LOCUS       NM_012044                851 bp    mRNA    linear   ROD 17-SEP-2024
DEFINITION  Mus musculus phospholipase A2, group IIE (Pla2g2e), mRNA.
ACCESSION   NM_012044
VERSION     NM_012044.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 851)
  AUTHORS   Taketomi,Y., Higashi,T., Kano,K., Miki,Y., Mochizuki,C.,
            Toyoshima,S., Okayama,Y., Nishito,Y., Nakae,S., Tanaka,S.,
            Tokuoka,S.M., Oda,Y., Shichino,S., Ueha,S., Matsushima,K.,
            Akahoshi,N., Ishii,S., Chun,J., Aoki,J. and Murakami,M.
  TITLE     Lipid-orchestrated paracrine circuit coordinates mast cell
            maturation and anaphylaxis through functional interaction with
            fibroblasts
  JOURNAL   Immunity 57 (8), 1828-1847 (2024)
   PUBMED   39002541
REFERENCE   2  (bases 1 to 851)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 851)
  AUTHORS   Nakamura,A., Sakai,S., Taketomi,Y., Tsuyama,J., Miki,Y., Hara,Y.,
            Arai,N., Sugiura,Y., Kawaji,H., Murakami,M. and Shichita,T.
  TITLE     PLA2G2E-mediated lipid metabolism triggers brain-autonomous neural
            repair after ischemic stroke
  JOURNAL   Neuron 111 (19), 2995-3010 (2023)
   PUBMED   37490917
  REMARK    GeneRIF: PLA2G2E-mediated lipid metabolism triggers
            brain-autonomous neural repair after ischemic stroke.
REFERENCE   4  (bases 1 to 851)
  AUTHORS   Watanabe,K., Taketomi,Y., Miki,Y., Kugiyama,K. and Murakami,M.
  TITLE     Group V secreted phospholipase A2 plays a protective role against
            aortic dissection
  JOURNAL   J Biol Chem 295 (30), 10092-10111 (2020)
   PUBMED   32482892
REFERENCE   5  (bases 1 to 851)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643. PMID: 29144450]
REFERENCE   6  (bases 1 to 851)
  AUTHORS   Plageman,T.F. Jr. and Yutzey,K.E.
  TITLE     Microarray analysis of Tbx5-induced genes expressed in the
            developing heart
  JOURNAL   Dev Dyn 235 (10), 2868-2880 (2006)
   PUBMED   16894625
REFERENCE   7  (bases 1 to 851)
  AUTHORS   Song,H., Lim,H., Paria,B.C., Matsumoto,H., Swift,L.L., Morrow,J.,
            Bonventre,J.V. and Dey,S.K.
  TITLE     Cytosolic phospholipase A2alpha is crucial [correction of A2alpha
            deficiency is crucial] for 'on-time' embryo implantation that
            directs subsequent development
  JOURNAL   Development 129 (12), 2879-2889 (2002)
   PUBMED   12050136
  REMARK    Erratum:[Development 2002 Aug;129(15):3761]
REFERENCE   8  (bases 1 to 851)
  AUTHORS   Suzuki,N., Ishizaki,J., Yokota,Y., Higashino,K., Ono,T., Ikeda,M.,
            Fujii,N., Kawamoto,K. and Hanasaki,K.
  TITLE     Structures, enzymatic properties, and expression of novel human and
            mouse secretory phospholipase A(2)s
  JOURNAL   J Biol Chem 275 (8), 5785-5793 (2000)
   PUBMED   10681567
REFERENCE   9  (bases 1 to 851)
  AUTHORS   Valentin,E., Ghomashchi,F., Gelb,M.H., Lazdunski,M. and Lambeau,G.
  TITLE     On the diversity of secreted phospholipases A(2). Cloning, tissue
            distribution, and functional expression of two novel mouse group II
            enzymes
  JOURNAL   J Biol Chem 274 (44), 31195-31202 (1999)
   PUBMED   10531313
  REMARK    Erratum:[J Biol Chem 2000 Jan 21;275(3):2246]
REFERENCE   10 (bases 1 to 851)
  AUTHORS   Zambrowicz,B.P., Friedrich,G.A., Buxton,E.C., Lilleberg,S.L.,
            Person,C. and Sands,A.T.
  TITLE     Disruption and sequence identification of 2,000 genes in mouse
            embryonic stem cells
  JOURNAL   Nature 392 (6676), 608-611 (1998)
   PUBMED   9560157
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AL844178.7.
            
            On Nov 17, 2006 this sequence version replaced NM_012044.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF112984.1, AF166098.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-131               AL844178.7         9120-9250           c
            132-205             AL844178.7         7696-7769           c
            206-344             AL844178.7         6703-6841           c
            345-451             AL844178.7         6416-6522           c
            452-851             AL844178.7         4378-4777           c
FEATURES             Location/Qualifiers
     source          1..851
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 70.57 cM"
     gene            1..851
                     /gene="Pla2g2e"
                     /note="phospholipase A2, group IIE"
                     /db_xref="GeneID:26970"
                     /db_xref="MGI:MGI:1349660"
     exon            1..131
                     /gene="Pla2g2e"
                     /inference="alignment:Splign:2.1.0"
     exon            132..205
                     /gene="Pla2g2e"
                     /inference="alignment:Splign:2.1.0"
     exon            206..344
                     /gene="Pla2g2e"
                     /inference="alignment:Splign:2.1.0"
     exon            345..451
                     /gene="Pla2g2e"
                     /inference="alignment:Splign:2.1.0"
     exon            452..851
                     /gene="Pla2g2e"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaaaagagac ctctctcagt agacggtgac tcagagctgc agggtgtacc aggcaggtgg
       61 acttggtccc catcaccttt gcaacaggga cagagcttgc agtacccaga tgcccctggg
      121 aggtggcaga gcaggctccc atgccccctg cctacctccc ccaggatgaa acctcccatt
      181 gccctggctt gcctttgcct cctggtgccc ctggctggcg ggaacctggt ccagtttgga
      241 gtgatgattg agagaatgac gggaaagcct gccctgcagt acaatgacta tggctgctat
      301 tgcggtgtcg gtggctccca ctggccagtg gacgagacgg attggtgttg tcatgcccat
      361 gactgctgct atggccgcct ggagaagctg ggctgtgacc ccaagctgga aaagtacctc
      421 ttctctatca ctcgagacaa catcttctgt gctggtagaa cggcttgcca gcggcatacc
      481 tgcgagtgtg acaagagagc cgctctctgc tttcgccaca acctgaacac ttacaaccgc
      541 aagtatgccc actaccccaa caagctgtgt actgggccca ccccaccctg ctgaggccct
      601 gctcggctcc atagccaccc caggctgctg cagtctcagg cccagagaag ctcggaaccc
      661 agattcctct cccagcagac tcatcccgcc ccccccagag atcatgagcc ctggtctctg
      721 gcctccagga ccacaccaga tccacgggat cagctgaaga agtcacggga ctcgtcagcg
      781 ctcacaagat ccactaagtc gcctctggca tctcaatacc ctcttctgaa taagagaagt
      841 ctattttcct g
//
