LOCUS       NM_001134480            7352 bp    mRNA    linear   ROD 15-DEC-2024
DEFINITION  Mus musculus phosphatidylinositol-specific phospholipase C, X
            domain containing 2 (Plcxd2), mRNA.
ACCESSION   NM_001134480 XM_001481102 XM_489641
VERSION     NM_001134480.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7352)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7352)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ104359.1, BC151059.1 and BC049364.1.
            
            On or before Sep 4, 2008 this sequence version replaced
            XM_489641.5, XM_001481102.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660811.219973.1,
                                           SRR1660821.114502.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-398               CJ104359.1         1-398
            399-2442            BC151059.1         1-2044
            2443-7352           BC049364.1         1-4910
FEATURES             Location/Qualifiers
     source          1..7352
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 30.45 cM"
     gene            1..7352
                     /gene="Plcxd2"
                     /gene_synonym="EG433022; PLCXD-2"
                     /note="phosphatidylinositol-specific phospholipase C, X
                     domain containing 2"
                     /db_xref="GeneID:433022"
                     /db_xref="MGI:MGI:3647874"
     exon            1..720
                     /gene="Plcxd2"
                     /gene_synonym="EG433022; PLCXD-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             558..1580
                     /gene="Plcxd2"
                     /gene_synonym="EG433022; PLCXD-2"
                     /note="phospholipase C X-domain containing protein 2"
                     /codon_start=1
                     /product="PI-PLC X domain-containing protein 2"
                     /protein_id="NP_001127952.1"
                     /db_xref="CCDS:CCDS49863.1"
                     /db_xref="GeneID:433022"
                     /db_xref="MGI:MGI:3647874"
                     /translation="MLAFRKARRKLRMGTICSPNPSGTKTASEVCNADWMASLPAHLH
                     NVPLSNLAIPGSHDSFSYWVDEKSPVGPDQTQAVIRLARISLVKKLMKKWSVTQNLTF
                     REQLEAGIRYFDLRVSSKPGDTDQEIYFIHGLFGIKVWDGLMEIDAFLTQHPQEIIFL
                     DFNHFYAMDESHHKCLVLRIQEAFGNKLCPACSVESMTLRSLWEKKYQVLIFYHCPFY
                     KQYPFLWPGKKIPAPWANTTSVQKLILFLETTLSERAPRGAFHVSQAILTPRVKTIAR
                     GLVGGLKNTLVHRNLPAILDWVKTQKPGAMGVNIITSDFVDLIDFATTVIELNDLLED
                     RALTKC"
     exon            721..1181
                     /gene="Plcxd2"
                     /gene_synonym="EG433022; PLCXD-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1182..1423
                     /gene="Plcxd2"
                     /gene_synonym="EG433022; PLCXD-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1424..7337
                     /gene="Plcxd2"
                     /gene_synonym="EG433022; PLCXD-2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7317..7322
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Plcxd2"
                     /gene_synonym="EG433022; PLCXD-2"
                     /note="hexamer: AATAAA"
     polyA_site      7337
                     /gene="Plcxd2"
                     /gene_synonym="EG433022; PLCXD-2"
                     /note="major polyA site"
ORIGIN      
        1 agagtcccgg ggctgccggt tactcttctg agagcccttc agaaaagcac agggcagtgg
       61 gcagagaagc cagggggcgg gggtgcaggc aggcccagcc tgtgtaccag cccggggaaa
      121 cccacggaag cacccatgaa caagagatgg tgcaacccgg gtgcgcacgt gtgtgcagcc
      181 cgctggcacg tctctatgcc ctgtgggcac ctgtcgtgtg agtagctccg ggtgtggctg
      241 ttcctggatg ttgtgggttt caggaaggtt tgtatcttcg ggcctgcctc ccccgtctcc
      301 agaggggaac taagaagttt aactgaccag ggactgagga gattaaagga gtggatctca
      361 gtggcaaggc gaagagggtg gggactgcgg gagcagcagg caggggagca cctatttgac
      421 ccatctccca gctagaaaag gatcttgaaa agactggcgt gacccatgtg ctctgaaatg
      481 tttagagagc cccgagcggt gatgaccaca gagtgagtgg cactagactg agcctgtcta
      541 aatcgtggac gacagggatg cttgcattta gaaaggccag aaggaaactc aggatgggta
      601 ccatctgctc tcccaatccc agcgggacaa agacagcctc ggaggtctgc aatgccgact
      661 ggatggcctc gctccccgct cacctccaca acgtccccct ttccaatctg gcaatcccag
      721 gctcccatga ttcattcagc tactgggtag atgaaaagtc cccagtgggg cctgaccaaa
      781 cccaagctgt catacgcctt gcccggatct ccttggtgaa aaagttaatg aagaaatggt
      841 ctgtaactca gaacctgacc ttcagggagc agctggaggc tgggatccgc tactttgacc
      901 tacgggtgtc ttccaagcct ggagacactg accaggagat ctacttcatc cacgggctct
      961 ttggcatcaa ggtttgggat gggttgatgg agattgatgc cttcctcact cagcaccctc
     1021 aagagatcat cttcctggat ttcaaccact tctatgccat ggatgagagc caccacaaat
     1081 gcctggttct gcggatccag gaggcctttg ggaacaagct gtgcccagcc tgcagcgtgg
     1141 aaagcatgac actgcggagt ctgtgggaga aaaagtacca ggttctcatt ttctaccact
     1201 gtcccttcta caagcaatac ccattcctgt ggccagggaa gaagattccg gcaccctggg
     1261 caaacaccac gagtgtgcag aaactgatcc tcttcttgga gaccaccctg agtgagcgag
     1321 ctccacgtgg ggccttccat gtctcccagg ccatcctcac gccaagagtg aagactattg
     1381 ctcgaggcct ggtggggggc ctcaagaaca cactagttca caggaatctc cctgccatcc
     1441 ttgattgggt gaagactcaa aagcctggcg ccatgggtgt caacatcatc acatctgact
     1501 tcgtggacct gatagacttt gccacgactg tgattgagtt gaacgacctc ctagaggatc
     1561 gagctctgac taagtgttga attcatgctt tgtttaattt gaggttgagg ttgttgatat
     1621 aaggtaggat tctagagggt tctaggaaag atgactcact tgtaggcagt cacggggaag
     1681 tgaggaagga aaagaaggcc ctctctttcc tcacatagct acttggactt aaaaaaaaat
     1741 ctaaggggtt tccatgcatt ttcccccaaa gacactttta caaacttaag tctaagagaa
     1801 gaatgcatgt ttcctatggt taacatcagg atctccccag tggcttgtgg tggcaaatgg
     1861 aagatggaag catccttttc aggttctgtg ggctatgcaa catcctaact ggcccagctt
     1921 cctcttgtct tctgtggtca tttgagcctg tgtgaagact aagtcagaaa ggcattcctg
     1981 gtcagaagaa tggcacatgt gagcgtggac catcctgaga gctctctgcc atcaacccag
     2041 agctctaagg ggctcctatg gagccaagaa ccaggtctct catgaactgt acagtatcac
     2101 cactttctac gagagcaaga tatgtttatt atcacagtgc tcagccacag gctggctctg
     2161 catatcttgg gctagaagtg ggcaccttta ttcttcatat aagcagtgca ccctaccctt
     2221 ggcatcagaa aaagtatttt cttattttaa tgtattttgg gccctatctt taaaatgata
     2281 gggacagtag ttggaaagtc ttttctgtga gggcccaata cagactaaac atgcatgttg
     2341 gttgcatgcc agagttcttt gatttcgttc tgtatccttc tccccaaacg actatcaggc
     2401 aagtacctgg atcattttgg ccaagtcctc tggagtgagg tcttcaagcc tgagagcaga
     2461 atcctgtctt attgattatc tgtctgggac ctggtctgct gcacgacaca atgcttgtct
     2521 atgacaccat ggaggaggct gacacaggat gcgtgggaac gtgcaatgga attgaaggac
     2581 gatggtccaa gtgggtttgg agccagtctg taactccttg caaacaagac tacctcgggg
     2641 acatttagca tgactcgtat gtcatccagt gagggaaaaa aaaagcaatg ctggacattt
     2701 ctgcttgttt ttccatttag tctacttcct gtgagttgtt cagccaactg cctttgcatg
     2761 agggcttgga gacacaaggg gaactttttt ttttaattga taagaggtgc tttttattga
     2821 taagagccct cttttgtttc atttgctttg tttgagtatt tattaattta tttattcata
     2881 gagtaaggat ctgcagtgtt ccctgcctga agaacactca cagatgtttg ctggactttt
     2941 cctacccagg atgctgctgt ggtcatccac tcatgcactg catggcgcat ctcaggggct
     3001 gtgagtgacc tcgtaacttt gctgtaggtg ccctaccgca accccagtcc tgctggggac
     3061 aatgtatagg tgtggatgtg atccagatat aggaagctac tgccaaaggc atgcacaggg
     3121 acagaagtga aagggtcatg agaaactata ctacacaggc gtatagagca ttgggaagag
     3181 tagaactagg aataatggct gagcatacac gtgagtgtgc tttgctaacc ttcagcccta
     3241 tttgagaatc cctaaggagt gtcagattcc acattcctaa ggaggaatat aaacaggcag
     3301 ggctgggtgg gcatgcatat ttacagagat tgctggacct tctagtactt ctcacgtctc
     3361 tccctttgat tgccttgtca gttgtgcatg ctgcctgccg gtggggatat cttgggtgag
     3421 ctattgaaaa catgcatgcc ccgaatggct gaccatctga cctttctttc cctaatgtaa
     3481 tttaggcctt gactttttac ttccatagtt cacggaggcc acagcacaaa ggcctctgag
     3541 aaaacctgat ttggcttctc ctgttcttga gtttgaatcc tgcccagagg tggcttctgg
     3601 aatgttcttg tcaaacttgg cagagccttt ctgcacaggg cttcctcatt gtgtaggagt
     3661 gcataccctc accatcttca tttcccttcc gttgtgatgc tctacagaga ggctcccaaa
     3721 accttagcct accctcaggt ttttattttt gtttttttat tgttgcattc ttttttggtt
     3781 ttggttttaa ctatcagtta gttacaaggg actagatcac tcccttctgt taaccctttg
     3841 ttacttggca aagagataag gaggcaacag gagaggcatt ctgctctgtt ttatttgcgc
     3901 ctcagctttg tccgggtgct tggtgctatg gagcctggtg tgtcagcacc aaatggatac
     3961 cagtttcact ttaaggctgc agactgttct gtgaactgtt tacttcgttt tctccctttg
     4021 ctcttaaata cacagttgta tttcacttct gacatttaag tacacctcag tgtttgcatc
     4081 ctgcaccatc aagtctaaca cagaagcaca gagcacttcc aaggccacgt gtatgggccc
     4141 cttctcccac agtgagtaca tgaatgtata tcaccggctc atccatgctg cgttagggtc
     4201 ccagcctcgc tgttattctg aacatctgag aggtagggag aggattattc acagttcctc
     4261 ccagggatta ctcaactctg ccccaagaac aggcttccaa tgttggaaaa gctgcatgca
     4321 ttgaagctgt gccttgaaga ccaggcagaa acttaagtga attggacaga gaaaaagtag
     4381 aacatgggcc ccagagctca ttctgccata gttttcaagt gagagctctg acccaaatat
     4441 atcacatgtt ctctaatatc gggggagtca ttcagatttt aaaaaaaggt tctcatagtt
     4501 attcagaatc aacttcaaga gcagctaaaa tgctgcttga ttaacttagt tggggttcat
     4561 tcctgtttgg aaatttaact gggttcttcc tgaactctac accattccaa cacagccata
     4621 ttttcttaat ggcccagacc tagatgcccc taggtctctg tggcttagaa tggtgtctca
     4681 gggcttgaat actgagttta tcagaagttc caagtatgtt atggatggag acaattttct
     4741 tcggattgaa tggagaagtc aggatggatg tgatggaaga gattggtgag tgtttaagga
     4801 tttggtctga gatcatggca gatcttagaa gtcatgcaaa aaaaatactt atatttgctg
     4861 cataagattt gatagtgatt gttttctcta gtgctgggtc cagaccctga attttttaga
     4921 actgttaatc tagagtttag agttcaaatc caatatttta tatgcatgca aagaaaagca
     4981 catgacctga ggagagataa tgacagacct taagaatcct ggatattttt ttatagtctc
     5041 atgttcatgt ctggaaattc atgcttctat ttaggaaggc aatgaaatga agcattctga
     5101 gatgaaatga agctttctga tgtgtctgga tatttgcatt ttttccagtt gttagggtta
     5161 gggtcaaggg tcaggggtta gggttgtggt cagtggtcag aggttaggag gcatctccaa
     5221 agagacataa tacacataag cacaaagtgt aaggtggaga cccagaagaa atccaggctg
     5281 aaaggaaact gctgtttcct ctgagaagca aaaggactgc atgctgacat catttttatg
     5341 atgtccttga ttgtttgtta tgttctggga aacagaactg actaatgaat gagccacggt
     5401 cacgagatct cccttaactg agcaactggt cctgggctaa gctgtcattg gttcttccat
     5461 ctttaataat gacacaaatc tcaggtggct gattcataaa ttacgaggtc ctagagctca
     5521 gcctgaatgc cttgtgctct agggatgcac ccttagcatg attctccctt ttgtgcacat
     5581 gtgcagagaa tatggttaga gtcatgcaag aatgtggtgc aggccgatgg agttcaacga
     5641 tgtgttgtac gtttcagggt ggacataatg tgtggggctc aatgaaatct gccaaaatgt
     5701 acatgggccc ctgggaggca ggttttctct agaggaaaca gtagacattg agagtatcaa
     5761 acatccaagc tgacaggaat ctcatttggt gcagcataga agagcataga tgtccttgtc
     5821 aatttcatta cctgtctagc gaatcttaac cctctaccac agctgcttcc ttgtaggtga
     5881 ttccacagtt tcatttctca gtagtgtcac cttaggacac agggagagtg gactgattga
     5941 atagcaagtg gtgtcagtat aaacttctcc tcaattccag aaggttctaa tcagcttgtg
     6001 actgccccaa gagacctcct acgtccacag cctttggatt ccccagcttc ctgctgcaca
     6061 cactgacact aacggccatg tctcttgagc tagcctaact ccgaagcaac cctacaatga
     6121 tgctattgat tcttccttta aaaaaaaaaa aaggaaaaaa aaaactatgt cttagacagt
     6181 gtaaaaatat tctaaatttt atcaaactca ttttaaaaca aaatggttcg aataagacaa
     6241 ttctctcttc tctttgggcg aaattcggaa gcacatttgt tgaggcaact gcatcagtcg
     6301 actcgaggca gtttcccatc gtccttcctc attcccttca tagaaagcta cttttccccc
     6361 tcttgtcact agcatctcca tcatctgcca atgaccgcgt cacaagatgc tgacagagac
     6421 tctgctctgt ccatgttggt ggttgctctt tagccttctc caatgcacta ttctgcctcc
     6481 tgatcccacc cagtcattag aactatgctt aattagagcc ctgaaattgg gaccaatgtt
     6541 caattcatat agcacaggct tgctcacagt gttaagccca ctaagaagca taacactttg
     6601 aaaagtcata taggcctttg gcaactctgt atagttgcaa tgtcacacct gttatcggtt
     6661 tatagcacta ataatatgtc aaagatagat ctatagtatc aagatgataa ctcttagatc
     6721 atgttctaga aataataata ccttgctgct attattaccc cagtatgaat aagtattaaa
     6781 tgcagattgt atatgcatta tttgtattat gtacatacca actgtaatac ttagcctccc
     6841 tgatcagtaa tttaaaatta cagaaattgt catagtaaaa atcagtcttg gtcagttcag
     6901 ataatttgtg catctgataa atgctgtaat ggagattata ttttgtcttc tattcattga
     6961 tttacactac gatgcatgtg gtttgctaaa cttaagaaat aataatcaat ttttaccaat
     7021 tttaaggtta gagataaaat tgtgcatata tgctacttga cactctgaga tgtatcttgt
     7081 ggcctgattg tcaatgtcat atacacttca cctgccttct ttccctctag gaagtagttg
     7141 ttgaattgca tctcttcttt cttgaaacct ggattaaatc acttgattca tcctaaacta
     7201 ttgtgaagcc acagtacctc attttaactg tgaaaaaaaa aagtgttaat agatttgacc
     7261 atatgatgtg tttccttgtg tttgacttga gccagttaaa aaggtttaaa cctagtaata
     7321 aacatgaatc tttaataaaa aaaaaaaaaa aa
//
