LOCUS       NM_153804               6411 bp    mRNA    linear   ROD 13-FEB-2025
DEFINITION  Mus musculus pleckstrin homology domain containing, family G (with
            RhoGef domain) member 3 (Plekhg3), transcript variant 2, mRNA.
ACCESSION   NM_153804 XM_126990
VERSION     NM_153804.5
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6411)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6411)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   3  (bases 1 to 6411)
  AUTHORS   Nguyen,T.T., Park,W.S., Park,B.O., Kim,C.Y., Oh,Y., Kim,J.M.,
            Choi,H., Kyung,T., Kim,C.H., Lee,G., Hahn,K.M., Meyer,T. and
            Heo,W.D.
  TITLE     PLEKHG3 enhances polarized cell migration by activating actin
            filaments at the cell front
  JOURNAL   Proc Natl Acad Sci U S A 113 (36), 10091-10096 (2016)
   PUBMED   27555588
  REMARK    GeneRIF: PLEKHG3 enhances polarized cell migration by activating
            actin filaments at the cell front.
REFERENCE   4  (bases 1 to 6411)
  AUTHORS   Ray,J.P., Staron,M.M., Shyer,J.A., Ho,P.C., Marshall,H.D.,
            Gray,S.M., Laidlaw,B.J., Araki,K., Ahmed,R., Kaech,S.M. and
            Craft,J.
  TITLE     The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling,
            Differentiation, and Metabolism of T Helper 1 and Follicular B
            Helper T Cells
  JOURNAL   Immunity 43 (4), 690-702 (2015)
   PUBMED   26410627
REFERENCE   5  (bases 1 to 6411)
  AUTHORS   Dietrich,J.E., Panavaite,L., Gunther,S., Wennekamp,S., Groner,A.C.,
            Pigge,A., Salvenmoser,S., Trono,D., Hufnagel,L. and Hiiragi,T.
  TITLE     Venus trap in the mouse embryo reveals distinct molecular dynamics
            underlying specification of first embryonic lineages
  JOURNAL   EMBO Rep 16 (8), 1005-1021 (2015)
   PUBMED   26142281
REFERENCE   6  (bases 1 to 6411)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC163033.4.
            
            On Mar 28, 2022 this sequence version replaced NM_153804.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC096443.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-263               AC163033.4         137070-137332
            264-653             AC163033.4         163643-164032
            654-751             AC163033.4         165720-165817
            752-821             AC163033.4         167269-167338
            822-868             AC163033.4         167611-167657
            869-1019            AC163033.4         167771-167921
            1020-1151           AC163033.4         168016-168147
            1152-1334           AC163033.4         168312-168494
            1335-1427           AC163033.4         168673-168765
            1428-1514           AC163033.4         169006-169092
            1515-1548           AC163033.4         169298-169331
            1549-1647           AC163033.4         169682-169780
            1648-1737           AC163033.4         174601-174690
            1738-1776           AC163033.4         175118-175156
            1777-1796           AC163033.4         175564-175583
            1797-2060           AC163033.4         175909-176172
            2061-2174           AC163033.4         176761-176874
            2175-3594           AC163033.4         179371-180790
            3595-6411           AC163033.4         181189-184005
FEATURES             Location/Qualifiers
     source          1..6411
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 33.73 cM"
     gene            1..6411
                     /gene="Plekhg3"
                     /note="pleckstrin homology domain containing, family G
                     (with RhoGef domain) member 3"
                     /db_xref="GeneID:263406"
                     /db_xref="MGI:MGI:2388284"
     exon            1..263
                     /gene="Plekhg3"
                     /inference="alignment:Splign:2.1.0"
     exon            264..653
                     /gene="Plekhg3"
                     /inference="alignment:Splign:2.1.0"
     CDS             303..4328
                     /gene="Plekhg3"
                     /note="isoform 2 is encoded by transcript variant 2;
                     pleckstrin homology domain-containing family G member 3;
                     PH domain-containing family G member 3"
                     /codon_start=1
                     /product="pleckstrin homology domain-containing family G
                     member 3 isoform 2"
                     /protein_id="NP_722499.4"
                     /db_xref="CCDS:CCDS25994.1"
                     /db_xref="GeneID:263406"
                     /db_xref="MGI:MGI:2388284"
                     /translation="MPVSTALHQDGSQERPRSLVSTTSSSGSSRDSHSAMEEPTGSEA
                     SAQNGTGSPWDRHVPNSNNNSSGWLNMKGPLSPFNGRAGTSPAYHKLSYLGRVVREIV
                     ETERMYVQDLRSIVEDYLLKIIDTPGLLKPEQVSALFGNIESIYALNSQLLRDLDSCN
                     SDPVAVASCFVERSQEFDIYTQYCNNYPNSVAALTECMQDKQQAKFFRDRQELLQHSL
                     PLGSYLLKPVQRVLKYHLLLQEIAKHFDEEEDGFEVVEDAIDTMTCVAWYINDMKRRH
                     EHAVRLQEIQSLLINWKGPDLTTYGELVLEATFRVHRVRNDRTFFLFDKILLITKKRG
                     DHFVYKGHIPCSSLMLIESTRDSLCFTVTHYKHSKQQYSIQAKTVEEKRSWTHHIKRL
                     ILENHHATIPQKAKEAILEMDSYYPSRYRCSPERMKKAWSSQDEVSSHVRQGRRQSEP
                     GHTLFSRATLPSRQQGFEMPGLKGRRKSEPTRHLLRQLSEKARAVGMKHAGSAGALLD
                     FGQPAHAQKQQPEAERAAREELEEEEELVEEEEQRQQSFSGSLEGLAGHDGSEKVPGP
                     ELPGSEEEEEEEESLAVAEQGKRHRESEGSKGCRRPSNRSPTSAEKRMSFESVSSLPE
                     VETDPEPGAEQEAFAALEGPSTEEMPSDPEFPEALETQLHAPKGLLGVDNPAAVVDFV
                     EPEGSEDLKPLSSEEEEEEEMEAAQEPESLLPPSVLDQASVIAERFASSFSRRSSLAI
                     EDGKSSGLGTPRLISRSSSVLSLEGSDKGLARWSSIGDSLSNPPTPEVIIGADMVTDN
                     GPSVNGTESPSAGSGCPTEQDRSSCKKKESALSTRDRQLLDKIKNYYENAEHHDAGFS
                     IRRRESLSYIPKGLVRSSVSRFNSLPKPDSEPAAPVGYKRPGSSRPASWTLFDLPGPR
                     TDKGDPAPITDAEFCPSSEIAKIWERMESSERSPRTGSGQSQANGFELQEPLFILEEH
                     ELGAITEESAVASPESASPTEQPSPAHLARELKELVKELSSSVQGELVTPLHPRIVQL
                     SHVMDSHVSERVKNKVYQLARQYSLRIKNIKAARPPLQWEKVTPDQEEQVPSISGLPE
                     EAGELSGGKARRKPVLSLLSYEQLVAQEHGTSKSSAAVETSPRRFSFSPSAVSPRTTS
                     PGARSSARSPLSPFDTETFNWPDVRELCSKYTSHDKTAQVESSWPRSLLVNRSRSLPE
                     NIVEPPMSGKADRCCGLNTHRRLGDGEASQPPLPESPPQSQLNGGDALYVTADLTLEN
                     NQRVIIMEKGPHPSSTVGLEEDSGKESSSPVALKGQGQGFQASAEYQPKEHGPRDSAD
                     TNKQGRVRNLREKFQALNSVG"
     exon            654..751
                     /gene="Plekhg3"
                     /inference="alignment:Splign:2.1.0"
     exon            752..821
                     /gene="Plekhg3"
                     /inference="alignment:Splign:2.1.0"
     exon            822..868
                     /gene="Plekhg3"
                     /inference="alignment:Splign:2.1.0"
     exon            869..1019
                     /gene="Plekhg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1020..1151
                     /gene="Plekhg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1152..1334
                     /gene="Plekhg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1335..1427
                     /gene="Plekhg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1428..1514
                     /gene="Plekhg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1515..1548
                     /gene="Plekhg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1549..1647
                     /gene="Plekhg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1648..1737
                     /gene="Plekhg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1738..1776
                     /gene="Plekhg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1777..1796
                     /gene="Plekhg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1797..2060
                     /gene="Plekhg3"
                     /inference="alignment:Splign:2.1.0"
     exon            2061..2174
                     /gene="Plekhg3"
                     /inference="alignment:Splign:2.1.0"
     exon            2175..3594
                     /gene="Plekhg3"
                     /inference="alignment:Splign:2.1.0"
     exon            3595..6411
                     /gene="Plekhg3"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      4962
                     /gene="Plekhg3"
                     /note="major polyA site"
     regulatory      6390..6395
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Plekhg3"
                     /note="hexamer: AATAAA"
     polyA_site      6411
                     /gene="Plekhg3"
ORIGIN      
        1 ccctccctcc cgccgcagcc tggactccgg ccgcaacttc ctgcccggtg ctggggaacc
       61 gtgcgcattt cgggggtccc ccggcgtctg gtgctcgcag cgagcagagg ctgggaccgc
      121 ggggcggcca gccgtgggcg ggagcggccg gcggcctctg ccgcttccga gagcgacttt
      181 caaactcgag cccgcttcgc ggcgccacct gggcagcccc gcgcgcctgg cgcgtcgcga
      241 gccggcgggg cggccaccgc ttgaatctcc ccgaggtgac agccccaggc agcgatgcca
      301 ggatgcccgt ctccactgcc ctccaccaag atggcagcca ggagcggcca cgaagcctag
      361 tgtccaccac ttcttcatct ggctcctccc gtgacagtca cagtgccatg gaggagccca
      421 ctggctcgga ggcttcagcc cagaatggga caggctcccc ttgggaccgg catgttccca
      481 acagcaacaa caactccagt ggctggctga acatgaaggg acctctctcc ccattcaacg
      541 gccgtgcagg gacaagtcct gcctaccaca agctcagcta tctgggccgg gtggtgagag
      601 agatcgtgga aacagagcgc atgtatgtgc aggacctacg gagcattgtg gaggactacc
      661 tcttgaagat cattgacact ccaggactcc tgaagccaga gcaagtcagc gccctctttg
      721 ggaacataga gagcatatat gcactgaaca gccagcttct cagagacctg gacagctgca
      781 atagtgaccc tgtggcagtg gccagctgct tcgtggaaag gagccaagag tttgatatat
      841 acactcagta ttgcaacaac taccccaact cagtggcagc cctcacagag tgcatgcaag
      901 acaagcaaca agctaagttc ttcagagatc ggcaggagct gctgcagcac tccctgcctc
      961 tgggctccta cctgctgaag ccggtccagc gcgtcctgaa gtaccacctg ctgctccagg
     1021 aaattgccaa acattttgat gaggaagagg atggcttcga ggtggtggag gatgccatcg
     1081 acaccatgac gtgcgtggcc tggtacatca acgacatgaa gaggaggcat gagcacgcag
     1141 ttcggctaca ggagatccag tcactgctca ttaactggaa gggaccggac ctgaccactt
     1201 acggggagct ggtcctggaa gccacctttc gtgtgcaccg cgtgcgcaat gacagaactt
     1261 tcttcctctt tgacaagata ctgctcatta ccaagaagcg aggcgaccac tttgtctaca
     1321 agggccacat tccgtgctcc tcactgatgc tgatcgaaag caccagagac tctctctgct
     1381 tcactgtcac ccactataag cacagcaaac aacaatacag tatccaggcc aagaccgtgg
     1441 aggagaaacg gagctggact caccacatca agaggctcat cttggagaac caccatgcca
     1501 ccatacccca gaaggccaag gaagccatct tggaaatgga ctcctattat cccagtcggt
     1561 atcgctgcag cccagagcgg atgaaaaagg cctggtcctc ccaggatgag gtgtctagcc
     1621 acgtgcgcca aggacgtcgg cagtctgagc ctggtcatac cctgttcagc agggcaacac
     1681 tccccagcag gcagcaagga ttcgagatgc caggccttaa gggccgtaga aagtcggagc
     1741 ccaccagaca cctgctcagg caactgagtg agaaagccag agcagtggga atgaagcatg
     1801 caggcagtgc tggagccctc ttggactttg ggcagccagc ccatgcacag aagcagcagc
     1861 cagaggctga gagggccgcc agggaagagc ttgaggaaga ggaggagctg gtggaggagg
     1921 aagaacagcg gcagcagagc ttctcgggct ccctggaggg ccttgcaggg catgatggca
     1981 gcgagaaggt gcctgggcca gagctcccgg gctcggagga ggaggaggag gaagaagaga
     2041 gtctagcagt ggcggagcag gggaagagac acagggagtc tgaaggctct aaaggctgca
     2101 gaaggcccag taaccggtcg ccaaccagtg cggagaagcg catgagcttt gagtctgttt
     2161 cttccctgcc agaggttgag acagatcctg agcctggggc cgagcaggag gcctttgcgg
     2221 ccttggaagg tcccagcaca gaggagatgc cttcagaccc agaatttcca gaagccctgg
     2281 agacacagct tcatgccccc aaggggctgc taggagtgga caacccagct gctgtggtgg
     2341 actttgtgga gcctgagggg tctgaagacc ttaagcccct gagtagtgag gaggaagaag
     2401 aagaggaaat ggaagccgcc caggagcctg agagcctcct gccaccctct gtgctggacc
     2461 aggccagtgt cattgctgag agattcgcca gtagcttctc tcggcggagc agcctggcaa
     2521 tagaggatgg caaatccagt ggtttaggga caccacggct tatcagccgg agcagcagtg
     2581 tgcttagcct ggagggcagt gataagggcc tagcccgatg gagcagcatc ggggactccc
     2641 tcagcaaccc acccacccca gaagtgatca ttggtgcaga catggtcaca gacaatggcc
     2701 cttctgtcaa tgggacagaa tctccaagtg caggctcagg ctgccccacg gaacaggaca
     2761 gatcttcctg taagaaaaaa gaatcagcgt tgtctacccg agaccgtcag ctgctggaca
     2821 aaattaagaa ctactatgaa aatgcagagc accatgatgc tggcttcagc atccgtcggc
     2881 gggagagcct ctcctatatc cctaaaggat tggtgcgcag ctctgtgtcc agattcaaca
     2941 gccttcccaa gccagattca gagccagcag ctccagttgg gtacaagagg ccggggagtt
     3001 ctcgtccagc ctcatggacc ttgtttgacc ttccaggtcc caggacagac aaaggggacc
     3061 cagctcctat cacagatgct gagttctgtc catcttcaga aattgcaaag atatgggaaa
     3121 gaatggagtc ttcagagaga agtccacgga cagggtctgg ccagagccag gccaatggct
     3181 ttgagctaca agagccactg ttcatcttgg aggagcatga actgggggcc atcactgagg
     3241 agtctgctgt cgcctctcca gaaagtgcct cccccaccga gcaacccagc ccagcccacc
     3301 tggcccggga gctcaaagag ctggtgaaag agctgagcag cagtgtccag ggggagctgg
     3361 ttaccccact gcacccccgg attgtgcagc tctcccatgt gatggacagc catgtgagtg
     3421 agcgggtcaa aaacaaggtc taccagttgg cccgccagta cagcctccga attaagaaca
     3481 tcaaggcagc taggccacct ctacagtggg aaaaagtcac tcctgaccaa gaggagcagg
     3541 tcccttccat ttctggcctg cctgaggaag ctggagagct gtcagggggc aaagccagga
     3601 ggaagcctgt gctatccctc ctcagctatg agcagctggt ggctcaggag catggcacgt
     3661 ccaagtcttc cgctgccgtg gaaacctctc cacgccgttt ctccttcagc ccttctgctg
     3721 ttagcccaag aaccacctca cctggggctc ggtcctctgc tcggagcccc ctcagcccct
     3781 ttgacaccga gaccttcaat tggcctgatg tccgggagct ctgctccaaa tatacttccc
     3841 acgacaagac tgctcaggtc gagagcagct ggccccgtag cctgctggtc aacaggagtc
     3901 gctccctgcc cgagaacatc gtagaacctc ccatgtctgg caaggcggac cgctgctgtg
     3961 gcctgaacac ccacaggcgc ctgggagatg gggaagcctc ccagcctcca cttcctgagt
     4021 ctcctcccca aagccagctg aatggaggcg acgccctgta tgtcaccgca gaccttaccc
     4081 tggagaacaa ccagcgagtg atcattatgg agaaggggcc ccatcctagc tccaccgtgg
     4141 ggctggagga agacagtggg aaggaatcaa gttccccagt ggctttgaag ggacagggcc
     4201 aaggtttcca ggcgtctgca gagtaccagc ccaaagaaca cggtcccagg gactcagcag
     4261 acacaaacaa acagggtaga gtgagaaacc tgagggagaa gttccaggcc ttgaactctg
     4321 tgggttgatt gactcctaaa ggagagaaca gccacgtgga ggttggaagg acctggcatg
     4381 ctccccccac acccacaccc ccctaggcct ggctcattaa ggctgatcct ccactcttct
     4441 ggaagagtgg tttggagtgg agtgtgaact cacctgttac ctgtgctggc ccctcccctc
     4501 ccctcccctg ggaggtccca ggatgactga ctttccttag gtccagatga gctacttacc
     4561 ttctctgtaa atacttctct gataagaagc caactgtttt atcctgccca gggagggcga
     4621 gcactgccct ggctttcctt actggctggc cactgcctgg ctgagaaccc aagggagaga
     4681 cctaggaagc agcccgggca ggctttgccc tttaactgcc ttgtcatagg acccaggcag
     4741 gaatgaggcc aataatttat tgctttatat cctgtggtgt gtgtgtgggt gtgtgtgtgt
     4801 gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtcttgta aagaatgtaa tggacttagt
     4861 tcaggtactc tcgaaggttg tcttgctggc cctgtggtgg ttgccaatgg acacacattt
     4921 cattctttac ctatggtata ataaccactg ctgaccaacc aacctgtgtg tggcctcctt
     4981 cctggggaca tggatgctca ctcaaatgtc cgggcacagc agacaagata acaagggtgc
     5041 tcacgggtca ggtggggtac agagtgtgag gtgggatctt gattcctccc atgtttgcct
     5101 ctgtgcattg ctttgtccac ccaaagcgtc atgttctgtc tcgggtgaga ttcccacatg
     5161 ggagccttga gctcttttcc caaagacaaa gttgggaaaa gctggaaccg acagggcgag
     5221 cagaaccctt cagataaacg gggttttcta gggtccagtg acttttactc atctctccct
     5281 ctcaggtccc caggagtggg tgagggtcct aaggttgagg cttagcaatg tcctaaagtg
     5341 gtctgcagcg ttgtggagtg taagtgtatt ttattggaat ggttcctgtt ctcaacagca
     5401 cccacagaag tgtctggttg caaaaggcca ggaatgcccc atttctaaat gggctttttt
     5461 tctgcacaga agaccagctt tactttggtt tctgtctagg gtcagaaaag agggccttgg
     5521 tgacagacca gtccttctag tgtacctgca agtctgcagg gagtaaaacc tgggcatctt
     5581 tcaatctaag aggatggatt ggattggatc tgaacatagg atgaccatca acccccaccc
     5641 caccctgata tcgggtgagt ggtggtctcc tgggcaggaa cagagcaggc ctgcagtagc
     5701 ccatgccctc tcggtcctct gcaaccactg tcagtcactg agaagacagc tactgttttt
     5761 gagcaggcca gtcccaggat atgacacctg ataacggcca taaaagcatt ggatgggtga
     5821 ctctaagtct tgtcccagcc ttgctaccag ctgggtcacc caactatgta ctttcctcat
     5881 ctacagattg aaggctggat gaatcactgt ttctcaaact caatgacagc atccaggggt
     5941 ggagcctggg cagttgtggc taatgtcttt tgggtgatcc ttacagtcca agtgtaggtg
     6001 tgtctaggaa ccttggacag ggacagttgc attcacaggc tcctattaga attacctgaa
     6061 gaccctctga aacctggcag tcccatgtct cacccaggcc aaataaaact gcccctctga
     6121 aaatggatcc caggacagat aggagatcag gtccctgctc ctggtagtta acagcctgaa
     6181 cagtagattg cttagagaca actttggcct cgagttgatt gaactcatga aacgaacaag
     6241 cttcctcagg gtcccagatg ggatctagtg cctggatacc agcagtcatc ccataatact
     6301 ctgaggaaca aagtaaaacc ctagctgtct ctctgtttcc atggtatctt ccctctgatg
     6361 tccagttcaa aggaacaaga ggctggtcaa ataaacagag acaaacacag a
//
