LOCUS       NM_001381849            3083 bp    mRNA    linear   ROD 09-JUN-2024
DEFINITION  Mus musculus pleckstrin homology domain containing, family A
            (phosphoinositide binding specific) member 4 (Plekha4), transcript
            variant 1, mRNA.
ACCESSION   NM_001381849 XM_006541162
VERSION     NM_001381849.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3083)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 3083)
  AUTHORS   Magdaleno,S., Jensen,P., Brumwell,C.L., Seal,A., Lehman,K.,
            Asbury,A., Cheung,T., Cornelius,T., Batten,D.M., Eden,C.,
            Norland,S.M., Rice,D.S., Dosooye,N., Shakya,S., Mehta,P. and
            Curran,T.
  TITLE     BGEM: an in situ hybridization database of gene expression in the
            embryonic and adult mouse nervous system
  JOURNAL   PLoS Biol 4 (4), e86 (2006)
   PUBMED   16602821
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC151602.4.
            
            On Apr 15, 2020 this sequence version replaced XM_006541162.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.1467519.1,
                                           SRR11927936.2496935.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-535               AC151602.4         60331-60865         c
            536-625             AC151602.4         59806-59895         c
            626-733             AC151602.4         58099-58206         c
            734-806             AC151602.4         56054-56126         c
            807-907             AC151602.4         55857-55957         c
            908-1017            AC151602.4         55611-55720         c
            1018-1233           AC151602.4         52592-52807         c
            1234-1513           AC151602.4         51987-52266         c
            1514-1597           AC151602.4         51175-51258         c
            1598-1645           AC151602.4         49937-49984         c
            1646-1726           AC151602.4         49553-49633         c
            1727-1876           AC151602.4         49260-49409         c
            1877-1975           AC151602.4         46420-46518         c
            1976-2116           AC151602.4         42374-42514         c
            2117-2216           AC151602.4         41305-41404         c
            2217-2293           AC151602.4         41158-41234         c
            2294-2455           AC151602.4         40499-40660         c
            2456-2505           AC151602.4         37170-37219         c
            2506-2618           AC151602.4         36783-36895         c
            2619-3083           AC151602.4         36235-36699         c
FEATURES             Location/Qualifiers
     source          1..3083
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 29.34 cM"
     gene            1..3083
                     /gene="Plekha4"
                     /gene_synonym="2410005C22Rik; Pepp1"
                     /note="pleckstrin homology domain containing, family A
                     (phosphoinositide binding specific) member 4"
                     /db_xref="GeneID:69217"
                     /db_xref="MGI:MGI:1916467"
     exon            1..535
                     /gene="Plekha4"
                     /gene_synonym="2410005C22Rik; Pepp1"
                     /inference="alignment:Splign:2.1.0"
     exon            536..625
                     /gene="Plekha4"
                     /gene_synonym="2410005C22Rik; Pepp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             542..2881
                     /gene="Plekha4"
                     /gene_synonym="2410005C22Rik; Pepp1"
                     /note="pleckstrin homology domain-containing, family A
                     member 4; phosphoinositol 3-phosphate binding protein-1;
                     PEPP-1; PH domain-containing family A member 4"
                     /codon_start=1
                     /product="pleckstrin homology domain-containing family A
                     member 4"
                     /protein_id="NP_001368778.1"
                     /db_xref="GeneID:69217"
                     /db_xref="MGI:MGI:1916467"
                     /translation="MEQGRPRSSLSLASSASTVSSLSSLSTKKPTRAVHKVHAFGKRN
                     NALRRDPNLPVHIRGWLHKQDSSGLRLWKRRWFVLSGHCLFYYKDSREESVLGSVLLP
                     SYSVRPDGPGAPRGRRFTFTAEHPGMRTYVLAADTLEDLRGWLRALGRASRAEGEDCG
                     LPRSPARPRPGEGPGGPGGPPEVNRREEGRISESPEVARLSRGLGRHETHTPNSTVDL
                     QTDTWSRRTRSPELFSPLSRPPSPLSLPRPRSAPARRPPLSAGDISFPARPHTPLSRI
                     DVRPPLDWGPQRQTLSRPPIPRRGPSSEAGGERPPRSPQPRTPEQRTQSTQATSGSST
                     YLQLPPRPPGTQASMILLPGPPVDSALHQSLETDTLLTKLCGQDRLLRQLQEDLDKRQ
                     EEKEQLEAALELTRQQLGQATREAAASGKAWGRQRLLQDRLVNVRAALCHLAQERERV
                     WDTYSGLEQDLGTLRETLEYLLHLGSPQDRACAQQQLWMVEDTLAGLGGPQKQPPHTD
                     PKSPSPAPQGEESSERESLSESLELSSPQSPEVDWSRPSGGDRALSSPQSGVGSPRVS
                     RASSPECRQPSSPLLRTKAPLARPRMSAQEQLERMRRNQACGLPLPRPTSPRLLTLGR
                     TLSPAPRQPDMEQRPIVGAAKWLRSSGSWSSPRHSATCSPVPGGHRERVLSLSQALAT
                     EASQWHRLMAASPGRNLDTRGDCLQPSPQPPSEELPQVTSSPAPHKATSATTGFSCQG
                     SRRGLAPWEARWDPGKAPPALTQEEGAWPFRVTLLQSSF"
     exon            626..733
                     /gene="Plekha4"
                     /gene_synonym="2410005C22Rik; Pepp1"
                     /inference="alignment:Splign:2.1.0"
     exon            734..806
                     /gene="Plekha4"
                     /gene_synonym="2410005C22Rik; Pepp1"
                     /inference="alignment:Splign:2.1.0"
     exon            807..907
                     /gene="Plekha4"
                     /gene_synonym="2410005C22Rik; Pepp1"
                     /inference="alignment:Splign:2.1.0"
     exon            908..1017
                     /gene="Plekha4"
                     /gene_synonym="2410005C22Rik; Pepp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1018..1233
                     /gene="Plekha4"
                     /gene_synonym="2410005C22Rik; Pepp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1234..1513
                     /gene="Plekha4"
                     /gene_synonym="2410005C22Rik; Pepp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1514..1597
                     /gene="Plekha4"
                     /gene_synonym="2410005C22Rik; Pepp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1598..1645
                     /gene="Plekha4"
                     /gene_synonym="2410005C22Rik; Pepp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1646..1726
                     /gene="Plekha4"
                     /gene_synonym="2410005C22Rik; Pepp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1727..1876
                     /gene="Plekha4"
                     /gene_synonym="2410005C22Rik; Pepp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1877..1975
                     /gene="Plekha4"
                     /gene_synonym="2410005C22Rik; Pepp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1976..2116
                     /gene="Plekha4"
                     /gene_synonym="2410005C22Rik; Pepp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2117..2216
                     /gene="Plekha4"
                     /gene_synonym="2410005C22Rik; Pepp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2217..2293
                     /gene="Plekha4"
                     /gene_synonym="2410005C22Rik; Pepp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2294..2455
                     /gene="Plekha4"
                     /gene_synonym="2410005C22Rik; Pepp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2456..2505
                     /gene="Plekha4"
                     /gene_synonym="2410005C22Rik; Pepp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2506..2618
                     /gene="Plekha4"
                     /gene_synonym="2410005C22Rik; Pepp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2619..3083
                     /gene="Plekha4"
                     /gene_synonym="2410005C22Rik; Pepp1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3062..3067
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Plekha4"
                     /gene_synonym="2410005C22Rik; Pepp1"
                     /note="hexamer: AATAAA"
     polyA_site      3083
                     /gene="Plekha4"
                     /gene_synonym="2410005C22Rik; Pepp1"
                     /note="major polyA site"
ORIGIN      
        1 gccagagaga gggagagccc agcagagagg aaagagaaac tgggagaggg aggaagagaa
       61 aaagtgagga agagaacttg aaaaggaaag gaaacagatg tgtctggtca gggagacaga
      121 ggaagagact agagtgtgga aagcggaagt agaagagtgg aatgaagtgg ggagggggca
      181 ggggaagtga ttagacagca gcagcaaggt agggagaggg actgggagag gtgacatagg
      241 caggggtgga ggagaggggt agagagagag agagggagag agacagagag acacaggggg
      301 gagacagaga gacaccgaga gagacagggg tgggggggga gagggagaga gacagagaca
      361 cagagagaga cagacacaga gatagacaga gatgcagggg agagacagag agagggagag
      421 aaagaactca caagtgagac agagaagaaa gcagatatca ggtgaagagg gagaccattc
      481 tgagaggcac aaaaagaggt ggtgacagat cctgtcacca ggacaccaga actggttctc
      541 catggagcag ggccgacccc ggagcagcct cagcctggcc agcagtgctt ccaccgtctc
      601 ctctctgagt agcctgagca ccaagaagcc tacccgtgca gtacacaagg tccatgcctt
      661 tggaaaaagg aacaatgcac ttcgacgaga ccccaacttg ccggtgcaca tccgtggctg
      721 gctgcacaaa caggacagct caggcctccg gctgtggaag cgccgttggt tcgtcctttc
      781 aggccattgc ctcttctact ataaggatag cagagaagag agtgtcctgg gcagtgtatt
      841 attacccagc tacagtgtca ggccagatgg gcccggagcc cctcgtggcc ggcgattcac
      901 cttcacagca gagcacccgg gcatgaggac ctatgtcctt gcagctgaca cattagagga
      961 cctgagaggt tggcttcgag cactggggag ggcctctcgt gcggaggggg aagattgcgg
     1021 actcccgagg tcacctgcac gtcccaggcc tggggaaggt cctgggggac ccggaggacc
     1081 cccagaggtg aacagaaggg aagaggggcg catctcagaa tcaccagagg tagctcggct
     1141 ctccagaggt cttggcagac atgaaacgca cactcccaac tctacagtgg atctgcagac
     1201 tgacacctgg agtcgtagaa cccggagccc agagttgttc tcaccccttt cccggcctcc
     1261 ctcccctctg agccttcccc gtcctcgctc tgccccggcc cggcgacccc ctctctcagc
     1321 aggagacatc tcatttcctg cccgaccgca tactcctttg agtcgcatcg atgtccgacc
     1381 tcctctggat tggggacccc aaagacagac cctctcccga cctcccattc cacgccgagg
     1441 accttcctct gaagctggcg gagaacggcc acccaggagt ccccagcccc ggacaccaga
     1501 gcagagaacg cagtctaccc aggccacctc tggttcgtcc acctatctcc agctgccccc
     1561 aagacctcct gggacccagg cctccatgat tttgctgcca ggaccccctg tggactcagc
     1621 tttgcatcag agcttggaga cagatacgtt gttgactaag ctgtgtgggc aggaccggct
     1681 cctgaggcag ctacaggagg atctggacaa gaggcaggag gagaaggagc agctggaggc
     1741 agctttggag ctgacccggc agcagctggg ccaagctacc agggaggctg cagcttccgg
     1801 gaaggcctgg ggtcgccagc gccttctgca ggaccggctg gtgaacgtga gggctgctct
     1861 gtgtcacctg gctcaggagc gagagcgagt ttgggacaca tacagcggcc tggagcagga
     1921 cctcggcacc ctaagagaga cgctcgagta cctgctgcac ctcgggtctc cccaggaccg
     1981 tgcgtgtgct caacagcagc tgtggatggt ggaggacacg ctggcaggtc tgggtggccc
     2041 ccagaaacag cccccacata ctgatcccaa gtctccatcc cctgcacccc aaggagaaga
     2101 gtcctcagag agggagagcc tttcagagtc actggagctc agctcccctc agtcccctga
     2161 ggtggactgg agtcgtccct caggcggtga cagagccctc agcagccctc agtcaggtgt
     2221 tgggtctcca agggtctccc gggcatccag ccctgaatgt cgtcaaccct catctccact
     2281 gctgagaact aaggccccgc tggcgcggcc tcgtatgagc gcgcaggagc agctggagcg
     2341 catgcgtaga aaccaagcat gcgggctccc tcttcctcgc cctacctccc cgaggctcct
     2401 gaccctgggg aggacactgt ccccagctcc acgccagcct gacatggaac agaggcctat
     2461 tgttggagct gcgaaatggc tcaggagttc tgggtcctgg agtagtccca ggcactctgc
     2521 aacctgctca ccagtacctg gaggccaccg ggagcgagtg ctcagcctct cccaggctct
     2581 agctacagag gcttcccagt ggcacaggct gatggcagcc tctccaggca gaaatttgga
     2641 taccagggga gactgtctcc agccaagccc acagcctccc agtgaagaac tgccccaggt
     2701 cacctcgtcc ccagctcctc acaaggctac ttctgctacc acagggttct catgccaagg
     2761 cagccggaga ggcctggccc catgggaggc caggtgggac cctgggaagg cccctccagc
     2821 tctgacccag gaagaggggg catggccctt cagagtcact ctgctgcagt ccagcttttg
     2881 actcccatct ttatactgag ccctacaagc tggaagcaca actttgaggt gtgggaccat
     2941 tcaggaccac aggggagagg ttcattccag catgtattct aggagggcca gggccgctat
     3001 ggtcaaagat tgattttccc aacactgtcc aaaattggat gaaaactttg aactattagt
     3061 caataaatag cttttattct ctc
//
