LOCUS       NM_139198                703 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus placenta-specific 8 (Plac8), transcript variant 2,
            mRNA.
ACCESSION   NM_139198
VERSION     NM_139198.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 703)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 703)
  AUTHORS   Wan,Y., Yang,S., Li,T., Cai,Y., Wu,X., Zhang,M., Muhammad,T.,
            Huang,T., Lv,Y., Chan,W.Y., Lu,G., Li,J., Sha,Q.Q., Chen,Z.J. and
            Liu,H.
  TITLE     LSM14B is essential for oocyte meiotic maturation by regulating
            maternal mRNA storage and clearance
  JOURNAL   Nucleic Acids Res 51 (21), 11652-11667 (2023)
   PUBMED   37889087
REFERENCE   3  (bases 1 to 703)
  AUTHORS   Yang,X., Shui,X., Dai,X., Hao,S., Ke,F., Zhu,L. and Chen,X.
  TITLE     PLAC8 promotes EV71 infected inflammatory lesion by disturbing
            Th-cell-related cytokines release in neonatal mouse
  JOURNAL   Virology 564, 39-45 (2021)
   PUBMED   34653773
  REMARK    GeneRIF: PLAC8 promotes EV71 infected inflammatory lesion by
            disturbing Th-cell-related cytokines release in neonatal mouse.
REFERENCE   4  (bases 1 to 703)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 703)
  AUTHORS   Slade,C.D., Reagin,K.L., Lakshmanan,H.G., Klonowski,K.D. and
            Watford,W.T.
  TITLE     Placenta-specific 8 limits IFNgamma production by CD4 T cells in
            vitro and promotes establishment of influenza-specific CD8 T cells
            in vivo
  JOURNAL   PLoS One 15 (7), e0235706 (2020)
   PUBMED   32639988
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 703)
  AUTHORS   Galaviz-Hernandez,C., Stagg,C., de Ridder,G., Tanaka,T.S., Ko,M.S.,
            Schlessinger,D. and Nagaraja,R.
  TITLE     Plac8 and Plac9, novel placental-enriched genes identified through
            microarray analysis
  JOURNAL   Gene 309 (2), 81-89 (2003)
   PUBMED   12758124
REFERENCE   7  (bases 1 to 703)
  AUTHORS   Abbott,D.E., Pritchard,C., Clegg,N.J., Ferguson,C., Dumpit,R.,
            Sikes,R.A. and Nelson,P.S.
  TITLE     Expressed sequence tag profiling identifies developmental and
            anatomic partitioning of gene expression in the mouse prostate
  JOURNAL   Genome Biol 4 (12), R79 (2003)
   PUBMED   14659016
REFERENCE   8  (bases 1 to 703)
  AUTHORS   Rissoan,M.C., Duhen,T., Bridon,J.M., Bendriss-Vermare,N.,
            Peronne,C., de Saint Vis,B., Briere,F. and Bates,E.E.
  TITLE     Subtractive hybridization reveals the expression of
            immunoglobulin-like transcript 7, Eph-B1, granzyme B, and 3 novel
            transcripts in human plasmacytoid dendritic cells
  JOURNAL   Blood 100 (9), 3295-3303 (2002)
   PUBMED   12384430
REFERENCE   9  (bases 1 to 703)
  AUTHORS   Yanagi,Y., Takezawa,S. and Kato,S.
  TITLE     Distinct functions of photoreceptor cell-specific nuclear receptor,
            thyroid hormone receptor beta2 and CRX in one photoreceptor
            development
  JOURNAL   Invest Ophthalmol Vis Sci 43 (11), 3489-3494 (2002)
   PUBMED   12407160
REFERENCE   10 (bases 1 to 703)
  AUTHORS   Ko,M.S., Threat,T.A., Wang,X., Horton,J.H., Cui,Y., Wang,X.,
            Pryor,E., Paris,J., Wells-Smith,J., Kitchen,J.R., Rowe,L.B.,
            Eppig,J., Satoh,T., Brant,L., Fujiwara,H., Yotsumoto,S. and
            Nakashima,H.
  TITLE     Genome-wide mapping of unselected transcripts from extraembryonic
            tissue of 7.5-day mouse embryos reveals enrichment in the t-complex
            and under-representation on the X chromosome
  JOURNAL   Hum Mol Genet 7 (12), 1967-1978 (1998)
   PUBMED   9811942
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC109196.12.
            
            On May 28, 2019 this sequence version replaced NM_139198.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC010789.1, AK007369.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849377, SAMN00849378
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-61                AC109196.12        85183-85243
            62-199              AC109196.12        94626-94763
            200-324             AC109196.12        97512-97636
            325-440             AC109196.12        100793-100908
            441-703             AC109196.12        103400-103662
FEATURES             Location/Qualifiers
     source          1..703
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 48.49 cM"
     gene            1..703
                     /gene="Plac8"
                     /gene_synonym="C15; D5Wsu111e"
                     /note="placenta-specific 8"
                     /db_xref="GeneID:231507"
                     /db_xref="MGI:MGI:2445289"
     exon            1..61
                     /gene="Plac8"
                     /gene_synonym="C15; D5Wsu111e"
                     /inference="alignment:Splign:2.1.0"
     exon            62..199
                     /gene="Plac8"
                     /gene_synonym="C15; D5Wsu111e"
                     /inference="alignment:Splign:2.1.0"
     CDS             91..429
                     /gene="Plac8"
                     /gene_synonym="C15; D5Wsu111e"
                     /note="onzin"
                     /codon_start=1
                     /product="placenta-specific gene 8 protein"
                     /protein_id="NP_631937.1"
                     /db_xref="CCDS:CCDS19464.1"
                     /db_xref="GeneID:231507"
                     /db_xref="MGI:MGI:2445289"
                     /translation="MAQAPTVIVTQPGFVRAPQNSNWQTSLCDCFSDCGVCLCGTFCF
                     TCLGCQVAADMNECCLCGTTVAMRTLYRTRYGIPGSICDDYMVTLFCPVCSVCQLKRD
                     INRRRAMNAF"
     exon            200..324
                     /gene="Plac8"
                     /gene_synonym="C15; D5Wsu111e"
                     /inference="alignment:Splign:2.1.0"
     exon            325..440
                     /gene="Plac8"
                     /gene_synonym="C15; D5Wsu111e"
                     /inference="alignment:Splign:2.1.0"
     exon            441..703
                     /gene="Plac8"
                     /gene_synonym="C15; D5Wsu111e"
                     /inference="alignment:Splign:2.1.0"
     regulatory      681..686
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Plac8"
                     /gene_synonym="C15; D5Wsu111e"
                     /note="hexamer: AATAAA"
     polyA_site      695
                     /gene="Plac8"
                     /gene_synonym="C15; D5Wsu111e"
                     /note="major polyA site"
     polyA_site      701
                     /gene="Plac8"
                     /gene_synonym="C15; D5Wsu111e"
                     /note="major polyA site"
ORIGIN      
        1 ctatttgtag taagactcaa ccccagacca caggaccggt tctgcccaac ccttttgaac
       61 tacttggtct tttgagacct cgcatcgaag atggctcagg caccaacagt tatcgtgact
      121 caacctggat tcgttcgtgc tccccaaaat tccaactggc agaccagcct gtgtgattgc
      181 ttcagtgact gcggagtctg cctctgtggg accttttgtt tcacttgtct tggatgtcaa
      241 gtggcagctg acatgaatga gtgttgtctg tgtggaacaa cggtggccat gaggactctc
      301 taccgaaccc gatacggcat tcctggatct atttgtgatg actacatggt cacactcttc
      361 tgtcctgttt gctctgtgtg ccaactcaag agagacatta acaggaggag agccatgaac
      421 gctttctaag gagctggatg gcaagagctc tggctgaaga agctcaactc agcacacact
      481 ccttcagcct gagatttttc aaatctttgg caactgagat gggatggatc catttaatta
      541 gagaacggtg aaatctttct agttgggctt tttgatttat tttaaatgga tattgctctt
      601 tgacttggtt tcttcttgct cccatatcat caaatattgg agcctataat ttttttacct
      661 tacattttag gtagaaacca aataaaagat tttgctaaga aga
//
