ACCESSION   NM_181073 XM_126961 XM_904513
VERSION     NM_181073.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6451)
  AUTHORS   Gomez-Del Arco,P., Isern,J., Jimenez-Carretero,D.,
            Lopez-Maderuelo,D., Pineiro-Sabaris,R., El Abdellaoui-Soussi,F.,
            Torroja,C., Vera-Pedrosa,M.L., Grima-Terren,M., Benguria,A.,
            Simon-Chica,A., Queiro-Palou,A., Dopazo,A., Sanchez-Cabo,F.,
            Jalife,J., de la Pompa,J.L., Filgueiras-Rama,D., Munoz-Canoves,P.
            and Redondo,J.M.
  TITLE     The G4 resolvase Dhx36 modulates cardiomyocyte differentiation and
            ventricular conduction system development
  JOURNAL   Nat Commun 15 (1), 8602 (2024)
   PUBMED   39366945
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6451)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 6451)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ106785.1, AK143387.1, AA072901.1, CF538481.1 and BQ031023.1.
            
            On or before Aug 30, 2009 this sequence version replaced
            XM_904513.3, XM_126961.8, NM_181073.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK122464.1, SRR1660811.251998.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-258               CJ106785.1         2-259
            259-5413            AK143387.1         76-5230
            5414-5584           AA072901.1         199-369
            5585-6106           CF538481.1         120-641
            6107-6451           BQ031023.1         1-345               c
FEATURES             Location/Qualifiers
     source          1..6451
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 35.51 cM"
     gene            1..6451
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /note="pleckstrin homology domain containing, family H
                     (with MyTH4 domain) member 1"
                     /db_xref="GeneID:211945"
                     /db_xref="MGI:MGI:2144989"
     exon            1..258
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            259..429
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            430..492
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            493..642
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            643..726
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            727..808
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            809..1563
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            1564..1645
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            1646..1737
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            1738..1888
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            1889..2016
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            2017..2127
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            2128..2214
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            2215..2376
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            2377..2457
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            2458..2640
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            2641..2749
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            2750..2862
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            2863..3039
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            3040..3137
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            3138..3315
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            3316..3471
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            3472..3572
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            3573..3714
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            3715..3857
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            3858..3987
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            3988..4074
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            4075..4221
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     exon            4222..6439
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6411..6416
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /note="hexamer: AATAAA"
     polyA_site      6433
                     /gene="Plekhh1"
                     /gene_synonym="D630024D12Rik; mKIAA1200"
                     /note="major polyA site"
ORIGIN      
        1 gtgcctggcc gcgagctgcc cgccgagcga gcgcggtgcg gacacagccg gcgcggcgct
       61 gctcccagcg ctggggcggg ctttgtgcgg agctccgggg accttccagg ctccgacctc
      121 ggcccgccac gcccaccgcg acccctgcag cgggggagcg gagacccggg ggcctctccg
      181 cactcgggga gagccactgt ggggcagagg cgcgcgtggc ggtcggggtc gcggcgggac
      241 tcccggcagc tcactcagtg tgctggatct tggagctccc gggagtattt ggaagttggt
      301 tccgtcatgg cagaagtcaa ggtggaggtg gccagcatag actggcagaa gcgatgccta
      361 tccctggaaa cacagctttt ccgcttccgc cttcaggcca gcaagataag ggagctgctg
      421 gctgacaaga tgcaggagct ggagcagagg ctgctggagg ctgagcagag agctgaaaat
      481 gcagaaactc aggtgggtgt gatggaagag aagataaaac tgtccaatct gaagagtgtg
      541 gactccacag gtaccttgca ccaaaagtac caagaattgc tgagagccgt tcaaggcaag
      601 gacgagctca tcagccagct gcaggcacag ctggagaagc agaagcagac aagagctgaa
      661 gaagccaaaa ttgttcaaga aaaagctgca aagatcaagg aatgggtgac agtaaagtta
      721 gcagagcttg aaatggaaaa tcaacagctg aagacttgta accagcagct agtggagcag
      781 gtggcggccc ttcaggatgc tcttgaggat cttcgaatga cgccttcaga ggagctgcta
      841 gttgttcctg agggaacccc agagagggat cctgtccctt cagggcccag tgaccagcct
      901 gtggagcagg acagtaatcc ccatacccag attttgaagg tggctgtgcc tacaccttct
      961 ctgggtaccc tgcagagcag ggactccctg tcagaagcca gaagtcttga ggatttgcgt
     1021 ttcagcatgg tccatcctgg ggaaacagca gaggccaaga cccttcagtc tcatcttcag
     1081 aaagagggct ctcccagtca gctgtgcatg aagcctggca accccaagca tgggtcagcc
     1141 tcttacagag aaagtctggt cactgctcag ggagggacat tccctgggac caagacctct
     1201 gccagggaag gtggccctgg tagtagcctg accctgccaa aggtgcgggc tcccagcatc
     1261 cctcgggaca gcttccaagt ggccaaaagg caccacagtc agccccaggt aggccctggg
     1321 cattgtgacc acgtggtaag cattgagatt ggggcgctgt cagccctcca ctcacctggc
     1381 tcctccaagt ctgaagccag agctaaagtc cgggaagaag cagagaagat ggagatggag
     1441 gcgctgcctc catcagggaa gcaggaagag agagagagcc tcaagtcccg cagaggtgaa
     1501 ctggaggacg tggaactgga gaacaagcca cctacacccc cactgcacag gtttccatct
     1561 tgggagagca ggatctacgc gatggccaca tcaggcatgc agctgtcaga agtgtcatca
     1621 cgacgaagta atgctgcctg ctacgcttcg gggccgtctg cccttgcatt ccctggagct
     1681 ttctctggcc ttgtctacaa gaatgtcact gtgcctgtct acacagcact gaaggggaaa
     1741 gccacgcaga tcagcaatgt gccttttgtg gatgagtcct ccgggtctga tgatgactgc
     1801 ggctctcaag caagtttccg gatgtcagtc ccctgctctg agtacaggaa gaccagtgga
     1861 ctaggcagcc cccgggccat caagagaggg gtctccatgt cctcactgag ctctgagggt
     1921 gactatgcta tccctcctga cgcctgctca ctggacagtg actactcaga gcctgagcac
     1981 aaactccagc gtacttcatc gtactccacc gacggggagg cactggaaaa gtcaggctac
     2041 ctgctgaaaa tggggagccg ggtgaagaca tggaagaggc gctggtttgt cctgagacag
     2101 ggacaaatcc tatactacaa gtctccgagt gacgtcatcc ggaaacctca gggtcaagtg
     2161 gatctgaatt ctcactgcca gattgttcga gaggaggaag cacagacgtt tcagctcatc
     2221 tctggaaaca aaacctacta cctaacagca gagtccccca gcctcctgga agaatggatc
     2281 cgtgtcctac agagcctgct gaaggtgcag gtcactggcc ctccagccct gcatcaaggg
     2341 ggcaccaagc ctactgtgaa gggctggctg accaaggtaa agcatggcca ctccaagctg
     2401 gtctggtgcg ccctggttgg gaaaaccttc tactactacc ggagccacga ggacaagaga
     2461 cccctgggct gcctacctgt gcaggacgct cacatagagg aagtagatcg gtcctgtgac
     2521 tcggacgaag actatgaagc tggaggaacc gggcgcttgc tgtcctccca ctgcacgctg
     2581 gtgatccacc ccccggagca cagccccacc tacctcctca tcggcaccaa gcatgaaaag
     2641 gatacgtggc tttaccacct cacagtggct gcaggtggca gcaatgccaa ggtgggcact
     2701 gtctatgagc agctcattgg gaaactgatg gatggtgagg gtaacccaga ctccccactc
     2761 tggaggcacc ccatgctgtg ctacagccaa gaagggctat gcgcctccct taccaccttg
     2821 ccctccgagg ccctgcagac ggaggccctg aagctcttca agtcctgcca gctcttcatc
     2881 aatgtgccgg tggaagccgc ctcagtagac taccatgtgt ccctggctca gacggccctg
     2941 caggtgtgcc tcgttcaccc tgagctacag agtgagatct actgccagct catgaagcag
     3001 atcagctgtc gcccgcctca gaagtactct cttatgcaat gctggcagct cctggctctg
     3061 tgtgccccac tcttcctgcc tcagcaccac ttcctctggt atgtcaaaca gcagctccaa
     3121 cgccatgcag accccagaag tgaaactggt cagtatgcta tatactgcca gcgagccgtg
     3181 gagcgaaccc tgcagacagg agaacgggag gccaggccat cacggatgga agtagtgtcc
     3241 atcttgctac gaaacccctt ccatcactcc ttacccttca gcatccctgt gcactttgcc
     3301 aatggaactt accaggtggt tggttttgat ggctcctcca cagtggatga gttcctccag
     3361 cggctgaacc aggaaacggg catgaggaag ccctcccagt ctggctttgc cctctttacg
     3421 gatgatcctt ctggcaggga cctggagcac tgtcttcaag ggcgtgtcaa gatctgtgac
     3481 gccatctcca agtgggagca aacgctgaag gagctgcatc ctgggaagtc tgagggtggg
     3541 acacgagtcg tgaagctgat gtacaagaac aggctgtact ttcgaagtca agtcaaaggg
     3601 gagacagaga gagagcggct gctacttgcc ttccaagcca gtggagaaat agtggcagga
     3661 agatttccag tcaccaagga actggccctt gaaatggctg ccttgatggc ccaggtggag
     3721 tatggggact tggagaagcc tacgctgcca ggccctgggg gtacacctcc caccaaagcc
     3781 cagcatctcc ttcagcaggt ccttgacagg ttttacccaa ggcgctatcg aaatggagca
     3841 ccccctgagc agctgaggca cctggcagac atgatggcca ccaagtgggc agcgttacaa
     3901 ggctgctccc ctcccgagtg catccgcatc tacctgactg tggctcggaa atggcctctc
     3961 ttcggggcta agctcttcgc tgctcagcct gcccagctgt ctcctaagga gaacactgtg
     4021 gtgtggattg ctgtgaatga ggatggtgtc agcatcctgg accaccgcac catgcaggtg
     4081 aacatcactt atccctactc ttcagtgaca acgttcggtg gctgcaggga tgacttcatg
     4141 cttgtgatta gatccattcc agaccagagc tctggaaaaa cccgtattga caagttgacc
     4201 ttccgaatgc ctgctcccaa gattacagaa actaccttaa tgatggccag ctacatgaac
     4261 cactgttctg caactgtgaa cctatcagcc aagctccctg cagcccgcca gccccgagac
     4321 ctggatggac agttctttgc ttctgtttcc tgcactaagg ggtcagcttt gctgtgaaca
     4381 tttctcctcc ccataccctt gccaccactc gtgcctctgg gatcagattg ataccctgga
     4441 gcatacacta ctgtgatggg tctaatggcc cctcctcaaa ctgttctgtg aattgtgaat
     4501 tccagggtct ctgaaacctt tgtgctcttt aggtgcctta cctttcaagg cccaatgttc
     4561 taagattcag acccaacatc aaaaccacta ttttacaaga atactgactc tggatgctac
     4621 ctgattctag atagagacag ggatggccca cagttaccag ggcaatggta ctgtatttgg
     4681 ggcttctgca ctgatactca gggaagctca tctttttata ttatacatgg tctttacgtg
     4741 gggacttata cttgaagttt tctgaacatc cctgaataaa aataggacta aaattcctaa
     4801 tttacctaaa ctctggcaaa tgcctacaaa tctctaaaac tggacttctt tcccaaatgg
     4861 gaaaaaccct ggccaagctg gagaaggaaa gaatgacgag ccctccccta ttggtgagga
     4921 ggcatttgcc atgccctttt gggctctaat cttttcagga ctgtacagta ttcctgttaa
     4981 gattaaagct tttcctctca cactggacta gcacaggcag ggacagagcc agtctgcacc
     5041 cttcctgtgt cattttaagg cccaacaagg ctcagtgaag cctgtgctca ctactgaagg
     5101 acgaggtggt catcatctcc tattctctcc aagaccaagc acataaattt tgcttgttgc
     5161 tgctctaaga ggccaccaga gaaacaagat atcaggaaca ctaaagaccc ttccattctt
     5221 ggaaggcctg gattgctcac taagactttt ggtagagggc ttctcgaaat tagttggaag
     5281 cacagggcat gtacatatct gtggaagtag aaagtttctt tcaactttgc cttcctgaga
     5341 atattatcat ccctctcaac gcaaaccttt tagttgattt tgatgaagat gatctttctt
     5401 tccatctttc cccacaaaat aataataata aaaaaacaag tccatacttt ggttttccaa
     5461 catataaaaa ataagcttta ttgtgtagct ttaaggcagt tttattattt ttcagtaaca
     5521 tagactaggg gataagagga atatcaagaa ataagccttt aacccaacaa tgtgtgtgtt
     5581 gtacaccaca agaaactgca aggccaaaaa ttagtttaat ctgaatgcct cagctgctgt
     5641 aatccctcat cctttgaact gacaagcctg actttaaaaa ggcacaagag tctgcccctt
     5701 aaaaagagct tgacttgcaa gccaggcagc tttatagcca tttctgtttg aaccccaact
     5761 cccaccccag atttggggtt ctagaggaga caggtctacc tcaagtcaca ttgctatagg
     5821 cccctggaca gctccttcaa ggctaggtga agggcagaga atgcagttct tggtttacat
     5881 cccaagggcc ttaaagccag taaggatgta gtctgctctc aggttgtttt tgttttgtaa
     5941 acagaattcc agctaatgca actgtttgta agacttgaag gtctgattag ctactgctgc
     6001 tgtgctgctg cttttttttt tcctttctct tgctctcttt ttgagatagg gtttcactat
     6061 gcagacctgg ctgtcctgga actcactatg tagaccaggc tggcctcaaa ctcagagatc
     6121 cgcctgcctc tgcctctgca gtgctggggt taaaggcgag ttctgcccag tccagcgcct
     6181 tttctccttc ctgatcttta gcatctaagg aaccacctct gaaacaaagg cttctgtcaa
     6241 ctggcttcct catcctttaa tgtgacaggc tcatgtctgg gaaccaacat ttaatctctc
     6301 actcttcacc taagccctct tagccaaaca gcttttgagc aatagaaaat attaacagaa
     6361 aggtactctc atgcttgaca cccatggctg aaatgctatg tatgtttgtc aataaaactg
     6421 tcagtgaacc agacaataaa aaaaaaaaaa a
//
