LOCUS       NM_198604               3019 bp    mRNA    linear   ROD 01-FEB-2024
DEFINITION  Mus musculus pleckstrin homology domain containing, family G (with
            RhoGef domain) member 6 (Plekhg6), mRNA.
ACCESSION   NM_198604 XM_132888
VERSION     NM_198604.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3019)
  AUTHORS   Wu,D., Haruta,A. and Wei,Q.
  TITLE     GIPC1 interacts with MyoGEF and promotes MDA-MB-231 breast cancer
            cell invasion
  JOURNAL   J Biol Chem 285 (37), 28643-28650 (2010)
   PUBMED   20634288
  REMARK    GeneRIF: GIPC1-MyoGEF complex formation plays an important role in
            regulating MDA-MB-231 breast cancer cell polarization and invasion.
REFERENCE   2  (bases 1 to 3019)
  AUTHORS   Wu,D., Asiedu,M., Adelstein,R.S. and Wei,Q.
  TITLE     A novel guanine nucleotide exchange factor MyoGEF is required for
            cytokinesis
  JOURNAL   Cell Cycle 5 (11), 1234-1239 (2006)
   PUBMED   16721066
REFERENCE   3  (bases 1 to 3019)
  AUTHORS   Yoshizawa,M., Sone,M., Matsuo,N., Nagase,T., Ohara,O., Nabeshima,Y.
            and Hoshino,M.
  TITLE     Dynamic and coordinated expression profile of dbl-family guanine
            nucleotide exchange factors in the developing mouse brain
  JOURNAL   Gene Expr Patterns 3 (3), 375-381 (2003)
   PUBMED   12799088
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC140324.3 and AK153619.1.
            
            [WARNING] On Apr 2, 2024 this sequence was replaced by NM_198604.3.
            
            On Jan 19, 2008 this sequence version replaced NM_198604.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments and orthologous data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC026778.1, AK153619.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-54                AC140324.3         2661-2714
            55-883              AK153619.1         345-1173
            884-884             AC140324.3         7418-7418
            885-2513            AK153619.1         1175-2803
            2514-2802           AC140324.3         19835-20123
            2803-3010           AK153619.1         3098-3305
            3011-3019           AC140324.3         20506-20514
FEATURES             Location/Qualifiers
     source          1..3019
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 59.32 cM"
     gene            1..3019
                     /gene="Plekhg6"
                     /gene_synonym="Gm155"
                     /note="pleckstrin homology domain containing, family G
                     (with RhoGef domain) member 6"
                     /db_xref="GeneID:213522"
                     /db_xref="MGI:MGI:2682298"
     exon            1..155
                     /gene="Plekhg6"
                     /gene_synonym="Gm155"
                     /inference="alignment:Splign:2.1.0"
     exon            156..377
                     /gene="Plekhg6"
                     /gene_synonym="Gm155"
                     /inference="alignment:Splign:2.1.0"
     exon            378..586
                     /gene="Plekhg6"
                     /gene_synonym="Gm155"
                     /inference="alignment:Splign:2.1.0"
     exon            587..742
                     /gene="Plekhg6"
                     /gene_synonym="Gm155"
                     /inference="alignment:Splign:2.1.0"
     exon            743..907
                     /gene="Plekhg6"
                     /gene_synonym="Gm155"
                     /inference="alignment:Splign:2.1.0"
     exon            908..1003
                     /gene="Plekhg6"
                     /gene_synonym="Gm155"
                     /inference="alignment:Splign:2.1.0"
     exon            1004..1054
                     /gene="Plekhg6"
                     /gene_synonym="Gm155"
                     /inference="alignment:Splign:2.1.0"
     exon            1055..1204
                     /gene="Plekhg6"
                     /gene_synonym="Gm155"
                     /inference="alignment:Splign:2.1.0"
     exon            1205..1315
                     /gene="Plekhg6"
                     /gene_synonym="Gm155"
                     /inference="alignment:Splign:2.1.0"
     exon            1316..1465
                     /gene="Plekhg6"
                     /gene_synonym="Gm155"
                     /inference="alignment:Splign:2.1.0"
     exon            1466..1603
                     /gene="Plekhg6"
                     /gene_synonym="Gm155"
                     /inference="alignment:Splign:2.1.0"
     exon            1604..1723
                     /gene="Plekhg6"
                     /gene_synonym="Gm155"
                     /inference="alignment:Splign:2.1.0"
     exon            1724..1856
                     /gene="Plekhg6"
                     /gene_synonym="Gm155"
                     /inference="alignment:Splign:2.1.0"
     exon            1857..1972
                     /gene="Plekhg6"
                     /gene_synonym="Gm155"
                     /inference="alignment:Splign:2.1.0"
     exon            1973..2124
                     /gene="Plekhg6"
                     /gene_synonym="Gm155"
                     /inference="alignment:Splign:2.1.0"
     exon            2125..2802
                     /gene="Plekhg6"
                     /gene_synonym="Gm155"
                     /inference="alignment:Splign:2.1.0"
     exon            2803..3019
                     /gene="Plekhg6"
                     /gene_synonym="Gm155"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggccccgtg ctgcctggtc ccgcgggccg ctcggtccta gtcccaggct gggacagtgg
       61 ggctgccatc gccaaggaag ctgacaacga cccagatttc cacagtatcc agcggacgtc
      121 aaggacagcg gaagctcgga cacctgcgct cacaggccct gcccactgca agggatgggt
      181 cttccatcca ggcttagaaa ggaggggtgg agtcctgcat ctgacttcca gctctatccc
      241 tggtggtgcc ctcggcggcc aggaaaggag cttagtggga gaccagcggg ctgcctcaac
      301 taggggcatc cctccagacc ctgtctgaca gctctcctga cttcgccaga ttgtacgtgg
      361 acgtgtgggg tttccagaaa aggggatacc cccctttctc ctggacattg gtgctatgat
      421 cctctggggg taactcagga gagaaacaat gcaagccttt ggtcctccaa atgagggccc
      481 cctccaaggc ctggtagctt cccgaattga gacttacggg ggccgtcatc agacctctgc
      541 ccacagcact gctgggaatc tatttcccag aggaggtcct ggagtggacc ctagtcgccg
      601 acgccttcag cactatgtcc cctttgccaa gggctctggc cagacccgag gcatgtctcc
      661 tctggtgctt cgggaaccag acccagagaa gaggcatgga agctattttg gggtcggccc
      721 acctcactcc cccaaactca aggaagtcac cagggcccat gagctagaaa taaggctgca
      781 cacattcagc atgtttggga tgccccgcct gccaccagag gaccggagac actgggagat
      841 aggagaggga ggcgatagtg ccctgaccat ggaaaagtcc tggaaggagc tggtgctgga
      901 acacaaggag atgaaccgcc agctttgcca ccagcaggaa gcactgtggg aactcctgac
      961 cactgagctg atctacctga gaaagctcaa gatcatgact gatctcctgg cagctggtct
     1021 gctgaatttg cagcgggtgg ggctgctgac tgaggtgtcg gctgagaccc tgtttggaaa
     1081 tgtccccaac ctgattagag cccaccggag attttgggag gaggtgctgc agcccatcct
     1141 ggaagacact cgcacctctg gccaaccttt ggatcctgtc agcttacaaa atggcttcct
     1201 gacatttggc cagcggttcc aaccttacgt ccagtactgc cttcgagtaa agcagaccat
     1261 ggcttatgcg cgggagcagc aagacacgaa cccactgttc cacaccttcg tgcagtggtg
     1321 tgagaaacac aagcgctccg gaagacagac gctgggtgac ttgctcatca agccccacca
     1381 gcgcatcacc aaatacccac tgctgctgca ggctgtgcgc aagagaagcc ccgagccccg
     1441 agcccaagag gccctgaatg ccatgatcga ggctgtggag tccttcctgc gacacataaa
     1501 tggccaggtc cgacagggtg aagagcagga gagtttgatg gctgtggccc agcgcatagg
     1561 accctatgag gtgctagagc cctccagcga ggaggtggag aagaacctgc gtccattctc
     1621 caccctggat ctgatgactc ctgtactagg ggttgcccct gagtatacca ggcagctgct
     1681 gctggaagga cctgtgcggg tgaaggaggg acgagaaggg aagatggatg tgtacctatt
     1741 tctcttctcc gatgtgctcc tggtaaccaa acctcaacgc aaggcggaca gagccaaggt
     1801 catccgtcct cccctcatgc tggagaaact cgtgtgccga ccactgcgag accccaacag
     1861 cttcctgttg atccacctca cagaattcca gtgtgtctcc agtgccctca ctgtgcactg
     1921 tcccagttct acagagcgtg cacggtggct ggagaagacc cagcatgctc agaccactct
     1981 gcagaagctg aagggtgagc agtacattca acagaagagg gagctgctgg ccctctatcg
     2041 caaccagggc acggagtccc ccagcaccag gccctccaca ccttcgcctt ccccggagga
     2101 ctcccagagc agtgccgagg ggaggacttt agagttcgcc atcatccccc gcctggtggt
     2161 gactgaggat acagatgaag acacgccctc catgccggat gacgcctcag actctggcta
     2221 cggtaccttg attccaagct ccccgaagga ttctcattcc cccctgaaca ggcttcggtc
     2281 caaggctctt cgtagagacc ctcgcctcac cttctccacc ctggaactca gagacgtccc
     2341 cttgcgcccc cagcctcccg acccccaagc tccccagcgg cgaagcgccc cagagttgcc
     2401 agaagggatc ctaagaggag gcagtctacc caggagagcc ccaccaatct ggtcggagga
     2461 ggaagacgag actttggcat cagggaatgt ggtggtagaa accctacaca gggcgcaacg
     2521 tcggagtccg ctcccccact ctcccactca tactgactct gctggggaaa gcccctggga
     2581 gtcctcagat gaagatgagg ggcttctatc ccctgaactc cgcccccgct ccctacggga
     2641 ggacatgctc agggagatca gggaggagct ggccaaccaa aggatcgatg gagcctcgga
     2701 accggaacca gggaatggca agccccggag gctgactcta gcccagctgc agagaatgag
     2761 ggtcccccac atcatacagc tggacacgcc cctgtctaca tcagaagtat aaggaatgct
     2821 gaggcccttt gatacacctc ctagagaaat tgtctcccta agagtgctgg ccaccacctc
     2881 ccccggactc tacctcaagg atccacctca aaccaagcct gacccaggca tcacctctga
     2941 ggaccctgga ggtcaagaac tgaacatttt gtctcacaga cgaacccctg agccctatat
     3001 aaaagtgccc agaaacatg
//
