LOCUS       NM_176916               3571 bp    mRNA    linear   ROD 27-JUL-2024
DEFINITION  Mus musculus phospholipase D family member 5 (Pld5), transcript
            variant 1, mRNA.
ACCESSION   NM_176916 XM_619703 XM_899943 XM_899950 XM_899955 XM_899960
            XM_899968 XM_915002 XM_923506 XM_923510 XM_923521 XM_923527
VERSION     NM_176916.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3571)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3571)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3571)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643. PMID: 29144450]
REFERENCE   4  (bases 1 to 3571)
  AUTHORS   Adissu,H.A., Estabel,J., Sunter,D., Tuck,E., Hooks,Y.,
            Carragher,D.M., Clarke,K., Karp,N.A., Newbigging,S., Jones,N.,
            Morikawa,L., White,J.K. and McKerlie,C.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Histopathology reveals correlative and unique phenotypes in a
            high-throughput mouse phenotyping screen
  JOURNAL   Dis Model Mech 7 (5), 515-524 (2014)
   PUBMED   24652767
REFERENCE   5  (bases 1 to 3571)
  AUTHORS   Lopez-Juarez,A., Morales-Lazaro,S., Sanchez-Sanchez,R., Sunkara,M.,
            Lomeli,H., Velasco,I., Morris,A.J. and Escalante-Alcalde,D.
  TITLE     Expression of LPP3 in Bergmann glia is required for proper
            cerebellar sphingosine-1-phosphate metabolism/signaling and
            development
  JOURNAL   Glia 59 (4), 577-589 (2011)
   PUBMED   21319224
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK136888.1, BU609501.1, AC124684.3 and AC153644.3.
            
            On Dec 25, 2006 this sequence version replaced NM_176916.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK144116.1, SRR7345562.957872.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849375,
                                           SAMN00849377 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-764               AK136888.1         2-765
            765-1016            BU609501.1         430-681
            1017-1045           AC124684.3         16289-16317
            1046-3470           AK136888.1         860-3284
            3471-3571           AC153644.3         28382-28482
FEATURES             Location/Qualifiers
     source          1..3571
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 81.9 cM"
     gene            1..3571
                     /gene="Pld5"
                     /gene_synonym="B230365F16Rik"
                     /note="phospholipase D family member 5"
                     /db_xref="GeneID:319455"
                     /db_xref="MGI:MGI:2442056"
     exon            1..627
                     /gene="Pld5"
                     /gene_synonym="B230365F16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            628..764
                     /gene="Pld5"
                     /gene_synonym="B230365F16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            765..933
                     /gene="Pld5"
                     /gene_synonym="B230365F16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            934..1045
                     /gene="Pld5"
                     /gene_synonym="B230365F16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1046..1173
                     /gene="Pld5"
                     /gene_synonym="B230365F16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1174..1371
                     /gene="Pld5"
                     /gene_synonym="B230365F16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1372..1508
                     /gene="Pld5"
                     /gene_synonym="B230365F16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1509..1677
                     /gene="Pld5"
                     /gene_synonym="B230365F16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1678..1792
                     /gene="Pld5"
                     /gene_synonym="B230365F16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1793..3571
                     /gene="Pld5"
                     /gene_synonym="B230365F16Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggggcccggg ttccagttgg tgcggagcag cctcgagcgg agctcccgct cgggaccgca
       61 gcggcaggcg acgtcgcggc cacctccgct gcaccctgac ttctgccact cgggagcagg
      121 catccactcc ttcccggtct ccctttgtcc agtcccccca tccgctccct cccccacccc
      181 ttctcccatc ctctaccctg cgacaccctc ccgcctctgt ccctcttccc gtgtccccgc
      241 tccagtgcct ctagccagcg cgctgcacac cccttggaag atcagcaccc cgtgttctcc
      301 gagggcgatc ggcaccctgt gcacccctct ctctccttca gctccatctc accgcccgcc
      361 tggcctctcg ctctctggcg gctccttgct cctatcccga gtgggttgcg cgtcgggcag
      421 ccgcctggtc atgtcaggat ggagatccgg cagcacgagt ggctctcggc ctccccccac
      481 gagggcttcg agcagatgag gttgaaaagc cgccccaagg aaccctcgcc cagcctgacc
      541 cgagtgggcg cgaacttcta cagcagtgtc aagcagcagg actacagcgc cagcgtctgg
      601 ctccgaagga aagataaact ggaacactct cagcagaagt gcatcgtgat cttcgctctg
      661 gtctgctgct tcgccgttct ggtcgctctc atcttttcag cggtggacat catgggagag
      721 gatgaggatg gactctcaga gaagaattgc caaaataaat gtcgaattgc tcttgtggaa
      781 aacattcctg aaggccttaa ctactctgaa gatgccccgt ttcacttacc gctcttccaa
      841 ggctggatga acttgctcaa catggccaaa aagtctgtgg acatagtgtc ttcccattgg
      901 gacctcaacc acacacaccc agctgcatgt cagggtcaac gtctctttga gaagttgctc
      961 cagctgacgt cgcaaaacat cgaagtcaag ctggtgagcg acgtgaccgc agattcaaag
     1021 gtattagaag ccttgaagtt aaagggtgct gaggtgacat acatgaacat gaccgcctac
     1081 aacaagggcc ggctgcagtc gtccttctgg attgtggaca aacagcatgt gtacattggc
     1141 agtgcaggct tagactggcg atcgcttgga cagatgaaag aactcggtgt catcttctac
     1201 aactgcagct gcctggtcct agatttacaa aggatattcg ctttatatag ctcattaaaa
     1261 ttcaagagca gagtacctca gacctggtcc aagagactct atggagtcta tgacaatgag
     1321 aagaagcttc agctccaatt gaacgaaacc aagtcacagg cctttgtgtc gaactctcct
     1381 aaactctttt gccctaaaaa cagaagcttt gacatcgatg ccatctacag tgtgattgac
     1441 gatgccaaac agtacgtgta cattgcggtc accgactacc tgcctatctc cagcacgagc
     1501 agcaaaagga cttactggcc agatttagat gggaagataa gagaagcatt agttttacga
     1561 agcgttaaag tccggctgct cataagcttc tggaaggaga ctgatcccct cacgttcaac
     1621 ttcatctcgt ctcttaaagc tatttgcact gaaatagcca actgcagttt gaaagttaaa
     1681 ttttttgatc tggaaagaga gaatgcttgt gcaacgaaag aacaaaagaa tcagaccttt
     1741 cccaaattaa accgcaacaa gtacatggtg acagacgggg cagcttacat cggaaatttt
     1801 gactgggtag ggaatgactt tacccagaac gctggcacgg gccttgtcat caaccaggca
     1861 gatgtgagag acaacaggag catcattaag caactgaagg acgtgtttga gagggactgg
     1921 tattcgcctt atgccaaatc catacagccc accaaacaac cgaactgttc aagcctgtcc
     1981 aaactcaagt ctccctccaa gcaacctgcc atggccaatg ccaccgggag ggagccgctg
     2041 agcgtatagc tcactaacag acacacaagg cttcagacca aatgcaggaa ggactagagg
     2101 aaagacaaca atttactaca tcttttcttt tattaaggag aaataaaaag cacacttatt
     2161 taaaatgttc tctgaatgac atgtaatatc tagctaacaa catcttagca ctgtatatta
     2221 aatttaagac ttttgtatct atgagctctg acagagaatg ttgttctggc ctaggagtta
     2281 gtttttaatg actgcaaaca cattttacga cttggttctt gtctcctgat tcttactggt
     2341 tttagaatct tttctgctga cccatcagca ctggttttaa gaagaataac atgaggtgag
     2401 ccctttcctt taatattgct gaattctgga attagaggaa ggggggagaa gatgcagaca
     2461 gaaccaagca tctgccctga catatcctct ctaagaccta tccaggcagc tgagcacagg
     2521 cacctccatt tcatgccagc cttcaagact tctgaaaaac actcatttct gtccccttgt
     2581 tccttgtctt ctgataccag ggttttgagg gtatcagtct gtcttctgac aaacatgttc
     2641 ttgttttaca tcatccttgg attcatctca gcattagttc aaaaagtgag aatgtcttgg
     2701 ggaaatgata tgaattcccc agaatgtata cagaatggaa atcagtcttt cactttctcc
     2761 tttcaattac attttttaaa cacacacaca cacacacaca cacacacaca cacacacaca
     2821 cacatatcct ttcctcaagc tccaaaaaaa aaaaaaagaa agaaaaaaaa aagaaatgaa
     2881 gtgcccctgc taatacccag caagccatta agtctgcatt tgaagaataa agcagtttca
     2941 catttctgtt tggttaacag tattataaag gaaaggtcta tgcgtcggtg gattttaatt
     3001 tatttagaat tattatgctg ttaagagtat gccagcaaat gtttataata gagctattta
     3061 atataccttc tgctatttaa tataccaaat gcttttcaga caaatgcaat ttaaatactg
     3121 tgcttaacat attttactaa gaaacagaaa tattggatta ctgttctata atgtcattgt
     3181 gtgttgtttt atatctatat aatatataat cctgtattaa aaaagactgt tggtacatga
     3241 gaggggtgtg acctcttcag ggccagagga agtggtcaag atgcctatgc ccagtgtggc
     3301 tcctgactct gtgctcagaa cagagccctt ccctctttgg ccccggtttt ctattgttaa
     3361 tgtagacaat aatcctcacc tacctcgcaa ggatgctgtc atggtaggcg atatttataa
     3421 gttgtttttg aaatcaaaag aacctatata aatgctaagc attaacattg cataatcttt
     3481 ttcttgaaat aatctctgtg gtatcctggt agcaccaata ccaggcactc tcccgaagaa
     3541 tccagagggc aaaataaagc actttctgtt t
//
