LOCUS       NM_001164361            6723 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus pleckstrin homology domain containing, family A
            (phosphoinositide binding specific) member 8 (Plekha8), transcript
            variant 1, mRNA.
ACCESSION   NM_001164361
VERSION     NM_001164361.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6723)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6723)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   3  (bases 1 to 6723)
  AUTHORS   West,D.B., Engelhard,E.K., Adkisson,M., Nava,A.J., Kirov,J.V.,
            Cipollone,A., Willis,B., Rapp,J., de Jong,P.J. and Lloyd,K.C.
  TITLE     Transcriptome Analysis of Targeted Mouse Mutations Reveals the
            Topography of Local Changes in Gene Expression
  JOURNAL   PLoS Genet 12 (2), e1005691 (2016)
   PUBMED   26839965
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6723)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 6723)
  AUTHORS   D'Angelo,G., Uemura,T., Chuang,C.C., Polishchuk,E., Santoro,M.,
            Ohvo-Rekila,H., Sato,T., Di Tullio,G., Varriale,A., D'Auria,S.,
            Daniele,T., Capuani,F., Johannes,L., Mattjus,P., Monti,M.,
            Pucci,P., Williams,R.L., Burke,J.E., Platt,F.M., Harada,A. and De
            Matteis,M.A.
  TITLE     Vesicular and non-vesicular transport feed distinct glycosylation
            pathways in the Golgi
  JOURNAL   Nature 501 (7465), 116-120 (2013)
   PUBMED   23913272
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK078040.1, BB647122.1 and AC084800.5.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK078040.1, AK170592.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849377, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-334               AK078040.1         2-335
            335-342             BB647122.1         191-198
            343-600             AK078040.1         343-600
            601-2228            AK078040.1         602-2229
            2229-6723           AC084800.5         146677-151171
FEATURES             Location/Qualifiers
     source          1..6723
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 27.02 cM"
     gene            1..6723
                     /gene="Plekha8"
                     /gene_synonym="6330400G01; Fapp-2; Fapp2"
                     /note="pleckstrin homology domain containing, family A
                     (phosphoinositide binding specific) member 8"
                     /db_xref="GeneID:231999"
                     /db_xref="MGI:MGI:2681164"
     exon            1..361
                     /gene="Plekha8"
                     /gene_synonym="6330400G01; Fapp-2; Fapp2"
                     /inference="alignment:Splign:2.1.0"
     CDS             322..1881
                     /gene="Plekha8"
                     /gene_synonym="6330400G01; Fapp-2; Fapp2"
                     /note="isoform 1 is encoded by transcript variant 1;
                     pleckstrin homology domain-containing family A member 8;
                     PH domain-containing family A member 8; phosphoinositol
                     4-phosphate adapter protein 2;
                     phosphatidylinositol-four-phosphate adapter protein 2"
                     /codon_start=1
                     /product="pleckstrin homology domain-containing family A
                     member 8 isoform 1"
                     /protein_id="NP_001157833.1"
                     /db_xref="CCDS:CCDS51781.1"
                     /db_xref="GeneID:231999"
                     /db_xref="MGI:MGI:2681164"
                     /translation="MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSI
                     QMAVCEIQVHSVDNTRMDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQK
                     EKEFAENTENLKTKMSELRLYCDLLVQQVDKTKEVATAGVTDSEEGIDVGTLLKSTCN
                     TFLKTLEECMQIANAAFTSELLYHTPPGSPQLAVLKSSKMKHPIIPIHNSLERSMELN
                     SCENGSLSIEVNGDEEILMKTKSSLYLKSTEVDCSISSEENTDDNVTVQGEIMKEDGE
                     ENLESHDKDPAQPGSDSVCSPESPWEDNEEVIPTFFSTMNTSFSDIELLEDSGIPTEA
                     FLASCYAVVPVLDKLGPTVFAPVKMDLVGNIKKVNQKYITNKEEFTTLQKIVLHEVEA
                     DVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKDIQTALNNAYGKTLRQHHGWVVR
                     GVFALALRAAPSYEDFVAALTIKEGDHQKEAFSAGMQRDLSLYLPAMEKQLAILDTLY
                     EIHGLESDEVV"
     exon            362..478
                     /gene="Plekha8"
                     /gene_synonym="6330400G01; Fapp-2; Fapp2"
                     /inference="alignment:Splign:2.1.0"
     exon            479..634
                     /gene="Plekha8"
                     /gene_synonym="6330400G01; Fapp-2; Fapp2"
                     /inference="alignment:Splign:2.1.0"
     exon            635..759
                     /gene="Plekha8"
                     /gene_synonym="6330400G01; Fapp-2; Fapp2"
                     /inference="alignment:Splign:2.1.0"
     exon            760..918
                     /gene="Plekha8"
                     /gene_synonym="6330400G01; Fapp-2; Fapp2"
                     /inference="alignment:Splign:2.1.0"
     exon            919..959
                     /gene="Plekha8"
                     /gene_synonym="6330400G01; Fapp-2; Fapp2"
                     /inference="alignment:Splign:2.1.0"
     exon            960..1117
                     /gene="Plekha8"
                     /gene_synonym="6330400G01; Fapp-2; Fapp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1118..1274
                     /gene="Plekha8"
                     /gene_synonym="6330400G01; Fapp-2; Fapp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1275..1360
                     /gene="Plekha8"
                     /gene_synonym="6330400G01; Fapp-2; Fapp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1361..1419
                     /gene="Plekha8"
                     /gene_synonym="6330400G01; Fapp-2; Fapp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1420..1550
                     /gene="Plekha8"
                     /gene_synonym="6330400G01; Fapp-2; Fapp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1551..1621
                     /gene="Plekha8"
                     /gene_synonym="6330400G01; Fapp-2; Fapp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1622..1683
                     /gene="Plekha8"
                     /gene_synonym="6330400G01; Fapp-2; Fapp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1684..6723
                     /gene="Plekha8"
                     /gene_synonym="6330400G01; Fapp-2; Fapp2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6693..6698
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Plekha8"
                     /gene_synonym="6330400G01; Fapp-2; Fapp2"
                     /note="hexamer: AATAAA"
     polyA_site      6723
                     /gene="Plekha8"
                     /gene_synonym="6330400G01; Fapp-2; Fapp2"
                     /note="major polyA site"
ORIGIN      
        1 aaaccctggc gtggatttgg tagcgtgcgc acagcgcagt gagcatgcgc gagcgcgccg
       61 gggcgggcgc tgtgggctca gtggccgcag gaaggcgccc gcgaccgccg ccacaggggc
      121 cgcgcctccc gcgcctccct cgcctctctc tggcggccgc tctgcggcgt ccacaccgac
      181 tgcgccaggc gcaggcgcag cccccgggac ccggagctgg tgctcccagg ctgtcgcggt
      241 gaccccgccc ccgggcccag gatgtgaggc cggcccggcg tccccgcggc gggccggggc
      301 gacgaggggc ccgcgggtgc catggagggc gtgctgtaca agtggaccaa ctacctgagc
      361 ggttggcagc ctcgatggtt ccttctctgt gggggaatac tgtcctatta cgactctcct
      421 gaggatgcct ggaagggttg caaagggagc atccagatgg cagtctgtga gattcaagtt
      481 cattccgtgg ataacactcg catggacctc atcatccccg gggaacagta tttctactta
      541 aaagccagga gtgtggcaga gagacagcgg tggctggtgg ctctgggatc tgccaaggcc
      601 tgcctgacag atagtaggac tcagaaggaa aaagaatttg cagaaaacac tgaaaacttg
      661 aaaaccaaaa tgtcggagct aagactgtac tgtgacctcc ttgttcaaca agtagataaa
      721 acaaaagaag tggccacagc cggtgtcact gactctgagg agggaattga tgtgggaacc
      781 ctgctaaaat cgacctgcaa cactttcctg aagaccttgg aagaatgcat gcagattgca
      841 aacgcagcct ttacctccga actgctttac catacacccc cagggtcccc tcaactagcg
      901 gtgcttaagt ccagcaagat gaaacatccc atcataccaa ttcataattc gttggaaagg
      961 tcgatggagt taaacagttg tgaaaatgga tcgctaagta tagaagtaaa tggtgatgaa
     1021 gaaatcctaa tgaaaaccaa gagttccttg tatttgaagt ccacagaggt ggattgcagc
     1081 atctccagtg aagaaaacac agatgacaat gtgacagtcc agggggagat aatgaaggaa
     1141 gatggcgagg aaaacctgga gagtcatgac aaggatccgg cacagcctgg atcagactcg
     1201 gtttgctcgc cagaatctcc ctgggaagac aatgaagaag ttattccaac tttcttcagt
     1261 actatgaata ccagctttag tgacattgaa cttctggagg acagtggcat tcccacagaa
     1321 gcattcttgg cctcctgtta tgcagtggtt ccagtcctag acaaacttgg tcccacagtg
     1381 tttgctcctg ttaagatgga tcttgttgga aatattaaga aggtaaatca gaagtacata
     1441 accaacaagg aagagtttac taccctccag aagatagtgc tgcatgaggt ggaggctgac
     1501 gtcgctcagg ttaggaactc ggcgacggaa gccctcttgt ggctgaagag aggtctcaaa
     1561 tttctaaagg gatttttgac agaagtgaag aatggagaaa aggatatcca gacagcactg
     1621 aataacgcat atggcaaaac attacggcaa caccatggct gggtagttcg aggggtcttt
     1681 gcgttagcac tgagggcagc gccatcctat gaggactttg tagctgcgct aaccataaaa
     1741 gaaggcgacc accagaaaga agctttcagt gctggcatgc agagggacct cagcctttac
     1801 ctccccgcta tggaaaagca gctggccata ctggacacgt tatatgagat ccacgggctg
     1861 gaatctgatg aggtggtgtg acagccacag gacagcacct cctaacttca gggaataaag
     1921 tctgctaaag tgttgtgttg ccctagttaa tttccagcaa cagctttgat actctccagc
     1981 ctttccttgg ggagatggac atgaggaagt cctagtgctt ttatttagaa ttgttttaat
     2041 gcatatgtgt ttcatgtgtt taaaaatcaa ggtgctaaat atttcaacag gcctactgga
     2101 aaccagatca tcgctgtccc agacttgaat agcaggcagt aagagcaaaa ttgacagatg
     2161 gatttgttgg gttcacattt gtattgttct gtttcagtta ctagttttaa tgggccaccc
     2221 aaaccgaagc agtatgcagg actattgtat aaagccagtg tttaaaatag cttagatgtt
     2281 gactgggcat tggagggagt gtaagcccct ttgttgaagg acttgctgtg taagagtttg
     2341 ctattcctac actttcctga gtggatcctt tctcccttcc tctgctgatg gaaagggctg
     2401 tgtagtgaaa acatttgggc agttgtagga aaacattgac atggactgcc atgcctgttg
     2461 tcaggtggga cagtggctca agagaatgac ctcagcccat gcttgagaac agaatagaca
     2521 ggaaggataa gtcatttggg tgacacatac cactctttgc caatgcagta catttcctat
     2581 gtgttatctg aattgaacat catagcagaa cagcgacttt aaagaggata tttaatccta
     2641 cttcacaagt aaagcttaca gtagggaggt ctgctcacat ttgtggaatt tcttgtttct
     2701 ggtgatttta tttttattta ttgatttatt tattttgcct gtttcattaa ctcttcagca
     2761 aaagagccag gtagcttcca aatgtgatct agatcacctc tgtattgaag tcacatgaca
     2821 tgctgtttca aagaacagag tcctaggaca tgcctgaaga acccagatct tacaaggctg
     2881 aagagccaaa ttcccatttg aattctagtt tacagaattc ccagtcttct gcagaaacca
     2941 aataaaacac ctccttccag agaaaggggc cgccattcaa gtaacataat taaatggaga
     3001 gtgagtagac cagcagctgg tgtaacagct tgaggcattc ttctataaag agtgacaaga
     3061 tgccctgtct cccagaaatg gaccaagctg cctagagtgt gcatagggaa gaagccatga
     3121 ataccttccc aagtggaggc cacttcttcc tagcaacaag aagagtggct ccagcataag
     3181 cagtcccctg aagacaacga gccttggcca ggcacaggtg agggagtggc tgtgcacact
     3241 gcttctgttg ctgtgcacac tagggctctg cagagaacta tgcagggaag gtactgattt
     3301 tgtctgtctt taaacgagtg ggtatttact caatgcagca gtagagtggg ccacggcggt
     3361 acctgcagtc cagctaccca gaagtatgag agtaaagtat tatttgagcc caagatttgg
     3421 agattaacct gaacaacata gcaagacctt gcctcttaaa aacacttgta ataaaatttt
     3481 aagccaagca agcattttgc caacataaga agttctagaa attaaactta ggaaagggag
     3541 gagtgggctg gacttacagt atgctacttt cctcttgcag gagtttcata tggatcctct
     3601 tctctggcta atggaaaggg gtcagggcta aggcataact tagacctgcc cttgacatag
     3661 cctgtaaaga cagaagaaga aaagtggcca gcccgcttgt ctctgagggt gggcgctttg
     3721 ggccatgtgc ccttggtggg ctctgctacc aggaaattga cgttaagtat ggccatgata
     3781 ggcagctgca ggtgcctctg tgatctctag tctagggact agcactctga gagcgtgtca
     3841 gtccaggtcc tcacaaagcc ctaagtgccc actggagagc tgccttgctg ggcagtctga
     3901 ctttggtacg ttcattccac ctgaattagt agttcttggt gtctcattgt agttaaagct
     3961 aatttttttt gtctgatttt tcagttactt tctaagaaat gaaaaaaaag aacctgaaag
     4021 tgctccctgg agcccctccc gagagccctg gtatttctaa gccaccctca ccctgacaga
     4081 tgaagaaccg gtttgttggt tgacagaatg cttaccttct ctttgttgct aacagttttt
     4141 ggattatctt cctagcataa tcttgagagt gggggatgtg tcttgctaga gagcagtaga
     4201 gttgactgag tagtactggc agaccactca cagagcacag ccccacctcc gttccatcag
     4261 tctgcccttc accctcaccc agtgaagctt ggctccccac gggctgatgt cagtatgtgt
     4321 gttgaactga acagaggctt tttaattgtg ataagcctta tgtcttttga agataggtct
     4381 gtttatagcg aaaacctact gacatatgct gatttgtcag gaggaatatc tttaagggaa
     4441 gaaaccatct tgtaactgag gcagagctga cagctcttga cacagcccag aagagaggcc
     4501 agaagggtac tgtaggaatg tagtggcttg ttactatgtc cagatcattc taagcgtaag
     4561 agcatccccc agtgtcactt aaccatcgtg gggacatccg cacgccctct ctcagctttt
     4621 ctcttctctg ctgccaagca ttgccagcag tgaccccgcc cccatcagct tgccacagtg
     4681 attttccctc ccagctcgtt tccccttctt cagcagcagc agcagcagcc tacctggtcc
     4741 aggatctatt ctatacctag ccaaaacgcc agggcttcag gcagaagcca tgttcacatt
     4801 tgtagctgtt aggttgggga aagtcagcgt gggagagcat gtcctccgat tgcgtacagt
     4861 cagtgccgtc aacgtctgtc tgtggagggt tttcaggtgc aggtgtatgg tgaggtcata
     4921 agtacagggc actttagctg aagaactcta aagaaaacga atccagctgt aaagatatat
     4981 atgaaacttt ttttaaaatg tattccctac tagaccacta tgtccttcag gcacagggct
     5041 atgtcatgtt gtgtttcttt tttttttttt tcctttttcc aattttttat tagttatttt
     5101 cttcatttac atttcaaatg ctatcctgaa cagttcaaac cacagcttct gatttagtca
     5161 caagtttacg atggttcaaa tccctaccct catggttcat ttcactacca gtcgtttgta
     5221 aattctaagc tgtctggatg tagaagttct gagcaactgc agtatgtttt ggaccatcac
     5281 tttggttgat catctaacgc atttgggcgt agagagccaa acctaggatg ctttgtgata
     5341 ctgtgcagtc tgcatggttg tgtgcattag accctcctgt gacatgcaca tgaagtgctg
     5401 tgttgacaaa tgtgttctac ttccatgtga ccctttgtaa cctgcagtag cttactcaga
     5461 gttacacaat aatgacataa ctattcacta gctgcccaat ggcatttgaa gatttaagcc
     5521 atgacaaggt tatagatata gtacattagt tgagggccct tccctccctg tggattctcc
     5581 tcttctagcc ctgtctagac tatcctgcag accatttgca tgatttcttg ctgtacagct
     5641 gcatttggga actctaaggc atgaacaccc agtcactggc aatgcctctg gtacagatgt
     5701 cgctcgcatg cattgatctc tcttctccat tgtctataga tagatagcct ttaatggaaa
     5761 ggaaaaaaat gccactgctc tgcaatgcaa agttttcaga attcttgtaa atcgtgaatc
     5821 cttgtgtcac ttctttaggg tgaaaaatgt ttctagtcaa gctgtatggg aacatcctgc
     5881 ttattttaaa tgtcttatat atttaaagta tggtcagtat tatcccttta cacatacctt
     5941 gggcaaggtg gtcccctcag ccttaggatg gatggcttca tggcacagcc gatctcattc
     6001 acagagagcc cggtgtatgt ccattcagat gtgtagatgg ggccagtgaa gggtgatcta
     6061 gatggctgat gagccagctt catggtgtag ggtaacggac gattccctgt gccatgagaa
     6121 tttcactaga atgtcactaa acagcccaac tacctcatgt gaaattggct gtggacaatc
     6181 tgtgtttgat gagaaatgtg ttcgcagaaa tttattctgt ttgataagtt gaacagtgca
     6241 gtgtctctat gaagaagaaa catgttatac cagatgccaa aggctaaact agacatagat
     6301 ttctcagatt catttctatg ttaatgttta ttccagtctg tatcctcata aaggtttgta
     6361 gttttgtaga gccacatgct ttgggtatct gtcacaatca cctcttgtcc cctcagtatt
     6421 ttgactgaac atcataatgc tgataggaat caagttaaac tacgaaagtg tcaaacagct
     6481 tgtggcttct taatttaatg gacctttact tagaaatgta ttggagcctt ctaggaccac
     6541 ttgttgagtg aaaatcttgt gtgcagatgt gtctgcttct ctgtccaagt tgttgttcct
     6601 gtatttcatg aaaagtgggg caggggtgag ggttttactt tctttggaga atgtttgaaa
     6661 acatctgtca gatttttata ttcattagtt acaataaaca tatttttaga gtattttatt
     6721 aaa
//
