LOCUS       NM_144920               5133 bp    mRNA    linear   ROD 12-NOV-2024
DEFINITION  Mus musculus pleckstrin homology domain containing, family A member
            5 (Plekha5), mRNA.
ACCESSION   NM_144920
VERSION     NM_144920.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5133)
  AUTHORS   Leon,N.Y., Le,T.N.U., Garvie,A., Wong,L.H., Bagheri-Fam,S. and
            Harley,V.R.
  TITLE     Y chromosome damage underlies testicular abnormalities in ATR-X
            syndrome
  JOURNAL   iScience 27 (5), 109629 (2024)
   PUBMED   38616920
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5133)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 5133)
  AUTHORS   Ming,Z., Bagheri-Fam,S., Frost,E.R., Ryan,J.M. and Harley,V.R.
  TITLE     A role for TRPC3 in mammalian testis development
  JOURNAL   Front Cell Dev Biol 12, 1337714 (2024)
   PUBMED   38425503
  REMARK    Erratum:[Front Cell Dev Biol. 2024 Oct 15;12:1484634. doi:
            10.3389/fcell.2024.1484634. PMID: 39474354]
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5133)
  AUTHORS   Souali-Crespo,S., Condrea,D., Vernet,N., Feret,B., Klopfenstein,M.,
            Grandgirard,E., Alunni,V., Cerciat,M., Jung,M., Mayere,C., Nef,S.,
            Mark,M., Chalmel,F. and Ghyselinck,N.B.
  TITLE     Loss of NR5A1 in mouse Sertoli cells after sex determination
            changes cellular identity and induces cell death by anoikis
  JOURNAL   Development 150 (24) (2023)
   PUBMED   38078651
REFERENCE   5  (bases 1 to 5133)
  AUTHORS   Yao,Y., Shi,B., Zhang,X., Wang,X., Li,S., Yao,Y., Guo,Y., Chen,D.,
            Wang,B., Yuan,Y., Sha,J. and Guo,X.
  TITLE     Germ cell-specific deletion of Pex3 reveals essential roles of
            PEX3-dependent peroxisomes in spermiogenesis
  JOURNAL   J Biomed Res 38 (1), 24-36 (2023)
   PUBMED   38062668
REFERENCE   6  (bases 1 to 5133)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   7  (bases 1 to 5133)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   8  (bases 1 to 5133)
  AUTHORS   Lecureuil,C., Fontaine,I., Crepieux,P. and Guillou,F.
  TITLE     Sertoli and granulosa cell-specific Cre recombinase activity in
            transgenic mice
  JOURNAL   Genesis 33 (3), 114-118 (2002)
   PUBMED   12124943
REFERENCE   9  (bases 1 to 5133)
  AUTHORS   Wertz,K. and Herrmann,B.G.
  TITLE     Large-scale screen for genes involved in gonad development
  JOURNAL   Mech Dev 98 (1-2), 51-70 (2000)
   PUBMED   11044607
REFERENCE   10 (bases 1 to 5133)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ170110.1 and AK129423.1.
            
            On Jul 29, 2006 this sequence version replaced NM_144920.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN01164131,
                              SAMN01164132 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-258               CJ170110.1         50-307
            259-5133            AK129423.1         1-4875
FEATURES             Location/Qualifiers
     source          1..5133
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 70.34 cM"
     gene            1..5133
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /note="pleckstrin homology domain containing, family A
                     member 5"
                     /db_xref="GeneID:109135"
                     /db_xref="MGI:MGI:1923802"
     exon            1..158
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..3876
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /note="phosphoinositol 3-phosphate-binding protein-2;
                     Gt(Ayu21)9Imeg"
                     /codon_start=1
                     /product="pleckstrin homology domain-containing family A
                     member 5"
                     /protein_id="NP_659169.3"
                     /db_xref="CCDS:CCDS39688.1"
                     /db_xref="GeneID:109135"
                     /db_xref="MGI:MGI:1923802"
                     /translation="MAADLNLEWICSLPRSWTYGITRGGRVFFINEEAKSTTWLHPVT
                     GEAVVTGHRRQSTDLPTGWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVV
                     NDQTVATMTSEDKKERPISMINEASNYNMASDYAVHPMSPVGRTSRASKKVHNFGKRS
                     NSIKRNPNAPVVRRGWLYKQDSTGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLP
                     SFQIAMLTAEDHINRKYAFKAAHPNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVK
                     RITFNFRVDKITTDSASTKETNNIPNHRVLIRPEVQNHQKNKEISKIEEKRALEAERY
                     GFQKDGQDRPLTKINSVKLNSLLSEYESGPDCPPQNVHYRPINVNSSDGKAVNVSLAD
                     VRGGSHPNAGPLATEADRVIQRTNSMQQLEQWIKVQKGRGLEEEPRGVISYQTLPRNM
                     PSHRAQILARCPEGYRTLPRNSKTRPESICSVTSSGHEKTGPGAEEKRRSMRDDTMWQ
                     LYEWQQRQFYHKQSTLPRHGCLSSPKAMVQVSDQTMHSIPTSPSHGSAAAYQGFSPQR
                     TYRSEVTSPIQRGDVTIDRRHRPHHPKHVYVADRRSMPAGLTLQAVSPQSLQGRTPEE
                     LTLLLIKLRRQQAELSSVREHTLAQLMQLKLEAHSPKNEILSHHLQRNTIYLDHQMKE
                     NEPIITMVHTMIENSALRPQLYQQFLRQKNKISLYCLSQDECRGTLYKYRPEEAGIDA
                     KLSRLCEQDKVVRALEEKLQQLHKEKYTLEQALLSASQEIEMNADNPAAIQTVVLQRD
                     DLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRDQMQGQLDRLGEVQSESAGI
                     QRAQIQKELWRIQDVMEGLSKHKQQRGSSETGLAGSKPFSSVKYKSEEEEVVPPRPPL
                     PRSYDFTEQPPIIPPLPSDSSSLLCYSRGPVHLPEDKKIHQVQGYPRNGSHCGPDYRL
                     YKSEPELTTVAEVDESNGEEKSEPVSETEAPVVKGSHFPVGVPLRTKSPTPESSTIAS
                     YVTLRKTKKMVELRTERPRSAVEQLCLAESARPRMTVEEQLERIRRHQQACLREKKKG
                     LSVLGASDPSDVRDSPLRLTQTLRRDDNVKELDTVHRENDVKPDYETPAAQCAHLEDA
                     EPQNADIGRKLKRSEMLYTPEPNGMASEEVTEKERQKEQVHADGSCSPQEETAMTEHQ
                     MEGPPEEAESLHEEEETLASCEPAPEIPRENQTTVRSLSPSPDSSTAADPPTPPQLRE
                     GSHFMCV"
     exon            159..238
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            239..296
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            297..380
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            381..501
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            502..606
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            607..679
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            680..780
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            781..896
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            897..914
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            915..1382
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            1383..1845
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            1846..1929
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            1930..2049
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            2050..2103
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            2104..2184
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            2185..2220
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            2221..2283
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            2284..2364
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            2365..2514
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            2515..2616
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            2617..2728
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            2729..2775
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            2776..2964
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            2965..3085
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            3086..3201
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            3202..3393
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            3394..3534
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            3535..3644
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            3645..3781
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     exon            3782..5133
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4619..4624
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /note="hexamer: AGTAAA"
     polyA_site      4640
                     /gene="Plekha5"
                     /gene_synonym="2810431N21Rik; AMH-Cre; Ayu21-9;
                     Gt(pU21)9Imeg; Pepp2; Tg(AMH-cre)1Flor"
                     /note="major polyA site"
ORIGIN      
        1 tcgcgccctc cttcctcagc ggcggcggca gcacaaggcg gcggcggcgg cggccgggga
       61 gcagacatgg cggccgacct gaacctggag tggatctgct cgctgccgcg ctcctggacg
      121 tacgggatca ctaggggcgg ccgcgtcttc ttcatcaacg aggaggccaa gagcaccacc
      181 tggctacacc cggtcaccgg cgaggccgtg gtcaccgggc accggcggca gagcacagat
      241 ttgcccactg gctgggaaga agcatatacg ttcgaaggtg caagatacta tataaaccac
      301 aatgaaagga aagtgacctg caagcatccg gttacaggac agccatccca agacaactgt
      361 atctttgttg tgaatgatca gactgttgca accatgacgt ccgaagacaa gaaggaacga
      421 cccataagta tgataaatga agcttccaat tacaacatgg cttcagatta tgcagtgcat
      481 cccatgagcc ctgtgggcag gacctcgcgg gcctccaaaa aggttcataa ttttgggaaa
      541 aggtccaatt caattaaaag gaaccctaat gcacctgtgg tccggcgtgg ctggctgtat
      601 aagcaggaca gcaccggcat gaagctgtgg aagaagcgct ggtttgtgct ctctgacctt
      661 tgccttttct attaccgaga tgagaaggag gagggtattt tgggaagtat cctgttgcct
      721 agttttcaga tagccatgct cactgctgag gaccacatca atcgcaaata tgcttttaag
      781 gcagcccacc caaacatgcg gacctattat ttctgcaccg atacaggaaa ggagatggag
      841 ctgtggatga aggccatgtt agatgctgct ctggtgcaga cagaacctgt gaaaagaatt
      901 acctttaatt tccgagtgga caagattaca actgacagtg catcaaccaa agaaaccaat
      961 aacattccca accacagagt tctcattaga cccgaggtcc aaaaccatca gaagaataag
     1021 gaaatcagca aaattgaaga aaaaagggcc ttagaagctg aaagatacgg atttcagaag
     1081 gacgggcaag atagaccatt aacaaaaatt aacagtgtga agttgaactc cctgctatca
     1141 gaatatgaaa gcgggccaga ctgcccacct cagaatgtac actacagacc catcaatgtg
     1201 aatagttctg acggcaaagc ggtgaatgtc agcttggcag atgtccgggg tgggagtcac
     1261 ccaaatgcag ggcccctagc cacagaggcc gaccgagtca ttcagagaac gaattcaatg
     1321 caacagctag agcagtggat taaagtccag aaaggacggg gtcttgaaga agagcccaga
     1381 ggagtaattt cttatcaaac attgccaaga aatatgccaa gccacagagc ccagatcctg
     1441 gcccgctgcc ctgaaggtta ccggacactc ccgagaaaca gcaagaccag acctgagagt
     1501 atctgcagcg taacctcttc tggtcatgag aagacagggc cgggagcaga agagaagcgg
     1561 cgatccatga gagatgacac catgtggcag ctgtacgagt ggcagcagcg ccagttttac
     1621 cacaagcaga gcaccctccc tcggcacggc tgcctgagca gtcccaaagc catggtgcag
     1681 gtgtctgacc agacgatgca ctccatcccc acgtcacctt cccatgggtc agcagctgct
     1741 taccagggct tctcccctca gcggacgtac aggtcagaag tgacctcgcc catccagaga
     1801 ggagatgtga cgatagaccg caggcacagg cctcatcacc ctaagcatgt ctatgtagct
     1861 gacagaaggt caatgccagc tggcttaact ttacaggctg ttagtcccca gagcctccaa
     1921 ggcagaacgc cagaggagct cacactgctg ctaataaagc tgagacggca gcaggcagag
     1981 ctgagtagtg tccgggagca caccttagca cagctcatgc agctgaaact tgaggcccac
     2041 agcccaaaga atgagattct ttcacatcat ctccaaagga acaccatata tttggatcat
     2101 cagatgaaag aaaatgaacc tattatcacc atggttcaca caatgattga gaactcggcg
     2161 ctaagaccac aactgtacca acaattctta agacagaaga acaagataag tctctattgt
     2221 ctgtcacaag atgaatgtag aggcacatta tacaaataca gacctgaaga agcaggtatt
     2281 gatgccaaat taagcagatt gtgtgaacag gataaagtgg tccgagcgct ggaggagaag
     2341 ctgcagcagc tgcacaagga gaaatacacg cttgagcaag ccttgctgtc agccagccaa
     2401 gagatagaga tgaatgctga taacccagct gccattcaaa ctgtggtgtt gcagagggat
     2461 gacctgcaaa acggactgct gagcacgtgt cgggaactct cccgagccac tgctgagctg
     2521 gaacgagcct ggagagaata tgacaagttg gaatatgatg tgactgttac cagggaccag
     2581 atgcagggtc agctcgaccg ccttggagaa gtgcagagtg agtcggcagg aattcaacgg
     2641 gcacagattc aaaaggagct ctggagaatt caagatgtca tggaggggtt gagcaaacac
     2701 aaacagcaaa gaggctcttc agaaacaggt ctggcaggat caaagccttt ctcatcagtt
     2761 aagtacaaga gcgaggaaga ggaagtagtc ccacctcggc ctccacttcc tcggtcttat
     2821 gactttacag agcagcctcc cataatcccc cctctgccca gtgatagcag ctccttgctc
     2881 tgttatagca ggggccccgt gcatctgcct gaagacaaga agattcatca agttcaagga
     2941 tatccaagaa atggatctca ctgtggtcca gattatagac tctacaagag tgagccagag
     3001 ttaaccacag tggcagaagt cgatgaatct aacggagaag aaaagtcaga gccagtttct
     3061 gagacagaag ctccagtcgt taaaggttcc cattttccag tcggagttcc tctgagaaca
     3121 aagtcaccca cacccgagtc ctccacgata gcttcctatg tgaccttgag gaagactaag
     3181 aagatggtgg agctaagaac ggaaagacca agaagtgccg tggagcagct gtgtctggct
     3241 gagagtgctc gacctagaat gactgtggaa gagcagctag agaggatcag gagacaccag
     3301 caggcctgcc tgagggagaa gaagaagggg ctgagtgtcc tcggtgcttc cgacccgtca
     3361 gacgtgaggg acagtccact caggcttact cagactctaa ggagggatga taacgttaag
     3421 gagctagaca ccgtccacag agaaaatgat gtaaagccag actacgagac tccagcagca
     3481 cagtgtgctc acctagaaga cgctgaaccc cagaatgcag acatcggcag aaagctaaaa
     3541 agatctgaaa tgctttacac acctgaacca aatggaatgg cttctgagga agtgacggag
     3601 aaggaaagac agaaagagca ggtgcatgcc gatgggtcat gcagccctca ggaagagacg
     3661 gccatgacag agcatcagat ggaaggcccc cctgaggaag cagagagtct tcatgaggag
     3721 gaagaaactc ttgcttcctg tgagccagct cctgagattc ctagggagaa tcaaaccaca
     3781 gtgagaagtc tgtccccgtc tcctgactcc tccacggcag cagatccgcc cactcctcca
     3841 cagctcaggg aaggatcgca tttcatgtgt gtgtagtcgc agaagtacgt cttctcttcc
     3901 ctttggtact ttgtgttagg agtatgttac ttggattcta tccatttgtt ggaacagcaa
     3961 tacaagcaaa ttaaccctgg actatgtccc accagagcac ctggccatgt atgtgaagtc
     4021 caggccgtag ttcaggtttc tcatattgcc ctggcaggga gtgggtctct ggtggcattt
     4081 tctctcagtc tgtcatagca tcatccacac gtgcagcaga atctgcagtg agcggcctgt
     4141 gccagccctc ctggcagcgc tgcagctgtg ccctggagac atcctgccca cactcaggct
     4201 gaggagccag ggctgccctt tggacaaagc catgattatg atgtagtctg gggcggaggc
     4261 ttgacatttc gaaaccgttg ggttggagcc aggatagagc gagctgaggg tgacttcctt
     4321 cattgcttct ttggggcttt tttattatta ttactgttcc caatagtaat gtgtgtactg
     4381 tatatctaat gtgtatgtgt gatggatatg ccacatgagt gtgccatgac aagagtgtga
     4441 aggccaaagg acagctttgt ggatccagtt ctgtcctgcc cctatgtcca ttctgaggtt
     4501 tgaacttgag ttatcagtga gggcataggc actgctaaac tgtctcactg tccctcacac
     4561 acaccagact ccacactgtg tgcacagaac ctcccttact cagaaatttg tgcttacaag
     4621 taaatcgttt tcctggaaaa tgggagtgag aatctatacg ccgtttctat atgttttctc
     4681 agcatccact gcctcttaca atgctgggag cttttgagtt cctataaact ccagagtagc
     4741 cctggagtaa cagcagcatg agctgtcagg caggcagtct tcaggtgtcc ccagccggcc
     4801 gcacagcggc ctctcacctg ggctctgcct tcaccctgtc ttggcctttg tagtagctct
     4861 gcgctttgac tcgaagctcc tgtggttgtg ggttggcttc cgtgctgggt tgaggagctt
     4921 cgctagagtt aggaatgacc agttgtgcca ccacgcccag cctcatatgt ttttttaaaa
     4981 aagttatttt tgtgccttta aaaaatgact taattgataa tagatcatgc agggcagggc
     5041 gccttctttc tgggtcaggt tcactgctcc ctgctttcag tagcagaggg tgtctgttat
     5101 ccagagcagg ccagtacaat aaacagaaaa tgg
//
